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Okokuqala, yintoni le gene ye-MTHFR?
Cinga ngemizimba yethu njengomzi-mveliso ontsonkothileyo nomangalisayo. Lo mzi-mveliso unemiyalelo yokwenza yonke into. Le ncwadi yemiyalelo ziijini zethu. I-MTHFR ikwalijini elibaluleke kakhulu emizimbeni yethu. Umsebenzi ophambili walejini kukufundisa imizimba yethu ukuba yenze 'iproteni ye-MTHFR'. Le proteni iyimfuneko kuthi. Kuba, i-vitamin B ebizwa ngokuba yi-folate , efumaneka ekutyeni esikutyayo, iguqulwa ibe yifom esebenzayo enokusetyenziswa ngumzimba wethu. Le folate esebenzayo ibalulekile ekwenzeni izinto ezisisiseko emizimbeni yethu, njenge -DNA .Ngoko ke yintoni le "nguqu"?
Utshintsho lutshintsho oluncinci kwimiyalelo ekweli jini. Lufana notshintsho oluncinci koonobumba encwadini. Olu tshintsho lunokwenza iproteni ye-MTHFR ingasebenzi kakuhle. Oko kuthetha ukuba ayisebenzi kakuhle ne-vitamin folate. Xa le folate ingasetyenzwa kakuhle, inqanaba le-amino acid ebizwa ngokuba yi-homocysteine egazini lethu linokunyuka. Ngaphambili, oogqirha babecinga ukuba amanqanaba aphezulu e-homocysteine ayengunobangela wezifo ezininzi, ezifana nesifo sentliziyo kunye nokuqhekeka kwegazi.Nangona kunjalo, uphando olutsha ngoku lubonisa ukuba utshintsho lwe-MTHFR kunye namanqanaba aphezulu e-homocysteine azibeki mngcipheko omkhulu kwimpilo njengoko abantu abaninzi becinga.
Ziziphi iimpawu ezibangelwa lutshintsho lwe-MTHFR?
Nantsi eyona nto ibalulekileyo nethuthuzelayo. Uninzi lwabantu abane-MTHFR gene mutation abanazo iimpawu. Baphila ubomi obusempilweni nobuqhelekileyo. Abantu abaninzi abazi nokuba banayo le gene mutation. Kwiimeko ezinqabileyo kakhulu, ezinye iimpawu zinokwenzeka. Kodwa ayiqhelekanga. Nangona kunjalo, uphando luye lwabonisa ukuba abantu abane-gene mutation banokuba "nokuthambekela okuthile" ekukhuleni kweemeko ezithile zempilo. Kodwa oku akuthethi ukuba wonke umntu onolu tshintsho uza kuba nesifo.| Imeko enokwenzeka yobudlelwane | Izinto ezilula ekufuneka uzazi |
|---|---|
| Utyekelo lokuqunjelwa kwegazi (Thrombophilia) | Nangona kukho inkolelo yokuba abanye abantu banokuba nomngcipheko okhulayo wokuqhekeka kwegazi, utshintsho lwe-MTHFR lodwa aluthathwa njengonobangela oyintloko woku. |
| Iingxaki ngexesha lokukhulelwa | Nangona kuthiwa inxulumene nezinto ezifana nokuphuphuma kwesisu kunye noxinzelelo lwegazi oluphezulu, le mbono iye yaliwa kakhulu namhlanje. |
| Abantwana abaneengxaki ze-neural tube | Le yinto abantu abaninzi abayoyikayo. Kodwa le ngozi ingathintelwa phantse ngokupheleleyo ngokuthatha i-folic acid ngokufanelekileyo ngexesha lokukhulelwa. Siza kuthetha ngayo ngakumbi. |
| I-neuropathy enxulumene nesifo seswekile | Kukho inkolelo yokuba abantu abanesifo seswekile abanotshintsho lwe-MTHFR banokuba nomngcipheko okhulayo wokuba neengxaki zemithambo-luvo. |
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Check Availability →Ngaba kufuneka ndenze uvavanyo ukuze ndifumanise?
Kukho uvavanyo lwegazi ukuze kufunyanwe olu tshintsho lwemfuza. Nangona kunjalo, imibutho emikhulu yezonyango efana ne-American College of Medical Genetics ayilucebisi olu vavanyo kuluntu ngokubanzi. Kukho izizathu ezahlukeneyo zoku:- Ukungabi namsebenzi: Njengoko besitshilo ngaphambili, uninzi lwabantu abanale nguqu abanazo iingxaki zempilo. Ngoko ke nokuba uvavanyiwe kwaye ufumanise ukuba unayo, ayizukutshintsha ubomi bakho. Inokubangela ukuba woyike.
- Ukhetho olungcono: Ukuba kukho into enye ofuna ukuyijonga, linqanaba le-homocysteine egazini lakho. Luvavanyo lwegazi olulula nolungabizi kakhulu. Ukuba inqanaba lakho liphezulu, ungathetha nogqirha wakho malunga nento omawuyenze ngayo. Akunyanzelekanga ukuba uchithe imali kuvavanyo lwemfuza .
Ngaba oomama abakhulelweyo kufuneka bakoyike oku ngokwenene?
Lo ngumbuzo obaluleke kakhulu. Oomama abaninzi abakhulelweyo bayoyika xa besiva ngale MTHFR, besithi, "Owu, ngaba umntwana wam uza kuba nesiphene se-neural tube njenge-Spine Bifida?" Umyalezo ongcono onokuwunika ngulo, "Musa ukoyika konke konke." Imibutho ephambili yezonyango zabasetyhini kunye nezoogqirha eSri Lanka nakwihlabathi liphela (njenge-ACOG) ayicebisi ukuba kuvavanywe oomama abakhulelweyo olu tshintsho lwezakhi zofuzo. Kuba, akufuneki. Eyona nto ibalulekileyo kukuthatha ipilisi ye-folic acid ecetyiswa ngugqirha yonke imihla ngaphandle kokusilela ngaphambi nangexesha lokukhulelwa. Ubungakanani bee-milligrams ezinikwayo, nokuba kumama onolu tshintsho lwezakhi zofuzo lwe-MTHFR, bubonakaliswe kwihlabathi liphela ukuba banele ngokupheleleyo kuphuhliso olusempilweni lwenkqubo yemithambo-luvo yomntwana. Ke, endaweni yokukhathazeka ngovavanyo lwe-MTHFR, kubaluleke kakhulu ukulandela imiyalelo kagqirha wakho kwaye ufumane isixa esifanelekileyo se-folic acid.Ziziphi iindlela zonyango zokuguqulwa kwe-MTHFR?
Akukho mfuneko "yokunyanga" utshintsho lwe-MTHFR gene. Ayisosifo. Nangona kunjalo, ukuba uvavanyo luqinisekisa ukuba amanqanaba akho e-homocysteine aphezulu, ugqirha wakho uya kukucebisa ukuba uyilawule. Oku kudla ngokubandakanya ukwenza oku kulandelayo:- Izongezo zeFolic Acid : Ugqirha wakho uza kucebisa izongezo zefolic acid ezifanelekileyo kuwe. Basenokucebisa nezongezo zevithamini B6 kunye neB12.
- Ukutya okutyebileyo kwi-folate : Yongeza ukutya okutyebileyo kwi-folate ekutyeni kwakho.
- Imifuno eluhlaza okwesibhakabhaka efana nespinatshi, ikale, kunye nemifuno eluhlaza
- Iimbotyi ezifana neelentile, iitships, kunye neepips
- Iziqhamo ezifana neeorenji kunye neeavokhado
- Iimbotyi
Umyalezo Wokuya Ekhaya
- I-MTHFR ayisosifo. Lutshintsho nje oluqhelekileyo noluncinci olunokwenzeka kwiijini zethu.
- Uninzi lwabantu abanale nguqu alufumani zimpawu okanye iingxaki zempilo ubomi babo bonke.
- Oogqirha abacebisi ukuba kwenziwe uvavanyo olukhethekileyo lwale nto. Musa ukoyika ngokungeyomfuneko.
- Oomama abakhulelweyo akufuneki bakhathazeke ngale nto. Eyona nto ibalulekileyo kukuthatha ipilisi ye-folic acid oyinikwa ngugqirha wakho yonke imihla.
- Ukuba usenayo nayiphi na inkxalabo okanye uloyiko malunga noku, musa ukudideka ngokufunda izinto kwi-intanethi, kodwa buza ugqirha wakho wosapho omthembayo ngayo.
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