Ingabe imithambo yakho yegazi ingonakalisa nemithambo yegazi? Ake sixoxe nge-Fibrinoid Necrosis!

Imithambo yegazi emincane esakazeke emzimbeni wethu ifana namapayipi athwala amanzi. Lena yileyo ethwala igazi iye kuzo zonke izingxenye zomzimba wethu. Ngakho-ke, kwenzekani uma okuthile kulimaze le mithambo yegazi? Namuhla sizokhuluma ngesimo esingaba sibi kakhulu, futhi leso yisimo esibizwa ngokuthi i-Fibrinoid Necrosis . Ungesabi, ake sikuqonde kalula lokhu.

Kuyini i-fibrinoid necrosis?

Kalula nje, i-fibrinoid necrosis iwukulimala kwezindonga zangaphakathi zemithambo yegazi emincane emizimbeni yethu, ikakhulukazi imithambo yegazi emincane . Cabanga ngakho njengokuqhuma kwepayipi lamanzi. Lapho imithambo yegazi yonakele ngale ndlela, ingaqhekeka, ilimale , yophe igazi, futhi ivuvuke ngisho nangaphakathi emzimbeni.

Igama elithi “necrosis” lisho ukufa kwamangqamuzana . Lisho ukufa kwamangqamuzana ngenxa yengozi, ukulimala, noma ukulahlekelwa igazi. I-Fibrinoid necrosis iyinto efanayo, okusho ukuthi amangqamuzana asezindongeni zemithambo yegazi ayafa.

Lesi simo sivela kanjani?

Lokhu kungase kubonakale kuyinkimbinkimbi kancane, kodwa cabanga ngakho ngale ndlela. Sinesimiso sokuzivikela emizimbeni yethu. Kufana namandla okuzivikela emizimbeni yethu. Yilesi simiso esisivikela ezifweni . Kodwa ngezinye izikhathi lesi simiso sokuzivikela siba namandla ngokweqile noma sidideke.

Ku-fibrinoid necrosis, amasosha omzimba asebenza ngokweqile futhi akhiphe izinto ezithile. Lezi zinto zinamathela ezindongeni zangaphakathi zemithambo yegazi yethu. Bese kuba nokuvuvukala , okusho ukuvuvukala nokubomvu. Lokhu kuvuvukala kubangela ukuthi amangqamuzana asezindongeni zemithambo yegazi afe. ​​Ngamanye amazwi, kunjengokungathi izivikelo zethu zihlasela amangqamuzana ethu.

Yini ebangela i-fibrinoid necrosis?

Noma yisiphi isimo esingalimaza imithambo yegazi singabangela lokhu. Kunezici eziningana eziyinhloko ezibangela lokhu:

• Umfutho wegazi ophakeme kakhulu: Lokhu kubizwa ngokuthi (i-Malignant Hypertension) noma (i-Hypertensive Crisis) . Ngokuvamile, umfutho wegazi womuntu ophilile kufanele ube ngaphansi kuka-130/80 mmHg. Kodwa-ke, kulesi simo esibizwa ngokuthi (i-Malignant Hypertension), umfutho wegazi ukhuphukela ku-180/120 mmHg noma ngaphezulu. Uma lokhu kwenzeka,I-Fibrinoid necrosis ingenzeka ngokulimaza imithambo yegazi ethwala igazi iye ezithweni ezibalulekile njengenhliziyo , ubuchopho nezinso. Lesi yisimo esiphuthumayo esibucayi kakhulu futhi sidinga usizo lwezokwelapha ngokushesha.

• Izifo ezihlasela umzimba : Njengoba kushiwo ngaphambili, lezi yizifo lapho amasosha omzimba ethu ehlasela khona imizimba yethu. Isibonelo:
• (Isifo Samathambo Esibangelwa Yi-Rheumatoid )
• (Lupus) (Isifo se-Lupus – sithinta izitho eziningi ezifana nesikhumba, amalunga, nezinso)
• (I-Rheumatic Fever – isimo esingase senzeke ngemva kokutheleleka komphimbo futhi sithinte inhliziyo)

• I-Preeclampsia: Lesi yisimo abanye omama abasithola ngesikhathi sokukhulelwa. Sibonakala ngomfutho wegazi ophakeme kanye nezinye izimpawu.

• (I-Subacute Bacterial Endocarditis): Lokhu ukutheleleka kwebhaktheriya kwengaphakathi lenhliziyo.

• I-Vasculitis: Kalula nje, ukuvuvukala kwemithambo yegazi, okusho ukuvuvukala. Izibonelo zalokhu zifaka:
• (I-Polyarteritis Nodosa)
• (IgA Vasculitis) (eyayaziwa ngokuthi iHenoch-Schönlein purpura)

Manje cishe uyaqonda ukuthi lesi simo asibangelwa yisizathu esisodwa nje kuphela, kodwa singahlotshaniswa nezifo ezahlukahlukene.

Ziyini izimpawu zalesi simo?

Ngenxa yokuthi i-fibrinoid necrosis ilimaza imithambo yegazi, uphawu oluyinhloko ukopha . Lokhu kungenzeka ngezindlela ezahlukene:

• Izinsini eziphuma igazi.
• Igazi esitulweni (esimnyama noma esibomvu ngokumnyama).
• Igazi emchameni – lokhu sikubiza ngokuthi (i-Hematuria) .
• Ukuphuka ezindaweni ezahlukene emzimbeni (njengokungathi kuphukile ngaphandle kokushaywa ndawo).
• Ukopha ngaphakathi emzimbeni (lokhu akubonakali ngaphandle, kodwa kungaqondwa kwezinye izimpawu).
• Ukopha ekhaleni.

Uma unesifo sokopha kanje, ungakushayi indiva . Kubaluleke kakhulu ukufuna iseluleko sezokwelapha.

Yiziphi izinkinga ezingaba khona ze-Fibrinoid Necrosis?

Izinkinga ezivela kulesi simo zivame ukuxhomeka esifweni esisibangele. Ngokwesibonelo:

• Le esikhulume ngayo (i-Malignant Hypertension) , okungukuthi, uma kwenzeka i-fibrinoid necrosis emithanjeni yegazi yezinso ngenxa yomfutho wegazi ophakeme, ingaholela ekuhlulekeni kwezinso .
• Uma lesi simo sibangelwa yisifo esifana ne -lupus , izilonda zesikhumba nesifo senhliziyo zingavela.

Lokho kusho ukuthi izinkinga azinqunywa nje kuphela yi-fibrinoid necrosis, kodwa futhi nayisifo esiyisisekelo.

Lesi sifo sitholakala kanjani? (Ukuxilongwa)

Uma amangqamuzana efa, akhipha into ebizwa ngokuthi i-fibrin . Le nto ebizwa ngokuthi i-fibrin iwubufakazi obuyinhloko bokuhlonza lesi sifo.

Odokotela bezifo , abangochwepheshe ekuxilongeni izifo, bathatha isampula yezicubu ezonakele bese bezibheka ngaphansi kwesibonakhulu. Bese bebona ukuthi le nto (i-Fibrin) ifakiwe yini.

Ukuthatha isampula yezicubu kubizwa ngokuthi i-biopsy . Indlela lokhu kuhlolwa okwenziwa ngayo iyahlukahluka kuye ngokuthi isifo sikuphi:

• Ukuhlolwa kwesikhumba: Ungqimba oluncane lwesikhumba lungasuswa ebusweni besikhumba, noma kuthathwe ucezu oluncane ngethuluzi elikhethekile (ithuluzi lokubhoboza). Ngezinye izikhathi kungenziwa ukusika okuncane ukuze kuthathwe isampula kusuka ekujuleni.
• Ukuhlolwa kwangaphakathi kwezicubu: Ukuze kuthathwe isampula yezicubu esithweni esingaphakathi komzimba, odokotela basebenzisa inaliti noma ithuluzi elibizwa ngokuthi i-endoscope . I-endoscope iyipayipi elincane elinekhamera kanye nezinsimbi ezincane ngakolunye uhlangothi. Lokhu kungadluliselwa ngaphakathi komzimba ukuze kuthathwe isampula yezicubu.

Iphathwa kanjani? (Ukwelashwa)

Uma ngikhuluma iqiniso, akukho ukwelashwa okuqondile nokujwayelekile kwe-fibrinoid necrosis. Kodwa-ke, odokotela bangakwazi ukulawula ukopha . Kuya ngendawo kanye nohlobo lokopha.

Ngaphezu kwalokho, into ebaluleke kakhulu ukwelapha isifo esiyisisekelo esibangele i-fibrinoid necrosis .

Isibonelo, uma umfutho wegazi ophezulu uyimbangela, kunikezwa imithi yokuwulawula. Uma kuyinkinga ngesimiso somzimba sokuzivikela, kunemithi yokuwulawula nokuvimbela umonakalo owengeziwe emithanjeni yegazi.

Ngakho-ke, ukugxila okuyinhloko kokwelashwa ukwelapha imbangela eyisisekelo .

Ungazivikela kanjani ku-fibrinoid necrosis? (Ukuvimbela)

Esikhundleni sokuzama ukuzivikela ngokuphelele kulokhu, into engcono kakhulu ongayenza ukunciphisa ingozi yokuthola izimo ezibangela lokhu.

• Bona udokotela wakho njalo ukuze akuhlole. Ngaleyo ndlela, uma kunenkinga yempilo, ingatholakala futhi yelashwe ngaphambi kokuba ibe yingozi kakhulu.
• Uma usuvele unesifo esingadala lokhu (isib. umfutho wegazi ophakeme, isifo sikashukela, isifo sokuzivikela komzimba), landela imiyalelo kadokotela wakho ngqo . Thatha imithi yakho ngesikhathi futhi ulondoloze indlela yakho yokuphila njengoba uyalelwe.

Liyini ikusasa lomuntu onalesi simo? (Isibikezelo)

Lokhu kuncike kakhulu ebunzimeni besimo esiyisisekelo esibangele i-fibrinoid necrosis. Ezinye izimo zingaba khona impilo yonke, zinciphise ikhwalithi yokuphila, futhi zingase ziholele nasekufeni ngaphambi kwesikhathi.

Isibonelo, uma lesi simo esishiwo ngenhla (i-Malignant Hypertension) singelashwa ngokushesha, isikhathi sokuphila kwesiguli singancishiswa ngeminyaka emibili. Yingakho kubalulekile ukufuna iseluleko sezokwelapha ngokushesha nje lapho kuvela izimpawu.

Kufanele ubonane nini nodokotela?

Uma kwenzeka uthola ukuthi unemithambo yegazi eyonakele, noma uma unezinye zezimpawu okukhulunywe ngazo ngaphambili (ikakhulukazi ukopha okungachazeki), kubalulekile ukubona udokotela ukuze uthole ukulandelwa okufanele.

Ngokulandela uhlelo lokwelashwa udokotela wakho akunikeza lona ngqo, ungalawula isimo sakho futhi uvimbele umonakalo owengeziwe.

I-Fibrinoid necrosis yisimo esonakalisa imithambo yegazi. Izimo ezibangela lokhu zingaba zimbi kakhulu, ngakho-ke ukuqapha udokotela kuyadingeka. Ngokubona udokotela wakho njalo, ungaphatha impilo yakho kangcono futhi uvimbele izinkinga ezivela ezimweni ezingaphansi.

Umlayezo Wokuya Nawe Ekhaya

• I-Fibrinoid necrosis iwukulimala kwemithambo yegazi emincane.
• Izimbangela eziyinhloko zalokhu yizimo ezifana nomfutho wegazi ophakeme kanye nezifo ezihlasela amasosha omzimba.
• Uphawu oluyinhloko yizinhlobo ezahlukene zokopha.
• Kungadingeka i-biopsy ukuze kutholakale isifo.
• Ukwelashwa kuqondiswe kakhulu embangela eyinhloko.
• Kubaluleke kakhulu ukufuna iseluleko sezokwelapha uma unezimpawu noma izici eziyingozi, njengoba kungaba yinto enkulu uma inganakwa.

Ngiyethemba ukuthi lolu lwazi luwusizo kuwe. Hlala uphilile!