Ingabe ngezinye izikhathi uzizwa sengathi amehlo akho ayakhathala njengoba usuku luqhubeka, ulimi lwakho luyaxega uma ukhuluma, noma izitho zakho zomzimba ziyaphela amandla? Lokhu kungase kungabi ngenxa yokukhathala nje kuphela. Namuhla sikhuluma ngesimo esikhethekile esibizwa ngokuthi ' iMyasthenia Gravis ' esibangela izimpawu ezinjalo kanye nokwelashwa okusha okuye kwasetshenziswa kukho. Kubaluleke kakhulu ukuqaphela lokhu.
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Iyini ngempela iMyasthenia Gravis?
Kalula nje, i-myasthenia gravis yisimo esingapheli lapho uhlelo lokuzivikela lomzimba wethu, uhlelo lokuzivikela komzimba, luhlasela ngephutha amangqamuzana ethu anempilo. Lokhu kubizwa ngokuthi isifo sokuzivikela komzimba.
Cabanga nje, umlayezo othunyelwe usuka ebuchosheni bethu uhamba ngemizwa bese ufinyelela emisipheni, bese usebenza. Ukuhlangana kwemisipha phakathi kwemizwa nemisipha kuyalimala kulesi sifo. Amanye ama-antibodies akhiqizwa amasosha omzimba wethu afinyelela kule nhlanganisela futhi avimbele ukugeleza kwemiyalezo. Ngenxa yalokho , imisipha iqala ukuba buthaka kancane kancane .
Izinhlobo ezimbili eziyinhloko zama-antibodies ezibangela le nkinga yi -anti- acetylcholine receptor (AChR) kanye ne-anti-muscle-specific tyrosine kinase (MuSK) . Udokotela wakho uzokuchazela lokhu.
Yiziphi izimpawu ezivamile zalesi sifo?
Lezi zimpawu zingahluka kumuntu nomuntu. Futhi, lapho usebenzisa kakhulu imisipha, iba buthakathaka kakhulu. Ithebula elingezansi libala ezinye zezimpawu ezivame kakhulu.
| Isibonakaliso | Incazelo |
|---|---|
| Amajwabu amehlo athambile | Ukugoba okungalawuleki kweso elilodwa noma womabili. Abanye abantu bangase babone amabili. |
| Ushintsho ekubonakaleni kobuso | Ubuthakathaka bemisipha ebusweni nasemhlathini kungabangela izinguquko ezintweni ezifana nokumomotheka nokuveza intukuthelo. |
| Ubuthakathaka ezingalweni, emilenzeni, naseminweni | Ubunzima bokwenza imisebenzi yansuku zonke njengokuphakamisa okuthile, ukukama izinwele, noma ukuhamba. |
| Ubunzima bokugwinya | Ukuzizwa sengathi uyaminza lapho ugwinya ukudla noma isiphuzo. |
| Ubunzima bokukhuluma | Ukushintsha kwezwi lapho ukhuluma, kuzwakala sengathi ukhuluma ngekhala lakho, noma inkulumo eboshwe ulimi. |
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Check Availability →Isebenza kanjani isidakamizwa esisha i-Rystiggo?
I-Rystiggo (Rozanolixizumab-noli) umuthi omusha ovunyelwe ukwelapha i-myasthenia gravis. Ungowesigaba semithi ebizwa ngokuthi ama-neonatal Fc receptor (FcRn) blockers.
Manje ake sibone ukuthi lokhu kusebenza kanjani. Njengoba ngishilo ngaphambili, imbangela yalesi sifo ama-antibodies ayingozi (i-AChR kanye ne-MuSK) egazini lethu. Lokho uRystiggo akwenzayo ukuhlasela la ma-antibodies ayingozi nokusheshisa ukususwa kwawo emzimbeni wethu.
Kalula nje, lo muthi usebenza njengesihlungi esihlanza igazi lethu futhi sinciphise inani lama-antibodies amabi abangela lesi sifo.
Uma inani lala ma-antibodies lehla, ukuphazamiseka kokudluliselwa kwesignali phakathi kwemizwa nemisipha kuyancipha. Ngenxa yalokho, amandla emisipha ayanda futhi futhi izimpawu ziyalawulwa.
Ingabe lo muthi ulungele wonke umuntu?
Cha. I-Rystigmo ivunyelwe ukusetshenziswa kuphela ezigulini ezindala ezine-myasthenia gravis ezihlolwe ama-antibodies e-AChR noma e-MuSK egazini lazo. Abantu abangenawo la ma-antibodies bangase bangazuzi kulo muthi. Ngakho-ke, udokotela wakho uzonquma ukuthi lokhu kwelashwa kulungile yini kuwe.
Ukwelashwa kunikezwa kanjani futhi yimiphi imiphumela emibi?
Lo muthi uvame ukunikezwa njengomjovo ezicutshini ezingaphansi kwesikhumba esibhedlela noma emtholampilo. Lokhu kuvame ukunikezwa endaweni engaphansi kwenkinobho yesisu.
- Umjikelezo wokwelashwa:Lo mjovo uvame ukunikezwa kanye ngesonto amasonto ayisithupha. Lokhu kubizwa ngokuthi umjikelezo wokwelashwa. Ngemva kwalokho, ungahlala ngaphandle kokwelashwa isikhashana bese uqala umjikelezo omusha uma kudingeka. Konke lokhu kunqunywa udokotela wakho.
- Isexwayiso: Uzogcinwa ngaphansi kokuqashwa ngudokotela cishe imizuzu eyi-15 ngemuva komjovo, njengoba ngezinye izikhathi kungase kube nokusabela kokungezwani komzimba.
| Ingozi/umphumela ongemuhle | Okufanele ukwenze nokuthi yini okufanele ukwazi |
|---|---|
| Izimo lapho kufanele wazise udokotela wakho ngokushesha | |
| Izifo Ezisebenzayo | Uma unezimpawu ezifana nomkhuhlane, izinhlungu zomzimba, ukukhwehlela, i-phlegm, ubunzima bokuphefumula, noma isifo sohudo, tshela udokotela wakho ngokushesha ngaphambi noma ngesikhathi sokwelashwa. Ukwelashwa kungadingeka kuhlehliswe kuze kube yilapho ukutheleleka kuphelile. |
| Imiphumela emibi evamile | |
| Ikhanda elibuhlungu | Lokhu ngokuvamile kuyinto encane. Uma kukhulu noma kuqhubeka, tshela udokotela wakho. |
| Isicanucanu kanye nesifo sohudo | Lokhu kuvamile emasontweni ambalwa okuqala okwelashwa. Phuza amanzi amaningi bese udla ukudla okungemnandi (irayisi, ubhanana). Uma kuqhubeka, tshela udokotela wakho. |
| Ukusabela kwendawo yomjovo | Kungase kube nokubomvu, ukulunywa, kanye nokuvuvukala endaweni yokujova. Lokhu kungancishiswa ngokushintsha indawo yokujova kunokuba ujove endaweni efanayo isikhathi ngasinye. |
Ingabe kungaba nezinkinga ngeminye imithi kanye nemijovo?
Yebo, leyo yindaba ebaluleke kakhulu.
- Imithi Yokugoma: Eminye imithi yokugoma ayikwazi ukunikezwa ngaphambi noma ngesikhathi sokwelashwa nge-Rystiggo. Ngakho-ke, tshela udokotela wakho kusengaphambili nganoma yimiphi imithi yokugoma oyitholayo.
- Eminye imithi: Eminye imithi oyithathayo, ikakhulukazi ukwelashwa okuhlobene nokuzivikela komzimba njenge- Intravenous Immunoglobulin (IVIg) , kanye nama-antibody e-monoclonal , kungase kuhlangane ne-Rystiggo.
Ngakho-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini nemikhiqizo yamakhambi) ngaphandle kokufihla lutho.
Wazi kanjani ukuthi umuthi uyasebenza?
Emasontweni ambalwa okuqala i-Rystiggo, uzoqala ukuzwa imisipha yakho iqina futhi izimpawu zakho ziba ngcono. Kodwa-ke, noma izimpawu zakho ziba ngcono, ungalokothi uyeke ukuthatha umuthi ngaphandle kweseluleko sikadokotela wakho. Ukwenza kanjalo kungenza izimpawu zakho zibuye. Khuluma nodokotela wakho njalo ngesimo sakho.
Umlayezo Wokuya Nawe Ekhaya
- I-Myasthenia Gravis yisifo lapho amasosha omzimba ethu ehlasela khona imisipha yethu.
- I-Rystigmo iyindlela entsha yokwelapha lesi sifo. Isiza ukususa ama-antibodies ayingozi abangela lesi sifo emzimbeni.
- Lokhu kwelashwa akufanele wonke umuntu. Udokotela wakho uzonquma ukuthi lokhu kulungile yini kuwe ngokuhlola ukuthi unama-antibodies e-AChR noma e-MuSK egazini lakho.
- Uma uba nezimpawu zokutheleleka njengomkhuhlane nokukhwehlela ngesikhathi sokwelashwa, yazisa udokotela wakho ngokushesha.
- Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke eminye imithi oyithathayo.
- Gwema ukuyeka imithi enikezwe udokotela ngaphandle kweseluleko sezokwelapha nganoma yisiphi isizathu.
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