Uncedo ekulweni kwakho nomhlaza: Masifunde ngeekhaphu ze-Ixazomib?

Sonke siyazi ukuba ukulwa nomhlaza akuyonto ilula. Kodwa ngokuhambela phambili kwezonyango zanamhlanje, kukho unyango oluninzi oluhle olunokukunceda kule mfazwe. Elinye iyeza elikhethekileyo libizwa ngokuba yi-Ixazomib . Mhlawumbi ugqirha wakho ukunike eli yeza, okanye mhlawumbi umntu omaziyo uyalisebenzisa. Ngoko ke, masithethe ngeenkcukacha ezithe vetshe ngeli yeza, indlela yokulisebenzisa, kunye nento ekufuneka uyilumkele, akunjalo? Oku kuya kuba luncedo kakhulu kuwe.

Lithini eli yeza libizwa ngokuba yi-Ixazomib?

Ngamafutshane, i-Ixazomib liyeza elinceda ekubulaleni iiseli zomhlaza. Lenza oku ngendlela engabonakaliyo. Njengeeseli emzimbeni wethu, iiseli zomhlaza nazo zineeproteni ezizinceda ukuba ziphile kwaye zikhule. Ngoko ke eli yeza lijolise kwiiproteni ezithile kwiiseli zomhlaza kwaye lizithintele ekukhuleni nasekuhlukaneni. Ngamanye amazwi, lixelela iiseli zomhlaza, "Musa ukukhula, musa ukwahlukana."

Eli yeza lisetyenziswa kakhulu ukunyanga umhlaza obizwa ngokuba yi-multiple myeloma . Lo ngumhlaza okhula kwi-bone mongo. Nangona kunjalo, ngamanye amaxesha ugqirha wakho unokugqiba ekubeni anike eli yeza nakwezinye iintlobo zomhlaza. Oku kuxhomekeke kumava kagqirha kunye nemeko yakho. Eli yeza lithengiswa kakhulu phantsi kwegama lebrendi i-NINLARO .

Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza

Ngaphambi kokuba uqale ukuthatha i-Ixazomib , kukho izinto ezibalulekileyo ekufuneka uzixelele ugqirha wakho okanye umongikazi malunga nempilo yakho. Kungcono ungazifihli ezi zinto, kuba eli yeza alifani kuwo wonke umntu.

• Isifo sezintso: Ukuba unesifo sezintso, okanye ukuba usebenzisa i-hemodialysis , ngokuqinisekileyo kufuneka usikhankanye.
• Isifo sesibindi: Ukuba unesifo okanye ubuthathaka besibindi, nceda usikhankanye naso.
• Ii-Allergy: Ukuba une-allergies kweli yeza , nakweyiphi na enye iyeza, ukutya, iidayi, okanye izithinteli, qiniseka ukuba uxelele ugqirha wakho . Ezi zinokuqala kwi-rash encinci ukuya kwi-reaction enzulu.
• Ukukhulelwa: Oku kubaluleke kakhulu ukuba ukhulelwe okanye uzama ukukhulelwa. Akucetyiswa ukuba ukhulelwe ngelixa usebenzisa eli yeza. Siza kuxoxa ngale nto ngokweenkcukacha kamva.
• Ukuba ungumama oncancisayo: Xelela ugqirha wakho ukuba uyancancisa, njengoko eli yeza linokudluliselwa kumntwana wakho ngobisi lwebele.

Ukuba usixelela ezi zinto ngokuchanekileyo, ugqirha wakho unokugqiba ukuba eli yeza lifanelekile kuwe okanye akunjalo, okanye ukuba idosi kufuneka itshintshwe na.

Ndingayisebenzisa njani kanye kanye le yeza?

Kubaluleke kakhulu ukulandela imiyalelo yokusebenzisa eli yeza ngokuchanekileyo. Ufanele ulithathe kanye njengoko ugqirha wakho ekuxelele, kanye njengoko libhaliwe kwileyibhile kagqirha.

• Le yikhaphu ethathwa ngomlomo . Ifanele iginywe ngamanzi.
• Oku kudla ngokuthathwa ngosuku oluthile lweveki, ngexesha elithile . Umzekelo, rhoqo ngoMvulo malunga nentsimbi ye-9 kusasa. Ngale ndlela, ukuyithatha ngosuku olunye, ngexesha elifanayo, kunceda ukugcina amayeza esebenza rhoqo emzimbeni.
• Musa ukuthatha ngaphezu koko ugqirha akuyaleleyo nangasiphi na isizathu. Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga ezibi kakhulu. Akufani namayeza, kufana nokusela ityhefu.
• Ufanele uqhubeke nokusela amayeza de ugqirha akuxelele ukuba "yeka ngoku." Musa ukuyeka phakathi.
• Eli yeza lifanele lithathwe ungenanto esiswini . Oko kukuthi, kungcono ukulithatha iyure enye ngaphambi kokutya okanye iiyure ezimbini emva kokutya. Ngale ndlela, iyeza liya kufunxwa ngcono ngumzimba.
• Ukuba unikwe elinye iyeza, elifana ne -dexamethasone , musa ukulisebenzisa eli yeza kunye ne-Ixazomib ngaxeshanye. Buza ugqirha wakho ukuba kufuneka kuthathe ixesha elingakanani phakathi kokuthatha la mayeza mabini.
• Musa ukuyisika, ukuyityumza, okanye ukuyihlafuna le kapsule. Yiginye yonke. Ukwenza njalo kunokutshintsha indlela esebenza ngayo iyeza, okanye ungafumana amayeza amaninzi ngaxeshanye.

Okubaluleke kakhulu: Eli yeza limiselwe wena kuphela . Musa ukulinika omnye umntu nangasiphi na isizathu, nokuba uneempawu ezifanayo nezakho.

Ukuba unika abantwana eli yeza: Ngokuqinisekileyo kufuneka udibane nogqirha wabantwana ngaphambi kokuba unike abantwana abancinci eli yeza. Lifuna unonophelo olukhethekileyo.

I-Overdose: Ukuba ucinga ukuba usele kakhulu eli yeza, yiya kwiziko lolawulo lwetyhefu elikufutshane okanye kwigumbi likaxakeka esibhedlele ngoko nangoko. Musa ukuchitha ixesha.

Wenza ntoni ukuba uphoswe yintlanganiso yamayeza?

Ngamanye amaxesha, ngenxa yokuxakeka okanye ukulibala, ungaphoswa ngamayeza akho. Ukuba oko kuyenzeka, ungakhathazeki.

• Thatha idosi oyiphosileyo ngokukhawuleza nje ukuba uyakhumbula.
• Nangona kunjalo, ukuba kungaphantsi kweeyure ezingama-72 (iintsuku ezi-3) ngaphambi kokuba uthathe idosi elandelayo, musa ukuyithatha idosi oyiphosileyo. Yitsibe uze uthathe idosi elandelayo ngexesha elicwangcisiweyo.
• Ukuba uyahlanza emva kokusela iyeza, musa ukuthatha elinye ipilisi ngaxeshanye. Thatha iyeza njengesiqhelo ngexesha elilandelayo elicwangcisiweyo.
• Ungaze uthathe amayeza aphindwe kabini okanye usebenzise amanye amayeza.

Ukuba unamathandabuzo malunga noku, kungcono ubuze ugqirha wakho okanye ingcali yezonyango.

Zeziphi ezinye izinto ezingahambelaniyo neli yeza kwaye zinokubangela iziphumo ebezingalindelekanga?

Eli yeza libizwa ngokuba yi -Ixazomib linokunxibelelana namanye amayeza kunye nemifuno oyithathayo. Oku kuthetha ukuba ukusebenza kweli yeza kunokuncipha, okanye iziphumo ebezingalindelekanga zinokwanda. Kungoko ke, kubaluleke kakhulu ukukwazi oku.

Nazi ezinye iziyobisi ezinokuthi i-Ixazomib isebenzisene nazo:

• I-Carbamazepine (iyeza elisetyenziselwa ukunyanga isifo sokuwa )
• I-Phenytoin (iyeza elisetyenziselwa ukunyanga isifo sokuwa )
• I-Rifampin (i-antibiotic esetyenziselwa ukunyanga isifo sephepha)
• I-St. John's Wort (le yimifuno, abanye abantu bayithatha njengeyeza elifana nokudakumba)

Olu luhlu aluphelelanga. Kusenokubakho nezinye ezininzi.

Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo (achazwe ngugqirha, athengiswa ngaphandle kwemvume kagqirha), onke amayeza owasebenzisayo, zonke iivithamini (izongezo zokutya) , kwaye ukuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi . Emva koko ugqirha angabona ukuba kuya kubakho naziphi na iingxaki ngala mayeza.

Izinto ekufuneka uzikhathalele ngokukodwa xa usebenzisa eli yeza:

Ngelixa usela eli yeza, ugqirha wakho uza kujonga impilo yakho rhoqo. Kodwa kufuneka ukhathalele nomzimba wakho.

• Oogqirha baza kuyijonga ngokusondeleyo imeko yakho. Ukuba ubona naziphi na iziphumo ebezingalindelekanga okanye nantoni na engaqhelekanga, xelela ugqirha wakho ngoko nangoko.
• Usenokuziva ungakhululekanga okanye uphazamisekile xa usebenzisa amayeza. Kodwa qhubeka nonyango de ugqirha wakho akuxelele ukuba uyeke.
• Eli yeza linokukwenza kube lula ukopha nokuba linxeba elincinci okanye ukukrweleka . Ukuba ubona nantoni na ebonakala ngathi ijika ibe luhlaza okwesibhakabhaka okanye ukopha ngenxa yokusikeka okuncinci okungayekiyo, xelela ugqirha wakho ngoko nangoko.
• Ngelixa usebenzisa eli yeza, kuya kufuneka uhlolwe igazi rhoqo (umsebenzi wegazi) . Oku kujonga indlela eli yeza elichaphazela ngayo umzimba wakho kunye nokuba amalungu anjengesibindi kunye nezintso asebenza kakuhle na.

Ingakumbi khumbula ngokukhulelwa nokuncancisa!

Le yindaba ebaluleke kakhulu . Nceda uyiqwalasele kakuhle le nto.

• Kuphephe ukukhulelwa: Kufuneka ukuphephe ukukhulelwa ngelixa usebenzisa eli yeza, kunye neentsuku ezingama-90 (malunga neenyanga ezi-3) emva kokuyeka iyeza. Ukuba ungumfazi, ngeli xeshaKubalulekile ukusebenzisa uhlobo lokuthintela ukukhulelwa olungelulo olwe-hormone, olufana nekhondom. Ukuba awuqinisekanga ngale nto, buza ugqirha wakho.
• Amadoda nawo kufuneka aqaphele: Ukuba uyindoda esela la mayeza, akufuneki uzame ukuba nomntwana ngelixa usela la mayeza, kwaye emva kweentsuku ezingama-90 emva kokuyeka amayeza. Oku kuthetha ukuba kufuneka uqinisekise ukuba umfazi wakho akakhulelwa ngeli xesha.
• Isizathu: Eli yeza linokubangela ingozi enkulu kumntwana ongekazalwa. Yiyo loo nto kucetyiswa ngamandla ukuba lingasetyenziswa.
• Ukuba ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko .
• Kuphephe ukuncancisa: Musa ukuncancisa umntwana wakho ngelixa usebenzisa la mayeza, kunye neentsuku ezingama-90 emva kokuyeka ukusebenzisa la mayeza.

Ukulandela le miyalelo kubaluleke kakhulu kukhuseleko lwakho nolomntwana wakho ozayo.

Zeziphi iziphumo ebezingalindelekanga onokuzifumana kweli yeza?

Njengalo naliphi na iyeza, i-Ixazomib inokubangela ezinye iziphumo ebezingalindelekanga. Asinguye wonke umntu ozifumanayo, kodwa kulungile ukuzazi ezo zinokwenzeka ukuze ukwazi ukuthatha amanyathelo okhuseleko afunekayo ngaphandle kokukhathazeka.

Ukuba uqaphela ezi ziphumo ebezingalindelekanga, kufuneka uxelele ugqirha wakho ngoko nangoko:

Ukuba ufumana naziphi na kwezi mpawu, musa ukucinga ukuba ziqhelekile. Bonana nogqirha ngokukhawuleza.

• Iimpendulo ze-allergy: Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukurhawuzelela umzimba wonke, ukudumba (ingakumbi ubuso, imilebe, nolwimi). Oku kungaba yingxamiseko.
• Utshintsho embonweni: Ukubona okufipheleyo, ukulahleka kombono ngequbuliso.
• Ukudideka: Ukungakwazi ukugxila, ukuziva ngathi ingqondo iyaphazamiseka.
• Ukuqhinwa: Ukungakwazi ukuya kwindlu yangasese kangangeentsuku ezininzi.
• Ukuncipha kokuchama: Ukuba uchama kancinci kunesiqhelo, isenokuba yingxaki yezintso.
• Urhudo: Ukuphuma kolwelo esiswini.
• Ukudinwa: Ukuziva ngathi ujikeleza.
• Ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo: Ukunyuka ngequbuliso kwesantya sentliziyo okanye ukuziva ngathi intliziyo ibetha ngendlela engahambelaniyo nesingqi.
• Ubuthathaka bemisipha: Ukuziva ngathi umzimba wakho uyaphelelwa ngamandla kwaye kunzima ukushukumisa amalungu akho omzimba.
• Isicaphucaphu/ukuhlanza: Ukuziva unesicaphucaphu esiswini sakho, uzive ngathi uza kuhlanza, okanye ukuhlanza ngokwenene.
• Intlungu, ukurhawuzelela, ukungaziva ezandleni okanye ezinyaweni: Intlungu, ukurhawuzelela, ukungaziva, okanye ukuphelelwa luvakalelo ezandleni okanye ezinyaweni, ukuqala kwiincam zeminwe. OkuIsenokuba luphawu lwemeko ebizwa ngokuba yi-peripheral neuropathy .
• Iimpendulo zesikhumba: Ukuba bomvu, ukudumba, ukuxobuka, okanye ukuxobuka kwesikhumba (oku kungenzeka nangaphakathi emlonyeni).
• Ukuphefumla nzima: Ukuziva ngathi unengxaki yokuphefumla nokuba umi nje, kungekuphela nje xa unyuka izinyuko.
• Iimpawu zosulelo: umkhuhlane, ukugodola, ukukhohlela, umphimbo obuhlungu, iintlungu xa uchama, okanye ubunzima bokuchama.
• Iimpawu kunye neempawu zokulimala kwesibindi: Umchamo otyheli okanye omdaka omnyama; ukuziva ungaphilanga, uzive ngathi unomkhuhlane okanye umkhuhlane; indle ekhanyayo; ukungabi namdla wokutya; isicaphucaphu; iintlungu kwicala eliphezulu lasekunene lesisu; ukuziva udiniwe kakhulu kwaye ungenabomi; ukutyheli kwamehlo nolusu.
• Ukudumba: Ukudumba kwamaqatha, iinyawo, nezandla.
• Ukopha okanye ukukrwela okungaqhelekanga: Ukujika nje kube luhlaza okwesibhakabhaka kwiindawo ezithile, okanye ukopha okubonakala ngathi kuyayeka kwinxeba elincinci.

Ngokwesiqhelo akukho ngxaki inkulu, kodwa ukuba iyaqhubeka, kukho izinto ezimbalwa ekufuneka uzixelele ugqirha wakho :

Nangona ezi mpawu zingasoloko zimbi, ukuba ziyaqhubeka okanye ziyakukhathaza, kulungile ukuxelela ugqirha wakho.

• Umqolo obuhlungu
• Umbono ofipheleyo (oku kukhankanyiwe apha ngasentla, kodwa kunokuphela emva kweentsuku ezimbalwa. Kodwa ndixelele ukuba kuyaqhubeka).

Khumbula, olu luhlu lulwampu nje lweziphumo ebezingalindelekanga. Ukuba ubona nantoni na engaqhelekanga okanye engaqhelekanga, xelela ugqirha wakho ngayo. Musa ukoyika, kodwa qaphela.

Ndingazigcina njani ezi pilisi?

Ukugcina amayeza akho ngendlela efanelekileyo kukwayinxalenye yonyango.

• Yigcine kude nabantwana! Oku kubaluleke kakhulu. Ukuba abantwana abancinci bayazibamba ezi zinto, zinokuba yingozi kakhulu.
• Gcina iyeza kwiphakheji yalo yokuqala . Ngale ndlela, akuyi kubakho kudideka malunga nokuba leliphi iyeza.
• Gcina kubushushu begumbi . Oko kukuthi, phakathi kwe-15 kunye ne-30 degrees Celsius (59 kunye ne-86 degrees Fahrenheit). Musa ukugcina kwiindawo ezishushu kakhulu, ezifana nefriji.
• Musa ukusebenzisa amayeza aphelelwe lixesha. Walahle.

Ngokuzinyamekela ezi zinto zincinci, ungakhusela umgangatho wamayeza.

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule

I-Ixazomib liyeza elinamandla elinokukunceda ulwe nomhlaza. Xa ulisebenzisa, kubalulekile ukulandela imiyalelo kagqirha wakho ngononophelo, unike ingqalelo emzimbeni wakho, kwaye uxele ugqirha wakho ngayo nayiphi na imiphumo emibi.Kubaluleke kakhulu ukwazisa.

Lumka ngakumbi malunga neengcebiso ezinikiweyo malunga nokukhulelwa nokuncancisa, kuba zinokuba nefuthe elikhulu kwimpilo yakho neyentsapho yakho kwixesha elizayo.

Ukuba uneminye imibuzo okanye iinkxalabo malunga nale yeza, ungathandabuzi ukubuza ugqirha wakho, umongikazi, okanye ikhemisti. Bakho ukukunceda.

Siyathemba ukuba olu lwazi luza kukunceda. Sikunqwenelela ukuchacha ngokukhawuleza!

I- Ixazomib, umhlaza, amayeza omhlaza, i-multiple myeloma, i-Multiple Myeloma, i-NINLARO, unyango lomhlaza, iziphumo ebezingalindelekanga