Ingabe imilenze yakho ivuvukele futhi isikhumba sakho sizwakala siqinile? Ake sifunde ngalokhu (i-Pretibial Myxedema)!

Wake waphawula ukuthi isikhumba semilenze yakho, ikakhulukazi ngaphansi kwamadolo, sivuvukala ngokuzumayo, sibe lukhuni, futhi ngezinye izikhathi siphenduke umbala? Noma ingabe sibukeka njengesikhumba esiphuzi kwezinye izindawo? Uma unalezi zimpawu, ungase ube nesifo esibizwa ngokuthi i-Pretibial Myxedema, esizokhuluma ngaso namuhla.

Kuyini lokhu (i-Pretibial Myxedema)? Masikuqonde kalula!

Kalula nje, i-Pretibial Myxedema, ngezinye izikhathi ebizwa ngokuthi i-Graves' Dermopathy, uhlobo lwe-Graves' Disease, isimo esithinta isikhumba sethu. Sibangelwa ukuqongelela kwama-carbohydrate noshukela, noma ngokunembile, ama-glycosaminoglycans noma ama-mucopolysaccharides, ezingqimbeni ezijulile zesikhumba sethu. Lokhu kuqongelela ikakhulukazi emilenzeni engezansi, ngaphansi kwamadolo. Yilapho imilenze ivuvukala, isikhumba siba namaqhubu, futhi isikhumba siba namaqhubu (ama-scaling plaque). Asho ukuthini amagama athi "Pretibial" kanye nelithi "Myxedema"?

• "Pretibial": Lokhu kubhekisela ethanjeni elikhulu ohlangothini lomlenze wethu ngaphansi kwedolo, ingaphambili le-`(tibia)`. Uma sikusho ngesiSinhala, kufana nokuthi "phambi kwethambo lomlenze".
• "I-Myxedema": Lokhu kusho ukuvuvukala kwezicubu ezingaphansi kwesikhumba sethu.

Ubani othinteka kakhulu yilesi simo?

(Pretibial Myxedema) Nakuba noma ubani engaba nayo, abanye abantu banamathuba amaningi okuba nayo. Yilezi:

• Abantu abaneSifo samaThuna: Lokhu yikho okukhathazayo okuyinhloko.
• Abantu abanezinkinga ze-thyroid: Lokhu kusho izimo ezifana nokuthi `(Hypothyroidism)` ( i-hormone ye-thyroid ephansi) noma `( Hyperthyroidism )` ( i-hormone ye-thyroid ephezulu).
• Abantu abanesifo samehlo esibi: Lokhu kuvame ukuhlotshaniswa nesifo samaGraves.
• Abantu abaneminyaka ephakathi kuka-40 no-60.
• Abesifazane: Lesi simo sivame kakhulu kwabesifazane kunakwabesilisa.

Cabanga nje, umakhelwane wakho, u-Anti Susila, ubelokhu enezinkinga ze-thyroid isikhathi esithile. Ngokungazelelwe, waphawula ukuthi indawo engaphansi kwamadolo emilenze yakhe yayivuvukele, isikhumba sasibomvu kancane, futhi sasizwakala sengathi amaqhubu amancane lapho ethintwa. Ekuqaleni, wacabanga ukuthi kungenzeka ukuthi kungenxa yokuzikhandla. Kodwa kwaba yilapho ekukhombisa udokotela kuphela lapho aqaphela khona ukuthi kungaba yi-Pretibial Myxedema.

Yiziphi izinhlobo eziyinhloko ze-Pretibial Myxedema?

Kunezinhlobo ezine eziyinhloko zalesi simo. Izimpawu zingase zihluke kancane ngokufanele: 1. Ukusabalalisa: Lolu uhlobo oluvame kakhulu. Lokhu kubonakala ngokuvuvukala okungenamigoqo okungavuvukali lapho isikhumba sicindezelwa esikhumbeni. 2. I-Plaque:Ngaphezu kokuvuvukala, kunezinhlayiya ezijiyile, eziphakanyisiwe, nezinoqweqwe ebusweni besikhumba. 3. Amaqhubu: Ngaphezu kokuvuvukala, kunezinhlayiya eziqinile ngaphansi kwesikhumba. 4. I-Elephantiasis: Lolu uhlobo olungavamile kakhulu. Kulolu hlobo, uketshezi lwe-lymphatic luqoqana ngaphansi kwesikhumba, okwenza isikhumba sibukeke siqinile futhi siqinile.

Ziyini izimpawu ze-(Pretibial Myxedema)? Ake sizazi kahle!

Uma unalesi simo, ungase ube nesinye noma ngaphezulu salezi zimpawu:

• Ukuvuvukala: Isikhumba emlenzeni wakho sibukeka sikhulu futhi sikhukhumele kunosuku olwandulele.
• Amaqhubu aqinile ngaphansi kwesikhumba: Lawa angazwakala uma uwathinta ngesandla sakho.
• Ezinye izindawo zesikhumba ziba nkulu futhi zibe njengezingcwecwe: njengezikali zezinhlanzi.
• Isikhumba kanye nezimbotshana zezinwele ziba nokuthungwa okucwebezelayo nokufana ne-wax: Kungase kubukeke njengekhasi le-orange .
• Umbala wesikhumba uyashintsha: ungahluka kusuka kophuzi nowolintshi kuya konsundu, obomvu, nonsomi.
• Kukhona ukujuluka okukhulu noma ukukhula kwezinwele ngokweqile ezindaweni ezithintekile.
• Isikhumba siyabuhlungu noma siyalunywa.

Ekuqaleni, lesi simo singase siqale njengeqhubu eliqinile esikhumbeni. Leli qhubu lingakhula libe likhulu ngokuhamba kwesikhathi, noma lingase lihlangane nezinye iziqhubu.

Kukuphi emzimbeni lapho lezi zimpawu zithinta khona kakhulu?

Izimpawu ezivame kakhulu ze-Pretibial Myxedema yilezi:

• Emilenzeni engezansi kwamadolo.
• Ezinyaweni.
• Imisipha endaweni yemisipha.

Ngezinye izikhathi izinguquko zobuso zingabangelwa yiSifo sikaGraves noma isifo se-thyroid, kodwa lokho kuyinkinga ehlukile.

Kungani sithola (i-Pretibial Myxedema)? Ziyini izimbangela?

Nakuba imbangela eqondile yalokhu ingakaqondakali ngokugcwele, kuvele izici eziningana ocwaningweni. Isizathu esiyinhloko salokhu ukuqongelela kwamakhemikhali kashukela `(glycosaminoglycans noma mucopolysaccharides)` esikushilo ngaphambili ezingqimbeni zesikhumba `(dermis)` kanye `(hypodermis)`. Kodwa kungani siqongelela kanjalo? 1. Inqubo yesistimu yokuzivikela `(Autoimmune response)`: Kalula nje, uhlelo lokuzivikela lomzimba wethu luqala ukusebenza ngokumelene nathi. Kulokhu, uhlelo lwethu lokuzivikela lunikeza amaseli ethu uphawu lokuthi akhiqize `(antibodies)` ngokumelene nama-hormone e-thyroid. Lawa `(antibodies)` abangela amaseli ukuthi akhiqize into ebizwa ngokuthi `(glycosaminoglycans)` ngokweqile. 2. Ukusebenza kwamaseli (T lymphocyte): `(T lymphocytes)` uhlobo olukhethekile lweseli ohlelweni lwethu lokuzivikela. Lawa maseli angena ezicutshini zesikhumba futhi akhulule amaprotheni esithunywa abizwa ngokuthi `(cytokines)`. Lawa ma-cytokines abangela amaseli ukuthi akhiqize inani elikhulu lama-glycosaminoglycans. 3. Impendulo yokulimala:Cabanga ukuthi ulimele emlenzeni wakho ongezansi, endaweni engaphambi kokubeletha. Uma une-hypothyroidism, amangqamuzana omzimba namaprotheni angaqongelela endaweni yokulimala. Lokhu kungenxa yokuthi ama-hormone e-thyroid alawula ukuqongelela kwalezi zinhlanganisela ezicutshini. Uma ama-hormone engekho, lokho kulawula kuyalahleka.

Udokotela uyixilonga kanjani i-Pretibial Myxedema?

Uma ubona udokotela, uzoqala ngokukubuza ngezimpawu zakho kanye nanoma yiziphi ezinye izimo zezokwelapha ongase ube nazo (`(umlando wezokwelapha)`). Bese bezokuhlola (`(ukuhlolwa ngokomzimba)`). Ukuqinisekisa ukuthi lokhu kuyi-(Pretibial Myxedema), udokotela angenza lezi zivivinyo ezilandelayo:

• Ukuhlolwa kwegazi: Hlola amazinga akho e-thyroid hormone.
• I-biopsy yesikhumba: Lokhu kungasetshenziswa ukuthola ukuthi ngabe lesi simo sikhona yini kanye nokukala amazinga e-glycosaminoglycans esikhumbeni.

Ingabe ikhona indlela yokwelapha lokhu? Yini engenziwa?

Esikhathini esiningi, izimpawu ze-Pretibial Myxedema ziwubuhle kuphela, ngakho-ke ukwelashwa akudingeki ngaso sonke isikhathi. Okusho ukuthi, ngokuvamile azibangeli monakalo omkhulu . Kodwa-ke, uma ungakhululekile ngokubukeka noma unezinye izimpawu (ukuluma, ubuhlungu), kunezindlela zokwelapha ezitholakalayo.

• Ukugqoka amasokisi noma amasokisi acindezelwe: Lokhu kunganciphisa ukuvuvukala.
• Okhilimu noma amafutha okugcoba: Vimbela ukulunywa nokuvuvukala.
• Imithi kanye nemijovo yomlomo kanye neyesikhumba: Ukunciphisa amaqhubu ngaphansi kwesikhumba noma ukunciphisa izinguquko ekubukekeni.
• Ukwelapha Isifo Sama-Graves noma Isimo Se-thyroid: Lena yinto ebaluleke kakhulu . Uma imbangela eyisisekelo yelashwa, izimpawu ze-Pretibial Myxedema zivame ukuthuthuka.
• I-Plasmapheresis: Lokhu kuyindlela yokwelapha eyinkimbinkimbi kancane. Kuhilela ukususa ingxenye ewuketshezi yegazi (i-plasma), ukufaka esikhundleni samangqamuzana egazi abomvu namhlophe nama-platelet kusisombululo esisha, bese uwabuyisela emzimbeni. Lokhu akuyona into wonke umuntu angayenza.

Okubalulekile: Nakuba ukuhlinzwa kungasusa amaqhubu angaphansi kwesikhumba, ngokuvamile akukhuthazwa. Lokhu kungenxa yokuthi, njengoba isikhumba siphola ngemva kokuhlinzwa, amaqhubu avame ukuphinda avele endaweni yokulimala. Lokhu kungenxa yokuthi umzimba uphatha indawo yokuhlinzwa "njengenxeba."

Yimiphi imithi enikezwa i-Pretibial Myxedema?

Udokotela wakho angakunika imithi efana nale ukusiza ekunciphiseni izimpawu zalesi simo:

• (Ama-Corticosteroids):Lena imithi yokwelapha esiza ekunciphiseni ukuvuvukala, ukuvuvukala, kanye nokulunywa.
• (Pentoxifylline): Lona umuthi ophuzwayo othuthukisa ukujikeleza kwegazi emilenzeni.
• (Octreotide): Lona umjovo. Unganciphisa ubukhulu bezigaxa ngaphansi kwesikhumba.
• (Rituximab): Lokhu futhi kuyindlela yokufakwa ngemithambo yegazi. Kusiza ama-antibodies omzimba wethu ukuthi asebenze kahle.
• I-Intravenous immunoglobulin (IVIG): Lona futhi umuthi ofakwa emthanjeni. Uthuthukisa ukusebenza kwama-antibodies ohlelweni lokuzivikela komzimba.

Ngaphambi kokuqala umuthi omusha, qiniseka ukuthi ukhuluma nodokotela wakho ngemiphumela yawo emibi, ukuthi kufanele uwuthathe isikhathi esingakanani, nokuthi ngabe uzodala izinkinga ngeminye imithi oyisebenzisayo njengamanje.

Ngizolulama ngokushesha kangakanani ngemva kokwelashwa?

Ubude besikhathi onayo izimpawu ze-Pretibial Myxedema buzohluka kuye ngokuthi isimo sakho sibucayi kangakanani. Ngokwelashwa, izimpawu zingase zithuthuke phakathi kwamasonto ambalwa kuya ezinyangeni ezimbalwa. Ngaphandle kokwelashwa, ngezinye izikhathi kungathatha iminyaka eminingana ukuthi isimo sizixazulule sodwa. Kodwa khumbula, uma ulimele emilenzeni yakho engezansi, isimo singaphinde sibuye.

Ingabe zikhona izindlela zokuvimbela lokhu (i-Pretibial Myxedema) ukuthi kungenzeki?

Ayikho indlela yokuvimbela lokhu ngokuphelele ukuthi kungenzeki, kodwa ungenza okulandelayo ukuze unciphise ingozi yakho:

• Ungasebenzisi imikhiqizo kagwayi.
• Uma unezimo ezithinta ukusebenza kwe-thyroid yakho, zitholele ukwelashwa ngendlela efanele.
• Gqoka amasokisi okucindezela noma amasokisi emilenzeni yakho.

Kuthiwani uma nami nginalesi simo? Ingabe kuyinto okufanele ngiyesabe?

Isibikezelo kubantu abane-Pretibial Myxedema ngokuvamile sihle. Uma izimpawu zakho zithinta ukubukeka kwakho kuphela, ungase ungadingi ukwelashwa. Uma unesifo esincane, ngokuvamile sizophela sodwa. Uma isimo sakho sibi kakhulu, isibikezelo sihle, kodwa kungathatha iminyaka eminingana ukululama ngokuphelele.

Ingabe ngidinga ukubona udokotela?

I-Pretibial Myxedema ingaphinde ivele ngisho noma isipholile, ikakhulukazi uma ulimele emlenzeni wakho ongezansi. Ngakho-ke, uma izimpawu zakho seziphelile bese ziphinde zibuye, khuluma nodokotela wakho. Futhi, uma unobuhlungu noma ukulunywa okukhulu, qiniseka ukuthi ubona udokotela.

Yimiphi imibuzo okufanele ngiyibuze udokotela?

Kungumqondo omuhle ukuba nemibuzo efana nalena uma uya kudokotela:

• Ngingawasebenzisa yini amasokisi okucindezela ukuze ngisize nge-Pretibial Myxedema?
• Ingabe ngidinga ukwelashwa kwe-Pretibial Myxedema?
• Ingabe izimpawu zami zibangelwa yisimo se-thyroid esingaphansi?
• Ngingasinakekela kanjani isikhumba sami esithintekile yi-Pretibial Myxedema?

Uyini umehluko phakathi kwe-(Pretibial Myxedema) kanye ne-(Erythema Nodosum)?

Zombili lezi zimo zithinta isikhumba sethu, ikakhulukazi isikhumba esisemilenzeni yethu ngaphansi kwamadolo. Kodwa-ke, kunezimpawu ezahlukene:

• (I-Pretibial Myxedema): Lokhu kubangela ukuvuvukala kanye nama-plaque acwebezelayo, ajiyile, afana nama-coral.
• (I-Erythema Nodosum): Lokhu kubangela ukuvuvukala kanye namaqhubu amancane, abuhlungu esikhumbeni.

Okokugcina, izinto okufanele uzikhumbule

I-Pretibial Myxedema yisimo esivame ukungadingi ukwelashwa. Ezimweni eziningi, siyaphela sodwa. Kodwa-ke, uma izinguquko ekubukekeni zikukhathaza, kunezindlela zokwelapha ezitholakalayo. Ukugqoka amasokisi okucindezela kungasiza ekunciphiseni ukuvuvukala futhi kukwenze uzizwe ukhululekile. Uma unobuhlungu noma ukulunywa okukhulu emilenzeni yakho engezansi, qiniseka ukuthi ukhuluma nodokotela. Futhi, lesi simo sivame ukuhlotshaniswa ne-Graves' Disease nezinkinga ze-thyroid, ngakho-ke kubalulekile ukuqaphela lokho futhi.

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