Ake sifunde ngemithi ekhethekile (i-Leukotriene Modifiers) elawula ukungezwani komzimba kanye ne-asthma.

Ukuthimula njalo, ikhala eligelezayo, futhi ngezinye izikhathi kunzima ukuphefumula... Ziyacasula kangakanani lezi zinto? Abantu abaningi bahlushwa yi -allergies kanye ne-asthma. Ngakho-ke namuhla sizokhuluma ngeklasi elisha lemithi esetshenziswa ukulawula lezi zimo. Lezi zibizwa ngokuthi 'ama-Leukotriene Modifiers'.

Ziyini i-Leukotriene Modifiers? Zisebenza kanjani?

Ngaphambi kokuba siqonde lo muthi, ake sifunde ngento encane eyenzekayo emizimbeni yethu.

Kalula nje, uma into ethile esinayo i-allergy, okungukuthi, i-allergen - isibonelo, uthuli, impova - ingena emzimbeni wethu, amasosha omzimba ethu ayasabela kuyo. Njengengxenye yale mpendulo, umzimba wethu ukhiqiza amakhemikhali abizwa ngokuthi 'ama-leukotriene' .

Leli khemikhali, elibizwa ngokuthi i-leukotriene, liyimbangela yezimpawu eziningi zokungezwani komzimba kanye ne-asthma . Lokhu kungenxa yokuthi:

• Imigudu yomoya eya emaphashini iyancishiswa, okwenza kube nzima ukuphefumula (ukuminyana).
• I-mucus kanye nolunye uketshezi kukhiqizwa kakhulu ngaphakathi kwemigudu yomoya.
• Izicubu zekhala ziyavuvukala futhi impumulo iyavaleka.

Ngakho-ke, lokho okwenziwa yi-Leukotriene Modifiers ukuvimba isenzo sekhemikhali ebizwa ngokuthi i-leukotriene. Ukuze kube sobala, ivimbela le khemikhali ukuthi ingasebenzi namaseli emzimbeni. Kufana nokuvala umnyango. Futhi lokho kulawula ukuvela kwalezo zimpawu ezicasulayo esikhulume ngazo ngaphambili. Kodwa khumbula, lezi ngokuvamile aziyona indlela yokwelapha yokuqala.

Lo muthi usiza kanjani ukulawula izimpawu zokungezwani komzimba?

Ukuthimula, ikhala eligobhozayo, ikhala eligobhozayo, kanye nekhala elicijile kuyizimpawu ezivamile zokungezwani komzimba (i-allergic rhinitis). Ngaphezu kwalokho, amehlo alumayo, avuvukile, anamanzi (i-allergic conjunctivitis) kanye nomphimbo obuhlungu nakho kungavela. Labo ababhekana nalezi zimo bayazi ukuthi kunzima kangakanani ukuphila nazo.

Ama-leukotriene modifier, avimba ukusebenza kwe-leukotrienes, awusizo olukhulu ekulawuleni ukuthimula nokulunywa okwenzeka ezigabeni zokuqala zokungezwani komzimba, kanye nokuminyana kwamakhala okwenzeka ngemva kwesikhashana.

Ungayisebenzisa kanjani le mithi ye-asthma?

Le mithi isetshenziswa kakhulu ekuvimbeleni nasekulawuleni i-asthma isikhathi eside. Iphinde inconywe ekuvimbeleni i-asthma ebangelwa ukuvivinya umzimba.

Kodwa-ke, lokhu kubaluleke kakhulu : Lo muthi awukwazi ukusetshenziswa wodwa ukulawula ukuhlaselwa yi-asthma okunamandla. Lokhu kusho ukuthi ukuthatha lo muthi ngeke kusize uma i-asthma inzima kakhulu futhi unenkinga yokuphefumula. Ngezikhathi ezinjalo, kufanele usebenzise i-inhaler esebenza ngokushesha, ekhulula umkhuhlane. Lo muthi we-Leukotriene Modifier ubalulekile ekugcineni lesi sifo silawulwa.

Yiziphi izidakamizwa ezivame kakhulu ezisetshenziswa eSri Lanka ezibizwa ngokuthi i-Leukotriene Modifiers?

Nakuba imithi ye-asthma efana ne-`zafirlukast (Accolate)` kanye ne-`zileuton (Zyflo)` ingeyaleli qembu, umuthi osetshenziswa kakhulu eSri Lanka, ovunyelwe kokubili i-rhinitis ye-allergy kanye ne-asthma, yi -`montelukast` . Ungase ulazi ngegama lomkhiqizo elithi `Singulair`.

Nansi indlela esebenza ngayo i-montelukast njengoba itholakala ocwaningweni:

Ngakho-ke, odokotela bavame ukuncoma ukuzama i-intranasal steroid spray ngaphambi kokunikeza i-Leukotriene Modifier, njengoba imiphumela yayo ingaba namandla kakhulu.

Ingabe ikhona imiphumela emibi?

Njenganoma yimuphi umuthi, abanye abantu bangase babe nemiphumela emibi. Evame kakhulu ihlanganisa:

• Ukuzizwa sengathi unomkhuhlane
• Ikhanda elibuhlungu
• Isisu esibuhlungu
• Isicanucanu noma ukuhlanza
• Ukuminyana kwekhala

Into okufanele uyiqaphele kakhulu!

I-FDA ikhiphe isixwayiso mayelana nengozi yemiphumela emibi yezempilo yengqondo engathi sína ngomuthi i-'Montelukast.' Nakuba lokhu kungavamile kakhulu , kubalulekile ukukuqaphela.

Uma wena noma ingane yakho nizwa noma yiziphi zalezi zimpawu ngesikhathi nithatha lo muthi, yekani ukuthatha umuthi ngokushesha bese wazisa udokotela wakho:

• Ukungaphumuli, ukucasuka
• Amaphupho angajwayelekile noma asabekayo
• Ukucindezeleka
• Imicabango yokuzibulala

Uma ubona into efana nale, ungalibali. Funa iseluleko sezokwelapha ngokushesha.

Ubani okungafanele asebenzise lo muthi?

• Izingane ezincane: Ukuphepha kwale mithi ye-asthma ezinganeni ezingaphansi kwezinyanga ezingu-12 ubudala kanye ne-rhinitis engapheli ye-allergy ezinganeni ezingaphansi kwezinyanga eziyisithupha ubudala akukaqinisekiswa. Ngakho-ke, ungayiniki izingane ezincane le mithi ngaphandle kweseluleko sikadokotela.
• Omama abakhulelwe nabancelisayo: Uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa, kufanele nakanjani ukhulume nodokotela wakho ngaphambi kokuthatha lo muthi.

Lomuthi uza ngesimo samaphilisi, amaphilisi ahlafunwayo, kanye nama-granule. Kungathatha noma yikuphi kusukela ezinsukwini ezintathu kuya emavikini amabili ukuthola izinzuzo ezigcwele zalomuthi. Ngakho-ke ungayeki ukuwuthatha ngoba nje ungazizwa ungcono ezinsukwini ezimbili noma ezintathu. Sebenzisa isikhathi sonke njengoba udokotela wakho ekuyalele.