Masifunde ngale mithi ikhethekileyo (iSacubitril; iValsartan) enikwa isifo sentliziyo.

Ngaba nawe unengxaki yokuphefumla, uziva ngathi uza kuphelelwa ngamandla nokuba ukhe wazama kancinci? Okanye ngaba ugqirha wakho ukuxelele ukuba unesifo sentliziyo? Ukuba kunjalo, kusenokwenzeka ukuba unikwe iyeza elibizwa ngokuba yiSacubitril; Valsartan (---‍; --) . Lidla ngokuba phantsi kwegama lophawu elithi `Entresto`. Ngoko ke, namhlanje siza kuthetha ngale yeza, indlela yokulisebenzisa, kunye nento ekufuneka uyilumkele. Njengokuba ubuya kuxelela umhlobo wakho.

Luhlobo luni lonyango olu? Kutheni lunikwa olu hlobo?

Ngamafutshane, le 'Sacubitril; IValsartan yindibaniselwano yamayeza amabini. Omnye ngu `Sacubitril` க்ய-஬ி-ட்ரில்),-க்ய-஬ி-ட்ரில் - க்ய-஬ி-ட்ரில்), eli liyeza leqela `(neprilysin inhibitor)`. Enye yi `Valsartan` கா-தன்),-வலஸாட் -ஸாட்ரில் - க்ய-஬ி-ட்ரில்), eli liyeza le `(angiotensin II receptor blocker - ARB)` iqela. La mayeza mabini asebenza kunye. Eli yeza linikezelwa ikakhulu kubantu abanesifo sentliziyo . Ukungaphumeleli kwentliziyo yimeko apho intliziyo ingakwazi ukupompa igazi elaneleyo emzimbeni. Cinga ngayo, intliziyo ifana nepompo yamanzi. Ukuba ayisebenzi kakuhle, kuba ngathi amanzi awahambi emzimbeni wonke, kwaye igazi alihambi emzimbeni wonke. Kulapho ke kuvela khona izinto ezifana nokudinwa nokuphefumla kancinci. Ngoko ke, into eyenziwa leli yeza kukunceda amandla okupompa kwentliziyo kunye nokunciphisa umthwalo entliziyweni. Ngamanye amaxesha oogqirha banokusebenzisa eli yeza nakwezinye iimeko zonyango. Oko kuxhomekeke kugqirha wakho ukuba agqibe.

Ndimele ndimxelele ntoni ugqirha wam ngaphambi kokuba ndiqalise eli yeza?

Oku kubaluleke kakhulu. Ngaphambi kokuba uqale ukusebenzisa eli yeza elithi `Sacubitril; Valsartan`, ngokuqinisekileyo kufuneka uxelele ugqirha wakho okanye umongikazi ngezi zinto. Musa ukufihla nantoni na.

• Xelela ugqirha wakho ukuba unesifo seswekile ( iDiabetes Mellitus) , ingakumbi ukuba usebenzisa iyeza elithi aliskiren.
• Ukuba uyazi ukuba inqanaba le-potassium egazini lakho liphezulu .
• Ukuba unesifo sezintso .
• Ukuba unesifo sesibindi .
• Ukuba uxinzelelo lwakho lwegazi luphantsi (` uxinzelelo lwakho lwegazi oluphantsi`) .
• Le yi-'Sacubitril; iValsartan', okanye `(Ukuba ukhe waba ne-allergy kumayeza abizwa ngokuba yi-ACE inhibitors (umz., i-enalapril, i-lisinopril), amayeza abizwa ngokuba yi-angiotensin II receptor blockers (ARBs) (umz., i-losartan, i-telmisartan), naluphi na olunye unyango, ukutya, iidayi zokutya, okanye izithinteli .
• Ukuba ukhulelwe, okanye uzama ukukhulelwa . Oku kubaluleke kakhulu, siza kuthetha ngako kamva.
• Ukuba ungumama oncancisayo .

Wakuba uzicingile ezi zinto, ugqirha wakho unokugqiba ngokuchanekileyo ukuba eli yeza likulungele na okanye alikufanelanga, kwaye angalinika njani.

Uyisebenzisa njani le mithi ngokuchanekileyo?

Xa usela iyeza, eyona nto ibalulekileyo kukulisebenzisa ngokuchanekileyo. Ngaphandle koko, alizukusebenza kakuhle.

• Indlela yokuthatha: Le ifumaneka kwifomu yepilisi. Ifanele ithathwe ngomlomo. Zama ukuthatha idosi emiselweyo, kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanayo yonke imihla . Ngale ndlela, iyeza liya kusebenza ngendlela efanayo.
• Ukutya okanye ungakutya?: Ungayithatha le pilisi usitya okanye ungakutyanga. Nangona kunjalo, abanye abantu banokuchaphazeleka sisisu ukuba bayithatha ngaphandle kokutya. Kwimeko enjalo, kungcono ukuyithatha kunye nokutya.
• Ukuyekisa: Qhubeka usebenzisa eli yeza de ugqirha wakho akuxelele ukuba uyeke. Musa ukuyeka ngequbuliso. Ukuba kufuneka uyeke, thetha nogqirha wakho kwaye ulandele imiyalelo yakhe.
• Ngaba eli yeza linganikwa abantwana?: Ewe, ngamanye amaxesha eli yeza linganikwa abantwana abaneminyaka eli-1 ubudala abaneengxaki ezithile zentliziyo. Nangona kunjalo, ngokuqinisekileyo lifuna ukhathalelo olukhethekileyo kunye nolawulo lwezonyango.
• Okufanele ukwenze xa usela kakhulu: Ukuba ucinga ukuba usele kakhulu kweli yeza, okanye ukuba ngempazamo usele iipilisi ezininzi kakhulu, yiya kwigumbi likaxakeka lesibhedlele esikufutshane okanye utsalele umnxeba kwiziko lokulawula ityhefu ngoko nangoko. Musa ukuchitha ixesha.
• Musa ukwabelana: Oku kukwayinto ekufuneka uyikhumbule. Eli yeza limiselwe wena kuphela, ukunyanga imeko yakho. Ngoko ke, ungaze unike abahlobo bakho, izalamane, okanye amanye amalungu osapho lakho eli yeza, nokuba bathi banengxaki efanayo neyakho.

Wenza ntoni ukuba uphoswe yintlanganiso yamayeza?

Ngamanye amaxesha siyalibala ukusela amayeza ethu. Ukuba oko kuyenzeka, ungakhathazeki.

• Sela amayeza akho ngokukhawuleza xa ukhumbula.
• Nangona kunjalo, ukuba sele kusondele ixesha lomthamo wakho olandelayo xa ukhumbula, yeka umthamo ophosiweyo uze uthathe umthamo olandelayo ngexesha elicwangcisiweyo.
• Ungaze uthathe idosi ephindwe kabini ukuze ubuyisele idosi oyiphosileyo.Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga.

Ngawaphi amanye amayeza angafanele asetyenziswe kunye nale yeza, okanye anokubangela iziphumo ebezingalindelekanga?

Eli linqaku elibaluleke kakhulu. Eli yeza elibizwa ngokuba yi-`Sacubitril; Valsartan` linokubangela iingxaki xa lisetyenziswa namanye amayeza athile. Oko kukuthi, ukusebenza kweli yeza kunokuncipha, okanye kunokwanda, okanye iziphumo ebezingalindelekanga ezintsha zinokwenzeka.

Musa ukuthatha 'iSacubitril; iValsartan' kunye nala mayeza:

* Ukuba unesifo seswekile, sebenzisa iyeza elithi `(aliskiren)`.

* Ngamayeza abizwa ngokuba yi-`(i-enzyme eguqula i-Angiotensin - i-ACE inhibitors)`. Umzekelo, amayeza anje nge-`benazepril`, `captopril`, `enalapril`, `fosinopril`, `lisinopril`, `ramipril`. Nokuba uyeka ukuthatha amayeza anjalo kangangeentsuku ezimbalwa, ayingombono ulungileyo ukuqala i-`Sacubitril; Valsartan`. Thetha nogqirha wakho ngayo.

* Kunye neyeza `(tranylcypromine)`.

La mayeza alandelayo anokusebenzisana ne-'Sacubitril; iValsartan'. Ngoko ke, xelela ugqirha wakho ngale mithi:

• Ezinye iintlobo ze-Angiotensin II receptor blockers (ARBs). Imizekelo: azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, okanye valsartan (ukuba uthatha i-valsartan ngokwahlukileyo ukongeza kwi-valsartan kweli yeza).
• Amayeza afana ne-`(celecoxib)`.
• `(lithium)` (iyeza elinikwa izifo zengqondo).
• `(Ii-NSAID)` - La ngamayeza asetyenziselwa ukunyanga iintlungu kunye nokudumba. Imizekelo: `ibuprofen`, `naproxen`. La mayeza angathengwa rhoqo kwikhawuntara kwiikhemesti, ngoko ke ukuba uyawasebenzisa, khankanya wona.
• Ii-diuretics ezigcina i-potassium. Imizekelo: i-amiloride, i-spironolactone, i-triamterene.
• Izongezo zePotassium okanye izinto ezithatha indawo yetyuwa etyebileyo kwiPotassium.

Olu luhlu lusenokungabandakanyi onke amayeza. Ke ngoko, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini, amayeza esintu, amayeza athengiswa ngaphandle kwemvume kagqirha, kunye namayeza esintu. Kwakhona, nyaniseka kugqirha wakho malunga nawo nawaphi na amayeza owasebenzisayo, kuquka amayeza owatshayayo, utywala, okanye ezinye iziyobisi ezingekho mthethweni. Oku kunokuchaphazela indlela eli yeza elisebenza ngayo.

Yintoni endifanele ndiyilumkele ngakumbi xa ndisebenzisa eli yeza?

Nceda uqaphele la manqaku xa usebenzisa eli yeza ukuqinisekisa ukhuseleko lwakho kunye nokufumana iingenelo eziphezulu kweli yeza.

• Lumka kwiimpawu: Ukuba iimpawu zakho zesifo sentliziyo (ezifana nokuphefumla kancinci, ukudinwa, ukudumba emilenzeni) aziphucuki emva kokuqalisa eli yeza, okanye ukuba zibonakala zisiba mandundu, xelela ugqirha wakho ngoko nangoko.
• Ukukhulelwa (oku kubaluleke kakhulu!):

Musa ukukhulelwa ngelixa usela iSacubitril; iValsartan. Eli yeza linokubangela ingozi enkulu kusana olungekazalwa, kwaye linokuba yingozi ebomini. Ke ngoko, ukuba uceba ukukhulelwa, okanye ukuba ucinga ukuba ukhulelwe, yeka ukuthatha eli yeza ngoko nangoko kwaye uxelele ugqirha wakho. Ugqirha wakho uza kukunika iingcebiso ezifanelekileyo. Buza ugqirha wakho ngolwazi oluthe kratya.

• Ukozela okanye isiyezi: Abanye abantu banokuziva besozela okanye benesiyezi xa besebenzisa eli yeza. Ngoko ke, kuphephe ukuqhuba, ukusebenzisa oomatshini abanzima, okanye ukwenza nantoni na efuna ukuqwalaselo kunye nokuphaphama ude wazi kakuhle ukuba eli yeza likuchaphazela njani. Musa ukuphakama kwindawo ohleli kuyo okanye uhlale phantsi kwindawo omi kuyo ngequbuliso. Lumka ngakumbi ukuba ukhulile. Ukutshintsha iindawo rhoqo kunokunciphisa umngcipheko wokuba nesiyezi kunye nokuwa.
• Utywala: Lumka utywala kangangoko unako ngelixa usebenzisa eli yeza. Utywala bungaphazamisa ukusebenza kweli yeza kwaye bunokunyusa iziphumo ebezingalindelekanga.
• Izinto ezithatha indawo yetyuwa: Ezinye izinto ezithatha indawo yetyuwa zine potassium. Kufuneka uqaphele amanqanaba akho e potassium ngelixa usebenzisa eli yeza, ngoko ke musa ukusebenzisa izinto ezithatha indawo yetyuwa ngaphandle kokuba ugqirha wakho ekuxelele ngokuthe ngqo.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengazo zonke iziyobisi, iSacubitril; iValsartan inokubangela iziphumo ebezingalindelekanga kwabanye abantu. Asinguye wonke umntu ozifumanayo, kodwa kulungile ukuzazi. Ukuba ufumana naziphi na kwezi ziphumo bezingalindelekanga zilandelayo, xelela ugqirha wakho okanye isibhedlele ngokukhawuleza:

• Iimpendulo ze-allergy:
• Izilonda zesikhumba, ezifana ne-eczema, ukurhawuzelela, kunye ne-hives.
• Ukudumba kobuso, imilebe, ulwimi, okanye umqala (oku kuyingozi kakhulu kuba kunokubangela ubunzima bokuphefumla).
• Amanqanaba aphezulu e-potassium egazini:
• Ukuziva ngathi uneentlungu esifubeni.
• Ukubetha kwentliziyo ngequbuliso kuyakhawuleza kwaye kungahambelani.
• Ukuziva ubuthathaka kunye nokungaziva mnandi kwimisipha.
• Ukulimala kwezintso:
• Ukuziva kunzima ukuchama.
• Ukuchama kancinci okanye ngaphezulu kunesiqhelo.
• Utshintsho kumbala womchamo.
• Uxinzelelo lwegazi oluphantsi:
• Ukuziva unesizungu, ingakumbi xa umi ngenyawo.
• Ndiziva ndityhafile, amehlo ejika abe luhlaza okwesibhakabhaka.
• Ukuziva ngathi uza kuwa umi.
• Ukuziva ubuthathaka kwaye udiniwe ngendlela engaqhelekanga.

Iziphumo ebezingalindelekanga ezidweliswe ngezantsi azisoloko ziyinto ekufuneka uyixhalabele. Kodwa ukuba ziyaqhubeka okanye ziyakukhathaza, xelela ugqirha wakho:

• Ukukhwehlela: Abanye abantu banokuba nokukhwehlela okomileyo xa besebenzisa eli yeza.

Ukuba ufumana naziphi na iimpawu ezingaqhelekanga okanye iziphumo ebezingalindelekanga ezingadweliswanga apha, thetha nogqirha wakho ngazo. Ungakhathazeki, uninzi lwezi zinto lunokulawulwa.

Uligcina njani eli yeza likhuselekile?

Kubaluleke kakhulu ukugcina amayeza ekhuselekile.

• Yigcine kude nabantwana nezilwanyana zasekhaya. Oku kuqhelekile kuwo onke amayeza.
• Gcina kubushushu begumbi (phakathi kwama-20 nama-25 degrees Celsius, phakathi kwama-68 nama-77 degrees Fahrenheit). Khusela kubushushu obugqithisileyo, ukukhanya, kunye nokufuma. Oku kuthetha ukuba ungayigcini kwiindawo ezifana negumbi lokuhlambela.
• Gcina ibhotile okanye ipakethe enamayeza ivaliwe kakuhle.
• Musa ukusebenzisa amayeza aphelelwe lixesha. Umhla wokuphelelwa ukhankanyiwe kwiphakheji.

Uzilahla njani amayeza angasetyenziswanga okanye aphelelwe lixesha?

• Eyona nto ingcono onokuyenza kukunika amayeza "kwinkqubo yokubuyisela amayeza emva kokuthatha amayeza." Buza kwikhemesti yakho okanye kwisikhululo samapolisa esikufutshane ukuze ubone ukuba banazo na ezo nkqubo.
• Ukuba oko akunakwenzeka, jonga ilebheli yamayeza okanye ipakethi ukuze ubone ukuba kukho imiyalelo yokuba ungayilahla njani iyeza enkunkuma okanye uyikhuphele endlwini yangasese.
• Ukuba awuqinisekanga, buza ugqirha wakho okanye ingcali yezemithi.
• Ukuba liyeza elinokulahlwa kwinkunkuma, likhuphe kwisitya, ulixube nenkunkuma yekati esele isetyenzisiwe, umhlaba, okanye ikofu, ulifake kwibhegi okanye kwisitya esivalekayo, uze ulilahle kwinkunkuma. Oku kwenzelwa ukuthintela abantwana abancinci okanye izilwanyana ukuba zingangeni kulo zize zenze ingozi.

Izinto ezibalulekileyo ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, ngoko ke sithethe kakhulu ngale chiza `Sacubitril; Valsartan` (Entresto), akunjalo? Okokugqibela, nazi izinto ezibalulekileyo ekufuneka uzikhumbule:

• Eli yeza liyeza elibalulekileyo elinceda ukulawula ukusilela kwentliziyo yakho.
• Soloko uthatha idosi emiselweyo ngexesha elimiselweyo, njengoko ugqirha wakho ekuyalele. Musa ukutsiba ukutya okanye ukuthatha okungaphezulu kokufunekayo.
• Qiniseka ukuba uxelela ugqirha wakho ngamanye amayeza owasebenzisayo kunye nezinye izifo onazo.
• Musa ukulisebenzisa eli yeza ukuba ukhulelwe okanye uzama ukukhulelwa. Lumka kakhulu.
• Lumka ngemiphumo emibi. Xelela ugqirha wakho ukuba ubona into engaqhelekanga.
• Ukuba unemibuzo okanye amathandabuzo, ungabi namahloni okubuza ugqirha wakho okanye ikhemisti.

Ukuba ulandela la manyathelo ngokuchanekileyo, eli yeza liya kukwazi ukunika iziphumo ezilungileyo kwimpilo yentliziyo yakho. Ndikunqwenelela ukuchacha ngokukhawuleza! I-Sacubitril, i-Valsartan, i-Entresto, ukusilela kwentliziyo, isifo sentliziyo, amayeza entliziyo, uxinzelelo lwegazi