He otinga mō ngā Polyps Ihu me te Sinusitis (CRSwNP): Akohia te maimoatanga a Dupixent

He ihu pūmau tōu? Kua ngaro te hongi me te reka? He ihu rere tonu tōu? Ehara i te makariri noa iho ēnei, engari he mate e kiia nei ko te Rhinosinusitis Mau tonu me ngā Polyps Ihu (CRSwNP) . Ahakoa he maha ngā tāngata e whiwhi ana i te whakaoranga mai i ngā rehu ihu, i ngā rongoā ā-waha rānei, he tino uaua ki ētahi tāngata te whakahaere i ō rātou tohu mā ēnei maimoatanga. Kaua e manukanuka, nā te whanaketanga o te pūtaiao hauora, kei reira ngā huarahi hou me te whai hua hei rongoā i ēnei mate. I tēnei rā ka kōrero tātou mō tētahi maimoatanga motuhake, ko Dupixent.

He pēhea te mahi a te rongoā Dupixent mō te CRSwNP?

He whakarāpopototanga noa iho, ko ngā polyp ihu he tupu iti e puta ana i runga i ngā kiriuhi mucous o ngā pēke hau (sinuses) i roto, i te taha rānei o tō tātou ihu. Ko te tino take o tēnei ko te sinusitis mau tonu . Koinei te wā e pupuhi ana, e mumura ana hoki te ihu me ngā kōhao sinus mō te neke atu i te 3 marama. Ko tēnei pupuhi tonu te take e puta ai ngā polyp.

I te nuinga o te wā, kāore ēnei polyp e puta he tohu. Engari i a rātou e tipu haere ana, ka tīmata pea rātou ki te aukati i te mahi noa o te ihu me ngā kōhao sinus. Whakaarohia he rite ki te paipa wai e mutu te rere ina mau tetahi mea ki roto.

Ko te whāinga matua o te maimoatanga i konei he whakaiti i te mumura i roto i te ihu me ngā poka o te sinus, ka whakaiti i te hūpē, ā, ka tino whakaora i ngā tohu.

Ko te matū hohe o Dupixent ko te dupilumab . Mā te aukati i ngā pūmua e rua (`interleukin-4` me te `interleukin-13`) e tuku tohu ana hei whakaoho i te pūnaha ārai mate o te tinana kia nui rawa te tauhohenga me te mumura. Ina aukatia ēnei pūmua, ka tino heke te pupuhi me te mamae o te ihu me ngā sinuses.

Ka taea e te tangata e pāngia ana e tēnei mate te whakamahi i a Dupixent?

Ko te nuinga o te hunga whai CRSwNP ka rongoātia tuatahitia ki te rehu ihu. He momo rongoā ēnei e kiia nei ko te corticosteroid. Mena kua whakamahia e koe tēnei rehu mō ētahi marama, ā, kāore anō kia ea ō tohumate, kua tae pea te wā ki te whakaaro ki tō tākuta.Tērā pea ka tohua e te tākuta he pire corticosteroid poto. Tērā pea ka hiahiatia he pokanga mō ētahi tāngata hei tango i te puku.

He kōwhiringa pai a Dupixent mō te hunga kua whakamātau i ēnei mea katoa, tae atu ki ngā rehu ihu, ngā pire, me te pokanga pea, engari kei te pāngia tonutia e ngā tohu kino. Ko te tikanga ka whakamahia hei rongoā tuarua, tuatoru rānei.

Ngā Rangahau mō te Whai Huatanga o Dupixent (Ngā Rangahau LIBERTY)

E rua ngā whakamātautau haumanu nui, ko LIBERTY te ingoa, i whakahaerehia hei whakatau i te haumaru me te whai huatanga o tēnei rongoā. I whakamahia e ngā kaiuru katoa i roto i ēnei whakamātautau he rehu ihu i ia rā engari i pāngia tonutia e ngā tohu. Hei tāpiri, 76% o rātou kua ngaro katoa, kua ngaro rānei te kakara.

I roto i ēnei rangahau, i whakaritea a Dupixent ki tētahi rongoā placebo, he rongoā i rite te āhua ki tētahi rongoā engari kāore i roto he matū hohe. I inehia ngā hua i muri i te 6 marama.

Me pēhea te whakamahinga o Dupixent?

He werohanga wai a Dupixent ka werohangahia i raro i te kiri i ia rua wiki , ko te nuinga ki te huha, ki te puku, ki te ringa o runga rānei.

Kei roto i tēnei he pene kua whakakīia, ā, ka taea e koe te wero i a koe anō ki te kāinga. Nō reira, kāore he take e manukanuka ai koe ki ngā ngira, ki ngā pūwero rānei. Engari kia mahara, mā tō tākuta, mā tō nēhi rānei koe e whakaatu tika me pēhea te wero i te tuatahi. He mea tino nui kia tino whai i aua tohutohu.

Kia pēhea te roa ka kitea ngā hua o Dupixent?

Mena ka whai hua tēnei rongoā māu, tera pea ka kite koe i tētahi whakapainga paku i roto i tō hongi i roto i te wiki tuatahi. Tērā pea ka roa ētahi wiki, kotahi, e rua rānei marama ka memeha haere ai ētahi atu tohumate, pērā i te ihu pupū .

Ngā pānga taha me ngā raruraru ki ētahi atu rongoā

Ko te pānga taha tino kitea o Dupixent ko te tauhohenga kiri i te wāhi i werohia ai . Tērā pea ka whero, ka mamae, ka pupuhi, ka maru rānei te wāhi i werohia ai. Ko te huarahi pai ki te karo i tēnei ko te huri i ngā wāhi i werohia ai. Āta karohia hoki te werohanga ki te kiri pakaru, maru, whara rānei.

Ehara i te mea ko ēnei anake ngā pānga taha ka puta. Mena kei a koe ētahi tohu e whakararuraru ana i a koe, me kōrero koe ki tō tākuta mō ēnei.

Ētahi atu rongoā me ngā kano ārai mate

• Ngā rongoā kē atu: I mua i te tīmatanga o Dupixent, he mea nui kia kōrero koe ki tō tākuta mō ngā rongoā katoa e tangohia ana e koe (ina koa ko ngā rongoā mate huango), ngā huaora, tae atu ki ngā rongoā otaota.
• Ngā kano ārai mate: Kaua ētahi "kano ārai mate ora" e hoatu i te wā e tango ana i a Dupixent. Nō reira, ki te mea kei te tata koe ki te whiwhi i ētahi kano ārai mate, me kōrero ki tō tākuta i mua i te tīmatanga o te maimoatanga.

He aha ngā whakaaro motuhake kei a koe ina tangohia a Dupixent?

Ehara a Dupixent i te rongoā e taea te hoko ngāwari mai i te whare rongoā noa. Kua whakarōpūtia hei "rongoā motuhake". Ko te tikanga ka taea anake te hoko mai i ētahi hōhipera nui, i ētahi whare rongoā motuhake rānei.

He nui te utu mō tēnei maimoatanga. Nō reira, he mea nui kia kōrero koe ki tō tākuta mō tēnei mea i mua i te tīmatanga o te maimoatanga, kia mārama hoki te mōhio ki te utu me ngā tikanga e whiwhi ai koe i tēnei maimoatanga i tō tātou whenua.