Izintso zezinye zezona zitho zibalulekileyo emzimbeni wethu. Njengesihluzo samanzi, umsebenzi ophambili wezintso kukucoca inkunkuma esegazini lethu size siyikhuphe njengomchamo . Kodwa ngamanye amaxesha le nkqubo yesihluzo ibuthathaka inokonakala. Namhlanje, siza kuthetha ngemeko enzima kancinci echaphazela izintso, kodwa esifanele siyiqaphele sonke. Yiyo leyo i-IgA Nephropathy .
Yintoni kanye kanye i-IgA Nephropathy?
Ngamafutshane, i-IgA Nephropathy yimeko apho inxalenye yenkqubo yethu yomzimba yokuzikhusela yonakalisa izintso.
Cinga ngale ndlela. I-Immunoglobulin A, okanye i-IgA ngamafutshane, luhlobo lweproteni eyenziwa yinkqubo yethu yokuzikhusela ukuze ilwe neentsholongwane emizimbeni yethu. Ngokwesiqhelo, le protein ye-IgA iyasinceda. Kodwa emzimbeni womntu one-IgA Nephropathy, ezi protein ze-IgA ziyahlangana kwaye zenze amaqhekeza amancinci. Ngokwezonyango, sizibiza ngokuba "zii-immune complexes".
Ezi protein clumps zihamba negazi kwaye zibambeke kwiifiltha ezincinci kwizintso, ezibizwa ngokuba yi-glomeruli. Ezi filtha kulapho igazi lethu licocwa khona ngokwenene. Ngoko ke xa ezo protein clumps ze-IgA zibambeke kwezi filtha, ukudumba kwenzeka kwezo ndawo, kwaye kancinci kancinci ezo filtha zibuthathaka ziqala ukonakala. Ngenxa yalo monakalo, izintso azikwazi ukucoca igazi ngokufanelekileyo. Yiloo nto siyibiza ngokuba yi-IgA Nephropathy.
Zithini iimpawu zesi sifo?
Enye yeempawu ze-IgA Nephropathy kukuba ngamanye amaxesha inokuhlala ifihliwe emzimbeni iminyaka emininzi ngaphandle kokubonisa naziphi na iimpawu . Nangona kunjalo, njengoko isifo siqhubeka, ezi mpawu zilandelayo zinokuvela:
| Uphawu | Indlela onokuziva okanye obona ngayo |
|---|---|
| Igazi kumchamo (iHematuria) | Umchamo wakho usenokubonakala upinki, ubomvu, okanye unombala we-cola. Ngamanye amaxesha oku akubonakali emehlweni kwaye kunokubonwa kuphela ngovavanyo lomchamo. |
| I-Proteinuria (iproteni kumchamo) | Ukuba ubonakala ngathi wenza igwebu elingaphezulu kunesiqhelo xa uchama, kusenokwenzeka ukuba ukhupha iproteni kunye nomchamo. |
| Ukudumba kwezandla, iinyawo nobuso (i-Edema) | Xa izintso zingakwazi ukucoca nokususa amanzi ngokufanelekileyo, loo manzi ayaqokelelana emzimbeni aze abangele ukudumba ezandleni, ezinyaweni, emaqatheni nasebusweni. |
| Igazi elonyukayo | Xa izintso zonakele, oku kunokuchaphazela indlela ezilawula ngayo uxinzelelo lwegazi, nto leyo ebangela uxinzelelo lwegazi oluphezulu. Kwabanye abantu, olu luphawu lokuqala abalubonayo. |
Kutheni oku kusenzeka? Yintoni unobangela?
Enyanisweni, akukho sizathu sicacileyo sokuba kutheni inkqubo yomzimba yokuzikhusela iziphethe ngolu hlobo kwaye iiproteni ze-IgA ziqala ukuqokelelana kwizintso. Kodwa kukho izinto ezimbalwa oogqirha abazikholelwayo:
- Impembelelo yemfuza : Esi sifo sinokungena kwiintsapho ukuya kuthi ga kwinqanaba elithile. Oku kuthetha ukuba ukuba umntu kusapho lwakho unesi sifo, nawe unokuba sengozini yokuba naso.
- Izinto ezichaphazela imeko-bume: Kukholelwa ukuba ezinye izifo, ezinje ngezifo zomqala okanye izifo zamathumbu, zinokwenza le meko ibe mandundu okanye zibangele ukuba ivele kwasekuqaleni.
Ingaba esi sifo siyingozi? Ziziphi iingxaki ezinokubakho?
I-IgA Nephropathy sisifo sezintso esingapheliyo . Oku kuthetha ukuba sikhula kancinci ngokuhamba kwexesha (ngamanye amaxesha iminyaka eli-10-20). Asinguye wonke umntu ofumana isifo sezintso esinzima. Nangona kunjalo, kwabanye abantu, umonakalo wezintso uyanda kancinci kancinci kwaye ekugqibeleni unokukhokelela kwisifo sezintso esikwinqanaba lokugqibela .
Ekubeni esi sisifo sikhula kancinci kancinci, ukubonwa kwangethuba kunye nonyango olufanelekileyo kunokunceda kakhulu ekuthinteleni iingxaki ezinzulu.
Ukuba izintso azisebenzi kakuhle, kuya kufuneka wenze i-dialysis okanye utyando lwezintso ukuze usinde. Ngoko ke, esi sifo asinto yokuthatha lula.
Iphathwa njani?
Into yokuqala ekufuneka siyiqonde kukuba izihluzi (i-glomeruli) kwizintso ezonakeleyo sesi sifo azinakulungiswa . Ke ngoko, injongo ephambili yonyango kukucothisa ukuqhubela phambili kwesi sifo nokulawula naziphi na iingxaki ezinokuvela.
Ugqirha wakho unokucebisa olunye okanye ngaphezulu kwezi ndlela zonyango zilandelayo ngokusekelwe kwimeko yakho.
Utshintsho kwindlela yokuphila
- Ukulawula uxinzelelo lwegazi oluphezulu : Le yeyona nto ibalulekileyo. Okukhona uxinzelelo luphezulu, kokukhona umonakalo kwizintso uyanda. Ke ngoko, kubalulekile ukulawula uxinzelelo ngokusebenzisa amayeza achazwe ngugqirha ngqo.
- Ukutya: Ngokuxhomekeke kwingcebiso kagqirha wakho, unokucelwa ukuba unciphise ubungakanani beproteni ekutyeni kwakho. Ukunciphisa ukutya ityuwa nako kulungile kakhulu kuxinzelelo lwegazi.
- Ukulawula ubunzima: Ukutyeba kakhulu kunokunyusa ukukhutshwa kweprotheyini kwizintso (i-proteinuria) kwaye konyuse umonakalo kwizintso. Ngoko ke, kubaluleke kakhulu ukunciphisa umzimba.
- Kuphephe ukutshaya: Ukutshaya konakalisa ngokuthe ngqo imithambo yegazi ethambileyo kwizintso. Ngoko ke, ukuba uyatshaya, kubalulekile ukuyeka ngokupheleleyo.
Amayeza
Ukongeza kwiinguqu zendlela yokuphila, ugqirha angakunika amayeza ahlukeneyo ngokuxhomekeke kubunzima besifo.
- Amayeza oxinzelelo lwegazi.
- Amayeza anjengee-steroids anciphisa ukudumba kunye nomonakalo kwizintso.
- Amayeza okunciphisa umzimba alawula ukusebenza kwenkqubo yomzimba yokuzikhusela.
- Kutshanje kungeniswe amayeza `e-biologic'.
Konke oku kumiselwa ngugqirha wakho. Ngoko ke qiniseka ukuba uthetha nogqirha wakho kwaye ulandele imiyalelo yakhe ngqo. Ukuba uneempawu okanye unamathandabuzo malunga noku, funa ingcebiso kagqirha ngokukhawuleza.
Umyalezo Wokuya Ekhaya
- I-IgA Nephropathy sisifo esingapheliyo apho inkqubo yethu yomzimba yokuzikhusela yonakalisa izintso.
- Iimpawu eziphambili ziquka ukutshintsha kombala womchamo (ubomvu/umdaka), umchamo onamagwebu, ukudumba kwamalungu omzimba, kunye noxinzelelo lwegazi oluphezulu.
- Umonakalo owenziwe kwizintso sesi sifo awunakuguqulwa. Unyango lulawula kuphela ukuqhubela phambili kwesi sifo.
- Ukulawula uxinzelelo lwegazi, ukutya ukutya okunempilo, ukulawula ubunzima bomzimba, kunye nokuphepha ukutshaya kubalulekile ekulawuleni esi sifo.
- Ukuba unayo nayiphi na kwezi mpawu okanye ungathandabuzi ngazo, ungaze uzityeshele. Bona ugqirha wakho ngokukhawuleza ukuze akunike icebiso.
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