Yintoni i-VLDL (Very-Low-Density Lipoprotein) kwi-cholesterol yakho? Masifumanise ukuba yintoni kanye kanye!

Mhlawumbi ukhe weva nge -cholesterol , akunjalo? Usenokuba ukhe walibona eli gama kwingxelo yakho yegazi. Akukho nto yokoyika xa usiva igama elithi cholesterol. Nangona kunjalo, kukho iintlobo ezahlukeneyo zalo, kwaye kubalulekile ukwazi ngazo. Namhlanje siza kuthetha ngelungu losapho lwe-cholesterol, kwaye yi -VLDL (Very-Low-Density Lipoprotein) . Eli gama lisenokuba litsha kuwe, kodwa ungakhathazeki, masilichaze ngokulula.

Yintoni i-VLDL (Very-Low-Density Lipoprotein), mhlobo?

Ngamafutshane, i-VLDL luhlobo oluthile lwesuntswana elenziwa sisibindi sethu lize likhutshwe liye egazini lethu. Ezi zezeqela leeproteni ezibizwa ngokuba zii-lipoproteins .

Cinga nje, amafutha asegazini lethu, njenge -cholesterol kunye ne -triglycerides , awashukumi egazini ngokwawo. Awanyibiliki emanzini. Ngoko ke, la mafutha adinga isithuthi sokuwathutha aye kwiindawo ezahlukeneyo zomzimba. Eso sithuthi sibizwa ngokuba yi-lipoproteins. Kufana nebhasi!

Umsebenzi ophambili we-VLDL kukuthatha ii-triglycerides kunye ne -cholesterol ethile kwaye uzithuthe ziye kwiindawo apho zifuneka khona emzimbeni. Ngale ndlela, i-VLDL inceda umzimba wethu ukuba ufumane amandla, ugcine amandla, kwaye ulawule uxinzelelo lwegazi. Ngoko ke, zibaluleke kakhulu ekusebenzeni ngokuqhelekileyo kwemizimba yethu.

Nangona kunjalo, nantsi into ekufuneka uyikhumbule: Ukuba ubungakanani be-VLDL egazini buphezulu kakhulu , kunokuba yingozi. Ukuba oko kuyenzeka, umngcipheko wokuba nesifo sentliziyo uyanda.

Yintoni engaphakathi kwezi nxalenye ze-VLDL?

Isuntswana le-VLDL lenziwe ikakhulu ngohlobo lwamafutha olubizwa ngokuba yi -triglycerides . Likwaqulathe i-cholesterol , ii-fatty acids, kunye nohlobo oluthile lweproteni olubizwa ngokuba yi -apolipoprotein B (apoB) . Uphando lufumanise ukuba amanqanaba aphezulu ale apoB egazini anxulunyaniswa nomngcipheko okhulayo wesifo sentliziyo.

Enyanisweni, zonke ii-lipoprotein zenziwe ngamafutha kunye neeproteni. Nangona kunjalo, ubungakanani kunye neentlobo zezi mafutha kunye neeproteni ziyahluka ukusuka kwi-lipoprotein enye ukuya kwenye. Ngenxa yokuba ii-VLDL ziphezulu kakhulu kwi -triglycerides , oogqirha ngamanye amaxesha bazibiza ngokuba "zii-lipoproteins ezityebileyo kwi-triglyceride."

Ngaba i-VLDL kunye ne-VLDL cholesterol zizinto ezimbini ezahlukeneyo?

Oku kungabonakala kudida kancinci, kodwa kulula ukukuqonda. Amaxesha amaninzi, amagama athi "VLDL" kunye "VLDL cholesterol" asetyenziswa ngokutshintshana. Nangona kunjalo, kukho umahluko omncinci phakathi kwezi zimbini ezibalulekileyo ukwazi.

• I-VLDL ibhekisa kwisuntswana le-lipoprotein esilikhankanyileyo ngaphambili. Oko kukuthi, "isithuthi" okanye "ibhasi" eyenziwa sisibindi kwaye ithwala amafutha kunye neeproteni egazini.
• I-cholesterol ye-VLDL ibhekisa kubakhweli be-cholesterol kwibhasi ye-VLDL. Oko kukuthi, ubungakanani be-cholesterol ehanjiswa kulo lonke igazi yi-VLDL particle.

Ezinye iintlobo zee-lipoprotein, ezifana ne -LDL (Low-Density Lipoproteins) kunye ne-HDL (High-Density Lipoproteins) , ziyafana nezinye iintlobo ze-cholesterol. Ngayinye inemilinganiselo eyahlukeneyo kunye neentlobo zamafutha kunye neeproteni. Yiyo loo nto sithetha nange-LDL cholesterol kunye ne-HDL cholesterol.

Ngoko ke, ngaba i-VLDL luhlobo lwe-cholesterol "embi"?

Ewe, ngamafutshane, ukuba ubungakanani be-VLDL cholesterol egazini buphezulu kunokuba kuyimfuneko, kunokuthiwa "bubi". Umzimba wethu udinga ubungakanani obuthile be-VLDL kwiimfuno zawo. Nangona kunjalo, ukuba inqanaba le-VLDL liyakhula, kwandisa umngcipheko we-atherosclerosis , oko kukuthi, ukwakheka kwamafutha (i-plaque) ngaphakathi kwemithambo yegazi (imithambo yegazi). Le yimbangela yezifo ezininzi zentliziyo.

I-VLDL inegalelo njani kwi-atherosclerosis?

Xa isibindi sethu sivelisa i-VLDL engaphezulu kuneemfuno zomzimba wethu, umzimba uyayicola i-VLDL eyongezelelweyo. Ngale ndlela, i-VLDL iqala iguqulwe ibe yi -IDL (Intermediate-Density Lipoproteins) ize emva koko ibe yi-LDL (Low-Density Lipoproteins) . Ezi IDL kunye ne-LDL ziintlobo zee- lipoproteins ezidingwa ngumzimba.

Kodwa ingxaki kukuba, ukuba le LDL iba ngaphezulu koko umzimba ukudingayo, inokuqokelelana. Xa kukho i-LDL engaphezulu egazini, inokunamathela eludongeni lwemithambo yegazi, apho iidipozithi zamafutha (i-plaque) ziqala ukwakheka khona. Njengoko ezi dipozithi zamafutha zikhula kancinci kancinci, ziyayicutha imithambo yegazi kwaye zithintele ukuhamba kwegazi.

Uphando lufumanise ukuba ukunyuka kwamanqanaba e-VLDL kunye nokunyuka kwamanqanaba e-LDL kuyingozi ngakumbi kunokunyuka kwamanqanaba omabini kuphela.

Akuphelelanga apho, xa i-VLDL iqhekeka kwaye i-LDL yenziwe, ezinye " iinxalenye eziseleyo" zishiywa egazini. Ezi nxalenye ziseleyo zikwanayo ne-cholesterol eninzi. Ngenxa yokuba zincinci ngobukhulu, zinokubhajwa lula eludongeni lwemithambo yegazi zize zibangele i-atherosclerosis (Iyakhawulezisa inkqubo ye-atherosclerosis.

I-atherosclerosis yimeko eyingozi kuba inciphisa imithambo yakho yegazi, yandisa umngcipheko wakho wokufumana izifo ezahlukeneyo zentliziyo. Nazi imizekelo embalwa:

• Isifo semithambo yegazi ye-Coronary ( izifo zemithambo yegazi ehambisa igazi entliziyweni)
• Isifo semithambo yegazi ( izifo ezikwimithambo yegazi ezihambisa igazi engqondweni, ezinokukhokelela kwiimeko ezifana nestroke)
• Isifo semithambo yegazi ejikeleze imithambo yegazi ( izifo zemithambo yegazi ezihambisa igazi ezingalweni nasemilenzeni)
• I-Aortic aneurysm (ukuba buthathaka nokudumba kwe-aorta, umthambo wegazi oyintloko womzimba)

Yeyiphi eyona imbi, i-LDL okanye i-VLDL?

Enyanisweni, zombini i-cholesterol ye-LDL kunye ne-cholesterol ye-VLDL zinegalelo ekwandeni kwamafutha (i-plaque) kwimithambo yethu. Ngoko ke, kunzima ukuthi enye "imbi" kunenye. Zombini ziyafana ne-atherogenic, oko kuthetha ukuba zinegalelo kwinkqubo yokufakwa kwamafutha kwimithambo. Ngoko ke kubalulekile ukuba uzazi zombini.

Ilinganiswa njani i-cholesterol ye-VLDL?

Oogqirha balinganisa amanqanaba e-cholesterol yakho ye-VLDL ngovavanyo lwegazi olubizwa ngokuba yi-lipid panel . Olu luvavanyo lwegazi oluqhelekileyo.

Le panel ye-lipid ibonisa inqanaba elipheleleyo le-cholesterol egazini lakho. Ayipheleli apho, kodwa ikwabonisa amanqanaba eentlobo ezahlukeneyo ze-cholesterol ezibizwa ngokuba yi-HDL (i-cholesterol elungileyo), i-LDL (i-cholesterol embi), kunye ne-VLDL ngokwahlukeneyo. Kwakhona, olu vavanyo lunokukuxelela inqanaba le -triglycerides egazini lakho. Khumbula, sithe i-VLDL ine-triglycerides eninzi.

Ngokwesiqhelo, iilabhoratri azilinganisi amanqanaba akho e-VLDL ngokuthe ngqo. Endaweni yoko, zisebenzisa amanqanaba akho e-triglycerides ukubala amanqanaba akho e-VLDL ngefomula yemathematika. Ngokubanzi, ii-triglycerides zakho ziphindwe kahlanu amanqanaba akho e-VLDL.

Nangona kunjalo, ukuba unesifo esibi esibizwa ngokuba yi -hypertriglyceridemia , apho amanqanaba akho e-triglyceride ephezulu kakhulu, loo mathematika isenokungachaneki kangako. Kwimeko enjalo, ugqirha wakho unokusebenzisa indlela eyahlukileyo yokuqikelela amanqanaba akho e-VLDL.

Ingakanani inqanaba eliqhelekileyo le-cholesterol ye-VLDL?

Inqanaba eliqhelekileyo, okanye elisempilweni, le-VLDL lingaphantsi kwama-30 milligrams nge-deciliter yegazi ( < 30 mg/dL ). Ukuba inqanaba le-cholesterol yakho ye-VLDL liyi- 30 mg/dL okanye ngaphezulu , lithathwa njengeliphezulu.

Kwenzeka ntoni ukuba i-VLDL cholesterol iphakanyisiwe?

Eyona nto iphambili kukuba amanqanaba aphezulu e-VLDL cholesterol anyusa umngcipheko wesifo sentliziyo .

Nangona kunjalo, ngenxa yokuba amanqanaba e-VLDL abalwa kusetyenziswa ifomula yemathematika endaweni yokulinganiswa ngokuthe ngqo, kwaye ngenxa yokuba i-VLDL ayilo njongo iphambili yoogqirha xa bekunyanga, ugqirha wakho usenokungathethi nawe ngqo malunga nenqanaba lakho le-VLDL. Endaweni yoko, uya kugxila ngakumbi kwamanye amaxabiso, njengenqanaba lakho le-LDL kunye ne-triglycerides , kuba lawo ngamaxabiso ajoliswe kakhulu kunyango.

Abantu abaninzi abanamanqanaba aphezulu e-cholesterol ye-VLDL banokuba nenye okanye ngaphezulu kwezi meko zilandelayo ngexesha elinye:

• Amanqanaba aphezulu e-triglyceride (i-Hypertriglyceridemia)
• Amanqanaba e-cholesterol e-LDL anyukileyo
• Ukwanda kwenqanaba le-cholesterol iyonke (i-Hyperlipidemia)

Iindaba ezimnandi zezokuba, kukho izinto ezininzi onokuzenza ukunciphisa olu hlobo lwamafutha (lipids) egazini lakho:

• Ukulandela ukutya okunempilo kwentliziyo , njengokutya kwaseMeditera , okugxininisa kwimifuno, iziqhamo, iimbotyi, iinkozo ezipheleleyo, intlanzi, kunye namafutha anempilo afana neoyile yomnquma.
• Zilolonge rhoqo . Nangona kunjalo, kubaluleke kakhulu ukuthetha nogqirha wakho kwaye ufumane iingcebiso ngaphambi kokuba uqale inkqubo entsha yokuzilolonga.
• Gcina ubunzima obusempilweni obufanela ubude bakho kunye nohlobo lomzimba wakho.
• Ukuba ugqirha wakho uyayicebisa, thatha amayeza okunciphisa i-cholesterol afana nee -statins .

Kwezinye iimeko, usenokuba nesifo esingabonakaliyo esinokubangela ukuba ii-triglycerides zakho zinyuke, nto leyo enokubangela ukuba amanqanaba akho e-cholesterol e-VLDL anyuke. Kwakhona, amanye amayeza owasebenzisayo anokubangela ukuba zombini ezi zinto zinyuke. Ke ngoko, kubalulekile ukuthetha ngokukhululekileyo nogqirha wakho malunga nokuba yintoni ebangela ukuba amanqanaba akho e-cholesterol e-VLDL anyuke kunye nento onokuyenza ukuyilungisa.

Kubomi bakho bemihla ngemihla, mhlawumbi awucingi kakhulu ngezi lipoproteins ezihambahamba egazini lakho. Kodwa ukuba ugqirha ukuxelela ukuba amanqanaba akho e-cholesterol aphezulu, ungaqala ukucinga ngezi nxalenye kunye nendlela ezichaphazela ngayo impilo yakho.

Okokugqibela, into ekufuneka uyikhumbule...

Eyona nto ibalulekileyo kukuba ungoyiki xa ufumanisa ukuba amazinga akho e-cholesterol aphezulu. Le yimeko enokulawulwa rhoqo ngokutshintsha indlela ophila ngayo kwaye, ukuba kuyimfuneko, amayeza.

Thetha nogqirha wakho malunga nokuba inqanaba lakho le-VLDL lithetha ukuthini kuwe kunye nento onokuyenza ukuze uliphucule. Uza kukunika icebiso elihle kakhulu. Ukuze uhlale usempilweni, kungcono ukuba uqaphele ezi zinto kwaye ulandele icebiso likagqirha wakho!

I- Cholesterol, i-VLDL, iiTriglycerides, Isifo sentliziyo, iLipid Panel, i-Atherosclerosis, iMpilo