Ungase ube nelungu lomndeni, umngane, noma ngisho nawe ngokwakho olashwa umdlavuza webele . Ngezikhathi ezinjengalezi, odokotela batusa imithi ehlukahlukene. Phakathi kwayo, omunye abantu abaningi abavame ukuzwa ngawo, ikakhulukazi umdlavuza webele owenzeka ngemva kokunqamuka kokuya esikhathini, yi-Exemestane. Ungase uwazi ngegama lomkhiqizo i-Aromasin. Namuhla, sizokhuluma nje ngalo muthi, ukuthi usebenza kanjani, ukuthi usebenza kahle kangakanani, nokuthi yini okufanele uyiqaphele lapho uwusebenzisa.
I-exemestane ikunciphisa kanjani ukukhula kwamaseli omdlavuza webele?
Kalula nje, kunezinhlobo ezithile zomdlavuza webele ezisizwa ukukhula yi-hormone i-estrogen emizimbeni yethu. Lokhu yilokho esikubiza ngokuthi umdlavuza 'one-hormone-receptor-positive'. Cabanga ngamaseli omdlavuza njengesitshalo esidla 'ukudla' okubizwa ngokuthi i-estrogen.
I-Exemestane isebenza ngokuvimba ukukhiqizwa kwe-hormone ye-estrogen emzimbeni wethu. Kufana nokuvimba ukudla okuphakelwa yisitshalo. Bese amangqamuzana omdlavuza elahlekelwa izakhamzimba azidingayo ukuze akhule. Ngale ndlela, lo muthi usiza kakhulu ekuvimbeleni umdlavuza ukuthi ungabuyi.
Lokhu kuye kwafakazelwa ucwaningo. Ocwaningweni lweminyaka emi-3, abesifazane ababenomdlavuza webele ohlaselayo ngemva kokunqamuka kokuya esikhathini banikwa i-exemestane, futhi ingozi yabo yomdlavuza wokubuya yancishiswa ngo-65% uma kuqhathaniswa nabesifazane abangazange bayithole. Futhi, ngaphandle kwezimpawu ezivamile zokunqamuka kokuya esikhathini, njengokushisa okukhulu, akukho miphumela emibi emibi ebikiwe.
Ingabe ingasetshenziswa kanye neminye imithi?
Yebo, impela. Ukwelashwa komdlavuza akugcini nje emuthini owodwa. Ngezinye izikhathi kuyadingeka ukuqondisa izindlela ezahlukene zokubulala amangqamuzana omdlavuza. Yingakho odokotela behlela ukwelashwa ngokuhlanganisa imithi eminingana.
Ucwaningo lukhombisile ukuthi umuthi i-exemestane unganikezwa kanye neminye imithi efana ne -ribociclib kanye ne -everolimus (eyaziwa nangokuthi 'ukwelashwa kwe-triplet'). Le nhlanganisela yemithi inciphisa amathuba okusinda kwamangqamuzana omdlavuza futhi inciphise kakhulu ingozi yokubuya komdlavuza. Lokhu kwelashwa nakho kutholakale kuphephile kakhulu.
Ocwaningweni lwamuva nje, isiguli esineminyaka engu-48 ubudala esinomdlavuza webele esenze i-chemotherapy) Kamuva, kwanikezwa imithi emibili ebizwa ngokuthi i-Exemestane kanye ne-everolimus ndawonye. Le mithi emibili yasebenza ndawonye ukubhubhisa amangqamuzana omdlavuza nokuvimbela umdlavuza ukuthi ungabuyi. Lapho isiguli siqashwe iminyaka emi-5, akukho ukukhula komdlavuza okwabonakala emzimbeni waso. Lokhu kukhombisa ukuthi lokhu kwelashwa kuphumelela kangakanani.
Izinto okudingeka uzazi nge-Exemestane
| Iqiniso | Incazelo |
|---|---|
| Ukusetshenziswa okuyinhloko | Ukuvimbela ukuphinda kuvele umdlavuza webele one-hormone-receptor ngemuva kokunqamuka kokuya esikhathini. |
| Ukusebenza kahle | Kuvimba ukukhiqizwa kwe-hormone i-estrogen emzimbeni futhi kumise ukukhula kwamangqamuzana omdlavuza. |
| Imiphumela emibi evamile | Izimpawu ezivamile zokunqamuka kokuya esikhathini zifaka phakathi ukushisa okukhulu, ubuhlungu bamalunga, kanye nokukhathala. |
| Ngubani ongafaneleki? | Akufanelekile kwabesifazane abangakayi enkathini yokuthomba, labo abakhulelwe noma abazama ukukhulelwa, kanye nomama abancelisayo. |
Izinto ezibalulekile okufanele uzicabangele lapho uthatha lo muthi
Kunezinto ezimbalwa okufanele uziqaphele uma usebenzisa lo muthi. Lezi zibaluleke kakhulu .
Khumbula, ukwelashwa komdlavuza kuwumzamo weqembu phakathi kwakho nodokotela wakho, ngakho-ke kungcono ukuvuleleka kukho konke.
- Landela imiyalelo kadokotela ngqo: Lo muthi ungowakhoKubaluleke kakhulu ukuthatha umuthi njengoba nje udokotela wakho encoma, ngomthamo ofanele, ngesikhathi esifanele. Ungalokothi ushintshe umthamo noma uyeke ukuthatha umuthi wedwa. Uma unenkinga, khuluma nodokotela wakho ngakho.
- Izingozi uma ungakafiki esikhathini sokuthomba: Lo muthi awuvame ukunikezwa abesifazane abangakafiki esikhathini sokuthomba ngoba ungathinta ukuzala. Udokotela wakho uzoxoxa nawe ngalokhu kabanzi.
- Ungasebenzisi ngesikhathi sokukhulelwa: Ungasebenzisi lo muthi uma ukhulelwe, uzama ukukhulelwa, noma uncelisa. Kufanele futhi ugweme ukukhulelwa ngenkathi uthatha umuthi. Xhumana nodokotela wakho ukuze uthole iseluleko ngalokhu.
- Qaphela ngeminye imithi: Ungathathi eminye imithi equkethe i-estrogen (isibonelo, ukwelashwa kokufaka esikhundleni sama-hormone ) nge-Exemestane. Le mithi emibili isebenza ngokumelene, okungabangela imiphumela emibi. Uma uthatha eminye imithi, amavithamini, noma imithi yamakhambi, tshela udokotela wakho ngayo.
Umlayezo Wokuya Nawe Ekhaya
- I-Exemestane iyisidakamizwa esisebenzayo sokuvimbela ukuphinda kuvele umdlavuza webele one-hormone-receptor-positive owenzeka ngemva kokunqamuka kokuya esikhathini.
- Lokhu kusebenza ngokumisa ukukhiqizwa komzimba kwe-hormone i -estrogen , okulawula ukukhula kwamaseli omdlavuza.
- Imiphumela engcono ingatholakala ngokusebenzisa lo muthi kanye neminye imithi yokulwa nomdlavuza.
- Lo muthi akufanele uqalwe noma umiswe ngaphandle kweseluleko sikadokotela.
- Uma unemibuzo noma ukukhathazeka mayelana nalo muthi noma ukwelashwa, khuluma nodokotela wakho ngokukhululekile ngakho. Ungesabi.
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