Kodi mphumu yanu ndi yovuta kuilamulira? Tiyeni tiphunzire za katemera wa Xolair wa mphumu yoopsa.

Anthu ambiri omwe ali ndi mphumu amatha kuwongolera zizindikiro zawo ndi inhaler ya tsiku ndi tsiku. Koma kwa ena, inhaler iyi yokha sikokwanira. Kodi ndi momwe zilili ndi inu? Mukakhala ndi mphumu yoopsa, ndipo mankhwala anu wamba sakuthandiza, ikhoza kukhala mtolo waukulu, eti? Koma musadandaule. Posachedwapa, mankhwala atsopano ayambitsidwa kuti athetse matenda oopsa a mphumu. Awa si ma inhaler, koma jakisoni. Limodzi mwa mankhwala otere ndi Xolair.

Kodi Xolair imagwira ntchito bwanji? Choyamba, tiyeni timvetse pang'ono za mphumu.

Mwachidule, mphumu ndi matenda osatha omwe amakhudza mapapu athu. Amayambitsa kutupa kwa njira zathu zopumira, machubu omwe amanyamula mpweya kudzera m'mapapu athu. Minofu yozungulira imalimbanso. Kutupa ndi kulimba kumeneku kumapangitsa kuti njira zopumira zikhale zosavuta. Nthawi zina, zimatha kutsekedwa ndi ntchofu.

Anthu omwe ali ndi mphumu amakumana ndi zizindikiro monga kutsokomola, kupuma movutikira, kupuma movutikira, komanso kulimba pachifuwa. Timatcha izi kuti "kuukira kwa mphumu." Pali zifukwa zosiyanasiyana, kapena "zimayambitsa," zomwe zingayambitse kuukira.

Chifukwa chachikulu cha mphumu mwa anthu ena ndi ziwengo . Chitetezo cha mthupi cha anthuwa chimayankha mopitirira muyeso ku zinthu zina. Timatcha zinthuzi kuti ziwengo . Kwa anthuwa, ziwengo izi zikalowa m'thupi, mphumu imatha kuukira.

Cholinga chachikulu chochiza mphumu ndi kuchepetsa kutupa ndi kupsinjika kwa mapapo. Izi zimapangitsa kuti kupuma kukhale kosavuta komanso kuchepetsa kuchuluka kwa matenda a mphumu.

Mankhwala a Xolair ali ndi chogwiritsira ntchito cha omalizumab . Amagwira ntchito potseka chinthu chotchedwa Immunoglobulin E (IgE) m'thupi mwathu. Pamene chinthu choyambitsa matenda chalowa m'thupi, thupi lathu limapanga IgE yambiri. Pamene IgE iyi yatsekedwa m'thupi la munthu amene ali ndi mphumu ya allergic, thupi limayamba kuyankha zinthu zoyambitsa matenda komanso kutupa m'mapapo.

Kodi pali aliyense amene ali ndi mphumu amene angagwiritse ntchito mankhwalawa?

Ayi. Anthu ambiri omwe ali ndi mphumu amatha kuchepetsa zizindikiro zawo pogwiritsa ntchito mankhwala opumira nthawi zonse. Nthawi zina, vutoli limathetsedwa bwino ndi mankhwala omwa.

Xolair imaperekedwa kwa anthu omwe ali ndi mphumu yayikulu okha omwe sangathe kuwongolera zizindikiro zawo ngakhale atagwiritsa ntchito mlingo wapamwamba kwambiri wa inhaler yawo. Komanso, kuti mugwiritse ntchito mankhwalawa, muyenera kuti mwayesedwa ndi dokotala ndipo mwatsimikiziridwa kuti muli ndi vuto la aeroallergen yosatha, monga dander ya nyama kapena fumbi.

Kodi munadziwa bwanji kuti mankhwalawa ndi othandiza?

Kafukufuku wambiri wa zachipatala wachitika kuti adziwe ngati Xolair ndi yotetezeka komanso yothandiza. Izi zachitika mwa akuluakulu ndi ana.

Onse omwe adachita nawo kafukufukuyu anali ndi vuto lopuma ngakhale atagwiritsa ntchito mankhwala opumira omwe anali ndi mlingo wokwanira. Anatsimikiziridwanso kuti ali ndi ziwengo, monga fumbi.

Mwachidule, kafukufukuyu anachitidwa motere:

• Gulu limodzi linapatsidwa katemera wa Xolair. Gulu lina linapatsidwa katemera wongopeka, wotchedwa placebo . Koma palibe amene ankadziwa zomwe ankalandira.
• Aliyense anauzidwa kuti apitirize kugwiritsa ntchito mankhwala awo opumira.
• Patatha miyezi ingapo, mlingo wa aliyense wa corticosteroid inhaler unachepetsedwa pang'onopang'ono.
• Kenako anayang'ana ngati omwe adatenga Xolair adapumula kwambiri kuposa omwe adatenga placebo.

Kodi ubwino wa kafukufukuyu ndi wotani?

Mapindu awiri akuluakulu anali oonekera bwino.

1. Kuchepa kwa matenda oopsa a mphumu: Gulu la Xolair linali ndi chiwerengero chochepa kwambiri cha matenda oopsa a mphumu poyerekeza ndi gulu la placebo. Izi zinapitirizidwa ngakhale mlingo wa inhaler utachepetsedwa.

2. Kutha kuchepetsa mlingo wa mankhwala ophera inhaler: Pafupifupi 75% ya anthu omwe adamwa Xolair adachepetsa mlingo wawo wa tsiku ndi tsiku wa mankhwala ophera inhaler a corticosteroid ndi theka, poyerekeza ndi 50% yokha ya omwe adamwa placebo.

Kodi katemera wa Xolair amagwiritsidwa ntchito bwanji?

Xolair ndi jakisoni woperekedwa pansi pa khungu . Amaperekedwa milungu iwiri kapena inayi iliyonse. Dokotala wanu adzasankha kangati komwe muyenera kulandira jakisoni, kutengera zaka zanu, kulemera kwanu, ndi kuchuluka kwa IgE m'magazi anu. Jakisoniyo angaperekedwe m'ntchafu, m'mimba, kapena kumbuyo kwa mkono wapamwamba.

Chofunika kwambiri ndichakuti mlingo woyamba wa katemera nthawi zonse uperekedwe kuchipatala kapena kuchipatala. Izi ndi kuonetsetsa ngati muli ndi vuto lililonse la ziwengo. Pambuyo pake, ngati mwakwaniritsa zofunikira zina, dokotala wanu angakuloleni kudzibaya jakisoni kunyumba.

Pali njira ziwiri zopezera mankhwalawa. Chimodzi ndi chipangizo chonga cholembera chotchedwa autoinjector . Izi zimakupatsani mwayi wolowetsa katemera mosavuta popanda kugwiritsa ntchito syringe kapena singano. China ndi syringe yomwe imabwera ndi singano monga mwachizolowezi. Ngati muli ndi vuto la latex, musaiwale kuuza dokotala wanu za izi. Chifukwa ma syringe ena akhoza kukhala ndi latex.

Kodi zimatenga nthawi yayitali bwanji kuti munthu apeze mpumulo ku izi?

Ngati katemera wa Xolair ndi woyenera kwa inu, muyenera kuyamba kumva bwino pakatha milungu ingapo . Pakapita nthawi, mudzakhala ndi mphumu yochepa. Muthanso kuchepetsa mlingo wa mankhwala anu oletsa kutupa otchedwa corticosteroid inhaler.

Ngati simukumva kusintha kulikonse patatha miyezi ingapo, dziwitsani dokotala wanu za zimenezo.

Zotsatirapo zake ndi momwe mungathanirane nazo?

Anthu omwe amatenga Xolair akhoza kukhala ndi mwayi wopeza matenda opatsirana m'mapapo (pakhosi, chimfine). Njira yabwino yopewera izi ndi kusamba m'manja pafupipafupi, kukhala aukhondo, komanso kupewa anthu odwala. Ndipo pezani jakisoni wa chimfine chaka chilichonse.

Nthawi zambiri, anthu ena amakhala ndi vuto lalikulu la ziwengo, lotchedwa anaphylaxis , akamaliza kumwa mankhwala oyamba. Ili ndi vuto lalikulu kwambiri. Ndicho chifukwa chake mankhwala anu oyamba amaperekedwa nthawi zonse kuchipatala. Kumeneko, ogwira ntchito zachipatala ophunzitsidwa bwino adzakuyang'anirani ndipo adzakhala okonzeka kukuthandizani nthawi yomweyo ngati pakhala vuto lililonse.

Sikuti izi zokha, komanso zotsatirapo zina zingachitikenso. Ngati muli ndi zizindikiro zilizonse zomwe zikukuvutitsani, lankhulani ndi dokotala wanu.

Kodi pangakhale mavuto ndi mankhwala ena?

Palibe kuyanjana kwakukulu pakati pa Xolair ndi mankhwala ena. Komabe, ndikofunikira kuuza dokotala wanu za mankhwala onse (omwe amalembedwa ndi dokotala kapena omwe amagulitsidwa pamtengo wotsika), mavitamini, mankhwala azitsamba, ndi zowonjezera zomwe mukumwa.