Kunzima ukuchaza uloyiko, ixhala, kunye nokungaqiniseki okuza nokuxilongwa komhlaza webele. Kodwa eyona nto ibalulekileyo ekufuneka uyazi kukuba unyango lomhlaza luhambe phambili kakhulu namhlanje. Namhlanje, siza kuthetha ngonyango olutsha noluphambili. Lubizwa ngokuba yiDatroway. Makhe sibone ukuba yintoni iDatroway kwaye inokukunceda na.
Luhlobo luni lonyango oluyiDatroway? Lusebenza njani?
Ngamafutshane, iDatroway lunyango olujoliswe kulo oluphuhliswe kusetyenziswa ubuchwepheshe obuphambili. Kwizonyango, oku sikubiza ngokuba yiAntibody Drug Conjugate (ADC) . Cinga ngayo njengenkonzo ekhethekileyo yokuhambisa. Le molekyuli yeziyobisi yenziwe ngamacandelo amathathu aphambili.
1. I-Antibody: Le "yi-address finder" ye-courier yethu. Ifumana iproteni ethile (iproteni ebizwa ngokuba yiTrop-2) kumphezulu weeseli zomhlaza ize inamathele kuyo. Umsebenzi wayo kukubulala nokubamba iiseli zomhlaza kuphela, ngaphandle kokulimaza iiseli eziphilileyo.
2. Amayeza okulwa nomhlaza ( i-chemotherapy ): Le "yiphakheji" ekwi-courier. Le yiyeza elitshabalalisa iiseli zomhlaza.
3. Ikhonkco: Le nxalenye idibanisa i-antibody kunye neyeza lokulwa nomhlaza. Ezi zimbini zibotshelelwa kunye xa zihamba egazini, zize zahlulwe emva kokungena kwiseli yomhlaza.
Ngoko ke, xa iyeza leDatroway lingena emzimbeni, i-antibody ekuyo ifumana ngqo iiseli zomhlaza ize izincamathele. Emva koko, loo linker iyaphuka, ikhuphe iyeza lokulwa nomhlaza ngqo kwiseli yomhlaza. Ngale ndlela, iseli yomhlaza iyatshatyalaliswa ngaphakathi. Eyona nzuzo inkulu yale ndlela kukuba umonakalo kwiiseli eziphilileyo uncitshiswa kakhulu.
Inikwa njani unyango lweDatroway?
I-Datroway lunyango olunikwa esibhedlele, eklinikhi, okanye kwiziko lonyango phantsi kweliso likagqirha wakho. Lunikwa njengesicombululo setyuwa ngemithambo yegazi (i-intravenous - IV infusion ) .
- Umlinganiselo: Umlinganiselo wamayeza owanikwayo uxhomekeka kubunzima bomzimba wakho.
- Ishedyuli: Olu nyango ludla ngokwenziwa rhoqo emva kweeveki ezintathu . Ugqirha wakho uya kugqiba ukuba ufuna iiseshoni ezingaphi.
- Ukulungiselela kwangaphambili: Ngaphambi kokuba unikwe i-saline, uza kunikwa amanye amayeza okuthintela isicaphucaphu, ukuhlanza, kunye nazo naziphi na iimpembelelo ze-allergy ezinokubakho ngenxa ye-saline.
- Ixesha lonyango:Iseshoni yokuqala yonyango ithatha malunga nemizuzu engama-90. Ukuba awufumani ziphumo zimbi zibalulekileyo okokuqala, unyango olulandelayo lunokunikwa kwimizuzu engama-30 kuphela.
- Ukuqwalaselwa: Emva konyango lokuqala olubini, uza kujongwa ngabasebenzi bezonyango ubuncinane iyure enye. Ukuba akukho ngxaki, uza kujongwa malunga nemizuzu engama-30 kwiiseshoni ezilandelayo uze uvunyelwe ukuba uye ekhaya.
Ndingazi njani ukuba olu nyango lufanelekile kum?
I-Datroway ayilonyango lwazo zonke iintlobo zomhlaza webele . Ugqirha wakho uza kucebisa olu nyango kuphela ukuba umhlaza wakho uhlangabezana nezi mfuno zilandelayo:
- Umhlaza kufuneka ube ne-hormone receptor-positive kwaye ube ne-HER2-negative .
- Xa umhlaza ungenakususwa ngokupheleleyo ngotyando (`olungasuswayo`) okanye usasazeke kwamanye amalungu omzimba (`olusasazekayo`).
Eyona nto ibalulekileyo kukuba ukuze ufanelekele olu nyango, kufuneka ukuba sele ufumene unyango olusekelwe kwi-endocrine kunye nolunye unyango lwe-chemotherapy.
Ngoko ke, isigqibo esifanelekileyo malunga nokuba olu nyango lukulungele na sithathwa ngugqirha wakho we-oncologist onyangayo . Uza kuhlola zonke iirekhodi zakho zonyango aze enze esi sigqibo.
Iziphumo ebezingalindelekanga kunye nendlela yokuzilawula?
Njengalo naluphi na unyango lomhlaza, iDatroway inokubangela ezinye iziphumo ebezingalindelekanga. Kodwa iindaba ezimnandi zezokuba kukho iindlela zokulawula uninzi lwazo. Makhe sijonge iziphumo ebezingalindelekanga eziphambili kunye nento onokuyenza ngazo.
| Imiphumela | Indlela yokulawula |
|---|---|
| Iingxaki zamehlo (Amehlo omileyo, ububomvu, iintlungu, ukubona okufipheleyo) | Sebenzisa amathontsi amehlo aqatywayo acetyiswe ngugqirha wakho ubuncinane kane ngemini. Kuphephe ukunxiba iilensi zokunxibelelana ngexesha lonyango. Xelela ugqirha wakho ngoko nangoko ukuba ubona naluphi na utshintsho okanye ukungakhululeki emehlweni akho. Kusenokwenzeka ukuba uthunyelwe kwingcali yamehlo. |
| Izilonda zomlomo | Gcina iqhekeza lomkhenkce okanye amanzi amancinci omkhenkce emlonyeni wakho ngelixa unika isisombululo setyuwa. Sebenzisa isicoci somlomo esikhethekileyo esichazwe ngugqirha wakho njengoko kuyalelwe. Ukuba kukho naziphi na izilonda zomlomo ezikhulayo okanye eziya ziba mandundu, yazisa ugqirha wakho ngoko nangoko. |
| Isicaphucaphu nokuhlanza | Sela amayeza okulwa nesicaphucaphu owanikwe ngugqirha wakho ngexesha elifanelekileyo, ngaphambi nasemva konyango. |
Ezi zezona ziphumo zixhaphakileyo. Ukuba ufumana naluphi na olunye uvakalelo olungathandekiyo ukongeza kwezi, ungaze woyike ukuthetha nogqirha wakho ngaloo nto.
Zeziphi izinto ekufuneka ziqwalaselwe ngokukodwa?
Xa usebenzisa unyango lweDatroway, kukho izinto ezimbalwa ekufuneka uziqwalasele ngokukodwa.
Iingxaki ezinxulumene nemiphunga
Kunqabile kakhulu, abanye abantu banokuba nokuvuvukala kwemiphunga (`Interstitial Lung Disease` okanye `Pneumonitis`) ngenxa yolu nyango. Ngoko ke, ukuba ufumana iimpawu ezifana nokukhwehlela, ubunzima bokuphefumla, ukuphefumla kancinci, umkhuhlane, okanye ukuqina kwesifuba , musa ukuyityeshela loo nto kwaye wazise ugqirha wakho ngoko nangoko . Ukuba kuyimfuneko, ugqirha uza kuqala unyango lwayo.
Ukukhulelwa kunye nolawulo lokuzalwa
Le yingxaki ebaluleke kakhulu.
- Unyango lweDatroway lunokuba yingozi kusana olungekazalwa. Ngoko ke, uza kuvavanywa ukuze kubonwe ukuba ukhulelwe na ngaphambi kokuba uqale unyango.
- Ukuba ungumfazi onokukwazi ukuzala, kufuneka usebenzise uhlobo lokulawula ukuzala olusebenza kakuhle ngexesha lonyango kwaye kangangeenyanga ezisi-7 emva kokuthatha idosi yokugqibela .
- Ukuba uyindoda kwaye iqabane lakho liyakwazi ukukhulelwa, kufuneka usebenzise ucwangciso lokuzala olusebenzayo ngexesha lonyango kwaye kangangeenyanga ezi-4 emva komthamo wokugqibela .
Ukuba unemibuzo malunga noku, ungathandabuzi ukuthetha nogqirha wakho.
Umyalezo Wokuya Ekhaya
- I-Datroway lunyango olujoliswe kulo noluphambili kwiintlobo ezithile zomhlaza webele. Ifana "nomjukujelwa okhokelwayo" ofuna kwaye utshabalalise iiseli zomhlaza.
- Olu nyango alufanelekanga kuye wonke umntu. Ugqirha wakho wezifo zomhlaza uza kugqiba ukuba lukulungele na.
- Unyango lunikwa njengesicombululo setyuwa ngomthambo, kanye kwiiveki ezintathu.
- Iziphumo ebezingalindelekanga ezifana neengxaki zamehlo, izilonda zomlomo, kunye nokucaphuka zinokubakho. Kodwa ezi zinokulawulwa. Xelela ugqirha wakho ngoko nangoko malunga nokungonwabi.
- Ukuba ufumana iimpawu ezifana nobunzima bokuphefumla, musa ukuzityeshela. Funa ingcebiso kagqirha ngoko nangoko.
- Kubalulekile ukuphepha ukukhulelwa ngexesha lonyango kwaye emva kwexesha elithile.
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