Ngaba ukhe wafunyaniswa unePrimary Biliary Cholangitis ( PBC ) , okanye njengoko oogqirha beyibiza njalo? Ukuba kunjalo, mhlawumbi sele uqalile unyango. Kodwa ngaba ngamanye amaxesha uvakalelwa kukuba amayeza owasebenzisayo awancedi kangako njengoko ucinga, kwaye isifo sinjalo kanye? Kuqhelekile ukuziva ngaloo ndlela, kwaye ungakhathazeki ngayo. Namhlanje, siza kuthetha ngento eyenzekayo ukuba unyango lwakho lwePBC alusebenzi, indlela yokulubona, kunye nento omawuyenze emva koko.
Okokuqala, yintoni i-PBC ngokulula?
Cinga ngesibindi sethu njengenye yezona mveliso zikhulu emzimbeni wethu. Ulwelo olubalulekileyo oluveliswa kule mveliso lubizwa ngokuba yi-'bile'. Le bile isinceda ukuba sitye ukutya esikutyayo. Le bile ikhutshwa esibindini ngenkqubo ethambileyo kakhulu yeetyhubhu ezincinci ( ii-bile ducts ).
Kwimeko ebizwa ngokuba yi-PBC, isiphene kwinkqubo yethu yokuzikhusela komzimba sihlasela le mibhobho yenyongo ethambileyo size sibangele ukuba idumbe ngaphakathi. Kufana nombhobho wamanzi ovalwayo. Emva koko, inyongo ayikwazi ukuhamba kakuhle ize iqale ukuqokelelana ngaphakathi esibindini.
Kwinqanaba lokuqala, kusenokungabikho zimpawu. Kodwa njengoko le nyongo iqokelelana ngokuhamba kwexesha, yonakalisa iiseli zesibindi kwaye ibangele amanxeba. Xa le meko iba mandundu, ibizwa ngokuba yi-cirrhosis . Ukuba ayinyangwa kakuhle, inokukhokelela nasekungasebenzini kwesibindi . Yiyo loo nto kubaluleke kakhulu ukuqala unyango ngokukhawuleza.
Iyeza lokuqala elinikwa ngugqirha - i-UDCA
Wakuba ufunyenwe une-PBC, iyeza lokuqala ugqirha wakho aza kukuqalisa ngalo yi- Ursodeoxycholic acid . Ekubeni kunzima ukukhumbula igama elide, sonke silibiza ngokuba yi-UDCA ngamafutshane.
Oko kwenziwa leli yeza le-UDCA kukunceda inyongo eqokelelene esibindini ukuba iphume ngokulula. Oku kunciphisa umonakalo esibindini. Kodwa kukho into enye ebalulekileyo ekufuneka siyiqonde sonke.
Eli yeza le-UDCA alinakunyanga ngokupheleleyo i-PBC. Nangona kunjalo, linokumisa isifo ukuba singaqhubeki ngokukhawuleza, lilawule umonakalo wesibindi, kwaye likuncede uphile ubomi obuqhelekileyo.
Kodwa ingxaki kukuba, eli yeza alisebenzi ngendlela efanayo kubo bonke abantu. Abanye abantu abafumani ziphumo abazilindeleyo kulo.
Wazi njani ukuba iyeza alisebenzi?
Izifundo zifumanise ukuba malunga nama-40% abantu abasebenzisa i-UDCA, okanye malunga nabantu abane kwabalishumi, abafumani zibonelelo zilindelekileyo kweli yeza. Inani elincinci labantu lifumana iziphumo ebezingalindelekanga ezifana nokuphazamiseka kwesisu kunye norhudo, nto leyo eyenza kube nzima ukuqhubeka nokusebenzisa eli yeza.
Ukuba unyango lwakho alusebenzi kakuhle, ungaqhubeka nokuba neempawu ezifana nezi okanye ube neempawu ezibi ngakumbi.
| Uphawu | Indlela evakalelwa ngayo |
|---|---|
| Ukuziva udiniwe kakhulu rhoqo | Ukuziva ungenabomi nokuba ulele kakuhle kwaye ungenzi nto. |
| Ukukrwela ulusu | Ukurhawuzelela okungapheliyo emzimbeni wonke, ingakumbi ebusuku. |
| Ukutyheli kolusu namehlo | Amhlophe emehlweni naselusu ajika abe tyheli, njengakwi-jaundice. |
| Amehlo nomlomo owomileyo | Umlomo owomileyo rhoqo kunye nomvakalelo wokomisa, njengesanti emehlweni. |
| Intlungu kwicala eliphezulu lasekunene lesisu | Intlungu ebuhlungu evela kwindawo yesibindi, oko kukuthi, kwicala lasekunene lesisu, phantsi kweembambo. |
| Ukudumba kwamalungu kunye nesisu | Ingakumbi ukudumba emilenzeni, emaqatheni, uze emva koko ungene esiswini. |
Ngubani onokuthi angayithathi i-UDCA?
Oogqirha baye baqaphela ukuba abanye abantu banokufumana iziphumo ezinciphileyo ezivela kwi-UDCA. Ezi ziquka:
- Abantu abasele benesifo sesibindi.
- Abantu abanee-enzymes zesibindi eziphezulu kakhulu ezibizwa ngokuba yi-gamma-glutamyl transferase kunye ne-alkaline phosphatase egazini labo.
- Amadoda (nangona i-PBC ixhaphake kakhulu kwabasetyhini, inokuba nzima ngakumbi kumadoda).
- Abafazi baxilongwe bene-PBC ngaphambi kokuba bafikelele kwiminyaka engama-45 ubudala.
Ungakuqinisekisa njani oku, gqirha?
Nokuba iimpawu zakho ziyaqhubeka, ugqirha akayi kugqiba ngoko nangoko ukuba "amayeza awasebenzi." Kukho indlela yokwazi ngokuqinisekileyo.
Wakuba uqalile unyango, ugqirha wakho uza kukujonga rhoqo. Badla ngokuyalela uvavanyo lwegazi rhoqo kwiinyanga ezi-3 ukuya kwezi-6. Kodwa ngamanye amaxesha kungathatha unyaka ukuqiniseka ukuba eli yeza liyasebenza na kuwe.
Olu vavanyo lwegazi lujonga ikakhulu amanqanaba e-enzyme yesibindi sakho, ngakumbi i-Alkaline Phosphatase (ALP) kunye ne-Bilirubin . Ukuba la manqanaba asephezulu kakhulu kunesiqhelo emva kweenyanga ezininzi usebenzisa i-UDCA, inokuba luphawu lokuba unyango alusebenzi njengoko bekulindelwe.
Ukuba oko kuyenzeka, ugqirha wakho unokugqiba ekubeni afake iyeza elitsha kwi-UDCA yakho okanye athethe nawe ngolunye unyango.
Ngoko ke ndimele ndenze ntoni?
Le yeyona nto ibalulekileyo ekufuneka uyazi kweli nqaku.
Ukuthetha ngokukhululekileyo nangokunyanisekileyo nogqirha wakho.
Ukuba iimpawu zakho aziphucuki okanye zibonakala zisiba mandundu, qiniseka ukuba uyayikhankanya kugqirha wakho xa uphinda umbona. Musa ukuyifihla inkcazelo, ucinge ukuba, "Oku kumele ukuba kuqhelekile," okanye ucinga ukuba kuya kumkhathaza ugqirha. Yonke into encinci ocinga ukuba ibalulekile xa usenza izigqibo zonyango.
Khumbula, ukuba nje iyeza lokuqala alizange lisebenze akuthethi ukuba liphelile. Amayeza aphucuke kakhulu. Kukho ezinye iindlela kunye namayeza amatsha okunceda ukulawula imeko yakho. Eyona nto ibalulekileyo kukuba wena nogqirha wakho nisebenzisane njengeqela.
Umyalezo Wokuya Ekhaya
- I-PBC sisifo esonakalisa imibhobho emincinci ethwala inyongo iye esibindini. Ukuba ayinyangwa kakuhle, inokukhokelela ekonakaleni okukhulu kwesibindi ngokuhamba kwexesha.
- I-UDCA lolona nyango luphambili nolusetyenziswa kakhulu kwi-PBC, kodwa ayisebenzi kakuhle kuye wonke umntu.
- Ukuba iimpawu ezinje ngokudinwa rhoqo, ulusu olurhawuzelelwayo, kunye nokutyheli kwamehlo ziyaqhubeka nangona usebenzisa amayeza, oko kuthetha ukuba unyango alufanelekanga kuwe.
- Ukuthetha nogqirha wakho malunga neempawu zakho kunye neemvakalelo zakho yeyona nto ilungileyo onokuyenza kwimpilo yakho.
- Nokuba unyango olunye alusebenzi, zikho ezinye iindlela kunye namayeza okulawula imeko yakho. Ngoko ke musa ukoyika okanye uxhalabe.
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