Hmuh fo thin, hnar luang chhuak, leh a chang chuan thawk harsa... Hengte hi engtiang chiahin nge a ti thinrim? Mi tam tak chuan allergy leh asthma an vei a. Chuvangin vawiin hian heng natna te control nana hman thin damdawi class thar tak tak kan sawi dawn a ni. Chungte chu ‘Leukotriene Modifiers’ an ti a.
Leukotriene Modifiers te hi eng nge ni? Engtin nge hna an thawh?
He damdawi hi kan hriatthiam hma hian kan taksaa thil thleng tlem tal i zir chiang ang u.
A awlsam zawngin, kan allergy nei thil, chu chu allergen - entirnan, leivut, pollen - kan taksaah a luh chuan kan immune system chuan a chhang let thin. He chhanna peng pakhatah hian kan taksa hian chemical ‘leukotrienes’ an tih chu a siam chhuak a ni.
He chemical, leukotriene an tih hi kan allergy leh asthma symptom tam tak siamtu a ni . Hei hi a chhan chu:
- Lung lam panna boruak kawng chu a zim a, thawk a harsa (suffocation).
- Mucus leh tui dangte hi thawkna kawng chhungah a chhuak tam zawk.
- Hnar tissue te chu a lo hring a, hnar pawh a block bawk.
Chuvangin, Leukotriene Modifiers te hian an tih chu leukotriene an tih chemical hnathawh chu a block a ni. A dik tak chuan he chemical hi taksa chhunga cell te nena inzawmna nei lo turin an veng a ni. Kawngkhar khar ang mai a ni. Tin, chu chuan a hmaa kan sawi tawh ang chi natna tibuaitute lo awm dan chu a thunun bawk. Mahse, hengte hi first line treatment an ni tlangpui lo tih hre reng ang che.
Engtin nge he damdawi hian allergy symptoms control nan a puih?
Hriselna (allergic rhinitis) natna lan chhuah dan tlangpui chu thawk hah, hnar luang, hnar luang, leh hnar khar te hi a ni. Tin, mit na tak, hring, tui (allergic conjunctivitis) leh kawr na te pawh a awm thei bawk. Heng dinhmunte tawngtute hian nunpui a harsat zia an hre chiang hle.
Zirna hrang hrangah chuan asthma vei zinga 85% vel chuan allergy symptom an nei bawk. Chu bâkah, allergy enkawl loh chuan sinusitis, rilru na fo, khuh, mut harsatna , leh sikul emaw, hnathawhna hmun emawa hnathawh ṭhat theih lohna te ang chi harsatna a thlen thei bawk.
Leukotriene modifiers, leukotrienes hnathawh tikhawlotu hian allergy hmasa lama thawk hah leh hnim hring, chubakah hun engemaw chen hnua hnar hrual (nasal congestion) control-na kawngah nasa takin a pui a ni.
He damdawi hi Asthma tan engtin nge hman ang?
Heng damdawi te hi Asthma venna leh hun rei tak chhunga venna atan an hmang ber a ni. Exercise-induced asthma venna atan pawh an tha hle.
Mahse, hei hi a pawimawh hle : He damdawi hi acute asthma attack control nan a hman theih loh . Chumi awmzia chu he damdawi ei hian Asthma a nasat em em a, thawk harsa i tih laiin a pui dawn lo tihna a ni. Chutiang hunah chuan, rang taka thawk thei, reliever inhaler i hmang tur a ni . He Leukotriene Modifier damdawi hi natna thunun theih nan a pawimawh hle.
Sri Lanka rama Leukotriene Modifiers pek chhuah tam berte chu engte nge ni?
Asthma damdawi `zafirlukast (Accolate)` leh `zileuton (Zyflo)` te hi he pawlah hian awm mah se, Sri Lanka rama damdawi hman tam ber, allergic rhinitis leh asthma te tan pawh phalsak chu `montelukast` a ni. Brand hming `Singulair` hmangin i hre mai thei.
Research-a kan hmuh angin montelukast hman tangkai dan chu hetiang hi a ni:
| Khaikhinna | Montelukast atanga result chhuak |
|---|---|
| Placebo (damdawi ni lo thil) nen chuan . | Placebo aiin symptoms a control tha zawk. |
| Loratadine (Loratadine - Claritin ang chi) nen chuan . | Loratadine nena inmil deuh deuh result a lantir a ni. |
| Hnar atanga inhaled steroids te nen | Hnar steroid spray angin nghawng chak tak a awm lo. |
Chuvangin, doctor-te chuan Leukotriene Modifier an pek hmain intranasal steroid spray hi enchhin hmasak phawt an rawt tlangpui a, an nghawng chu a chak zawk thei a ni.
Side effect a awm em?
Damdawi dang ang bawkin mi thenkhat chuan side effect an nei thei bawk. A hman tlanglawn berte chu:
- Khawsik nei ang maia inhriatna
- Lu na
- Pum a na
- Nausea emaw, luak chhuak emaw
- Hnar hnar (hnar congestion) a awm
A bik takin fimkhur tur thil!
FDA chuan damdawi `Montelukast` hmanga rilru lam hriselna lama harsatna lian tham a thlen theih dan tur vaukhânna a tichhuak a. Hengte hi a tlem hle nachungin , hriat a pawimawh hle.
He damdawi i ei lai hian nangmah emaw i fa emaw hian heng symptoms te hi i neih chuan damdawi ei kha bansan nghal la, i doctor hnenah hriattir rawh:
- Restlessness, tihbuai
- Mumang mak tak tak emaw, hlauhawm tak tak emaw
- Lungngaihna
- Mahni intihhlum tumna
Hetiang thil i hmuh chuan tihkhawtlai suh. Damdawi lam thurawn zawng nghal rawh.
He damdawi hi tuin nge hmang lo tur?
- Naupang tê: Nausen thla 12 hnuai lam asthma leh naute thla 6 hnuai lam perennial allergic rhinitis tan heng damdawi te hi a him leh him loh hriat chian a la ni lo. Chuvangin, hengte hi Doctor thurawn lo chuan naupang tê tête hnenah pek loh tur a ni.
- Nu naupai leh nau hnute pe: Naupai i nih chuan, naupai tum i nih chuan, nau hnute i pe a nih chuan he damdawi hi i ei hmain i doctor i biak hmasak phawt a ngai a ni.
He damdawi hi tablet, chewable tablet, leh granules angin a awm a. He damdawi hi a hlawkpui kim theih nan ni thum atanga kar hnih chhung pawh a ngai thei. Chuvangin ni hnih emaw ni thum emaw chhunga i dam loh vang mai maia ei kha bansan suh. Doctor-in a sawi angin a hun chhung zawng hmang rawh.
Take-Home Thuchah a ni
- Leukotriene Modifiers hi damdawi chi khat a ni a, allergy leh asthma hun rei tak enkawlna atana hman thin a ni.
- Hengte hi asthma attack na tak, rang tak leh na tak tan emergency treatment atan hman theih a ni lo.
- Sri Lanka rama damdawi hman tam ber chu
montelukasta ni . - He damdawi i ei lai hian thil danglam bik (lungngaihna, lungngaihna, mumang mak tak tak) i hmuh chuan, a bik takin rilru hriselna lamah i doctor hnenah hrilh nghal rawh.
- Damdawi dang ang bawkin hei hi damdawi lam thurawn hnuaiah chauh hman tur a ni. I doctor chuan i tana tha ber tur enkawlna a ruat ang.
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