Ama-antibiotic e-Fluoroquinolone: ​​Sazise ngqo ngezingozi nemiphumela emibi

Cishe uke wanikezwa umuthi wokulwa namagciwane wokutheleleka ngamagciwane uma uye kudokotela. Ezinye zazo zinamandla kakhulu futhi zingalapha ukutheleleka ngokushesha. Kodwa bewazi ukuthi kunemithi ethile enamandla kakhulu engaba nemiphumela emibi kakhulu? Ama-Fluoroquinolones ayiqembu lemithi esetshenziswa kuphela ezimweni ezikhethekile. Namuhla, sizoxoxa ngakho konke ngendlela elula necacile.

Ziyini lezi fluoroquinolones?

Kalula nje, lezi yiqembu lama-antibiotic asetshenziselwa ukwelapha noma ukuvimbela ukutheleleka okuthile kwamagciwane. Nakuba atholakala ngawo-1960, odokotela baqala ukuwasebenzisa kakhulu ngawo-1970 nawo-1980. Ngaleso sikhathi, le mithi yayithandwa kakhulu. Yayisebenza kahle kakhulu ekwelapheni ukutheleleka okuhlukahlukene, kusukela ekuthelelekeni komgudu womchamo kuya ku-pneumonia. Kwakulula ukuyithatha njengephilisi kanye noma kabili ngosuku, okwenza kube lula ukuyithatha. Yayidingeka kakhulu phakathi kodokotela ngoba yayinikeza usizo olusheshayo ngisho nalapho amanye ama-antibiotic engasebenzi. Kodwa-ke, inkinga yayiwukuthi abanye abantu baqala ukuzwa imiphumela emibi kakhulu evela kule mithi. Futhi, ngenxa yokuthi yayisetshenziswa ngokungadingekile kuzo zonke izifo, amanye amabhaktheriya aba namandla okumelana nale mithi (ukumelana nama-antibiotic).

Lomuthi usebenza kanjani?

Cabanga ngebhaktheriya njengomshini wokukopisha. Iqhubeka nokwenza amakhophi ayo, okwandisa inani lokutheleleka emizimbeni yethu. Ukuze yenze la makhophi, ibhaktheriya idinga ukwelula ikhodi yayo yezakhi zofuzo, okungukuthi, i-DNA yayo. Ama-enzyme akhethekile ayayisiza ukwelula le DNA. Ama-Fluoroquinolones ayamisa ama-enzyme okwelula i-DNA. Khona-ke amabhaktheriya awakwazi ukwenza amakhophi, okungukuthi, awakwazi ukuzala. Lena yindlela le mithi elawula ngayo ukusabalala kokutheleleka.

Yiziphi izifo ezisetshenziswa yi-fluoroquinolones?

Okokuqala, ake sibheke izifo ezivamile okungafanele zisetshenziswe lo muthi. Ngokuvamile, awunconywa ezimweni ezilandelayo ezingelashwa ngamanye ama-antibiotic alula:

• I- sinusitis ebukhali
• I-bronchitis ebukhali (i-bronchitis ebukhali)
• Ukutheleleka kwe-urinary tract okulula (UTIs)

Nazi ezinye zezimo lapho udokotela angase anikeze khona lo muthi:

• Ukutheleleka okuyinkimbinkimbi kwendlela yomchamo (UTIs)
• Inyumoniya
• Ukutheleleka kwe-prostate (i-Prostatitis)
• Uhudo olubangelwa amagciwane athile
• Izimo ezibucayi lapho amagciwane angena khona egazini, njenge- sepsis

Odokotela bamazinyo bangase babancomele nakwezinye izifo zamazinyo. Zisetshenziswa nakubantu abane-allergy kwamanye ama-antibiotic noma uma kungekho ezinye izinketho.

Yimiphi imithi engaphansi kweqembu le-fluoroquinolone?

Ungase ujwayelene nelinye lala magama. Lezi yizinhlobo ezivame ukusetshenziswa kakhulu ze-fluoroquinolones. Lokhu kuza ngesimo samaphilisi, imijovo ye-IV, amaconsi endlebe, kanye namaconsi amehlo.

Yimiphi imiphumela emibi kakhulu yale mithi?

Lena yingxenye ebaluleke kakhulu yalesi sihloko. Akuwona wonke umuntu onemiphumela emibi evela kuma-fluoroquinolones. Kodwa-ke, kwabanye abantu, imiphumela emibi ingaba mibi ngokwanele ukubangela umonakalo ohlala njalo. Ngakho-ke kubalulekile ukuqaphela lokhu. Eminye imiphumela emibi ingavela emahoreni ambalwa okuqala umuthi. Eminye ingavela emavikini noma ngisho nasezinyangeni ngemuva kokuyeka umuthi. Eminye yemiphumela emibi evame kakhulu futhi emibi yile:

• Izinkinga zemisipha: Imisipha, ikakhulukazi imisipha ye-Achilles ngemuva kwesithende, ingavuvukala, ibe buhlungu, noma iqhume.
• Ukulimala kwemizwa: Lokhu kubizwa ngokuthi i-peripheral neuropathy. Izimpawu zingafaka phakathi ukungazweli, ukuxhuzula, kanye nomuzwa wokuxhuzula ezithweni. Lokhu ngezinye izikhathi kungaba yinto engapheli.
• Izinkinga zempilo yengqondo: Ukukhathazeka, ukucasuka, ukudideka, ukucindezeleka, imibono engekho, ngisho nemicabango yokuzibulala ingase ivele.
• Ukulimala kwe-aorta: Lesi yisimo esingavamile kakhulu kodwa esiyingozi kakhulu. Singabangela ukudabuka noma ukuhlukana kwe-aorta (ukuhlukana kwe-aorta).
• Izinguquko emazingeni kashukela egazini: Amazinga kashukela egazini angaba phansi noma aphezulu ngendlela eyingozi kokubili kubantu abanesifo sikashukela nakubantu abanempilo.
• Kwabagulayo abane-myasthenia gravis: Ubuthakathaka bemisipha bungase bube bubi kubantu abanalesi sifo.

Wenzani uma uhlangabezana nophawu olufana nalolu?

Uma uhlangabezana nanoma yiziphi izimpawu ezilandelayo ngenkathi uthatha i-fluoroquinolone, yeka ukuthatha umuthi bese ushayela udokotela wakho ucingo ngokushesha. Uma uzwa ubuhlungu obukhulu noma ubunzima bokuphefumula, iya ekamelweni lezimo eziphuthumayo esibhedlela (ETU) ngokushesha.

• Ubuhlungu obungazelelwe, ukuvuvukala, noma ukuqina kwemisipha, amalunga, noma imisipha.
• Ukuba ndikindiki, ukuthuthumela, noma ukuzwa ukukhasa ezithweni.
• Ukukhathazeka, ukudideka, noma ushintsho esimweni sengqondo.
• Ukuzizwa unesizungu noma ukushaya kwenhliziyo okungajwayelekile.
• Uhudo oluhambisana nobuhlungu obukhulu esiswini.

Imibuzo Evame Ukubuzwa (Imibuzo Evame Ukubuzwa)

1. Ingabe ama-fluoroquinolone avinjelwe?

Cha. Le mithi isasetshenziswa. Kodwa manje inconywa kuphela ezifweni ezinkulu neziyinkimbinkimbi, hhayi izifo ezilula. Futhi, iyindlela ebalulekile kubantu abane-allergy kwamanye ama-antibiotic.

2. Ingabe iBactrim iyi-fluoroquinolone?

Cha. I-Bactrim iyinhlanganisela yama-antibiotic amabili ahlukene (i-sulfamethoxazole ne-trimethoprim). Ayiyona ingxenye yesigaba se-fluoroquinolone.

3. Ingabe i-Amoxicillin iyi-fluoroquinolone?

Cha. I-Amoxicillin iyi-antibiotic eyingxenye yeqembu le-penicillin. Akuyona i-fluoroquinolone. I-Fluoroquinolones, ama-antibiotic, i-Ciprofloxacin, i-Levofloxacin, imiphumela emibi, ukutheleleka ngamagciwane, imiphumela emibi yama-antibiotic