Mwina mukudziwa kuti Ankylosing Spondylitis (AS) ndi matenda omwe amakhudza moyo wonse, ndipo amafooketsa pang'ono. Mukudziwa momwe zimakhalira zovuta kupirira tsiku lonse ndi ululu wa msana komanso kuuma kwa m'mawa. Koma pali nkhani yabwino. Ngakhale kuti matendawa sangachiritsidwe kwathunthu, titha kuwongolera zizindikiro zake ndi mankhwala oyenera, masewera olimbitsa thupi, komanso moyo wathanzi. Mankhwalawa angathandize kuletsa kapena kuchedwetsa kukula kwa mavuto a msana.
Gawo Loyamba: Mankhwala a NSAID - ochepetsa ululu ndi kutupa
Mukapita kwa dokotala, uwu ndi mtundu woyamba wa mankhwala omwe angayese kukupatsani chifukwa cha vutoli. Timawatcha kuti Nonsteroidal Anti-inflammatory Drugs, kapena (NSAIDs) mwachidule. Ngakhale ena mwa awa angagulidwe pa kauntala ku pharmacy, ena amafunika kuti dokotala awalembe mankhwala.
Mwachidule, mankhwalawa amagwira ntchito poletsa kupanga mankhwala otchedwa prostaglandins m'thupi lathu omwe amayambitsa kutupa. Izi zimachepetsa ululu ndi kutupa kwanu. Kumwa mankhwalawa usiku, makamaka, kungakuthandizeni kugona bwino ndikuchepetsa kuuma kwa msana m'mawa.
Chofunika kwambiri ndikumwa mankhwalawa pa mlingo womwe mwapatsidwa komanso kwa nthawi yomwe mwapatsidwa monga mwalangizidwira ndi dokotala . Musasiye kapena kusintha mlingo momwe mukufunira.
| Mtundu wa mankhwala (NSAID) | Zotsatirapo zake ndi zomwe muyenera kudziwa |
|---|---|
| Mankhwalawa angayambitse kuvutika m'mimba akagwiritsidwa ntchito kwa nthawi yayitali. Mwachitsanzo:
Choncho, dokotala wanu angapereke mankhwala ena (monga mankhwala oletsa asidi) kuti ateteze m'mimba mwanu pamodzi ndi mankhwalawa. Ngati muli ndi mbiri ya matenda a mtima, muyenera kuuza dokotala wanu. Mankhwala ena a NSAID angawonjezere pang'ono chiopsezo cha matenda a mtima kapena sitiroko. |
Gawo lachiwiri: Mankhwala a DMARD - mankhwala ochepetsa matenda a nyamakazi
Nthawi zina mankhwala a NSAID okha sangakhale okwanira kulamulira zizindikiro zanu. Ngati zili choncho, dokotala wanu angakulembereni mtundu wa mankhwala otchedwa (DMARDs) , omwe amatanthauza Mankhwala Oletsa Kupweteka kwa Thupi . Ngakhale dzinalo lingamveke lovuta, zomwe limachita n'zosavuta. Limagwira ntchito pochepetsa kuwonongeka kwa mafupa ndi minofu yanu chifukwa cha kutupa. Izi zimachepetsa kupitirira kwa matendawa.
| Mtundu wa mankhwala (DMARD) | Zinthu zofunika kudziwa makamaka |
|---|---|
| Sulfasalazine | Izi zimatengedwa ngati piritsi. Anthu ena amatha kukhala ndi mutu, kutupa, nseru, komanso zilonda pakamwa. Nthawi zambiri, mafuta am'mafupa amatha kukhudzidwa, choncho dokotala wanu nthawi zambiri amayesa magazi anu akamakupatsirani mankhwalawa. |
| Methotrexate | Izi zimabwera ngati piritsi kapena jakisoni yomwe mungadzipatse nokha. Muyenera kumwa mapiritsi a folic acid ndi izi. Izi ndichifukwa chopewa mavuto monga zilonda pakamwa ndi nseru. Popeza awa ndi mankhwala amphamvu pang'ono, dokotala wanu adzayang'ana magazi anu ndi chiwindi chanu nthawi zonse. Mankhwalawa si oyenera amayi apakati kapena omwe akuyesera kutenga pakati. |
Corticosteroids - mpumulo wachangu wa mafupa opweteka
Izi ndi mtundu wa steroid. Dokotala wanu angakupatseni jakisoni wa steroid, monga ``Prednisone'', mwachindunji m'malo olumikizirana mafupa omwe akuwawa kwambiri komanso otupa. Izi zikuthandizani nthawi yomweyo ku ululu ndi kutupa.
Koma kumbukirani, iyi si njira yochizira yomwe imaperekedwa ku thupi lonse. Komanso, jakisoni iyi singaperekedwe pafupipafupi. Kawirikawiri, dokotala amapereka jakisoni iyi kangapo pachaka, ndi nthawi ya miyezi ingapo.
Biologics - njira yatsopano komanso yamphamvu kwambiri yothandizira
Ngati mankhwala ena sakugwira ntchito kwa inu, dokotala wanu angakuuzeni za mankhwala atsopanowa. Mankhwalawa amatchedwa biologics . Amapangidwa kuchokera ku maselo amoyo. Makamaka, mankhwalawa amaletsa mapuloteni otchedwa cytokines omwe amayambitsa kutupa m'thupi lathu. Uwu ndi mankhwala ofunikira. Awa amabwera ngati jakisoni. Ena mwa iwo mungapereke nokha kunyumba.
Zoletsa za TNF
Izi ndi mtundu wa biologic womwe nthawi zambiri umagwiritsidwa ntchito pofotokoza za AS. TNF imayimira puloteni yotchedwa ``Tumor Necrosis Factor''. Mankhwalawa amachiritsa kutupa kwa msana, mafupa, maso, ndi matumbo. Amathanso kuchepetsa kupita patsogolo kwa AS.
- Adalimumab (Humira)
- Certolizumab pegol (Cimzia)
- Etanercept (Enbrel)
- Golimumab (Simponi)
- Infliximab (Remicade)
Zoletsa za Interleukin (IL-17)
Ngati mankhwala oletsa TNF sagwira ntchito, dokotala wanu angakuyambeni ndi mtundu uwu.
- Ixekizumab (Taltz)
- Sekukinumab (Cosentyx)
Mankhwala a biologic ndi amphamvu kwambiri. Ichi ndichifukwa chake ali ndi zotsatirapo zoyipa zomwe muyenera kuzidziwa. Dokotala wanu adzakufotokozerani zonsezi musanayambe kulandira chithandizo.
| Zoopsa zazikulu ndi zotsatirapo zake za biologics | |
|---|---|
| Kuopsa kwa matenda | Popeza mankhwala amenewa amaletsa chitetezo chamthupi pang'ono, amawonjezera chiopsezo chotenga matenda, makamaka chifuwa chachikulu (TB). Chifukwa chake, ndikofunikira kuyezetsa chifuwa chachikulu musanayambe kumwa mankhwalawa. |
| Zoopsa zina | - Kuwonjezeka pang'ono kwambiri kwa chiopsezo cha khansa ya pakhungu. - Kuwonjezeka kwa chiopsezo cha khansa ya lymphoma mwa ana. - Ngati muli kale ndi matenda otupa m'mimba (IBD), zizindikiro zanu zitha kukulirakulira. |
Ngati simukumva bwino patatha miyezi itatu ya chithandizochi, dokotala wanu adzasankha kusiya kumwa mankhwalawo kapena kukusamutsirani ku mankhwala ena achilengedwe.
Chiyembekezo cha chithandizo chamtsogolo
Asayansi akugwira ntchito yopeza mankhwala atsopano omwe angasinthe AS. Akufufuzanso momwe majini athu amakhudzira matendawa. Kafukufukuyu angapangitse kuti pakhale chithandizo chothandiza kwambiri chomwe chingakuthandizeni mtsogolo.
Uthenga Wopita Nawo Kunyumba
- Matenda a Ankylosing Spondylitis (AS) ndi matenda omwe munthu amakhala nawo kwa moyo wake wonse, koma amatha kuchiritsidwa bwino ndi chithandizo choyenera komanso moyo wabwino.
- Chithandizo nthawi zambiri chimayamba ndi mankhwala a NSAID. Ngati awa sakulamulira vutoli, mankhwala monga DMARD kapena biologics amagwiritsidwa ntchito.
- Khulupirirani dokotala wanu. Tsatirani malangizo ake molondola. Pitani kuzipatala pa nthawi yake ndipo kayezetseni.
- Musasiye kumwa mankhwala anu kapena kusintha mlingo nokha. Ngati muli ndi nkhawa iliyonse, lankhulani ndi dokotala wanu.
- Kuphatikiza pa mankhwala, kuchita masewera olimbitsa thupi moyenera komanso kudya zakudya zabwino ndi zinthu ziwiri zofunika kwambiri kuti muchepetse matendawa.
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