Ua hoʻonui ʻia kou mau hunaola koko ʻulaʻula? (Macrocytosis) - E ʻike kākou e pili ana i kēia!

Ua nānā anei ʻoe i kahi hōʻike hoʻāʻo koko a ʻike ʻoe ua ʻoi aku ka nui o kāu mau hunaola koko ʻulaʻula ma mua o ka maʻamau (nā hunaola koko ʻulaʻula i hoʻonui ʻia)? A i ʻole ua haʻi aku kāu kauka iā ʻoe e pili ana i kahi maʻi i kapa ʻia ʻo "Macrocytosis"? He mea weliweli iki paha kēia, akā mai hopohopo. ʻAʻole he maʻi ka Macrocytosis, he loli wale nō ia i loko o nā hunaola koko ʻulaʻula.

He aha ka Macrocytosis?

I ka ʻōlelo maʻalahi, ʻo Macrocytosis ke ʻano o ka nui o kāu mau hunaola koko ʻulaʻula ma mua o ka maʻamau. ʻAʻole kēia i manaʻo ʻia he maʻi, akā hiki ke lilo i hōʻailona o kahi mea hewa i ko mākou kino. ʻIke wale ʻia kēia ke loaʻa iā ʻoe kahi helu koko piha (CBC) / Full Blood Count ( FBC ). ʻO ka hapa pinepine, hana nā kauka i kēia hoʻāʻo `CBC` e ʻike pehea e hana ai nā hunaola o ko mākou kino a pehea lākou olakino.

Loaʻa i ka hōʻike `CBC` kahi waiwai i kapa ʻia ʻo `MCV (Mean Corpuscular Volume)`. He ana kēia o ka nui awelika o kou mau hunaola koko ʻulaʻula. Inā ʻoi aku ka waiwai `MCV` o kahi pākeke ma mua o 100 femtoliters (`100 fL`), kapa mākou i kēlā kūlana ʻo Macrocytosis.

I ka hapa nui o ka manawa, ʻaʻole kēia he pilikia koʻikoʻi. Eia nō naʻe, i kekahi manawa ʻaʻole paha e loaʻa i kēia mau hunaola koko ʻulaʻula i hoʻonui ʻia nā meaʻai a lākou e pono ai. A laila, ʻaʻole hiki i kēlā mau hunaola ke hana i kā lākou hana nui, ʻo ia hoʻi ka lawe ʻana i ka oxygen ma ke kino holoʻokoʻa. Ua kapa ʻia kēia maʻi ʻo 'Macrocytic Anemia' . Inā ʻaʻole mālama pono ʻia ʻo 'Macrocytic Anemia', hiki iā ia ke alakaʻi i nā pilikia olakino koʻikoʻi.

Pehea ka maʻamau o kēia ʻano?

Ma ke ʻano kikoʻī, ma waena o 2% a me 4% o ka heluna kanaka o ka honua he Macrocytosis. ʻO ka hapa nui o kēia poʻe, ma kahi o 60%, he Macrocytosis me ka anemia.

Eia nō naʻe, ʻoi aku ka maʻamau o ka macrocytosis me ka ʻole o ka anemia i waena o nā kamaliʻi ʻōpio a me ka poʻe ʻelemakule.

He aha nā hōʻailona o ka Macrocytosis?

ʻO ka hapa nui o ka manawa, ʻo ka hōʻailona wale nō o ka macrocytosis ʻo ia ka MCV kiʻekiʻe ma ka hōʻike CBC. ʻO ke ʻano o kēia, ʻoi aku ka nui o kāu mau hunaola koko ʻulaʻula. Inā loaʻa nā hōʻailona, ​​​​pili lākou i ke kumu kumu o nā hunaola koko ʻulaʻula i hoʻonui ʻia.

Eia kekahi laʻana, inā loaʻa iā ʻoe ka 'Macrocytic Anemia', hiki iā ʻoe ke ʻike i nā hōʻailona e like me ka nāwaliwali , ka luhi, a me ka ʻili keʻokeʻo , ʻo ia nā hōʻailona maʻamau o ka anemia. Eia kekahi, inā ʻo ke kumu he hemahema meaʻai, hiki iā ʻoe ke ʻike i nā hōʻailona e like me ka maʻi diarrhea, ka nalowale o ka hoʻomanaʻo, a me ka nalowale o ke kaulike .

ʻO ia hoʻi, ʻoiai he nui nā kumu o ka macrocytosis, hiki ke ʻokoʻa nā hōʻailona.

He aha nā kumu o ka macrocytosis?

Hoʻopuka ʻia nā hunaola koko i loko o ko kākou iwi iwi. No laila, ʻo nā pilikia i ka hana ʻana o nā hunaola koko ʻulaʻula i loko o kēia iwi iwi a me nā pilikia i ke ʻano o nā hunaola koko ʻulaʻula hiki ke hana i ka Macrocytosis. I kekahi manawa, inā he nui loa nā hunaola koko ʻulaʻula i ʻōpiopio, i kapa ʻia ʻo 'reticulocytes', i loko o kou koko, a laila hiki ke piʻi aʻe ka waiwai 'MCV'. ʻO kēia no ka mea ʻoi aku ka nui o kēia mau 'reticulocytes' ma mua o nā hunaola koko ʻulaʻula makua.

ʻO kekahi o nā kumu nui o ka macrocytosis:

Nā hemahema meaʻai

He mea nui nā meaʻai e like me ka huaora B12 a me ka folate (vitamin B9) no ko kākou kino e hana i nā hunaola koko ʻulaʻula olakino. Inā ʻaʻole lawa kēia mau meaʻai mai ka meaʻai āu e ʻai ai, a inā ʻaʻole hiki i kou kino ke omo iā lākou ma muli o kekahi maʻi, ʻaʻole e ulu pono kāu mau hunaola koko ʻulaʻula. Hiki i ka nele o ka huaora B12 a me ka folate ke hana i kahi maʻi i kapa ʻia ʻo 'Macrocytic Anemia'. No ka laʻana, ʻaʻole ʻai kekahi poʻe i nā mea kanu ʻōmaʻomaʻo a me nā huaʻai lawa. Hiki i kēia ke alakaʻi i ka nele o ka folate. Eia kekahi, hiki i ka poʻe vegan piha ke loaʻa i ka nele o ka huaora B12.

Kekahi mau lāʻau lapaʻau

Hiki ke hana ʻia ka Macrocytosis e nā lāʻau lapaʻau like ʻole. ʻO ka mea maʻamau o kēia mau mea, ʻo ia ka hydroxyurea, kahi lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi cell sickle, nā lāʻau chemotherapy like ʻole i hoʻohana ʻia e mālama i ka maʻi kanesa, a me ka antiretroviral therapy (ART) i hoʻohana ʻia e mālama i ka maʻi HIV. Inā ʻoe e lawe ana i kekahi o kēia mau lāʻau lapaʻau, e ʻike paha kāu kauka iā lākou.

Ka hoʻohana ʻana i ka waiʻona

ʻO ka inu nui ʻana i ka waiʻona kekahi kumu nui o ka Macrocytosis. Hoʻemi ka waiʻona i ka hiki o ke kino ke omo i nā meaʻai, ʻoiai nā mea e pono ai e hana i nā hunaola koko ʻulaʻula olakino.

Maʻi akepaʻa

Hiki i ka Macrocytosis ke lilo i hōʻailona o ka maʻi akepaʻa. Hoʻopili pinepine ʻia ka maʻi akepaʻa me ka hoʻohana ʻana i ka waiʻona, akā ʻaʻole mau. Eia nō naʻe, hiki ke loaʻa ka maʻi akepaʻa no nā kumu ʻē aʻe.

ʻAʻai koko hemolytic

Ma ke ʻano i kapa ʻia ʻo "anemia Hemolytic," make koke kou mau hunaola koko ʻulaʻula ma muli o kahi maʻi kumu. Ke hana ʻia kēia, hoʻokuʻu kou kino i nā "reticulocytes," (nā hunaola koko ʻulaʻula i ʻōpiopio) i loko o ke kahe koko e hoʻopiha ai i ka hemahema. ʻAʻole hiki i kēia mau hunaola koko ʻulaʻula i ʻōpiopio ke lawe i ka oxygen e like me nā hunaola koko ʻulaʻula i ʻōpiopio.

Ke kahe koko nui

Inā nalowale ʻoe i ka nui o ke koko, inā paha mai kahi ulia, ʻoki kino, a i ʻole kekahi kumu ʻē aʻe, e hoʻohui kou kino i nā reticulocytes i kou koko e uku no ka mea i nalowale. E like me ka anemia hemolytic, komo nā pūnaewele ʻōpiopio i ke koko me ka wā ʻole.

ʻO ka maʻi Myelodysplastic

He ʻano maʻi ʻaʻai kēia e ulu ana i loko o ka iwi iwi. Kāohi kēia ʻano i ka iwi iwi mai ka hana ʻana i nā hunaola koko ʻulaʻula olakino.

ʻO ka hypothyroidism

Hiki ke loaʻa ka Macrocytosis i nā poʻe me ka hypothyroidism, kahi kelepa thyroid hana ʻole. Hiki ke loaʻa me ka anemia a i ʻole me ka ʻole o ka anemia.

I kekahi manawa, ʻaʻohe kumu maopopo e loaʻa ai no ka macrocytosis, ʻoiai inā he macrocytosis wale nō kou me ka ʻole o ka anemia.

Pehea e ʻike ai inā loaʻa iā ʻoe ka macrocytosis?

E like me kā mākou i ʻōlelo ai ma mua, ʻo ka macrocytosis kahi huaʻōlelo e wehewehe ana i nā hunaola koko ʻulaʻula i hoʻonui ʻia, ʻaʻole ia he maʻi kūhelu. Inā ʻoi aku ka nui o ka waiwai MCV ma kāu hōʻike CBC ma mua o 100 fL, ʻo ia hoʻi, ʻoi aku ka nui o kāu mau hunaola koko ʻulaʻula ma mua o ka maʻamau.

I kekahi manawa hiki i nā kauka ke kuhi i ke kumu o Macrocytosis ma muli o ke koʻikoʻi o ke kūlana. No ka laʻana, inā kiʻekiʻe loa ka MCV (ma kahi o 110 - 115 fL), hiki ke lilo i hōʻailona o kahi anemia macrocytic koʻikoʻi, e like me ka anemia megaloblastic.

Nā hoʻāʻo e ʻike i ke kumu o ka macrocytosis

Inā hopohopo kāu kauka e pili ana i kou mau hunaola koko ʻulaʻula i hoʻonui ʻia, e nīnau ʻo ia iā ʻoe i nā nīnau e ʻike ai i ke kumu. Hiki iā ia ke nīnau e pili ana i kou mōʻaukala olakino, nā lāʻau lapaʻau āu e lawe ai, kāu ʻai, a me ka hoʻohana ʻana i ka waiʻona . Eia kekahi, hiki iā ia ke hana i kekahi mau hoʻokolohua ʻē aʻe:

• Ka hoʻokahe koko peripheral:Hoʻopili kēia i ka lawe ʻana i kahi hāpana o kou koko a nānā iā ia ma lalo o kahi microscope e ʻike inā he mau mea ʻē aʻe e hiki ai ke hoʻoulu i ka Macrocytosis, e like me nā pilikia me ka ulu ʻana o nā ʻula koko ʻulaʻula.
• Hoʻāʻo pae Vitamin B12 a me ka folate: Inā haʻahaʻa nā pae koko o ka vitamin B12 a i ʻole folate, ʻo ia hoʻi he hemahema meaʻai i loaʻa ʻole nā ​​​​meaʻai e pono ai e hana pono i nā hunaola koko ʻulaʻula.
• Helu Reticulocyte: Ke ana kēia hoʻāʻo i ka helu o nā hunaola koko ʻulaʻula ʻōpiopio i loko o kāu hāpana koko. Hiki i kēia ke kōkua i ka hoʻoholo ʻana inā ʻo ia ke kumu o kāu MCV kiʻekiʻe.
• Hoʻāʻo hana ate: Hoʻāʻo kēia i ka maikaʻi o ka hana a kou akepaʻa e omo i nā meaʻai e pono ai e hana i nā hunaola koko ʻulaʻula olakino.
• ʻO ka biopsy iwi: Hiki ke hana ʻia kēia hoʻāʻo inā manaʻo kāu kauka he maʻi kou e hoʻopilikia nei i ka hana ʻana o kāu mau cell koko ʻulaʻula. Pili kēia i ka lawe ʻana i kahi hāpana liʻiliʻi o kou iwi a me ka nānā ʻana i nā cell ma lalo o kahi microscope e ʻike inā he mau mea ʻē.

Pehea e mālama ai ka Macrocytosis?

Inā ʻaʻohe ou hōʻailona o ka anemia, a ʻaʻole hōʻike nā hopena o kāu hoʻāʻo i nā mea ʻē aʻe, ʻaʻole paha ʻoe e pono i kekahi lāʻau lapaʻau. A i ʻole, e hilinaʻi ka lāʻau lapaʻau i ke kumu o kou helu koko ʻulaʻula kiʻekiʻe.

• Inā kumu ʻia kāu macrocytosis e kahi hemahema meaʻai, pono paha ʻoe e hoʻololi i kāu meaʻai a lawe paha i nā mea hoʻopihapiha huaora .
• Inā pili ka pilikia me ka lāʻau lapaʻau āu e lawe nei, hiki paha i kāu kauka ke hoʻololi i ka dosage a kuhikuhi paha i kahi lāʻau lapaʻau ʻē aʻe .
• Inā loaʻa iā ʻoe ka anemia koʻikoʻi me ka macrocytosis, pono paha ʻoe i kahi hoʻoili koko .

ʻO ka mea nui loa, ʻo ia ka hahai pono ʻana i ka hoʻolālā lapaʻau a kāu kauka e hāʻawi ai iā ʻoe, me ka nānā ʻole i ke kumu o kou macrocytosis.

Hiki ke ho'ōla ʻia ka Macrocytosis?

I ka hapanui o nā hihia, e hoʻohuli ʻia ka macrocytosis iā ia iho ke mālama ʻia ke kumu kumu. E nīnau i kāu kauka pehea e pili ai ka lāʻau i kou olakino.

Pehea e hoʻemi ai i ka pilikia o ka macrocytosis?

ʻAʻole paha e hiki iā mākou ke pale aku i nā mea āpau e hiki ai ke hoʻoulu i ka macrocytosis. Eia nō naʻe, hiki iā mākou ke hōʻemi i ko mākou pilikia ma ka lawe ʻana i nā hana olakino. Eia kekahi laʻana:

• ʻO ka hoʻohui ʻana i nā meaʻai waiwai i ka wikamina B12 a me ka folate - iʻa, nā huahana waiū, nā hua manu , nā lau ʻōmaʻomaʻo, a me nā cereals i hoʻoikaika ʻia - i kāu papaʻai hiki ke hōʻemi i ka pilikia o ka hoʻomohala ʻana i ka anemia macrocytic.
• He mea nui loa ia e kaupalena i ka inu ʻana i ka waiʻona .
• Eia kekahi, mai hoʻokuʻu i nā hoʻokolohua koko makahiki. Loaʻa pinepine ka Macrocytosis i ka wā o ka hoʻokolohua koko maʻamau. Hiki i ka ʻike mua a me ka mālama ʻana ke pale i ke kūlana mai ka ʻino ʻana.

He aha ka mea e hana inā ʻaʻole mālama ʻia ka macrocytosis?

ʻO ke kauka wale nō ke hoʻoholo inā he mea e hopohopo ai kāu Macrocytosis. Inā loaʻa iā ʻoe ka Macrocytosis me ka anemia, he mea nui e ʻimi i ka lāʻau lapaʻau. Inā ʻaʻole mālama ʻia, hiki i ka Macrocytic Anemia ke alakaʻi i nā pilikia olakino koʻikoʻi.

He aha kaʻu e nīnau aku ai i ke kauka?

Inā ʻike ʻoe ua ʻoi aku ka nui o kou mau hunaola koko ʻulaʻula ma mua o ka maʻamau, e hahai i ka ʻōlelo aʻo a kāu kauka no ka mea e hana ai. Hiki paha iā ʻoe ke nīnau i nā nīnau e like me:

• Pono anei au e hopohopo e pili ana i kaʻu MCV kiʻekiʻe?
• He aha nā hoʻokolohua e pono ai e ʻike i ke kumu o ka macrocytosis?
• Pono anei iaʻu e mālama i ke kumu o koʻu mau hunaola koko ʻulaʻula i hoʻonui ʻia?
• He aha nā hoʻololi o ke ʻano o ka nohona e hiki iaʻu ke hana e mālama ai i kēia kūlana Macrocytosis?

ʻO ka mea hope loa, e hoʻomanaʻo (Leka Lawe-Home)

ʻAʻole ia he kumu hopohopo mau ka Macrocytosis a i ʻole ka MCV kiʻekiʻe. No laila, mai hopohopo inā hōʻike kāu hōʻike CBC i kēia mau waiwai. E kiʻi i ke alakaʻi a kāu kauka no ka wehewehe ʻana i kāu mau hopena. Ma muli o kāu mau hopena, hiki i kāu kauka ke kuhikuhi i nā hoʻololi ʻai a i ʻole nā ​​​​​​mea hoʻohui huaora. Mai makaʻu e nīnau pehea e pili ai kāu lāʻau i kāu mau hunaola koko a me ke olakino holoʻokoʻa. ʻO ka noho olakino ka mea nui loa!