Xa ufunyaniswe ukuba unomhlaza webele, ugqirha wakho uya kwenza uvavanyo oluninzi ukuze afunde ngakumbi ngeeseli zomhlaza. Oku kudla ngokwenziwa ngokuthatha iqhekeza lethishu yomhlaza ngotyando okanye nge-biopsy. Olunye lovavanyo kukubona ukuba iiseli zomhlaza zine- 'hormone receptors ' na. Cinga ngezi receptors 'njengezitshixo' ezincinci kumphezulu weeseli. Xa 'izitshixo' ezibizwa ngokuba zii-hormones zingena kwezi tshixo, iiseli zifumana umyalezo wokuba zikhule.
Iprogesterone yihormone eveliswa ngokwendalo emizimbeni yethu. Ibaluleke kakhulu kwizinto ezifana nokufikisa, ukuya exesheni, kunye nokukhulelwa kwabasetyhini. Ezinye iiseli zomhlaza webele zine-receptors kumphezulu wazo ezinokubophelela kule hormone. Olu hlobo lomhlaza lubizwa ngokuba yi-progesterone-receptor positive, okanye umhlaza webele we-PR-positive (PR+). Okwenzekayo kweli tyala kukuba i-progesterone yehormone iza ize ibophelele kwiiseli zomhlaza kwaye izincede zikhule ngakumbi. Ke, unyango loku luzama ukumisa le nkqubo ye-hormone.
Enye ihomoni esebenza ngendlela efanayo yi-estrogen. Ukuba iiseli zomhlaza zine-estrogen receptors, ibizwa ngokuba yi-estrogen-receptor positive, okanye umhlaza we-ER-positive (ER+).
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Ngubani osengozini enkulu yokuba nale meko?
Ukuba iiseli zakho zomhlaza zi-PR-positive, ER-positive, okanye zombini, ngokuqhelekileyo zibizwa ngokuba ngumhlaza webele we-hormone-receptor positive (HR+). Ngethamsanqa, malunga ne-7 kwi-10 kuphela yomhlaza webele ofunyenweyo yiyo olu hlobo. Nangona olu hlobo lomhlaza lunokukhula nangaliphi na ixesha, luqheleke kakhulu kubafazi abaye badlula kwixesha lokuya exesheni.
Ngokubanzi, izinto ezifanayo ezichaphazela umhlaza webele zikwachaphazela nomhlaza one-HR-positive. Makhe sijonge ukuba zeziphi.
| Into enobungozi | Kalula nje... |
|---|---|
| Ukuba ngumfazi | Abafazi basengozini enkulu xa kuthelekiswa namadoda. |
| Ukwaluphala | Umngcipheko uyanda njengoko iminyaka ikhula. |
| Ukungaqhelekanga kwiiseli zebele | Ukuba ngaphambili ubunokukhula okungaqhelekanga kweeseli emabeleni (umz. i-LCIS ). |
| Imbali yosapho | Ukuba ilungu losapho elisondeleyo liye laba nomhlaza webele. |
| Ukufikisa kwasekuqaleni | Ukuya exesheni kuqala ngaphambi kokuba umntu abe neminyaka eli-12 ubudala. |
| Ukuba nabantwana emva kwexesha | Ukuba nomntwana wakho wokuqala emva kweminyaka engama-35 okanye ukungakhulelwa. |
| Ukuya exesheni emva kwexesha | Ukuya exesheni emva kweminyaka engama-55. |
| Ukuthatha unyango lwehomoni | Ukuthatha unyango lokutshintshwa kweehomoni emva kokuya exesheni. |
Zithini iimpawu?
Uninzi lwexesha, uninzi lwabasetyhini alunazo iimpawu xa befunyaniswa ukuba banomhlaza webele. Endaweni yoko, ufunyanwa ngengozi ngexesha le-mammogram eqhelekileyo.
Iimpawu zomhlaza webele one-HR-positive ziyafana nezezinye iintlobo zomhlaza webele . Nazi ezinye zezona mpawu zixhaphakileyo.
| Uphawu | Lumka oku. |
|---|---|
| Iqhuma elitsha esifubeni | Nasiphi na iqhuma elitsha onokuliva, nokuba alibuhlungu. |
| Ukudumba esifubeni | Ukudumba kwebele lonke okanye inxalenye yalo. |
| Intlungu yebele okanye ingono | Intlungu engaqhelekanga, engapheliyo. |
| Utshintsho lolusu | Ulusu olutshonileyo, ukubonakala kwexolo eli-orenji, ukuqina kwesikhumba, ukuba bomvu, okanye ulusu olomileyo nolunamaxolo. |
| Utshintsho lweengono | Ingono iba yimbobo okanye kuphume ulwelo. |
| Ii-lymph nodes ezivuvukileyo | Amaqhuma asekhwapheni okanye entanyeni anokubanjwa esandleni. |
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Check Availability →Isetyenziswa njani unyango lwe-hormone?
Xa usenza isicwangciso sakho sonyango, ugqirha wakho ngokuqinisekileyo uya kuqwalasela imeko yehomoni yomhlaza wakho. Unyango lwehomoni lolona nyango luphambili nolubaluleke kakhulu lomhlaza one-PR. Injongo kukuthintela iiseli zomhlaza ekusebenziseni iihomoni ukukhula.
Ngamafutshane, unyango lweehomoni luthintela ukubonelelwa 'kokutya' (iihomoni) ezifunekayo ngumhlaza.
Oku kungenziwa ngeendlela ezimbini eziphambili:
- Ukususwa kwamaqanda ngotyando: Oku kunciphisa ukuveliswa kwamahomoni emzimbeni.
- Iipilisi okanye iinaliti zonyango lweehomoni: La mayeza athintela umzimba ekuveliseni iihomoni, okanye athintele ii-receptors (ukutshixa) kwiiseli zomhlaza, ezithintela ekubophelekeni kwiihomoni (izitshixo).
Uhlobo lonyango lweehomoni olufumanayo luya kuxhomekeka ekubeni ukhe wafikelela kwixesha lokuphela kwexesesha lokukhulelwa. Olu nyango lungasetyenziswa nakweyiphi na inqanaba lomhlaza. Ngokuxhomekeke kwinqanaba lomhlaza, unyango lweehomoni lunikwa kunye nolunye unyango, olufana notyando okanye i-chemotherapy.
Ziziphi ezinye iindlela zonyango?
Ukongeza kunyango lweehomoni, unganikwa enye okanye ezingaphezulu kwezi zilandelayo zomhlaza webele one-PR-positive.
- Utyando: Utyando lokususa iiseli zomhlaza. Umzekelo, ukususa iqhuma kuphela (Lumpectomy) okanye ukususa lonke ibele (Mastectomy).
- I-Chemotherapy: Amayeza anamandla anikezelwa ukutshabalalisa iiseli zomhlaza.
- Unyango lwemitha : Isebenzisa imitha enamandla aphezulu ukutshabalalisa naziphi na iiseli zomhlaza eziseleyo.
- Unyango Olujoliswe Kulo: Amayeza ajolise kwiiproteni ezithile ezinceda iiseli zomhlaza zikhule. Ezi zinokunyusa ukusebenza kakuhle konyango lweehomoni.
Ithini ingqikelelo?
Nazi iindaba ezimnandi kuwe. Umhlaza one-hormone-receptor-positive (HR+) udla ngokukhula kancinci kune-hormone-receptor-negative (HR-Negative). Kwakhona, unethuba elihle kunyango kuba lunokuthintela ukusebenza kwee-hormone kwaye luyekise umhlaza ukuba ungakhuli. Nangona kunjalo, njengakuyo nayiphi na i-cancer, unyango lwexesha elizayo luxhomekeke ekubeni lufunyaniswa kwangethuba kangakanani.
Kodwa kukho into ekufuneka uyikhumbule. Nangona unyango lweehomoni lunokulawula ukukhula nokusasazeka komhlaza, ngamanye amaxesha lunokwenzeka emva kweminyaka emininzi unyango. Yiyo loo nto oogqirha ngamanye amaxesha benika unyango lweehomoni ixesha elide, ngamanye amaxesha iminyaka emi-5 okanye eli-10.
Kungoko ke, kubaluleke kakhulu ukuthetha ngokukhululekileyo nangokucacileyo nogqirha wakho malunga nemeko ye-hormone receptor yomhlaza wakho kunye nendlela eza kuyichaphazela ngayo isicwangciso sakho sonyango kunye nendlela eya phambili.
Umyalezo Wokuya Ekhaya
- Umhlaza webele we-PR-Positive (PR+) uthetha ukuba iiseli zomhlaza zisebenzisa i-hormone ye-progesterone ukuze zikhule.
- Olu hlobo lomhlaza luxhaphake kakhulu, ingakumbi emva kokuya exesheni.
- Unyango lwehomoni yindlela yonyango esebenzayo kakhulu neyintloko esetyenziselwa oku.
- Ingqikelelo yokuba ezi cancer zikhula kancinci idla ngokuba ntle kuba zikhula kancinci, kodwa unyango lwexesha elide kunye nokuhlolwa rhoqo kwezonyango kuyafuneka ukuze kuthintelwe ukuphinda kuvele ezi cancer.
- Ungaze ungathandabuzi ukuthetha nogqirha wakho ngemeko yakho, unyango, kunye nazo naziphi na izinto ezikuxhalabisayo.
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