Zingaki izinhlobo zamagciwane ezihlala emizimbeni yethu singazi? Igciwane le-JC lingenye yazo. Eqinisweni, leli gciwane lihlala emizimbeni yabantu abadala abangaphezu kwengxenye emhlabeni. Kodwa into emangalisayo ukuthi, alibangeli monakalo noma inkinga kubantu abaningi. Ngakho-ke, namuhla sizokhuluma ngokuningiliziwe ngokuthi lokhu kuyini ngempela, ukuthi kuba nini inkinga, nokuthi kufanele sesabe yini.
Iyini ngempela igciwane le-JC?
Kalula nje, igciwane le-JC liyigciwane elivame kakhulu. Laqala ukutholakala ngo-1971. Udokotela wathola leli gciwane ebuchosheni bendoda ehlushwa umdlavuza obizwa ngokuthi i-Hodgkin's lymphoma. Leli gciwane liqanjwe ngegama lesiguli (uJohn Cunningham).
Kodwa ochwepheshe abakaqiniseki ukuthi lisakazeka kanjani lisuka komunye umuntu liye komunye. Kodwa-ke, abantu abaningi bakholelwa ukuthi igciwane lingena emizimbeni yethu lapho sisebancane ngamanzi noma ngokudla okungcolile. Uma selingaphakathi, igciwane lingahlala lilele emgudwini womchamo, emnkantsheni, emathonyeni, noma ebuchosheni iminyaka eminingi, kungadali zinkinga. Ngenxa yalokho, abantu abaningi abazi nokuthi banalo igciwane.
Ngakho-ke ubani osengozini yalokhu?
Nansi into ebalulekile. Uma nje amasosha akho omzimba ephilile futhi enamandla, igciwane le-JC ngeke likukhathaze. Kufana nokulala nje.
Kodwa-ke, uma ngesizathu esithile amasosha omzimba womuntu eba buthakathaka kakhulu , lelo gciwane elilele livuka ngokuzumayo bese liqala ukusebenza.
Uma igciwane liqala ukusebenza ngale ndlela, lingabangela ukutheleleka kobuchopho okubi kakhulu okubizwa ngokuthi i-Progressive Multifocal Leukoencephalopathy , noma i-PML .
Kuyini i-PML?
Lokhu kulimaza isembozo esivikelayo esizungeze amangqamuzana ethu ezinzwa . Kufana nesembozo sepulasitiki esincibilika ngocingo lukagesi. Lokhu kuphazamisa ngokuphelele inqubo yokuthumela imiyalezo ngemizwa. Lokhu kungaholela ekukhubazekeni okungapheli futhi ngezinye izikhathi ngisho nokufa .
Ingozi ephezulu kakhulu yokuthola i-PML yile:
- Kwabagulayo abane-HIV/AIDS .
- Isifo sikaHodgkin), abantu abanezimo zomdlavuza ezifana ne-leukemia kanye ne-lymphoma.
- Kubantu abanezimo ezifana ne- Multiple Sclerosis (MS) , i-Rheumatoid Arthritis , noma labo abathatha izinhlobo ezithile zemithi yokucindezela amasosha omzimba ngemva kokufakelwa isitho .
Ziyini izimpawu ze-PML?
Lezi zimpawu zivame ukuqala ngokushesha futhi zibe zimbi kakhulu ngokuhamba kwesikhathi. Izimpawu zingahluka kuye ngendawo yobuchopho eyonakele. Kodwa-ke, lezi yizimpawu ezivame kakhulu.
| Isibonakaliso | Incazelo |
|---|---|
| Ukungakhululeki | Izinto ezinjengobunzima bokwenza izinto, ukukhubeka lapho uhamba, nokuwa ezandleni. |
| Ubuthakathaka obuya buba bubi kakhulu | Ubuthakathaka engalweni, emlenzeni, noma ohlangothini olulodwa lomzimba bukhula kancane kancane. |
| Izinguquko ebuntwini | Izinguquko ezifana nentukuthelo engazelelwe, ukucasuka, kanye nokulahlekelwa inkumbulo. |
| Inkinga yokukhuluma | Amagama ayaphithana, futhi angikwazi ukusho kahle engifuna ukukusho. |
| Izinkinga zokubona | Ukubona kuyafiphala, kanye nezinkinga ezifana nokubona izinto ezimbili ngesikhathi esisodwa. |
Ukuthola kanjani lokhu kahle?
Okokuqala, ungahlolwa ukuze ubone ukuthi unegciwane le-JC. Lokhu kuhilela ukuthatha ukuhlolwa kwegazi noma isampula yezicubu . Lokhu kubaluleke kakhulu uma uthatha imithi ecindezela amasosha omzimba wakho .
Kodwa-ke, uma udokotela wakho esola ukuthi une-PML, inqubo yokuhlola ihlukile.
1. Ukuskena kwe-MRI: Ukuhlolwa kokuqala ozokwenza ukuskena kwe -MRI (Magnetic Resonance Imaging) . Lokhu kusebenzisa omaginethi abanamandla namagagasi omsakazo ukuthatha izithombe ezinemininingwane yobuchopho bakho nokubheka amaphethini ezicutshini zobuchopho ajwayelekile kwi-PML.
2. Ukuthepha Komgogodla: Okulandelayo, udokotela wakho angase anqume ukwenza ukuthepha komgogodla (ukubhoboza i-lumbar) . Ungakhathazeki, lokhu kuhilela ukuthatha inalithi encane bese uthatha inani elincane loketshezi lomgogodla emhlane wakho ongezansi. Lolu ketshezi luhlolwa ukuthi lukhona yini igciwane le-JC. Uma igciwane le-JC litholakala kulolu ketshezi, kuqinisekisa ukuthi kukhona i-PML.
3. I-Brain Biopsy: Uma ukuhlolwa okungenhla kungakabi yimpumelelo, kungase kudingeke ukuthi kuthathwe ingxenye encane yezicubu zobuchopho ukuze ihlolwe (i-biopsy).
Ubudlelwano phakathi kwemithi esetshenziswa ukwelapha izifo ezithile kanye negciwane le-JC
I-Multiple Sclerosis (MS) kanye nesifo sikaCrohn
Eminye imithi esetshenziselwa ukwelapha izimo ezifana ne -Multiple Sclerosis (MS) kanye ne-Crohn's Disease (isibonelo, i-Natalizumab, i-Dimethyl fumarate, i-Fingolimod, i-Ocrelizumab ) itholakale ihlotshaniswa ne-PML.
Ngakho-ke, ngaphambi kokuqala lolu hlobo lomuthi, udokotela wakho uzokuvivinya nakanjani ukuze abone ukuthi unegciwane le-JC. Ungase ukwazi ukuthatha lo muthi noma ngabe unegciwane, kodwa kufanele uxoxe ngezingozi nezinzuzo nodokotela wakho ngaphambi kokwenza isinqumo.
I-HIV/AIDS
Eminye imithi yesimanje enikezwa abantu abane-HIV/AIDS iyasiza ekuqiniseni amasosha omzimba. Lokhu kube usizo olukhulu ekuvimbeleni ukuvela kwe-PML egciwaneni le-JC. Ngenxa yalokho, ukwanda kwe-PML phakathi kweziguli ezine-HIV/AIDS kwehle kakhulu eminyakeni yamuva.
Yiziphi izindlela zokwelapha i-PML?
Okwamanje, akukho muthi othize ovunyelwe ukwelapha i-PML ngokuphelele, futhi ososayensi basacwaninga ngalokhu.
Ukwelashwa okungcono kakhulu okutholakalayo njengamanje ukusiza amasosha omzimba ukulwa naleli gciwane ngokwawo ngokulivuselela. Isibonelo, uma umuntu ethatha umuthi ocindezela amasosha omzimba wakhe, udokotela wakhe angase anqume ukuwuyeka noma ukuwushintsha lowo muthi.
Umlayezo Wokuya Nawe Ekhaya
- Igciwane le-JC liyigciwane elivame kakhulu elingenangozi kubantu abaningi. Ngakho-ke ungalisabi ngokungadingekile.
- Ingozi yangempela yalokhu ingabantu abanezivikeli mzimba ezibuthakathaka kakhulu, abangathola ukutheleleka kobuchopho okukhulu okubizwa ngokuthi i-PML.
- Uma uzwa izimpawu ezifana nobuthakathaka obungavamile, ubunzima bokuhamba noma ukukhuluma, noma ushintsho olusheshayo ebuntwini, ikakhulukazi uma uphuza imithi ecindezela amasosha omzimba wakho, bona udokotela wakho ngokushesha.
- Ngaphambi kokuqala imithi ethile yezifo ezifana ne-MS kanye ne-Crohn's, qiniseka ukuthi ukhuluma nodokotela wakho ngengozi yegciwane le-JC kanye ne-PML.
- Uma unemibuzo noma ukungabaza ngalokhu, into engcono kakhulu ongayenza ukukhuluma nodokotela wakho ngakho ngokucacile bese uthola ulwazi.
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