Ingabe amehlo akho aphenduka aphuzi? Kungaba ushintsho oluncane esibindini: Ake sifunde nge-Gilbert's Syndrome!

Wake waphawula ukuthi amhlophe amehlo akho, futhi ngezinye izikhathi isikhumba sakho, siphuzi kancane? Noma ingabe udokotela ukutshelile ukuthi ukuhlolwa kwegazi lakho kubonisa amazinga aphezulu e-bilirubin? Ungase ukhathazeke. Kodwa ungakhathazeki, ngoba isikhathi esiningi akukubi kangako. Namuhla sizokhuluma ngesimo esinjalo, esibizwa ngokuthi i-Gilbert's Syndrome.

Iyini i-'Gilbert's Syndrome'?

Kalula nje, i-'Gilbert's Syndrome' yisimo sofuzo lapho isibindi sethu singakwazi ukucubungula kahle into ebizwa ngokuthi 'bilirubin'. Cabanga ngakho, lapho amangqamuzana egazi abomvu amadala emzimbeni wethu ewohloka, kukhiqizwa into ephuzi ebizwa ngokuthi 'bilirubin'. Lokhu kuwumkhiqizo ongcolile. Isibindi somuntu ophilile sithatha le 'bilirubin', siyishintshe, bese siyisusa emzimbeni.

Kodwa kubantu abane-Gilbert's Syndrome, isibindi asikhiqizi uhlobo olwanele lwe-enzyme esiza ekuqhekekeni kwe-bilirubin. Uma sikhuluma iqiniso, kukhona ukuntuleka okuncane ekukhiqizweni kwaleyo enzyme. Ngakho-ke kwenzekani-ke? Leyo bilirubin iyanqwabelana emzimbeni. Lapho izinga le-bilirubin egazini landa kanje, ngokwezokwelapha sikubiza ngokuthi i-hyperbilirubinemia.

Ngakho-ke, iyini le 'Bilirubin'?

I-Bilirubin, njengoba kushiwo ngaphambili, iwumbala ophuzi okhiqizwa lapho amangqamuzana ethu abomvu egazi amadala ephuka. Itholakala enyongweni yethu. Inyongo iwuketshezi olukhiqizwa yisibindi olusiza ekuncibilikiseni amafutha ekudleni esikudlayo. Njengoba wazi, isibindi siyisitho esibaluleke kakhulu ohlelweni lwethu lokugaya ukudla. Sihlunga ubuthi egazini, sigaye amafutha, futhi sigcine i-glucose, edingekayo ukuze kube namandla, njenge-glycogen.

Ivame kangakanani i-Gilbert's Syndrome?

Empeleni lokhu akuyona into engavamile njengoba ungase ucabange. Ezweni elifana ne-United States, kulinganiselwa ukuthi phakathi kuka-3% no-7% wabantu banalesi simo. Futhi, amadoda anamathuba amaningi okuthola i-'Gilbert's Syndrome' kunabesifazane. Ingathinta abantu banoma yimuphi ubudala nanoma yiluphi uhlanga.

Ubani ongaba ne-'Gilbert's Syndrome'? Yini ebangela lokhu?

I-Gilbert's Syndrome iyisimo sofuzo. Lokhu kusho ukuthi sidluliselwa kusuka kubazali kuya ezinganeni. Njengazo zonke izici zethu (isibonelo, umbala wesikhumba , umbala wezinwele, ukuphakama), sinqunywa izakhi zofuzo. Ngokufanayo, abantu abane-Gilbert's Syndrome bazuza ushintsho, noma ukuguquka kwezakhi zofuzo ezithile ezibizwa ngokuthi i-UGT1A1.

Uma sikhuluma iqiniso, i-'UGT1A1' gene enempilo ikhiqiza ama-enzyme esibindi aphula i-'bilirubin' eshiwo ngenhla bese eyisusa emzimbeni. Kodwa-ke, kubantu abanokuguqulwa kwe-'UGT1A1' gene, kukhiqizwa u-30% kuphela wenani elidingekayo lale enzyme. Ngenxa yalokho, i-'bilirubin' ayihlangani kahle ne-bile bese iphuma emzimbeni. Ngakho-ke, leyo 'bilirubin' eyengeziwe iqoqana egazini.

Ziyini izimpawu ze-'Gilbert's Syndrome'?

Ngokumangalisayo, cishe umuntu oyedwa kwabathathu abane-Gilbert's Syndrome akanazo nhlobo izimpawu. Bathola ngalesi simo ngengozi kuphela uma behlolwa igazi ukuze bathole okunye.

Kodwa-ke, phakathi kwalabo abathola izimpawu, uphawu oluvame kakhulu yi-jaundice, noma i-jaundice. Lokhu kubangelwa amazinga aphezulu e-bilirubin egazini. I-jaundice ingabangela isikhumba sakho kanye namehlo akho amhlophe ukuba aphenduke aphuzi. Kodwa khumbula, lokhu kuphuzi akulimazi ngempela.

Ngezinye izikhathi, abantu abane-jaundice noma i-Gilbert's Syndrome bangase babe nezimpawu ezifana nalezi:

• Umchamo omnyama noma indle enombala wobumba.
• Ubunzima bokugxila entweni ethile.
• Ukuzizwa unesizungu .
• Izinkinga zesistimu yokugaya ukudla: Isibonelo, ubuhlungu besisu, uhudo, isicanucanu.
• Ukuzizwa ukhathele kakhulu (ukukhathala).
• Izimpawu ezifana nomkhuhlane njengomkhuhlane kanye nokubanda.
• Ukudla akunambitheki.

Yiziphi izinto ezenza izimpawu ze-Gilbert's Syndrome zibe zimbi nakakhulu?

Izici ezilandelayo zingakhuphula izinga le-bilirubin egazini lomuntu one-Gilbert's Syndrome, okubangela i-jaundice :

• Ukuphelelwa amanzi emzimbeni: Uma ungaphuzi amanzi anele. Lokhu kungenzeka kakhulu ekushiseni kwezwe lethu.
• Ukuzila ukudla noma ukweqa ukudla: Izinto ezifana nokungadli isidlo sasekuseni noma ukudla isidlo sasemini sekwephuzile.
• Ukugula noma ukutheleleka: Ngisho nomkhuhlane noma olunye ukutheleleka kungabangela amazinga e-bilirubin akhuphuke.
• Ukuya esikhathini : Kwabesifazane, lezi zimpawu zingase zibonakale kakhulu ngesikhathi sokuya esikhathini.
• Ukuzikhandla ngokweqile: Uma usebenza kanzima ngaso sonke isikhathi, udlala, uvivinya umzimba, noma wenza umsebenzi onzima kakhulu.
• Ukucindezeleka: Ingcindezi ephakamayo njengoba izivivinyo zisondela kanye nemithwalo yemfanelo yomsebenzi iyanda nayo inomthelela.

Cabanga nje, kunomfana omncane ogama lakhe linguNimal. Akazi ukuthi une-'Gilbert's Syndrome'. Ngolunye usuku, wadlala ikhilikithi nabangani bakhe, wajuluka kakhulu, futhi akaphuzanga manzi anele. Ngakusasa ekuseni, unina uqaphela ukuthi amehlo kaNimal aphuzi kancane. Kulapho emkhombisa khona udokotela kuphela lapho ethola khona ukuthi une-'Gilbert's Syndrome', nokuthi amazinga akhe e-bilirubin akhuphukile ngenxa yokukhathala kosuku nokuntuleka kwamanzi.

I-Gilbert's Syndrome ihlolwa kanjani?

I-Gilbert's Syndrome iyisifo esibangelwa ufuzo, okusho ukuthi sikhona kusukela ekuzalweni. Kodwa sivame ukungatholakali kuze kube yilapho ukuhlolwa kwegazi kubonisa amazinga aphezulu e-bilirubin. Ngokuvamile sitholakala sisebancane, eminyakeni yokweshumi noma ekuqaleni kweminyaka yokweshumi nambili, lapho kwenziwa ukuhlolwa kwegazi ngenxa yento ethile.

Ngaphezu kokuhlolwa kwegazi, ungase ube nokuhlolwa okufana nalokhu:

• Ukuhlolwa kokusebenza kwesibindi: Lokhu kuhlola ukuthi isibindi sakho sisebenza kahle kangakanani nokuthi amazinga akho e-bilirubin angakanani.
• Ukuhlolwa kwezakhi zofuzo: Lokhu kunganquma ngokunembile ukuthi ngabe kukhona yini ukuguqulwa kwezakhi zofuzo okubangela i-'Gilbert's Syndrome'.

Yiziphi izinkinga ezingaba khona ze-Gilbert's Syndrome?

Nansi into ebalulekile: I-Gilbert's Syndrome iyisimo esingesihle neze. Ayibangeli izinkinga zesikhathi eside noma izinkinga ezinkulu zempilo. Ngakho-ke akukho okufanele ukhathazeke ngakho.

Ingabe ikhona indlela yokwelapha i-Gilbert's Syndrome? Iphathwa kanjani?

Ukuba namehlo aphuzi, noma i-jaundice, kungaba yinto ekhathazayo ngempilo yengqondo. Ungase ucabange izinto ezinjengokuthi, "O, amehlo ami aphuzi, ubani ozocabangani?" Kodwa-ke, i-jaundice noma i-Gilbert's Syndrome azidingi ukwelashwa okukhethekile.

Lokhu kufana nombala wesikhumba sethu. Ezinye zinhle kakhulu, ezinye zimhlophe. Akusona isifo. Kunjalo-ke.

Ingabe i-Gilbert's Syndrome ingavinjelwa?

Njengoba i-Gilbert's Syndrome iwufuzo, ayikho indlela yokuyivimbela.

Kuyini ukubikezela komuntu one-Gilbert's Syndrome?

Lokhu futhi kuyizindaba ezinhle kakhulu. Abantu abane-'Gilbert's Syndrome' bangaphila impilo ende nenempilo ngaphandle kwezinkinga. Abanazo izinkinga zempilo zesikhathi eside ngenxa yalesi simo.

Kufanele ubonane nini nodokotela mayelana ne-Gilbert's Syndrome?

Nakuba lokhu ngokuvamile kungadingi ukwelashwa okukhethekile, kuwumqondo omuhle ukubona udokotela uma uqhubeka nokuba nezimpawu ezinjengalezi:

• Izinkinga zokugaya ukudla eziqhubekayo (isib., izinhlungu zesisu, isifo sohudo).
• Umchamo omnyama noma indle enombala wobumba .
• Umkhuhlane kanye nokubanda.
• Ukuphuzi okuqhubekayo noma okuvamile kwesikhumba noma amehlo (i-jaundice) .

Yimiphi imibuzo okufanele ngiyibuze udokotela wami mayelana ne-Gilbert's Syndrome?

Uma uthola ukuthi unesifo sikaGilbert, kuvamile ukuba nemibuzo eminingi. Ungase ufune ukubuza udokotela wakho izinto ezifana nalezi:

• Kungani ngathola i-'Gilbert's Syndrome'?
• Ingabe ngidinga ukwelashwa ngalokhu?
• Yini engingayenza ukuze ngivimbele i-jaundice?
• I-jaundice ihlala isikhathi esingakanani?
• Ingabe kufanele ngithole ukuhlolwa kofuzo ukuze kubonakale ukuthi amanye amalungu omndeni wami anayo yini i-Gilbert's Syndrome?
• Ingabe kufanele ngikhathazeke ngezinkinga? (Siyazi ukuthi le inqubo ayinangozi eningi, kodwa kuhle ukukwazi.)

Okokugcina, izinto ezimbalwa okufanele uzikhumbule (Umyalezo Wokuya Ekhaya)

I-Gilbert's Syndrome yisimo esibucayi kakhulu esingadingi ukwelashwa. Nakuba ukuphuzi kwamehlo nesikhumba ngezikhathi ezithile kungaba yinto ecasulayo, i-jaundice ayibangeli zingozi empilweni. Lokhu kuphuzi kwesikhumba namehlo kuvame ukuphela ngokwakho . Udokotela wakho angakweluleka ngezindlela zokunciphisa amathuba okuba ne-jaundice ehlotshaniswa ne-Gilbert's Syndrome. Ngakho-ke, ungacabangi kakhulu ngakho. Phila impilo ejabulisayo!

I- Gilbert's Syndrome, i-bilirubin, i-jaundice, isibindi, izakhi zofuzo, i-UGT1A1, i-jaundice, isibindi, i-bilirubin, izakhi zofuzo