So wowɔ nsɛmmisa bi fa ENA Panel (Extractable Nuclear Antigen Panel) mogya mu nhwehwɛmu no ho? Momma yɛnkasa tiawa!

So woate pɛn sɛ yɛn ankasa nipadua ahobammɔ nhyehyɛe, asraafo a wɔkyerɛ sɛ wɔbɔ yɛn ho ban fi nyarewa ho no di mfomso na wofi ase tow hyɛ yɛn ankasa akwaa a ɛte apɔw so? Eyi ne nea yɛfrɛ no nyarewa a nipadua no tumi ko tia nyarewa . Wɔ tebea horow a ɛtete saa mu no, mogya mu nhwehwɛmu titiriw bi a wɔfrɛ no ENA panel betumi aboa wo ma woahu nea ɛyɛ ɔhaw no ankasa ne nea enti a eyi rekɔ so. Enti ɛnnɛ, momma yɛnka ENA Panel , a egyina hɔ ma Extractable Nuclear Antigen Panel , ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw so a wubetumi ate ase, okay?

Dɛn ankasa ne ENA sɔhwɛ?

Sɛ yɛbɛka no tiawa a, ENA panel no yɛ mogya mu nhwehwɛmu. Ɛhwɛ sɛ ebia yɛn nipadua mu tumi a ɛko tia nyarewa no rebɔ mmɔden sɛ ɛbɛtow ahyɛ yɛn ankasa nipadua no afã horow a ɛwɔ apɔwmuden so anaa. Afei momma yɛnkyerɛkyerɛ eyi mu kakra. Yɛn nipadua mu tumi a ɛko tia nyarewa no te sɛ asraafo dɔm a wɔbɔ ɔman bi ho ban. Wɔ saa asraafo dɔm yi mu no, asraafo titiriw bi wɔ hɔ, a yɛfrɛ wɔn antibodies . Adwuma a nnuru a ɛko tia nyarewa yi yɛ ne sɛ wobehu ɔyare mmoawa , te sɛ mmoawa ne mmoawa, a wɔhyɛn nipadua no mu na wɔko tia. Ɔtamfo biara wɔ agyiraehyɛde soronko bi wɔ ne nipadua so a ebetumi ahu no, na yɛfrɛ no antigen wɔ nnuruyɛ mu. Enti nnuru a ɛko tia nyarewa hu saa antigen yi na ɛtow hyɛ ɔtamfo no so. Ɛyɛ nhyehyɛe a nyansa wom yiye, ɛnte saa? Nanso, ɛtɔ mmere bi a nhyehyɛe a nyansa wom yi di mfomso ketewaa bi. Saa na ɛba wɔ tebea horow a wɔfrɛ no nyarewa a nipadua no tumi ko tia nyarewa mu . Nea ɛba saa bere no ne sɛ yɛn ankasa nipadua mu nkwammoaa a ɛko tia nyarewa no fi ase hyehyɛ tia protein asinasin pɔtee bi (a wɔfrɛ no extractable nuclear antigens , a ɛkyerɛ "antigens a wobetumi atew afi nuklea no mu") a wohu wɔ nkwammoaa a ɛte apɔw mu wɔ yɛn ankasa nipadua mu no nucleus (nkwaboaa no mfinimfini) mu. Ɛte sɛ yɛn ankasa asraafo a wɔreto ahyɛ yɛn ankasa ɔman mma a wɔwɔ apɔwmuden so. Wɔ bere a ɛte saa mu no, ENA sɔhwɛ no boa ma yehu yɛn ankasa antigens no mu nea saa antibodies yi reto ahyɛ so. Eyi betumi aboa nnuruyɛfo ma wɔasusuw yare a nipadua no tumi ko tia nyarewa ko a wowɔ anaasɛ wɔasi so dua sɛ wunni yare a ɛte saa.

Bere bɛn na ɛsɛ sɛ meyɛ ENA sɔhwɛ?

Ɛnyɛ obiara na ɛho behia sɛ ɔyɛ saa ENA sɔhwɛ yi. Tebea ahorow pii wɔ hɔ a oduruyɛfo betumi ahyɛ sɛ wɔbɛyɛ nhwehwɛmu yi:

• Sɛ wowɔ yare bi a nipadua no tumi ko tia nyarewa ho sɛnkyerɛnne (e.g., nkwaa mu yaw , ɔbrɛ a emu yɛ den , honam ani haw) na woayɛ Antinuclear Antibody test (ANA) a ɛyɛ papa a . ANA sɔhwɛ no yɛ sɔhwɛ a wɔde hwehwɛ nyarewa a nipadua no tumi ko tia nyarewa .Sɔhwɛ titiriw a wɔde hu. Sɛ ɛyɛ papa a, ENA nhwehwɛmu no bɛboa ma wɔakɔ so ahwehwɛ nea ɛbɛba akyi no mu.
• Sɛ woanyinsɛn na wɔadi kan ahu sɛ wowɔ lupus a . Saa bere yi de, wo nipadua mu nkwammoaa a ɛko tia nyarewa no betumi atwa awotwaa no mu akɔ wo ba no mu na ama wanya tebea bi a wɔfrɛ no neonatal lupus . Eyi betumi de nsɛnnennen aba akokoaa no so, te sɛ koma a ɛyɛ den , enti ebia wo duruyɛfo bɛkamfo akyerɛ sɛ wɔnyɛ ENA nhwehwɛmu mfa nhwɛ eyi.

Nyarewa bɛn na ENA nhwehwɛmu no bɔ mmɔden sɛ ebehu?

Nnuru a ɛko tia nyarewa ahorow pii wɔ hɔ a ENA sɔhwɛ no hwehwɛ. Saa nnuru a ɛko tia nyarewa yi ne yare biara a nipadua no tumi ko tia nyarewa no wɔ abusuabɔ pɔtee. Nyarewa a ɛtaa ba a nhwehwɛmu yi hwehwɛ ne:

• Lupus (Lupus a ɛyɛ nhyehyɛe a ɛma mogya tu /SLE) .
• Sjögren yare a ɛma obi nya ɔyare no
• Ntini a ɛka bom a wɔadi afra (MCTD) .
• Scleroderma/nhyehyɛe mu akisikuru
• Polymyositis a ɛwɔ nipadua no mu
• Dermatomyositis a ɛwɔ nipadua no mu

Saa nyarewa yi mu biara de sɛnkyerɛnne ahorow ba, enti oduruyɛfo no de wo sɛnkyerɛnne ahorow no bɛtoto nea efi ENA nhwehwɛmu no mu aba no ho na ama wanya asɛm bi.

Ɔkwan bɛn so na wɔyɛ ENA sɔhwɛ no? Ɔkwan bɛn so na ɛyɛ adwuma?

Ɛyɛ mmerɛw yiye. Lab technician bi fa mogya ketewaa bi fi ntini bi a ɛwɔ wo basa mu mu. Afei wɔde saa mogya yi yɛ ENA nhwehwɛmu no. Wɔ lab no, wɔde agyiraehyɛde soronko di dwuma . Saa agyiraehyɛde ahorow yi bata nnuru a ɛko tia nyarewa a wɔrehwehwɛ no ho sɛ ɛwɔ hɔ a. Afei saa agyiraehyɛde ahorow yi " hyerɛn" anaasɛ ɛsakra kɔla. Saa na nnuruyɛfo no tumi hu pɛpɛɛpɛ sɛ ebia saa nnuru a ɛko tia nyarewa yi wɔ hɔ anaasɛ enni hɔ. Mfiridwuma a ɛkɔ anim yiye, ɛnte saa?

Nnuru a ɛko tia nyarewa ahorow bɛn na ENA nhwehwɛmu no hwehwɛ?

Mpɛn pii no, ENA sɔhwɛ hwehwɛ nnuru a ɛko tia nyarewa a ɛyɛ adwuma wɔ antigens pɔtee anan kosi asia a wohu wɔ yɛn nkwammoaa mu no ho. Saa nnuru a ɛko tia nyarewa yi mu biara ne nyarewa bi a nipadua no tumi ko tia nyarewa ne tebea afoforo wɔ abusuabɔ. Sɛ nhwɛso no, nnuru bi a ɛko tia nyarewa ne lupus wɔ abusuabɔ.Ebinom fa yare no ho pɔtee kɛse, bere a afoforo nso ne Sjögren yare no wɔ abusuabɔ kɛse . Ɛno nti na sɔhwɛ yi ho hia na ama wɔahu yare no. Wo duruyɛfo begyina wo sɛnkyerɛnne ahorow so asi nnuru a ɛko tia nyarewa a ɛsɛ sɛ wode w’adwene si so ho gyinae.

So ɛsɛ sɛ midi kan siesie me ho ma ENA sɔhwɛ no?

Eyi ne asɛmpa a eye sen biara! Ɛho nhia sɛ woyɛ ahosiesie titiriw biara ansa na woakɔ ENA sɔhwɛ no. Wubetumi adidi na woanom sɛnea ɛsɛ na woanom wo nnuru. Ɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa afa ho na ama woanya awerɛhyem.

Dɛn na ɛsɛ sɛ yɛhwɛ kwan bere a woreyɛ ENA sɔhwɛ no?

Sɛnea yɛadi kan aka no, oduruyɛfo, ɔyarehwɛfo, anaa aduruyɛdan mu mfiridwumayɛfo de ade ketewaa bi bedi dwuma de agye mogya kakraa bi afi ntini bi a ɛwɔ wo nsa mu no mu. Ebia wobɛte ɛyaw bi anaa wo ho nyɛ wo dɛ bere a wɔde ade no hyɛ mu na woyi fi mu no. Eyi bɛkyɛ sikɔne kakraa bi pɛ. Sɛ wusuro nnade a, ebia ɛbɛboa sɛ wobɛtwe w’ani afi baabi foforo wɔ saa bere yi mu. Afei wɔde mogya no bɛkɔ aduruyɛdan bi mu akɔyɛ nhwehwɛmu.

Asiane bɛn na ɛwɔ ENA nhwehwɛmu mu?

Asiane a ɛwɔ ENA nhwehwɛmu mu no sua koraa , nanso nneɛma nketenkete betumi asi bere a wɔtwe mogya no.

• Ɛtɔ mmere bi a, sɛ ɛyɛ den sɛ wubenya ntini bi a, ebia ɛsɛ sɛ wobɔ ade no mu mpɛn pii. Ɛno yɛ nea ɛnyɛ mmerɛw kakra.
• Ebia wobɛte nka sɛ wo ho ayɛ wo yaw kakra anaasɛ wobɛtotɔ piti bere a wɔretwe wo mogya no.
• Ebia akuru kɛse bi anaa mogya a wɔaboaboa ano wɔ honam ani baabi a wɔde ade no hyɛɛ mu no ase (wɔfrɛ eyi hematoma ).
• Ɛntaa mma koraa sɛ ɔyare mmoawa betumi aba wɔ baabi a wɔabɔ no.
• Nnipa binom betumi anya mogya mmoroso bere tiaa bi bere a wɔatwe mogya awie no.

Sɛ biribi te sɛ eyi si a, mma wo ho nnyɛ wo hu, bɔ nnuruyɛfo no amanneɛ kɛkɛ.

Wobɛyɛ dɛn anya ENA sɔhwɛ bi mu aba? Dɛn na wɔkyerɛ?

Mpɛn pii no, nea efi sɔhwɛ mu ba no yɛ nea enye , papa , anaasɛ ɔhye so (a wɔsan frɛ no adwenem naayɛ) . Nneɛma a ɛkɔ so daa no betumi ayɛ soronko kakra a egyina aduruyɛdan a ɛyɛ nhwehwɛmu no so. Enti, ɛsɛ sɛ wo nhwehwɛmu amanneɛbɔ no de nea efii mu bae no ka nea wɔde yɛ nhwehwɛmu wɔ aduruyɛdan no mu no ho .

• Nea efii mu bae pa kyerɛ sɛ wohuu antibody a ɛfa ho no wɔ wo mogya mu.
• Nea efii mu bae a enye kyerɛ sɛ na nnuru a ekum ɔyare mmoawa a ɛfa ho no nni wo mogya mu, anaasɛ na kakraa bi pɛ na ɛwɔ hɔ.

Sɛ ENA nhwehwɛmu no yɛ papa a, so ɛno kyerɛ sɛ mewɔ lupus?

Dabi, wuntumi nka sɛ wowɔ yare pɔtee bi te sɛ lupus mfi nhwehwɛmu biako mu aba kɛkɛ mu.

Eyi ho hia paa. ENA nhwehwɛmu a ɛkyerɛ sɛ wowɔ lupus . Sɛ nhwɛso no, nnipa pii a wɔwɔ Sjögren yare no mu nhwehwɛmu hu sɛ wɔwɔ nnuru a ɛko tia nyarewa a wɔfrɛ no anti-SSA ne anti-SSB . Nanso, saa nnuru a ɛko tia nyarewa koro yi nso betumi ayɛ papa wɔ obi a ɔwɔ lupus anaa tebea foforo mu. Enti, wo duruyɛfo no bɛfa ENA nhwehwɛmu no mu aba, wo sɛnkyerɛnne ahorow, ne nhwehwɛmu afoforo a efii mu bae (te sɛ ANA nhwehwɛmu, CRP, ESR) abom de ahu sɛ wowɔ yare no .

Bere bɛn na ɛsɛ sɛ mesan kɔ me duruyɛfo nkyɛn bio?

Sɛ wowɔ nsɛmmisa anaa nsɛm bi a ɛhaw wo wɔ wo nhwehwɛmu no mu aba ho a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa. Afei nso, sɛ wote ɛyaw, wo ho wosow, wo ho ayɛ wo hyew wɔ baabi a wotwe mogya no, anaasɛ wowɔ ɔyare mmoawa ho sɛnkyerɛnne te sɛ atiridiinini a, kɔ baabi a wɔhwɛ wɔn a wɔwɔ yare a egye ntɛmpɛ (ETU) ntɛm ara.

Nsonsonoe bɛn na ɛda ANA sɔhwɛ ne ENA sɔhwɛ ntam?

Eyi nso yɛ ɔhaw ma nnipa pii. Ma yɛnhwɛ nsonsonoe a ɛda abien no ntam. Fa no sɛ ANA sɔhwɛ no yɛ sɔhwɛ a edi kan a polisifo taa yɛ. "So biribi anyɛ yiye wɔ ha, so autoimmune haw bi wɔ hɔ?" Mpɛn pii no, wɔhwɛ mu. Eyi kyerɛ sɛ ebia nnuru a ɛko tia nuklea (antibody a ɛko tia nkwammoaa nucleus) wɔ wo mogya mu ne dodow a ɛwɔ wo mogya mu. ENA sɔhwɛ no te sɛ sɔhwɛ titiriw bi a wɔyɛ wɔ ɛno akyi. Sɛ ANA no yɛ papa a, wɔhwɛ mu kɔ akyiri na wobisa sɛ, "Okay, sɛ biribi anyɛ yiye a, dɛn ankasa ne? Protein (antigen) pɔtee bɛn na ɛwɔ yɛn nipadua mu a wɔyɛ saa antibodies yi tia?" Ɛne sɛ, ENA sɔhwɛ no yɛ pɔtee sen ANA sɔhwɛ no. Nnipa pii a wɔwɔ nyarewa a nipadua no tumi ko tia nyarewa no wɔ ANA nhwehwɛmu a ɛkyerɛ sɛ ɛyɛ papa. Nanso, ɛtɔ mmere bi a nnipa a wɔwɔ apɔwmuden a wonni nyarewa biara a nipadua no tumi ko tia nyarewa no betumi ayɛ ANA nhwehwɛmu a ɛkyerɛ sɛ ɛyɛ papa (ENA nhwehwɛmu no taa yɛ nea ɛkyerɛ sɛ nipadua no mu nkwammoaa a ɛko tia nyarewa nni nnipa a wɔte saa mu). Ɛno nti na nnuruyɛfo hyɛ sɛ wɔnyɛ ENA nhwehwɛmu na ama wɔanya yare bi a nipadua no tumi ko tia nyarewa ho nsɛm pii wɔ obi a ɔwɔ ANA nhwehwɛmu a ɛkyerɛ sɛ ɔwɔ ANA mu no ho.

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

ENA panel (Extractable Nuclear Antigen panel) yɛ sɔhwɛ a ɛho hia a ɛma wo duruyɛfo nya nsɛm pii fa nnuru a ɛko tia nyarewa a ɛresɛe w’ankasa nkwammoaa na ebia ɛde wo sɛnkyerɛnne ahorow no ho.

Nhwehwɛmu biako biara nni hɔ a ebetumi ahu yare bi a nipadua no tumi ko tia nyarewa.

Wo duruyɛfo no bɛka ENA aba, wo sɛnkyerɛnne ahorow, ne nhwehwɛmu afoforo abom na ama wɔahu yare no pɛpɛɛpɛ. Enti, sɛ wowɔ nsɛmmisa bi fa wo nhwehwɛmu no mu aba anaa sɛnea ebetumi aka w’akwahosan ho gyinaesi ahorow ho a, nsuro sɛ wubebisa wo duruyɛfo. Afei wo nso wubetumi anya ntease a emu da hɔ. ENA nhwehwɛmu, nyarewa a nipadua no tumi ko tia nyarewa, antibodies, antigens, lupus, mogya mu nhwehwɛmu, ANA nhwehwɛmu