Kunzima kangakanani ukuzizwa sengathi awukwazi ukulawula umzimba wakho? Cabanga nje, lapho ukhuluma, udla, noma uzama ukusayina idokhumenti, ubuso bakho, izitho zomzimba, noma ezinye izingxenye zomzimba wakho ziqala ukudikiza nokudikiza ngokungalawuleki... Lokhu kuyisiphazamiso esikhulu empilweni yakho yansuku zonke futhi kungakwenza wesabe nokubhekana nomphakathi. Kulesi sihloko, sizokhuluma ngomuthi ongasiza labo abahlushwa ukunyakaza okungalawuleki okunjalo.
Izimo ezimbili eziyinhloko zezokwelapha ezibangela lokhu kunyakaza okungalawuleki yilezi:
Umuthi i-Austedo usetshenziswa kakhulu ukwelapha izifo ezimbili. Ake sibheke ukuthi ziyini.
1. I-Chorea ebangelwa yisifo sikaHuntington: Nakuba lokhu kungase kuzwakale njengegama eliyinkimbinkimbi, ngamafuphi, kuyisimo esizuzwa njengefa. Kulokhu, amangqamuzana ezinzwa ebuchosheni ayabhujiswa kancane kancane. Lokhu kubangela izinkinga ngokucabanga, ukulawula imizwa, kanye nokunyakaza komzimba. Lokhu sikubiza ngokuthi ukunyakaza okungalawuleki, okungazelelwe, okunyakazayo, nokudlidliza, i-chorea .
2. I-Tardive Dyskinesia (TD): Lesi futhi yisimo esibangela ukunyakaza okuphindaphindiwe okungalawuleki (isib. ukudikiza, ukuthuthumela) kobuso (amehlo, umlomo), izandla, izinyawo, nezinye izingxenye zomzimba. Imbangela eyinhloko yalokhu umphumela omubi wemithi esetshenziselwa ezinye izimo ezithile, ikakhulukazi ama-antipsychotics.
I-Austedo isebenza kanjani emzimbeni?
Ubuchopho bethu bufana nesikhungo esikhulu semiyalezo. Buthumela imiyalezo emisipheni yomzimba, njengokuthi "hamba" nokuthi "yeka," ngamaseli emizwa. Izithunywa zamakhemikhali ezithwala le miyalezo zibizwa ngokuthi ama-neurotransmitters .
Cabanga ngala ma-neurotransmitter njengabantu abathumela imiyalezo. Athwala izincwadi (imiyalezo) ezivela ebuchosheni ziya emisipheni.
I-Dopamine ingenye yezithumeli ezibalulekile. Kuzo zombili izimo i-Chorea ne -Tardive Dyskinesia (TD) okukhulunywe ngazo ngenhla, lezi zithunywa ezifana ne-dopamine zithumela imiyalezo ngokweqile noma ngendlela engafanele. Lokhu kusho ukuthi imisipha ithola izimpawu eziningi kakhulu ezingadingekile ukuze "inyakaze, inyakaze." Yingakho umzimba uqala ukunyakazisa nokunyakazisa ngokungalawuleki.
Lokho okwenziwa yi-Austedo ukulawula inani lemiyalezo engadingekile ethunyelwayo. Okusho ukuthi, kusiza ukunciphisa 'ithrafikhi' kancane futhi kunciphise ukunyakaza okungadingekile.
Lomuthi kufanele usetshenziswe kanjani?
Amaphilisi e-Austedo afika ngezinhlobo ezimbili.
- Iphilisi elivamile: Udokotela wakho angase akuncome ukuthi ulithathe kanye noma kabili ngosuku.
- I-Austedo XR: Leli iphilisi 'Lokukhululwa Okunwetshiwe' . Lokhu kusho ukuthi umuthi ukhishwa emzimbeni isikhathi esingamahora. Ngakho-ke, uvame ukuthathwa kanye ngosuku.
Udokotela wakho uzokuqala ngomthamo ophansi kakhulu (umthamo wokuqala) . Ngemuva kwalokho, isonto nesonto, bazokwandisa umthamo kancane kancane uze uthole umthamo wokunakekela olawula kangcono izimpawu zakho. Ngakho-ke, kubaluleke kakhulu ukulungisa umthamo wakho njengoba udokotela wakho ekutshela.
Khumbula lezi zinto lapho uthatha umuthi:
- Amaphilisi avamile e-Austedo kufanele athathwe nokudla. Amaphilisi e-Austedo XR angathathwa nokudla noma ngaphandle kokudla.
- Ungaliphuli, ulichoboze, noma ulihlafune. Ligwinye lonke ngengilazi yamanzi.
- Uma uthatha i-Austedo XR, ungase uqaphele ukuthi elinye lamaphilisi, njengengubo esele, likhishwa esitofini sakho ngemva kokuba umuthi umuncwe ngokuphelele. Lokhu kuvamile futhi akufanele kube yimbangela yokukhathazeka.
- Uma uphuthelwa umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ophuthelwe bese uthatha umthamo wakho olandelayo ngesikhathi esijwayelekile. Ungalokothi uthathe imithamo emibili ngesikhathi esisodwa ukuze ubuyisele umthamo ophuthelwe. Uma ungaqiniseki, buza udokotela wakho.
Wazi kanjani ukuthi umuthi uyasebenza?
Kunzima ukulindela imiphumela ngokushesha. Kungathatha amasonto kuya ezinyangeni ukuthi ukunyakaza kwakho okungalawuleki kuphele. Kubalulekile ukubekezela njengoba udokotela wakho kuzothatha isikhathi ukuthola umthamo ofanele wena.
Uma uzizwa sengathi izimpawu zakho azithuthuki noma zibonakala ziba zimbi kakhulu, qiniseka ukuthi ukhuluma nodokotela wakho. Angase akwazi ukushintsha umthamo wakho noma acabangele ukwelashwa okuhlukile.
Imiphumela emibi engaba khona nokuthi ungabhekana kanjani nayo?
Njenganoma yimuphi umuthi, i-Austedo ingabangela imiphumela emibi kwabanye abantu. Kodwa-ke, akuwona wonke umuntu oyitholayo. Ithebula elingezansi libala eminye yemiphumela emibi evame kakhulu kanye nezindlela ezilula zokuyilawula.
| Umphumela Ongemuhle | Ungaphatha Kanjani? |
|---|---|
| Ukozela, ukukhathala | Gwema imisebenzi edinga ukuqapha, njengokushayela noma ukusebenzisa imishini, uze wazi kahle ukuthi umuthi uthinta kanjani wena. |
| Uhudo | Ukuze uvimbele ukuphelelwa amanzi emzimbeni, phuza uketshezi oluningi olufana namanzi nejusi. Yidla ukudla okufana nobhanana, ilayisi, nesinkwa. Uma kukubi kakhulu, tshela udokotela wakho. |
| Umlomo Owomile | Phuza amanzi amaningi njalo. Zama ukuphefumula ngamakhala akho esikhundleni sokuphefumula ngomlomo wakho. Ukuhlafuna itshungama engenashukela nakho kungasiza. |
| Ubunzima Bokulala | Gwema ukuphuza iziphuzo ezine-caffeine njengekhofi netiye kusihlwa. Zibekele isikhathi esithile sokulala. Nciphisa ukusebenzisa ifoni yakho nethebhulethi ngaphambi kokulala. |
| Izifo zekhala noma zomphimbo (njengomkhuhlane) | Lokhu kuvame ukunyamalala ezinsukwini ezimbalwa. Ukuphuza uketshezi olufudumele nokuphumula kungasiza. Uma izimpawu zinkulu noma ziqhubeka, tshela udokotela wakho. |
Eminye imithi engahambisani nalo muthi (Ukusebenzisana Kwezidakamizwa)
Lena yingxenye ebaluleke kakhulu . Uma uthatha i-Austedo, kunemithi okungafanele ithathwe nayo futhi okufanele ithathwe ngokuqapha okukhulu.
Imithi okungafanele ithathwe:
- Ama-MAOI (ama-Monoamine Oxidase Inhibitors): Lawa uhlobo lomuthi olunikezwa ukucindezeleka noma isifo sikaParkinson.
- I-Reserpine: Umuthi omdala osetshenziselwa umfutho wegazi ophakeme.
- I-Tetrabenazine ne-Valbenazine: Lena futhi eminye imithi esetshenziselwa ukwelapha izinkinga zokunyakaza, njenge-Austedo. Ukuyithatha kanyekanye kungandisa ingozi yemiphumela emibi kakhulu.
Imithi okufanele ithathwe ngokucophelela:
- Ama-inhibitor e-CYP2D6: Lona uyinkimbinkimbi kakhulu. Kalula nje, ukuthatha i-Austedo kanye nemithi yokucindezeleka efana ne-bupropion kanye ne-fluoxetine, noma imithi yesigqi senhliziyo efana ne-quinidine kungakhuphula izinga le-Austedo egazini lakho futhi kwandise ingozi yakho yemiphumela emibi. Uma uthatha omunye wale mithi, udokotela wakho angase ehlise umthamo wakho we-Austedo.
- Ama-antipsychotics (imithi yokugula ngengqondo): Uma ethathwa nge-Austedo, lawa angandisa ingozi yezimo ezifana ne-Parkinsonism, ukuqina kwemisipha (i-neuroleptic malignant syndrome), kanye nokungaphumuli (i-akathisia).
- Eminye imithi ebangela ukozela notshwala: I-Austedo ingabangela ukozela. Ngakho-ke, ukuyithatha kanye nemithi yokungezwani komzimba njenge-Benadryl noma eminye imithi ebangela ukozela kungandisa ukozela. Gwema ukuphuza utshwala ngokuphelele ngenkathi usebenzisa i-Austedo.
Ngakho-ke, kubalulekile ukwazisa udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi imithi yezinye izimo, amavithamini, ngisho nemithi yendabuko).
Umlayezo Wokuya Nawe Ekhaya
- I-Austedo umuthi othize osetshenziselwa ukwelapha ukunyakaza okungalawuleki okubangelwa yisifo sikaHuntington kanye ne-Tardive Dyskinesia (TD).
- Lo muthi kufanele uthathwe kuphela ngeseluleko sikadokotela. Landela umthamo njengoba nje udokotela wakho ewushilo. Gwema ukushintsha noma ukuyeka umthamo ngokwakho.
- Sicela ubekezele ngokwelashwa njengoba kungathatha amasonto noma izinyanga eziningana ukubona imiphumela.
- Kubaluleke kakhulu ukwazisa udokotela wakho ngayo yonke eminye imithi, amavithamini, kanye nezithasiselo ozithathayo.
- Uma kuvela imiphumela emibi kakhulu, izimpawu ziba zimbi kakhulu, noma unezinkinga ngalo muthi, khuluma nodokotela wakho ngokushesha.
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