I chhungte pawhin, "I mit chu i pa mit ang chiah a ni," leh "I nuihzatthlak chu i nu ang mai a ni," an ti che a ni mai thei. Kan hmel lan dan te, kan mizia te, leh kan nu leh pa atanga kan hmuh thilte chu genes tiin kan sawi thin. Heng genes te hi kan nu leh pate hnen atanga kan rochun a ni. Mahse he genetic story hi kan ngaihtuah aiin a thuk zawk a, mak a ti zawk bawk. Vawiin hian chu thawnthu thuk takah chuan bung thar ber kan sawi dawn a, chu chu genomic medicine a ni . Hei hi technology thar a ni a, medical field-ah pawh danglamna nasa tak a thlen dawn a ni.
Genomic Medicine chu eng nge ni?
A awlsam zawngin sawi ila, Genetic medicine chu mi taksa chhunga gene zawng zawngte inzawmkhawmin taksa a nghawng dan zir chianna a ni. Hetiang hian han ngaihtuah teh. Brick pakhat atang hian in pum pui ngaihtuahna i nei thei lo. Mahse in blueprint kimchang i en chuan in chu eng ang nge a nih tih te, a pindan te, a kawngkhar leh kawngkhar te chu eng ang nge a nih tih te chu i hrethiam vek thei ang. Chutiang bawkin gene pakhat chauh chu chu brick ang a ni. Mahse i taksa (Genome) chhunga gene zawng zawng khawlkhawm chu chu in blueprint kimchang ang mai a ni. He blueprint chhungah hian i taksa a lo thanlen dan tur leh a lo thanlen dan tur hrilhfiahna kimchang tak a awm a. Heng thupek te hi DNA an tih molecule ah ziah a ni .
He field hi thil thar tak ni mah se, kum sawmhnih kalta chhung khan a lo thang chak hle a ni. Hei hi a chhan lian ber chu Human Genome Project , kum 2003-a zawh a ni a, khawvel hmun hrang hrang atanga scientist-te inzawmkhawmna programme lian tak a ni. A tum ber chu mihring taksaa gene awm zawng zawng hriatchhuah a, map a, an hnathawh dan hriatthiam a ni. Chutah chuan scientist-te chuan kan taksaah hian gene 20,500 vel a awm tih an hmuchhuak a.
He hriatna hmang hian doctor-te chuan natna ṭhenkhat , cancer leh naupang tê tê vei thei natna hlauhawm tak takte vei theihna hlauhawm zâwk chu tu nge ni tih an hre thei ta a ni. He technology hian nakin lawkah damlo tan enkawlna tha ber thlan nan a pui dawn bawk a ni.
Genetics leh Genomics hi eng nge an danglamna?
Heng thumal pahnih hi a chang chuan ri inang mahse, an pahnih inkarah hian danglamna chiang tak a awm. He inthlauhna hi hriatthiam a pawimawh hle.
Genetics lam thil a niGenetics chu mimal genes zir chianna a ni. Genomics chu genetic system zir chianna a ni a, chu chu gene zawng zawngte thawhhona a ni.
Entîr nân, gene mutation ṭhenkhat chuan natna a thlen thei tih i hre tawh mai thei. BRCA gene mutation nei te hian mi pangngai aiin hnute leh ovarian cancer vei an tam zawk hle. Thil ngaihtuah tur i neih chuan, chu gene bik enfiahna thisen test neihpui turin i doctor nen sawiho rawh . Chu chu genetics an ti a.
Mahse genomics hi hei aia zau zawk a ni. I taksa chhunga gene zawng zawng DNA sequence mapping a huam a ni. Hei hi genomic sequencing an ti a . Hei hi hna buaithlak tak angin lang mah se, tunah chuan technology thar siam chhuah a nih avangin hei hi a senso chu nasa takin a tlahniam ta a ni.
He danglamna hi a hnuaia table-ah hian sawifiah belh theih a ni.
| Nihphung | Genetics lam thil a ni | Genomics lam a ni |
|---|---|---|
| Ngaihtuah rawh | Gene pakhat emaw, gene engemaw zat emaw vel | Mi pakhat genes (Genome) zawng zawng chungchang |
| Bukna | Scope tawi tak a ni | A zau hle (Broad scope) . |
| Tum ber chu | Natna rochun leh mimal gene inzawmna zawng chhuah | Natna, boruak leh gene inzawmna buaithlak tak takte zir chianna |
| Entirna | BRCA gene testing hmanga hnute cancer hlauhawmna a awm | Natna hriat loh zawng zawng genome testing |
Ka genetic test (Genome Sequencing) pawh ka tihsak tur em ni?
Hei hi mi tam takin zawhna an neih a ni. Khawvel hmun hrang hrangah hetiang testing hi tih theihna hmun a awm tawh a. Mahse, hei hi mi zawng zawng mamawh tak a ni em?
Tuna kan dinhmun ngaihtuah chuan he test hi thil awmdan bik tlemteah chauh a tangkai ber a ni .
- Naupang damdawi lam dinhmun hriat harsa tak takte: Naupang ṭhenkhat chuan pianpui hrisêlna lama harsatna nei, rilru lama harsatna nei, ṭhanlenna tlai, a nih loh leh rilru hahna nei fo . Routine test hmanga a chhan hriat theih loh chuan genomic sequencing hmangin a chhan chu a hmu thei mai thei. A chhan hriat chian a nih veleh enkawlna chu tihdanglam theih a ni.
- Cancer vei thenkhat: Cancer thenkhat, a bik takin thisen cancer vei tan chuan he test hian an tan enkawlna tha ber leh tangkai ber thlang turin a pui thei a ni. Hei hi "precision medicine" kan tih chu a ni. Chu chu mi zawng zawng hnenah damdawi inang pek ai chuan i genes nena inmil tur treatment kan design tihna a ni.
Cancer i vei chuan hetiang test chi hi i doctor nen inbiakna neih a pawimawh . Cancer i neih chi hrang hrang a zirin, he test atanga thu hriatte hian i enkawlna kaihruaitu emaw, i natna kal zel dan hriatthiamna emaw a pui thei che a ni.
He genetic test hian eng nge a thatna leh a that lohna?
He technology hi a ngaihnawm hle a, thutiam ropui tak a keng tel bawk. Mahse coin sir lehlamah ang bawkin a thatna leh that lohna a nei a, chu chu ngaihtuah ngai a ni.
| Pros | Cons |
|---|---|
| I natna hlauhawmna hriat: Lung natna ang chi natna laka i genetic predisposition i nei tih i hriat chuan i hlauhawmna tihtlem thei nunphung i hmang thei ang. | Results chiang lo: Scientist-te chuan gene tam tak chanvo an la hrethiam lo a, i test-naah hian awmzia hriat loh inthlak danglamna a hmu thei a ni. |
| Therapies bik: Cancer ang chi natna enkawlna atana hmanraw tangkai ber, mimal atana hman tur thlan chhuah tura tanpui. | Stress: Damdawi theih loh natna hlauhawm tak i nei tih i hriat chuan lungkhamna nasa tak emaw, lungngaihna emaw a thlen thei a ni. |
| Undiagnosed disease diagnosis: Hun rei tak chhunga hriat loh damdawi lam harsatna awm chhan chiang tak hmuh theihna. | Privacy chungchang: I genetic information zawng zawng chu private company kutah dah vek i ngaihtuah tur a ni. Data security chungchang hi i ngaihtuah tur a ni. |
Chutiang test i ngaihtuah a nih chuan, a thu hriatte aṭanga lungkhamna a thlen theih dân pawh i ngaihtuah tûr a ni. Mi ṭhenkhatin an hmalam hun hriat lawk an duh laiin, ṭhenkhat erawh chuan an tuar thei lo mai thei. Tin, i mimal genetic information sang tak chu private company hnena pek chungchang pawh ngaihtuah nawn leh rawh. An data humhalhna policy te ngun takin chhiar la, hrethiam rawh.
Take-Home Thuchah a ni
- Genomic medicine hi gene pakhat chauh chungchang a ni lo va, i taksaa gene zawng zawngte thawhhona a ni zawk .
- Hei hi damdawi lama field thar a ni. Natna hmuh tur awm lo, hriat harsa tak takte hriatchhuahna kawngah theihna nasa tak a nei a, cancer vei te tan pawh mimal damdawi pek theihna a nei bawk.
- Hei hi tun dinhmunah chuan mi zawng zawngin kan neih tur routine test a ni lo. Tunah hian damdawi lam mamawh bik nei tan a tangkai ber a ni.
- He test hian hlawkna a neih theih laiin, stress leh personal data venhimna lamah pawh nghawng tha lo tak a nei thei bawk.
- A pawimawh ber: Hetiang test neih i ngaihtuah a nih chuan nangmah chauhin thutlukna siam suh. I doctor nen inbia hmasa la , a thurawn pawh la hmasa phawt ang che.
💬 Comments (0)
Comment a la awm lo. Hetah hian i comment hi a vawikhatna atan add rawh.
I comment kha add rawh