Umbuzo omnye ofika engqondweni ubuncinane kube kanye kumntu ofumana unyango lomhlaza webele ngulo, 'Ngaba esi sifo siphelile ngokupheleleyo ngoku?' Loo loyiko lusengqiqweni kakhulu. Kodwa iindaba ezimnandi zezokuba uninzi lwexesha, umhlaza webele awubuyi. Nangona kunjalo, ngamanye amaxesha unokubuya.
Ukuba ibuya, siyibiza ngokuba ' kukuphinda ivele kwakhona' . Zininzi iindlela oku okunokwenzeka ngazo. Enye kukuba ibuya kwibele elifanayo nomhlaza wokuqala okanye kwindawo ekufutshane. Ngamanye amaxesha inokusasazeka kwii-lymph nodes ezikufutshane. Ngamanye amaxesha, inokusasazeka kwiindawo ezikude zomzimba, njengamathambo okanye imiphunga.
Ugqirha ugxile kwintoni?
Ukususela kwixesha lokuqala ufunyaniswa ukuba unomhlaza webele, oogqirha bakho baya kujonga izinto eziya kwandisa umngcipheko wokuba ubuye. Olu lwazi luya kubanceda bagqibe ukuba loluphi unyango olulungele wena.
"Asinakutsho ngokuqinisekileyo ngokupheleleyo ukuba umhlaza uza kubuya. Kodwa ngoku singakuxela kwangaphambili ngamathuba aphezulu kakhulu kunangaphambili," itsho ingcali.
Kubekho inkqubela phambili enkulu kweli candelo kwiminyaka eli-10 idlulileyo, ingakumbi kwimidla yomhlaza ene- estrogen -receptor.
Ngamafutshane, okukhona ithumba likhulu, kokukhona lisasazeka kwezinye izicwili, kokukhona umngcipheko wokuphinda libuye. Kwakhona, i-biology yomhlaza ibaluleke kakhulu. Oko kukuthi, zeziphi ii-receptors ezithile ezikhoyo kwiiseli zomhlaza. Umzekelo, uhlobo lomhlaza webele olubizwa ngokuba yi-"triple-negative" (oko kukuthi, umhlaza ongenazo zonke ii-receptors ezintathu ze-estrogen, i-progesterone, kunye ne-HER2) lunokuphinda lubuye.
| Izinto ekufuneka ziqwalaselwe xa kuvavanywa umngcipheko | Kutheni oko kubalulekile? |
|---|---|
| Ubudala bakho kunye nokuba sele udlule kwixesha lokuya exesheni okanye cha | Ubudala kunye namanqanaba eehomoni anokuchaphazela umngcipheko. |
| Ubungakanani bethumba | Iithumba ezinkulu ngokubanzi zinxulunyaniswa nomngcipheko ophezulu wokuphinda zivele. |
| Nokuba sele isasazeke na ukuya kuma-lymph nodes | Ukubakho kweeseli zomhlaza esitulweni kubonisa ukuba umhlaza ungasasazeka. |
| Imeko yomhlaza we-receptor | Unyango kunye nomngcipheko ziyahluka ngokuxhomekeke ekubeni umhlaza une-ER-positive, i-PR-positive, i-HER2-positive, okanye i-triple-negative. |
Uvavanyo olukhethekileyo olujonga nzulu umngcipheko
Ngamanye amaxesha, ukuba umhlaza mkhulu kakhulu okanye usasazeke kwiindawo ze-lymph nodes, kunzima ukutsho ngqo ukuba yintoni ingozi. Oogqirha bakubiza oku ngokuthi 'yi-grey zone.'
Kwiimeko ezinje, kukho iimvavanyo ezikhethekileyo ezinokubonelela ngolwazi oluthe kratya. Nangona kunjalo, ayizizo zonke ezi vavanyo ezifanelekileyo kuzo zonke iintlobo zomhlaza.
- I-Oncotype DX: Olu lolona vavanyo lusetyenziswa kakhulu. Lujonga ii-genes ezingama-21 kwisampulu encinci yomhlaza wakho. Ngokuxhomekeke ekubeni ezo genes zisebenza kakuhle kangakanani, ufumana 'amanqaku okubuyela umva' phakathi kwe-0 ne-100. Olu vavanyo lunokunceda ugqirha wakho aqonde ukuba umhlaza wakho ubuyela umva kangakanani kwixesha elizayo kunye nokuba uza kuzuza na kwi-chemotherapy. Nangona kunjalo, olu vavanyo lunokwenziwa kuphela kwii-cancers ezine-estrogen-receptor positive kwaye ezingasasazekanga kwi-lymph nodes.
- Ezinye iimvavanyo: Kukwakho neemvavanyo ezibizwa ngokuba yi-`(MammaPrint)`, `(Breast Cancer Index)`, `(Pam50)`, kunye ne-`(EndoPredict)`. Ezinye zezi zinceda ekuqikeleleni umngcipheko wokubuya komhlaza emva kweminyaka emihlanu.
Uvavanyo lwegazi lwexesha elizayo
Iqela labaphandi okwangoku lizama ukwenza uvavanyo lwegazi olunokufumanisa ukuba umhlaza uphinda ubuye na.
Olu hlobo lovavanyo lubaluleke kakhulu emva kokuba zonke iindlela zonyango zigqityiwe, xa kungekho zicubu zomhlaza ezisele zijongwa.
“Ukuba sinokwazi ngokuchanekileyo ukuba ngubani oza kuphinda abe nomhlaza kwakhona, singagqiba kwelokuba bayalufuna na unyango olongezelelweyo. Emva koko singaqala ukuphanda unyango olutsha olubasebenzela ngokukhawuleza,” utshilo omnye woososayensi ababandakanyekayo kolu phando. “Injongo yethu ephambili kukuthintela umhlaza webele osasazekayo, okunzima ukuwulawula kwaye ubangela ama-90% okufa komhlaza webele.”
Nangona kunjalo, kuthiwa kuza kuthatha iminyaka eliqela ukwenza uvavanyo lwegazi olunokusetyenziswa ngoogqirha .
Ungenzani?
Zikho izinto onokuzenza de izazinzulu zifumane iimvavanyo ezintsha ezifana nezi. Imikhwa yakho yemihla ngemihla inokunceda ekunciphiseni lo mngcipheko. Umzekelo, kubalulekile ukuzilolonga rhoqo nokugcina ubunzima obusempilweni .
Enye into ekufuneka uyikhumbule kukuba umngcipheko wokuphinda ubuye kunye namazinga okusinda zizinto ezimbini ezahlukeneyo . Oku kubaluleke kakhulu. Khawucinge ngomntu onomhlaza webele, afumane unyango, aze umhlaza ubuye emva kweminyaka emibini. Kodwa ukuba ufunyenwe kwangethuba, loo mntu angaphila ubomi obulungileyo amashumi eminyaka.
Ngoko ke, ungaphoswa ziintlanganiso zakho zokulandelela. Ukuba unemibuzo okanye iinkxalabo, qiniseka ukuba ubuza ugqirha wakho.
"Kubalulekile ukuthetha nogqirha wakho uze uqonde kakuhle ukuba yintoni ingozi yakho kunye nokuba ithetha ukuthini. Oku kuya kukunceda wenze izigqibo ezifanelekileyo malunga nonyango lwakho. Ukujongana nomhlaza kunokuba ngamava othusayo nadidayo. Ngoko ke kufuneka uzive ukhululekile ukuthetha nogqirha wakho malunga noloyiko lwakho."
Umyalezo Wokuya Ekhaya
- Ixesha elininzi, umhlaza webele awuphindi ubuye emva konyango, ngoko ke ungoyiki ngokungeyomfuneko.
- Umngcipheko wokubuya komhlaza uxhomekeke kwizinto ezifana nobukhulu bethumba, ukusasazeka kwezicubu ezikufutshane, kunye nohlobo lomhlaza webhayoloji.
- Ukuze bazi umngcipheko wakho ochanekileyo kwaye bakhethe unyango olungcono, oogqirha banokusebenzisa iimvavanyo ezikhethekileyo ezifana ne-Oncotype DX.
- Unokunceda ekunciphiseni lo mngcipheko ngokwenza umthambo rhoqo nokugcina ubunzima bomzimba busempilweni.
- Eyona nto ibalulekileyo kukuthetha ngokukhululekileyo nogqirha wakho. Mamela zonke izinto ozixhalabileyo kunye nemibuzo yakho. Kwakhona kubaluleke kakhulu kwimpilo yakho yengqondo.
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