Ake sifunde ngomuthi i-Fluorouracil (5-FU), ozokusiza ekulweni nomdlavuza!

Kuvamile ukuzwa umthwalo osindayo uma uzwa ukuthi wena noma umuntu oseduze nawe unomdlavuza. Ngesikhathi esifanayo, lapho odokotela bekhuluma ngokwelashwa kwalokhu, ikakhulukazi uma bezwa amagama anjengokuthi "i-chemotherapy", kungaba yinto esabekayo kancane. Kodwa uma unolwazi olufanele ngalezi zinto, uzothola amandla amaningi okuqhubeka nalolu hambo. Namuhla sizokhuluma ngomuthi osetshenziswa kakhulu osiza ukulwa namaseli omdlavuza. Lowo yi -Fluorouracil , abanye bawubiza nangokuthi yi -5-FU .

Uhlobo luni lomuthi i- Fluorouracil (5-FU)?

Kalula nje, i-fluorouracil umuthi olawula ukukhula kwamaseli omdlavuza, okungukuthi, uyawanciphisa . Njengokulawula ukhula, kusiza ukuvimba amaseli omdlavuza ukuthi angasabalali. Luhlobo lwe-chemotherapy. Odokotela basebenzisa lo muthi ukwelapha izinhlobo eziningi ezahlukene zomdlavuza. Nazi izibonelo ezimbalwa:

• Umdlavuza webele
• Umdlavuza wekholoni noma we-rectal
• Umdlavuza we-pancreatic
• Umdlavuza wesisu

Lomuthi ngezinye izikhathi ungatholakala ngaphansi kwamanye amagama, isibonelo `i-Adrucil`. Futhi, udokotela wakho angawusebenzisa lo muthi ngezinye izinjongo kuye ngesimo sakho. Ngakho-ke uma unemibuzo, kungcono ukubuza udokotela wakho noma usokhemisi.

Yiziphi izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala lo muthi?

Leli iphuzu elibaluleke kakhulu. Ngaphambi kokuthi uqale ukuthatha lo muthi, kubalulekile ukunikeza udokotela wakho incazelo ephelele yesimo sakho sempilo. Ngisho nento encane kakhulu kufanele itshelwe ngaphandle kokuyifihla. Ngoba, ngokusekelwe kulolo lwazi, kunqunywa izinto ezinjengokuthi lo muthi ukufanele yini nokuthi kufanele unikeze malini. Uma unanoma yikuphi kwalokhu okulandelayo, qiniseka ukuthi utshela udokotela wakho:

• Uma kukhona isifo noma inkinga egazini (Izinkinga zegazi).
• Ukuntuleka kwe-Dihydropyrimidine Dehydrogenase (DPD) kuyisimo esibangelwa izakhi zofuzo. Abantu abaswele le enzyme bangase babe nobunzima bokubekezelela umuthi i -fluorouracil , okungadala imiphumela emibi kakhulu. Yingakho kubalulekile ukukhuluma ngakho.
• Noma yikuphi ukutheleleka kwamanje , ikakhulukazi ukutheleleka ngegciwane njenge- chickenpox kanye ne-herpes`(Ukutheleleka ngegciwane njenge-chickenpox, izilonda zomkhuhlane , noma i-herpes)`.
• Isifo sezinso .
• Isifo sesibindi.
• Uma ungondlekile kahle , okungukuthi, uma ungatholi ukudla okwanele neziphuzo, futhi isimo sakho sokudla siphansi.
• Uma usanda kuthola ukwelashwa ngemisebe noma okwamanje uyakuthola .
• Uma une-allergy engavamile noma ebangelwa yi -fluorouracil , eminye imithi ye-chemotherapy, noma yimuphi omunye umuthi, ukudla, udayi, noma izithasiselo .
• Uma ukhulelwe noma uzama ukukhulelwa , lokhu kubaluleke kakhulu.
• Uma ungumama oncelisayo .

Hhayi lezi zinto kuphela, kodwa futhi tshela udokotela wakho nganoma yiziphi izinkinga zempilo onazo.

Ngingakunika kanjani lo muthi?

I-Fluorouracil (5-FU) ivame ukunikezwa njengomjovo emthanjeni noma njengokufakwa emthanjeni, okufana ne-saline . Lokhu akuyona into ongayenza ekhaya. Lokhu kwelashwa kunikezwa esibhedlela noma emtholampilo nguchwepheshe wezempilo oqeqeshwe ngokukhethekile ukwenza lokhu. Kumelwe kuthathwe ukunakekelwa okukhethekile lapho kunikezwa lo muthi ezinganeni ezincane. Uma ingane yakho izonikezwa lo muthi, khuluma nodokotela wezingane ngakho.

Kuthiwani uma ngiphuza umuthi omningi kakhulu? Noma uma ngiphuthelwa umthamo?

Uma ucabanga ukuthi usuthathe lo muthi omningi kakhulu, shayela isikhungo sokulawula ubuthi noma igumbi lezimo eziphuthumayo ngokushesha . Kubaluleke kakhulu ukuthatha umuthi wakho njengoba nje udokotela wakho ekuyalele. Uma nganoma yisiphi isizathu ungakwazi ukuza ukuzokwelashwa ngosuku oluhleliwe, shayela udokotela wakho noma umhlinzeki wezempilo ngokushesha bese ubazisa .

Yikuphi okunye ukusebenzisana okungenzeka nalomuthi?

Kunemithi ethile engabangela izinkinga uma ithathwa nge- fluorouracil . Ngakho-ke, kufanele utshele udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa amavithamini, imithi yamakhambi, kanye nezithasiselo zokudla. Ikakhulukazi, akufanele uthathe i-fluorouracil kanye nemithi elandelayo :

• Imithi yokugomela igciwane eliphilayo : Ngenxa yokuthi amasosha omzimba wakho angase abe buthaka uma uthatha lo muthi, ukuthola imithi yokugomela equkethe amagciwane aphilayo kungabangela ukutheleleka.

Futhi, kuneminye imithi engasebenzisana ne -fluorouracil . Isibonelo:

• Imithi evimbela noma elapha ukujiya kwegazi (isib. i-warfarin, i-enoxaparin, i-dalteparin).

Lolu hlu aluphelele. Ngakho-ke, tshela udokotela wakho ngayo yonke imithi oyiphuzayo, ugwayi owubhemayo, utshwala obuphuzayo, kanye nezidakamizwa ezingekho emthethweni ozisebenzisayo . Ezinye izinto zingathintana nemithi yakho.

Yiziphi izinto okufanele uziqaphele lapho uthatha imithi?

Udinga ukunakekela umzimba wakho kahle ngenkathi uthatha ukwelashwa nge-fluorouracil .

• Bona udokotela wakho njalo bese uhlola isimo sakho .
• Lo muthi ungakwenza uzizwe ungakhululekile futhi ubuhlungu kakhulu kunokujwayelekile . Lokhu kuvamile. Lokhu kungenxa yokuthi imithi ye-chemotherapy ingathinta hhayi kuphela amangqamuzana omdlavuza, kodwa namaseli anempilo. Kodwa-ke, qhubeka nokwelashwa okunikezwe udokotela wakho kuze kube yilapho ekutshela ukuthi uyeke .
• Uma uhlangabezana nanoma yimiphi imiphumela emibi, tshela udokotela wakho . Ngezinye izikhathi eminye imithi inganikezwa ukulawula imiphumela emibi. Landela imiyalelo yokusebenzisa umuthi njengoba nje kuyalelwe.
• Uma unomkhuhlane, ukubanda, umphimbo obuhlungu, noma ezinye izimpawu zomkhuhlane , tshela udokotela wakho noma umhlinzeki wezempilo ngokushesha . Ungaphuzi noma yimuphi umuthi ozizwa sengathi uwuthatha. Lo muthi unganciphisa ikhono lomzimba wakho lokulwa nokugula. Ngakho-ke, zama ukuhlala kude nabantu abagulayo ngangokunokwenzeka.
• Lo muthi ungandisa ingozi yakho yokopha noma ukuklwebheka . Tshela udokotela wakho uma ubona noma yikuphi ukopha okungajwayelekile (isib. ukopha ekhaleni, ukopha kwezinsini, igazi esitulweni sakho).
• Qaphela kakhulu lapho uxubha, ufaka i-floss, futhi usebenzisa i-toothpick . Lokhu kungabangela kalula ukuthi izinsini zakho zilimale, zithole izifo, noma zophe igazi. Uma uzokwelashwa ngamazinyo, tshela udokotela wamazinyo ukuthi uthatha lo muthi.
• Ungaphuzi imithi yokubulala izinhlungu efana ne -aspirin, i-paracetamol, i-ibuprofen, i-naproxen, ne-ketoprofen ngaphandle kweseluleko sikadokotela wakho. Le mithi ingacindezela izimpawu ezifana nomkhuhlane.
• Ungakhulelwa ngenkathi uthatha lo muthi . Uma owesifazane okhulelwe ethola lo muthi, ungabangela umonakalo omkhulu enganeni engakazalwa. Uma uzama ukukhulelwa noma ucabanga ukuthi ukhulelwe, tshela udokotela wakho ngokushesha. Buza udokotela wakho noma usokhemisi ukuthola ulwazi olwengeziwe. Ungancelisi ibele ngenkathi uthatha lo muthi .
• Amadoda nawo kufanele aqaphele lokhu . Uma uzama ukuba nomntwana, tshela udokotela wakho ngakho, njengoba lo muthi unganciphisa inani lesidoda.
• Unesifo sohudo (ubuhlungu besisu).Uma unesifo sohudo, ungasithathi ekhemisi wedwa. Uma isifo sohudo sithatha izinsuku ezingaphezu kwezimbili, sibi kakhulu, noma sinamanzi, tshela udokotela wakho.
• Lo muthi ungenza isikhumba sakho sizwele kakhulu elangeni . Ngakho-ke, nciphisa ukuchayeka kwakho elangeni ngangokunokwenzeka. Uma uphuma ngaphandle, gqoka izingubo ezimboza umzimba wakho kahle, gqoka izibuko zelanga, bese usebenzisa i-sunscreen. Ungasebenzisi izibani zelanga noma imibhede/amadokodo okushiswa kwesikhumba.

Yimiphi imiphumela emibi okufanele ngiyitshele udokotela ngokushesha?

Njengayo yonke imithi, i-fluorouracil ingabangela imiphumela emibi. Eminye ayibi mibi kangako, kodwa kufanele utshele udokotela wakho uma uhlangabezana nanoma yimiphi yale miphumela emibi . Lokhu kufaka phakathi:

• Ukusabela kokungezwani komzimba : ukuqubuka kwesikhumba, ukulunywa, amaqhubu, ukuvuvukala kobuso, izindebe, noma ulimi.
• Ukwehla kwenani legazi : Lo muthi ungabangela ukwehla kwenani lamaseli amhlophe egazi (amaseli alwa nezifo), amaseli abomvu egazi (amaseli athwala umoya-mpilo), kanye nama-platelet (amaseli asiza ukujiya kwegazi). Lokhu kungandisa ingozi yakho yokutheleleka nokopha .
• Izimpawu zokutheleleka : umkhuhlane noma ukubanda, ukukhwehlela, umphimbo obuhlungu, ubuhlungu noma ubunzima bokuchama.
• Izimpawu zama-platelet aphansi noma ukopha : ukuklwebheka ezindaweni emzimbeni, amachashazi amancane abomvu esikhumbeni (njengokuhlatshwa yiphini), umnyama, indle ephuzile, igazi emchameni.
• Izimpawu zamaseli abomvu aphansi : ukuzizwa ukhathele ngendlela engavamile, ukuzizwa ubuthakathaka lapho umi, ukuzizwa unesizungu.
• Ubunzima bokuphefumula .
• Ukushintsha kombono (isib. ukubona okufiphele).
• Ubuhlungu besifuba .
• Izilonda zomlomo (ngaphakathi emlonyeni, ezindebeni).
• Ukucanuzela nokuhlanza (okuvamile noma okunzima).
• Ubuhlungu, ukuvuvukala, kanye nokubomvu endaweni yomjovo .
• Ubuhlungu, ukuba ndikindiki, noma umuzwa wokuqina ezandleni noma ezinyaweni .
• Ukubomvu, ukuvuvukala, noma ubuhlungu bezintende noma amathe (okubizwa nangokuthi 'i-Hand-Foot Syndrome').
• Ubuhlungu besisu (obukhulu).
• Ukopha okungavamile .

Uma uhlangabezana nanoma yiziphi zalezi zimpawu, ungachithi isikhathi futhi wazise udokotela wakho noma isibhedlela lapho welashwa khona ngokushesha .

Yimiphi imiphumela emibi evame ukuba yingozi ngokwanele ukutshela udokotela , kodwa okufanele ibikwe uma iqhubeka noma ikhathaza?

Kuneminye imiphumela emibi, ayibi mibi kangako, kodwa uma iqhubeka noma uma ikukhathaza, kungcono ukutshela udokotela wakho.

• Izinguquko ezinzipho zomunwe noma zezinzwane (isib., ukushintsha kombala, ukuphuka kalula).
• Uhudo (olungabi lubi kakhulu, luyaphela ezinsukwini ezimbalwa).
• Isikhumba esomile noma esilumayo .
• Ukulahlekelwa izinwele . Lokhu kwenzeka kubantu abaningi, kodwa izinwele ziyakhula futhi ngemva kokuphela kokwelashwa.
• Ikhanda elibuhlungu .
• Ukudla akunambitheki .
• Amehlo azwela ukukhanya kwelanga .
• Ukuphazamiseka okuncane kwesisu, njengokungagayeki kahle kokudla .
• Izinyembezi ezingavamile ziphuma emehlweni .

Lolu hlu aluhlanganisi yonke imiphumela emibi engaba khona. Uma ubona noma yini engavamile, khuluma nodokotela wakho ngayo.

Uyigcinaphi le mithi?

Lona akuyona imithi ongayigcina ekhaya. I-Fluorouracil (5-FU) inikezwa esibhedlela noma emtholampilo, ngakho akudingeki ukhathazeke ngokuyigcina.

Okokugcina, khumbula (Umyalezo Wokuya Ekhaya)

Lesi sihloko simane nje siyisifinyezo somuthi olwa nomdlavuza i-fluorouracil (5-FU). Sithemba ukuthi lokhu kuzokunikeza umbono ngalo muthi. Kodwa-ke, awuthathi indawo yokukhuluma nodokotela wakho, usokhemisi, noma omunye umhlinzeki wezempilo .

Uma unemibuzo mayelana nalomuthi, ukuthi usebenza kanjani, imiphumela emibi, noma yini enye, ungangabazi ukubuza ithimba lakho lezokwelapha . Balapha ukuzokusiza.

Ukwelashwa komdlavuza kungaba uhambo oluyinselele. Kodwa ngolwazi olufanele, isiqondiso esivela kudokotela wakho, kanye nokusekelwa ngumndeni wakho, ungabhekana nale nselele. Khumbula, awuwedwa .

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I- Fluorouracil, i-5-FU, umdlavuza, i-chemotherapy, imithi yomdlavuza, imiphumela emibi, ukwelashwa komdlavuza