Ngaba nawe uziva ubuthathaka rhoqo, iintlungu zamalungu, kunye neengxaki zolusu? Mhlawumbi ugqirha wakho ukucelile ukuba wenze uvavanyo lwe-ANA ngexesha elinje. Xa usiva eli gama, abanye abantu bayoyika kancinci, becinga, "Luhlobo luni lwesifo esikhulu olu vavanyo?" Kodwa eneneni luvavanyo lwegazi oluqhelekileyo nolulula kakhulu. Ngoko masicacise yonke imibuzo onayo ngalo namhlanje. Makhe sibone ukuba olu vavanyo lwe-ANA luyintoni, kutheni lwenziwe, kunye nokuba iziphumo zithini ngokwenene.
Kalula nje, yintoni olu vavanyo lwe-ANA?
Ukuze sikuqonde oku, kufuneka siqale sazi ukuba ziintoni ' ii-antibodies '. Khawuthelekelele ukuba umzimba wethu lilizwe. Emva koko ii-antibodies zifana nemikhosi yokhuselo yelo lizwe . Umsebenzi wezi antibodies kukubona nokulwa neentshaba ezifana neentsholongwane (iibhaktheriya, iintsholongwane) ezivela ngaphandle nokusikhusela kwizifo.
Kodwa, ngamanye amaxesha ukhuselo lwethu lwenza impazamo encinci. Endaweni yokuba lutshaba oluvela ngaphandle, luphambanisa iiseli zethu eziphilileyo kunye nezicubu zethu njengotshaba. Emva koko luqala ukuhlasela ezo seli ziphilileyo. Sizibiza ezi antibodies ezihlasela imizimba yethu ngempazamo ngokuthi 'zii-autoantibodies' .
Ngoko ke, uvavanyo lwe-Antinuclear Antibody (ANA) luvavanyo lwegazi olujonga ezi 'autoantibodies' egazini lakho. Igama elithi 'Antinuclear' lithetha 'ngokuchasene nenucleus'. Oku kuthetha ukuba ezi autoantibodies zihlasela ngokukodwa inucleus, eliziko lolawulo lweeseli zethu.
Ukubakho kwezi autoantibodies emzimbeni wakho luphawu lokuba usenokuba 'nesifo sokuzikhusela komzimba ', imeko apho inkqubo yomzimba yokuzikhusela izijikela ngokwayo . Umzekelo:
- Isifo seLupus (iSystemic Lupus Erythematosus - SLE)
- Irheumatoid arthritis
- I-Scleroderma
- Isifo sikaSjögren
Ziziphi iimpawu ezinokwenza ugqirha acebise olu vavanyo?
Izifo ezizikhusela ngokwazo emzimbeni zineempawu ezininzi. Ukuba sele unenye okanye ngaphezulu kwezi mpawu zingezantsi ixesha elide, ugqirha wakho unokucebisa uvavanyo lwe-ANA ukuze kufunyanwe unobangela.
| Uphawu | Inkcazo |
|---|---|
| Intlungu yamalungu kunye nemisipha | Ukuqina kwamalungu ekuseni, ukudumba, kunye nentlungu engapheliyo. |
| Ukudinwa | Ukuziva ungenabomi nokuba ulala kangakanani na. |
| Umkhuhlane ophindaphindayo | Ukuba nemvakalelo engapheliyo yokuba nobushushu nomkhuhlane ngaphandle kwesizathu esithile. |
| Urhawuzelelo lwebhabhathane | Amaqhuqhuva abomvu, amile okwebhabhathane avela ezidleleni nangaphaya kwempumlo (olu luphawu oluphambili lwe-lupus). |
| Ukungabi nangqondo kwamalungu | Ukurhawuzelela okanye ukuba ndindisholo ezandleni okanye ezinyaweni. |
| Ukulahleka kweenwele | Ukulahleka kweenwele okuninzi kunokuqhelekileyo. |
| Uvelwano ekukhanyeni | Ukucaphuka okanye ukungakhululeki kolusu xa ubekwe elangeni okanye ekukhanyeni okuqaqambileyo. |
Izinto ekufuneka uzazi ngaphambi kokuba wenze uvavanyo
Akukho nto ikhethekileyo ekufuneka uyenze ngaphambi kolu vavanyo. Akufuneki uzile ukutya okanye wenze nantoni na ekhethekileyo. Nangona kunjalo, kubalulekile ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo ngoku (kuquka iivithamini kunye nezongezo ). Amanye amayeza anokuchaphazela iziphumo ze-ANA.
Ulwenza njani uvavanyo?
Le yinkqubo elula kakhulu. Ilabhoratri ithatha isampuli yegazi encinci kumthambo osengalweni yakho. Le nkqubo igqitywa ngemizuzu embalwa. Iplasta encinci ifakwa kwindawo apho igazi lithathwe khona. Emva koko, ungaya ekhaya njengesiqhelo. Isampuli yegazi ivavanywa kwilabhoratri.
Ingaba iziphumo ze-ANA... Zilungile (+)? Zimbi (-)? Kuthetha ukuthini oku?
Le yeyona ngxaki inkulu wonke umntu anayo.
- Iziphumo ezingezizo (-): Oku kuthetha ukuba akukho ma-autoantibodies afunyenweyo egazini lakho. Oku kuthetha ukuba akunakwenzeka ukuba unesifo sokuzikhusela komzimba.
- Iziphumo ezilungileyo (+): Oku kuthetha ukuba ii-autoantibodies zifunyenwe egazini lakho.
Kodwa kukho into ekufuneka uyikhumbule apha.
Into ebalulekileyo kukuba uvavanyo lwe-ANA olubonisa ukuba une-ana aluthethi ukuba unesifo sokuzikhusela komzimba.
Enyanisweni, phakathi kwe-3% kunye ne-15% yabantu abaphilileyo abangenazo iingxaki zempilo ezifihlakeleyo banokuba novavanyo lwe-ANA olubonisa ukuba bane-HIV. Oku kunokubangelwa ngamayeza athile, usulelo lwentsholongwane , kunye nezinye iimeko zempilo.
Oku kuthetha ukuba uvavanyo lwe-ANA yinxalenye enye nje yokuxilongwa. Ugqirha wakho uza kufikelela kwisigqibo sokugqibela ngokudibanisa iimpawu zakho, uvavanyo lomzimba , kunye nezinye iimvavanyo ukuba kuyimfuneko.
| Iimeko zonyango ezinokuchaphazela iziphumo ze-ANA | |
|---|---|
| Izifo ezihlala zinika iziphumo ezilungileyo ze-ANA (Izifo eziZikhuselayo) | |
| |
| Ezinye iimeko ezinokubangela iziphumo ezilungileyo ze-ANA | |
|
Ukuba uvavanyo lwe-ANA luthi luza ne-positive, kuza kwenzeka ntoni emva koko?
Xa uvavanyo lwe-ANA lubonisa ukuba lukhona, ugqirha wakho uya kwenza uvavanyo lwegazi olukhethekileyo ukuze afumanise ukuba loluphi kanye kanye uhlobo lwesifo sokuzikhusela komzimba esihambelana neempawu zakho. Uvavanyo lwe-ANA luthi kuphela "kusenokubakho ingxaki." Uhlobo oluchanekileyo lwaloo ngxaki lumiselwa kuvavanyo olongezelelweyo olufana nolu.
- Uvavanyo lwe-Anti-dsDNA: Olu luvavanyo olusetyenziselwa ngokukodwa ukuxilonga i-lupus.
- Uvavanyo lwe-anti-centromere: Oku kunceda ekuxilongeni i-scleroderma.
- Iphaneli ye-ENA: Oku kujonga iintlobo ezahlukeneyo zee-autoantibodies ngaxeshanye. Kungakunika umfanekiso ocacileyo wesifo sokuzikhusela komzimba onaso.
Ngoko ke musa ukuba namathandabuzo malunga neziphumo zakho ze-ANA. Thetha ngokukhululekileyo nogqirha wakho kwaye ucacise ukuba uza kwenza ntoni emva koko kunye nonyango omele uluthathe.
Umyalezo Wokuya Ekhaya
- Uvavanyo lwe-ANA luvavanyo olulula lwegazi olujonga iiproteni ezibizwa ngokuba yi-'autoantibodies' egazini ezihlasela imizimba yethu.
- Iziphumo zovavanyo ezibonisa ukuba unayo ayithethi ukuba unesifo rhoqo. Abantu abasempilweni nabo banokufumana esi siphumo.
- Olu vavanyo luhlobo nje lwesixhobo esisetyenziswa ngugqirha wakho ukuxilonga. Iimpawu zakho kunye nezinye iimvavanyo nazo zibalulekile.
- Ngugqirha wakho kuphela onokukunika icebiso elifanelekileyo malunga neziphumo zakho, intsingiselo yazo, kunye namanyathelo omawuwathathe ngokulandelayo, ngoko ungoyiki ukuthetha naye.
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