Sɛ wo anaa obi a ɔbɛn wo wɔ adwenemhaw, anaa sɛnea yɛn nyinaa nim no, adwenemhaw a, ebia woate nnuru a wɔkyerɛw ma no ho asɛm. Ɛnnɛ yɛrebɛka nnuru kuw biako a ɛte saa, a akyɛ kakra, nanso ɛwɔ tumi kɛse a wɔfrɛ no Monoamine Oxidase Inhibitors , anaasɛ MAOIs tiawa ho asɛm. Ɛwom sɛ wɔntaa mfa nnuru yi nni dwuma bio de, nanso nnuruyɛfo da so ara kamfo kyerɛ wɔ nsɛm titiriw bi mu. Enti ɛho hia paa sɛ wubehu nea wɔyɛ ankasa.
Sɛ yɛbɛka no tiawa a, dɛn ne MAOI yi?
MAOI yɛ nnuru kuw bi a wɔde sa adwenemhaw. Nnuru abɔfo titiriw bi wɔ amemene no mu a ɛhwɛ yɛn adwene so, kyerɛ sɛ, ɛma yɛn ani gye na yɛma yɛn ho dwo yɛn. Yɛfrɛ eyinom neurotransmitters. Ebia woate din te sɛ serotonin, dopamine, ne norepinephrine . Eyinom ne saa abɔfo no.
Seesei, wɔ yɛn amemene mu no, yɛwɔ enzyme bi a wɔfrɛ no Monoamine Oxidase. Ɛte sɛ amemene mu aduru, saa enzyme yi yi saa abɔfo no fi hɔ. Wɔ obi a ɔwɔ adwenemhaw mu no, saa abɔfo yi dodow betumi ayɛ nea ɛba fam wɔ amemene no mu.
Enti nea MAOI nnuru yɛ ne sɛ egyae saa enzyme a wɔde tew nneɛma ho no adwuma. Afei saa abɔfo a wɔwɔ anigye ( neurotransmitters ) no tra amemene no mu kyɛ na wɔyɛ wɔn adwuma yiye. Eyi ne nea ɛma adwenemhaw ho sɛnkyerɛnne so tew nkakrankakra.
Nnuru afoforo bi a ɛka saa kuw yi ho ne:
- Isocarboxazid (Marplan) a ɛwɔ nipadua no mu.
- Phenelzine (Nardil) a wɔde yɛ aduru .
- Selegiline (Emsam) a ɛwɔ nipadua no mu.
- Tranylcypromine (Nneɛma a ɛwɔ nipadua no mu) .
Te sɛ nnuru afoforo a wɔde kum adwenemhaw , saa MAOI aduru yi gye adapɛn kakraa bi ansa na ayɛ adwuma. Saa bere no mu no, ebia wo duruyɛfo bɛkyerɛw nnuru afoforo a ɛbɛboa ma woadi wo dadwen ne nna a wuntumi nna so.
Nea ɛho hia paa ne sɛ , ɛsɛ sɛ wohwɛ yiye paa wɔ nea wudi ne nea wonom ho bere a wode saa aduru yi redi dwuma no. Anyɛ saa a, ɔhaw ahorow a anibere wom betumi asɔre. Momma yɛnhwɛ saa asɛm no mu nkɔ akyiri.
Dɛn ne nsunsuanso bɔne a ɛtaa de MAOI ahorow ba?
Te sɛ nnuru biara no, eyinom betumi anya ɔhaw ahorow bi. Nanso ɛnyɛ obiara na onya ne nyinaa. Ebia nnipa binom benya biako anaa abien, na ebinom nso rennya hwee koraa. Enti nsuro sɛ wubehu eyinom. Wo ne wo duruyɛfo nka eyi ho asɛm.
| Nsunsuanso bɔne | Nkyerɛmu |
|---|---|
| Ɔhaw ahorow a ɛfa nna ho | Awia nna anaa anadwo nna a wontumi nna. |
| Adwene a ɛyɛ basaa ne obi a ɔtotɔ piti | Sɛ wote nka sɛ wo ho ayɛ wo yaw, titiriw bere a wosɔre fi tena ase no. |
| Ano a ɛyɛ kusuu ne aniwa a ɛyɛ kusuu | Ano a ɛyɛ kusuu, aniwa a ɛyɛ mmerɛw kakra. |
| Mogya mmoroso sesa | Mogya mmoroso a ɛkɔ soro anaa ɛso tew. |
| Nipadua mu nsakrae | Nipadua mu yaw, te sɛ nea anyinam ahoɔden rebɔ wo, wo mu duru a ɛkɔ soro. |
| Nnuan a wɔyam no mu haw ahorow | Akisikuru, akisikuru, anaa akisikuru. |
| Ɔbarima ne ɔbea nna ho haw ahorow | Ɔbarima ne ɔbea nna ho akɔnnɔ a ɛso tew anaasɛ ɛyɛ den sɛ obenya nna mu ɔbrasɛe. |
Nneɛma a ɛsɛ sɛ wohwɛ yiye bere a wode MAOI ahorow redi dwuma no
Eyi ne ɔfã a ɛho hia sen biara. Nneɛma bi betumi de nsunsuanso bɔne a ɛyɛ hu aba bere a wɔde ka aduru yi ho no. Enti ɛho hia paa sɛ wo ne w’abusua hu eyi.
1. Ɔhaw ahorow a ɛfa aduan ho (Aduan Nkitahodi) .
Sɛ wudi nnuan bi bere a worenom MAOI a, wo mogya mmoroso betumi akɔ soro mpofirim na asiane wom. Wɔfrɛ eyi sɛ ‘Hypertensive Crisis’. Eyi yɛ aduruyɛ mu asɛm a egye ntɛmpɛ. Enti, ɛsɛ sɛ obi a ɔnom saa aduru yiƐsɛ sɛ wudi aduan titiriw bi akyi.
Fa no sɛ wokɔɔ apontow bi ase na wonom bobesa kakra a wɔde kyiisi asinasin bi ka ho. Sɛ worenom MAOI a, saa ade ketewaa no betumi ama wo mogya mmoroso akɔ soro mpofirim akodu 200/110 a asiane wom, na anka ɛsɛ sɛ wɔde wo kɔ Dwumadibea a Ɛhwɛ Nneɛma a Egye Ntɛmpɛ So (ETU). Enti hwɛ yiye paa wɔ eyi ho.
Nnuan a ɛnsɛ sɛ wodi:
- Cheese a ayɛ dedaw: Cheese a ayɛ dedaw a wɔayam te sɛ cheddar, blue cheese, ne mozzarella.
- Nam a wɔayam: nneɛma te sɛ salami, soseji, ham.
- Wɔnom wusiw anaasɛ wɔayam: Mpataa a wɔayam no wusiw, salmon, mpataa a wɔayam, sardines.
- Nsã bi: bobesa kɔkɔɔ, beer bi.
- Soya nneɛma: soya sauce, tofu.
- Nnuaba a abere te sɛ banana ne avocado (bere a abere koraa).
Saa list yi nwie pɛyɛ. Sɛ wɔkyerɛw wo saa aduru yi a, wo duruyɛfo ne aduannuru ho ɔbenfo bɛma wo nnuan a ɛsɛ sɛ wokwati no nyinaa . Di akyi pɛpɛɛpɛ.
2. Ɔhaw ahorow a ɛwɔ nnuru afoforo ho (Drug Interactions) .
Te sɛ aduan no, nnuru bi betumi ayɛ nea asiane wom bere a wɔde ka MAOI ho no. Eyi betumi ama mogya mmoroso akɔ soro mpofirim.
Ka nnuru a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo. Nea ɛka eyi ho ne Panadol aduru a wonom ma ɛyaw, Pines aduru a wonom ma atiridiinini, Ayurvedic nnuru, nnuru a wɔde hyɛ mu, vitamin, ne nhabannuru mpo. Mfa biribiara nsie.
Titiriw no, nnuru afoforo a wɔde kum adwenemhaw, nnuru a wɔde kum ɛyaw, ne nnuru a ɛma obi ho yɛ no hyew betumi ne eyi adi nkitaho.
3. Serotonin Yare a Ɛyɛ Fɛ
Eyi yɛ tebea a ɛntaa nsi nanso ɛyɛ aniberesɛm, a ebetumi de ne nkwa ato asiane mu . Ɛba bere a serotonin dodow a ɛwɔ amemene no mu no kɔ soro ma ɛyɛ hu no. Asiane yi kɔ soro sɛ wode MAOI ne aduru foforo a ɛma serotonin dodow kɔ soro (aduru foforo a ekum adwenemhaw, aduru a wɔde kum atiridiinini, anaa nnuru bi a wɔde kum ɛyaw) a.
Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya serotonin syndrome:
- Sɛ wote nka sɛ wo ho ntɔ wo kɛse na wo ho yeraw wo
- Koma a ɛbɔ a ɛkɔ soro, mogya mmoroso a ɛkɔ soro
- Atiridiinini, akisikuru, ɔfe
- Nneɛma a enni hɔ a wohu anaa wote (Hallucinations) .
- Atiridiinini, fifiri a ɛboro so
- Sɛnea wontumi nni aduan ho akɔnnɔ so, nipadua a ɛwosow
Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, kɔ ayaresabea Emergency Treatment Unit (ETU) ntɛm ara. Sɛ ɛho hia a, wubetumi nso afrɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea hɔ akɔhwehwɛ afotu.
4. Adwene a ɛne sɛ obekum ne ho
FDA de kɔkɔbɔ ama wɔ nnuru a wɔde kum adwenemhaw nyinaa ho. Ɛne sɛ, asiane ketewaa bi wɔ hɔ sɛ wubesusuw sɛ wubekum wo ho bere a wudi kan fi ase nom nnuru yi anaasɛ bere a wɔasesa dodow a wɔde di dwuma no. Asiane yi yɛ kɛse wɔ mmerante ne mmabaa mu titiriw. Sɛ wo anaa obi a wodɔ no wɔ nsusuwii a ɛte saa a, ka kyerɛ wo duruyɛfo a ɛnkyɛ.
Nnuru a wogyae ne nyinsɛn
Ayaresa a wobegyae
MAOI nnuru a wobegyae mpofirim no yɛ asiane kɛse. Saa a wobɛyɛ no betumi ama woanya yare a ɛkyerɛ sɛ obi agyae.
- Atiridii anaa atiridiinini ho sɛnkyerɛnne te sɛ atiridiinini, nipadua mu yaw, ne fifiri
- Asoroben
- Ahomegye a wonni
- Kesereneeyɛ
- Adwene ne nneyɛe mu yare
Enti, sɛ wote nka sɛ ɛsɛ sɛ wugyae aduru no nom a, di kan ne wo duruyɛfo nkasa. Obetumi atu wo fo wɔ ɔkwan bi a wobɛfa so atew nnuru dodow so nkakrankakra na woagyae aduru no a ɛrempira w’akwahosan ho.
Wɔ nyinsɛn mu
Nsɛm kakraa bi pɛ na ɛwɔ hɔ a ɛfa ahobammɔ a ɛwɔ MAOI ahorow mu bere a wɔyem no ho. Sɛ wunyinsɛn bere a worenom aduru yi, anaasɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Mma nnnyae nnuru no nom da a wunni kan ne wo duruyɛfo nkasa.
Nkrasɛm a Wɔde Kɔ Fie
- MAOI yɛ aduru a ano yɛ den yiye a wɔde sa adwenemhaw, na ɛhwehwɛ sɛ wɔyɛ ahwɛyiye kɛse.
- Bere a worenom aduru yi no, di nnuan a wo duruyɛfo de ama wo no akyi pɛpɛɛpɛ. Kwati nneɛma te sɛ kyiisi a wɔayam, nam bi, ne nsa koraa.
- Ka nnuru afoforo a worenom nyinaa (a vitamin ne Ayurvedic nnuru ka ho) kyerɛ wo duruyɛfo .
- Sɛ wuhu serotonin yare no ho sɛnkyerɛnne te sɛ ahomegye mpofirim, koma a ɛbɔ ntɛmntɛm, ne atiridiinini a, kɔ ayaresabea ntɛm ara.
- Kwati sɛ wubegyae aduru yi mpofirim esiane biribiara nti a worenkɔ wo duruyɛfo nkyɛn.
- Nsuro sɛ wo ne wo duruyɛfo bɛkasa pefee afa nsunsuanso bɔne biara anaa ɔhaw afoforo a ebia wubehyia ho.
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