He iti te wehi o tātou katoa mō te ngaronga o te mahara i a tātou e pakeke haere ana, kāore? Ina koa mēnā kua pāngia tētahi o tō whānau e te mate pēnei i a Alzheimer 's, tera pea kei roto i tō hinengaro te pātai 'Ka pāngia hoki ahau?'. He aha te pānga o ō tātou ira ki tēnei? E kī ana ngā rangahau hou he hononga kaha ake i waenga i tētahi ira motuhake e kiia nei ko APOE4 me te mate a Alzheimer's i tō whakaaro o mua. Nō reira, i tēnei rā, me kōrero tātou mō tēnei, mēnā ka pā ki a koe, me ā tātou mahi hei ārai.
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He aha rawa te ingoa o tēnei ira ko APOE4?
He whakarāpopototanga noa iho, he ira te APOE i roto i tō tātou tinana. Ko tana mahi matua he kawe i ngā ngako , pērā i te cholesterol, i waenga i ō tātou pūtau (te kawe lipid). Whakaarohia ngā pūtau i roto i tō tātou tinana he whare iti. Me whai ngako ēnei whare hei mahi, hei hanga i aua mea, hei whakaputa pūngao hoki. He rite te ira APOE ki tētahi 'ratonga tuku' e kawe mai ana i ēnei ngako ki roto, ki waho hoki i ngā pūtau. Ki te kore tēnei mahi e mahi tika, ka puta pea ngā raruraru, inā koa i roto i ngā pūtau roro.
Kei te katoa tēnei ira APOE?
Ae, kei roto i ō tātou tinana katoa tēnei ira APOE. Engari kāore i te rite. He rite tonu ki te āhua, ahakoa i roto i te 'ratonga tuku' kotahi, he tino mātau ētahi kaimahi, he noa ētahi, ā, he mangere ētahi. E toru ngā momo matua. Kia tirohia tātou he aha ngā rerekētanga.
| Momo Ira | He aha te mea ka tupu (Pānga) |
|---|---|
| APOE2 | Koinei te momo pai rawa atu . Ki te mea kei a koe tēnei, he iti noa iho ngā raruraru ka pā ki te pākia o te ngako. E kiia ana hoki ka whakaratohia he ārai ki te mate a Alzheimer. |
| APOE3 | Koinei te momo noa . He tokomaha ngā tāngata e pāngia ana e tēnei. Kāore he pai, he kino rānei. Kāore e whakanui ake i te mōrearea, kāore hoki e whakarato i te tiakitanga. |
| APOE4 | Koinei te raruraru . Kāore e mahi tika ana i tana mahi ki te kawe i te ngako. Mēnā kotahi, e rua rānei ngā tārua o tēnei ira ka nui ake te tūponotanga o te whakawhanake i te mate a Alzheimer. |
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Check Availability →He aha te kōrero a te rangahau hou?
I whakaaro mātou i mua ko te APOE4 he 'tūponotanga' noa iho mō te mate a Alzheimer. Arā, ki te pāngia koe e tēnei mate, ehara i te mea ka pāngia koe e te mate, engari he nui ake te tūponotanga.
Engari e kī ana tēnei rangahau hou, ehara i te mea he take mōrearea noa iho te whai i ngā tārua e rua o te ira APOE4, engari he momo ira anō pea nō te mate a Alzheimer. Ko te tikanga he nui ake te mōrearea o te hunga whai ira e rua ki te pangia e te mate. Ā, ka tīmata pea ngā tohu i te wā taitamariki tonu.
E mōhiotia whānuitia ana ko ngā ira e puta ai te mate a Alzheimer ko (APP), (PSEN1) me (PSEN2). He tino onge ēnei. Engari kua tata ake te ira APOE4 ki a rātou nā tēnei rangahau. Kua kitea e rātou e 95% o te hunga e rua ngā kape o te APOE4 he nui rawa ngā taumata o te (beta amyloid), he pūmua kino e pā ana ki te mate a Alzheimer, i roto i te roro i te 65 tau te pakeke.
Ki te mea kei a koe te ira APOE4, tera pea ka pāngia koe e te mate a Alzheimer?
Kāo. Kāore i te tino taurangihia. Engari he tino teitei te mōrearea. He rite ki te taraiwa tere rawa i tētahi motuka, ā, ka nui ake te tūponotanga o te aituā. Kāore e tupu, engari ka nui ake te tūponotanga. Tata ki te 2% o te taupori kei a rātou ngā tārua e rua o te ira APOE4. I waenga i te 15% me te 25% he tārua kotahi.
Ka taea e au te whakamātautau mēnā kei a au tēnei ira?
Ae, kei reira ngā whakamātautau ira mō tēnei. Engari ehara tēnei i te whakamātautau e tohua ana e tō tākuta, ā, ka taea te mahi ngāwari i roto i te hōhipera. Kāore tēnei i te tino kitea i Sri Lanka. Ahakoa i ngā whenua ke, he onge te hipokina e te inihua.
Ka taea te utu i ēnei whakamātautau mā roto i ngā whare tūmataiti. Nāu ake te whakatau mēnā ka whiriwhiria e koe tēnei, kāore rānei. Mena he maha ngā mema o tō whānau e pāngia ana e te mate a Alzheimer, me kōrero pea koe ki tētahi tākuta, ā, me whakatau koe mō tēnei.
Ahakoa te mōrearea, me aha tātou hei ārai i te mate?
Anei te wāhanga nui. Kāore e taea e tātou te whakarerekē i ō tātou ira. Engari ka taea e tātou te whawhai ki te mōrearea e pā mai ana. Ahakoa kāore e taea e tātou te whakakore i te mate ina tino whanake, ka taea e tō tātou momo noho te whakaroa , te ārai rānei i tōna putanga mai.
Ko te mea nui ko te hanga i te manawanui o te roro. Whakaarohia tō roro he whare nui i hangaia ki runga i ngā pou. I muri i te 20 tau, ko ngā mea e mahia ana e tātou ka wawahi i ēnei pou, ka hanga rānei i ngā pou hou ka whakapakari ake.
1. Me tīmata tātou ki te kai totika.
Kua whakaatuhia e ngā rangahau he maha ngā wā ka taea e te kai tipu te whakaiti i te mōrearea o te mate a Alzheimer mā te 50%. Arā, he kai e nui ana i ngā huawhenua, ngā hua, ngā pīni, ngā nati, me ngā witi katoa . He pai hoki te kai Mediterranean .
2. Ehara i te mea ko te hikoi anake te kaupapa o te whakakori tinana.
He taputapu kaha anō te whakakori tinana hei whakaiti i te mōrearea. Engari kāore e ranea te hikoi noa i te māra. Ko te momo whakakori tinana e werawera ai koe, e ngenge ai hoki te tinana, ā , he tino mahi tēnei ki tō roro. He mea nui rawa te whakakori tinana, pērā i te hiki taumaha . I whakaatuhia e tētahi rangahau ko te hunga whai mate wareware i mahi i ngā whakakori tinana whakapakari waewae i whakaiti i tō rātou mōrearea ki te pangia e te mate mā te 40%.
3. Whakakorikorihia tō roro hoki
He mea nui te whakakorikori hinengaro, pērā i te whakakorikori tinana. Ka whakapakari tēnei i ngā hononga i waenga i ngā pūtau e kiia nei ko ngā neuron i roto i te roro.
- Akohia tētahi mea hou (he reo, he taonga puoro).
- Whakaotihia ngā panga, Sudoku, me ētahi atu.
- Tomo hōhonu ki roto i tētahi mahi whakangahau e arohaina ana e koe.
- Ngā wero hou.
Ngā mea e tika ana kia mōhio te katoa mō ngā ira, ahakoa kāore rātou e mōhio
Kāore te mate a Alzheimer e tīmata i te tohu tuatahi o te ngaronga o te mahara. Ko ngā huringa mate i roto i te roro i puta mai i te mate ka tīmata i te 20-30 tau i mua i te putanga mai o ngā tohu tuatahi .
Ko te tikanga o tēnā, me whakaaro tātou katoa, kei roto i ō tātou tau 30, 40, me 50, ki te hauora o ō tātou roro ināianei tonu.
Kōrero ki tō tākuta, kia mōhio ai koe ki ō taumata cholesterol, te toto toto tiketike, me ngā uara whakamātautau HbA1c, e tohu ana i tō āhua mate huka. Ko te whakahaere i ēnei tetahi o ngā haumitanga nui rawa atu ka taea e koe te mahi hei tiaki i tō roro.
Karere Tangohia ki te Kāinga
- He tino kaha te tūponotanga o te mate a Alzheimer ki te whai i te ira APOE4. Mēnā e rua ngā tārua o taua ira, ka nui ake te tūponotanga kia pāngia koe e te mate.
- Heoi, ehara i te mea he taurangi 100%. Ahakoa he mōrearea ira, ka taea te whakahaere me te whakaroa i te mate mā te huri i te momo noho.
- Ko te kai pai, te whakakori tinana kaha, me ngā mahi hinengaro e wero ana i te roro, koinā āu patu tino kaha.
- Kaua e tatari kia kaumātuatia koe ki te whakaaro mō te hauora o te roro. Tīmata mai i te tamarikitanga.
- Kōrero ki tō tākuta mō tō toto totoka, tō cholesterol, me tō huka, kia mau tonu hoki ki ngā taumata hauora.
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