Khawucinge nje, ugqirha wakho ukrokrela ukuba unengxaki ngezintso zakho. Ngoko ke, ukucela ukuba wenze uvavanyo lwegazi ukuze kuhlolwe ukusebenza kwezintso zakho. Ubuya kumangaliswa ukuba ebekuxelela ukuba inani elikwingxelo liyahluka ngokuxhomekeke kuhlanga lwakho, akunjalo? "Imisebenzi yezintso zam iyahluka njani ngokuxhomekeke kuhlanga lwam?" Usenokuba uzibuza. Le yingxaki enkulu ebiqhubeka kwihlabathi lezonyango ixesha elide, kwaye ngoku iyalungiswa. Namhlanje siza kuthetha ngayo.
Yintoni le equation elinganisa ukusebenza kwezintso?
Izintso zethu zifana nezihluzo ezimbini ezinamandla emzimbeni. Umsebenzi ophambili wezintso kukucoca inkunkuma engafunekiyo egazini nokugcina umzimba ucocekile. Ngoko ke, enye yeendlela eziphambili zokulinganisa ezisetyenziswa ngoogqirha ukujonga impilo yezintso yi -eGFR . Oko kumela i-Glomerular Filtration Rate eqikelelweyo .
Ngamafutshane, ilinganisa indlela izintso zakho ezicoca ngayo igazi lakho ngokukhawuleza nangendlela eyiyo. Ngenxa yokuba kunzima ukulinganisa oku ngokuthe ngqo, siqikelela sisebenzisa i-mathematical equation esebenzisa izinto ezifana nenqanaba lenkunkuma ebizwa ngokuba yi-creatinine egazini lakho, ubudala bakho, kunye nesini sakho.
Ukwehla kwexabiso le-eGFR kubonisa ukuba izintso azisebenzi kakuhle. Eli xabiso libaluleke kakhulu enceda oogqirha ukuba bagqibe ukuba umntu kufuneka aqale i-dialysis okanye afakelwe izintso.
Ingxaki iqale phi? 'Uhlanga' lwaba njani yinxalenye ebalulekileyo?
Kangangexesha elithile, bekukho utshintsho olumangalisayo kule equation ye-eGFR: 'uhlanga' . Kodwa oku bekungasebenzi kuzo zonke iintlanga. Bekusebenza kuphela xa umntu ezichonge njengo "mntu omnyama."
Oko kukuthi, umntu omhlophe kunye nomntu omnyama abaneminyaka efanayo, isini, kunye nenqanaba le-creatinine bafumana amaxabiso amabini e-eGFR. Ukuba umntu omnyama wayengumntu omhlophe, i-equation yayilinyusa elo xabiso ngokungekho mthethweni.
Kwenzeke ntoni? I-eGFR ibonise ukuba ukusebenza kwezintso zomntu omnyama kungcono kunokuba kunjalo ngokwenene. Ngenxa yoko, balibaziseka ekufumaneni unyango abaludingayo, njengokuqala i-dialysis okanye ukufakwa kuluhlu lwabantu abafakelwa izintso. Oku kwakungalungi okukhulu, okungacwangciswanga.
| I-eGFR equation endala (kuquka uhlanga) | I-eGFR equation entsha (engenalo uhlanga) |
|---|---|
| Inqanaba le-creatinine, ubudala, isini kunye 'nohlanga' (nokuba lumnyama okanye alumnyama) ziqwalaselwe ekubalweni. | 'Uhlanga' lususiwe ngokupheleleyo ekubalweni. Ngoku kuqwalaselwa kuphela inqanaba le-creatinine, ubudala kunye nesini. |
| Kuboniswe ukuba amaxabiso e-eGFR kwizigulane ezimnyama anyuswe ngokungekho mthethweni. | Ibala i-eGFR ngendlela elinganayo, isebenzisa umlinganiselo ofanayo kwizigulana zazo zonke iintlanga. |
| Oku kukhokelele ekungalinganini nasekulibazisekeni kokunika unyango kunye nokucwangciswa kokufakelwa kwezintso. | Inceda ekunciphiseni ukungalingani kwiindlela zokuthumela abantu abaya kunyango. |
Kutheni igama elithi 'isizwe' lafakwa kwasekuqaleni?
Oku kungenxa yophando olwenziwe ngeminyaka yoo-1990. Uphononongo olwenziwe ngelo xesha (Ukuguqulwa kokutya kwiSifo sezintso - uphando lwe-MRRD) lufumanise ukuba abantu abamnyama babenamanqanaba aphezulu e-creatinine egazini kunabantu abamhlophe. Bathi oku kubangelwa yinkolelo endala, ngoku ephikiswa yisayensi yokuba "abantu abamnyama ngokubanzi banemisipha emininzi kunabantu abamhlophe."
Ngelo xesha, ukubandakanywa kwabantu abamnyama kuphando kwakujongwa njengento enkulu, kodwa namhlanje siyaqonda ukuba 'uhlanga' aluyonto yendalo, kodwa lulwakhiwo loluntu.
“Xa sifundisa abafundi bethu bezonyango izibalo ezisekelwe kubuhlanga, sibafaka ingcamango engeyonyani yokuba uhlanga luyinto ebangela izifo ngokwebhayoloji. Kodwa akunjalo,” utshilo uGqr. Paul Palewski, umongameli weNational Kidney Foundation.
Uhambo lokulungisa le mpazamo
Ngethamsanqa, kwiminyaka yakutshanje, abafundi bezonyango, oogqirha, iingcali zezifo zengqondo , kunye nabalweli bamalungelo ezigulane baqalise ukubuza lo mba. “Ukuba akukho siseko sebhayoloji sale nto, kutheni sibaphatha ngendlela eyahlukileyo abantu abamnyama nabangengobantu abamnyama?” babuza.
Ngenxa yoko , iNational Kidney Foundation kunye neAmerican Society of Nephrology badibene ukuze benze iqela elisebenzayo lezigulane, izazinzulu kunye noogqirha. Ngenxa yomsebenzi wabo onzima, ngo-2021, kwaveliswa ii-equations ezimbini ezintsha ze-eGFR kwihlabathi elasusa ngokupheleleyo i-'race' factor .
1. I-equation yokuqala: Ngokufanayo neyakudala, isebenzisa inqanaba le-creatinine kuphela (kodwa ngaphandle 'kohlanga').
2. I-equation yesibini: Ukongeza kumanqanaba e-creatinine, kusetyenziswa nenye i-chemical marker ebizwa ngokuba yi -cystatin C. Nangona oku kuchanekile ngakumbi, i-equation yokuqala iyacetyiswa kuba uvavanyo lwe-cystatin C alufumaneki kuzo zonke iilabhoratri kwihlabathi kwaye lubiza kakhulu.
Olu tshintsho lwenzeka ngokukhawuleza kakhulu kwicandelo lezonyango kwihlabathi liphela. Kuyachulumancisa ngokwenene ukuba utshintsho oluthathe iminyaka elishumi lwenzeka kwiinyanga ezimbalwa ezizayo.
Kutheni lo mahluko ubalulekile kuthi?
Usenokucinga ukuba, le yingxaki yaseMelika, ibaluleke ngantoni kuthi? Kodwa ezonyango yinto yehlabathi liphela. Inkqubela phambili okanye ukulungiswa kwesayensi okwenzeka kwenye indawo yehlabathi kuchaphazela ihlabathi liphela.
- Unyango Olufanelekileyo: Oku kuqinisekisa ilungelo lesigulana, naphi na emhlabeni nakweliphi na ilizwe, lokufumana uxilongo oluchanekileyo noluchanekileyo.
- Ukulungisa iimpazamo kwezonyango: Lo ngumzekelo obalaseleyo wendlela amayeza asebenza ngayo rhoqo ekuzihlaziyeni nasekulungiseni iimpazamo zawo.
- Ukumamela ilizwi lesigulana: Ilizwi lesigulana nalo libe negalelo elikhulu ekwenzeni olu tshintsho. Oku kubonisa indlela ekubaluleke ngayo ukumamela izimvo zezigulana, endaweni yokuba uluntu lwezonyango lodwa luthathe izigqibo.
Kakade ke, ukutshintsha le milinganiselo akuyi kususa konke ukungalingani kwezempilo ngobusuku obunye. Zininzi izinto zentlalo nezoqoqosho ezinegalelo kuzo. Kodwa eli linyathelo elinamandla nelibalulekileyo kuloo ndlela.
Ukuba wena okanye umntu omaziyo unesifo sezintso, thetha ngokukhululekileyo nogqirha wakho malunga novavanyo lwakho lwezonyango kunye nonyango. Babuze nge-eGFR yakho, ithetha ukuthini, kunye neendlela zonyango ezilungileyo kuwe.
Umyalezo Wokuya Ekhaya
- I-eGFR (i-estimated Glomerular Filtration Rate) yindlela ebalulekileyo yokubala elinganisa ukusebenza kwezintso.
- I-eGFR equation eyayisetyenziswa ngaphambili yayibandakanya 'uhlanga' (ingakumbi kubantu abamnyama) kwi-equation, nto leyo eyabangela ukuphathwa kakubi kunye nokulibaziseka kwezigulane.
- Ngokuqonda ukuba 'uhlanga' aluyonto yebhayoloji, kodwa yingcamango yentlalo, ngoku kuye kwaveliswa ii-equations ezintsha nezilungileyo ze-eGFR ezingabandakanyi 'uhlanga'.
- Olu tshintsho linyathelo elibalulekileyo ekunciphiseni ukungalingani kwezempilo kunye nokubonelela ngonyango olufanelekileyo kubo bonke abaguli.
- Ukuba unenkxalabo malunga neerekhodi zakho zonyango kunye nonyango, kubaluleke kakhulu ukuthetha ngayo ngokukhululekileyo nangokucacileyo nogqirha wakho.
Isifo sezintso, i-eGFR, i-creatinine, uvavanyo lwezintso, ukungalingani kwezempilo, amayeza, isifo sezintso
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