Masifunde ngeyeza iFluorouracil (5-FU), eliza kukunceda ekulweni nomhlaza!

Kuqhelekile ukuba uzive uthwele umthwalo onzima xa usiva ukuba wena okanye umntu osondeleyo kuwe unomhlaza. Kwangaxeshanye, xa oogqirha bethetha ngonyango lwale meko, ingakumbi xa besiva amagama anjenge "chemotherapy", kunokuba nzima ngakumbi. Kodwa xa unolwazi olufanelekileyo ngezi zinto, uya kufumana amandla amaninzi okuqhubeka nolu hambo. Namhlanje siza kuthetha ngeyeza elisetyenziswa rhoqo elinceda ukulwa neeseli zomhlaza. YiFluorouracil leyo, abanye bayibiza ngokuba yi -5-FU .

Luhlobo luni lweyeza iFluorouracil (5-FU)?

Ngamafutshane, i-fluorouracil liyeza elilawula ukukhula kweeseli zomhlaza, oko kukuthi, liyazicothisa . Njengokulawula ukhula, inceda ekuthinteleni ukusasazeka kweeseli zomhlaza. Luhlobo lwe-chemotherapy. Oogqirha basebenzisa eli yeza ukunyanga iintlobo ezahlukeneyo zomhlaza. Nazi imizekelo embalwa:

• Umhlaza webele
• Umhlaza weColon okanye weRectal
• Umhlaza wePancreatic
• Umhlaza wesisu

Eli yeza ngamanye amaxesha lingafumaneka phantsi kwamanye amagama, umzekelo `iAdrucil`. Kwakhona, ugqirha wakho angalisebenzisa eli yeza ngezinye iinjongo kuxhomekeke kwimeko yakho. Ngoko ke ukuba unemibuzo, kungcono ukubuza ugqirha wakho okanye ikhemisti.

Zeziphi izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza?

Eli linqaku elibaluleke kakhulu. Ngaphambi kokuba uqale ukusebenzisa eli yeza, kubalulekile ukunika ugqirha wakho inkcazo epheleleyo ngemeko yakho yempilo. Nokuba yinto encinci kufuneka uyixelelwe ngaphandle kokuyifihla. Kuba, ngokusekelwe kolo lwazi, izinto ezinje ngokuba eli yeza lifanelekile na kuwe kunye nokuba lingakanani na eliza kunikelwa ziyagqitywa. Ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba uxelela ugqirha wakho:

• Ukuba kukho isifo okanye ingxaki egazini (Iingxaki zegazi).
• Ukunqongophala kwe-Dihydropyrimidine Dehydrogenase (DPD) yimeko yemfuza. Abantu abangonelisiyo kule enzyme banokuba nobunzima bokunyamezela ichiza i -fluorouracil , elinokubangela iziphumo ebezingalindelekanga ezibi kakhulu. Yiyo loo nto kubalulekile ukuthetha ngayo.
• Naluphi na usulelo olukhoyo ngoku , ingakumbi usulelo olubangelwa ziintsholongwane olufana ne -chickenpox kunye ne-herpes`(Usulelo lwentsholongwane olufana ne-chickenpox, izilonda zomkhuhlane , okanye i-herpes)`.
• Isifo sezintso .
• Isifo sesibindi.
• Ukuba awondlekanga , oko kukuthi, ukuba awufumani kutya namanzi aneleyo, kwaye imeko yakho yesondlo iphantsi.
• Ukuba usandul' ukufumana unyango lwe-radiation okanye ulufumana ngoku .
• Ukuba unempendulo engaqhelekanga okanye ye-allergy kwi- fluorouracil , amanye amayeza e-chemotherapy, naluphi na olunye unyango, ukutya, iidayi, okanye izithinteli .
• Ukuba ukhulelwe okanye uzama ukukhulelwa , oku kubaluleke kakhulu.
• Ukuba ungumama oncancisayo .

Hayi nje kuphela ezi zinto, kodwa xelela ugqirha wakho ngazo naziphi na iingxaki zempilo onazo.

Ndingakunika njani eli yeza?

I-Fluorouracil (5-FU) idla ngokunikwa njengenaliti emthanjeni okanye njenge-infusion emthanjeni, efana ne-saline . Oku akuyonto onokuyenza ekhaya. Olu nyango lunikwa esibhedlele okanye eklinikhi yingcali yezempilo eqeqeshwe ngokukodwa ukwenza oku. Kufuneka kuthathwe inyameko ekhethekileyo xa kunikwa abantwana abancinci eli yeza. Ukuba umntwana wakho uza kunikwa eli yeza, thetha nogqirha wezingane ngalo.

Kuthekani ukuba ndisela amayeza amaninzi kakhulu? Okanye ukuba ndiphoswa yidosi?

Ukuba ucinga ukuba usele amayeza amaninzi kakhulu, fowunela iziko lolawulo lwetyhefu okanye igumbi longxamiseko ngoko nangoko . Kubaluleke kakhulu ukusela amayeza akho njengoko ugqirha wakho ekuyalele. Ukuba ngenxa yaso nasiphi na isizathu awukwazi ukuza kunyango lwakho ngosuku olucwangcisiweyo, fowunela ugqirha wakho okanye umboneleli wezempilo ngoko nangoko uze ubazise .

Ziziphi ezinye iindlela ezinokwenzeka xa usebenzisana nale mithi?

Kukho amayeza athile anokubangela iingxaki xa esetyenziswa nge -fluorouracil . Ngoko ke, kufuneka uxelele ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka iivithamini, amayeza esintu, kunye nezongezo zokutya. Ngokukodwa, akufanele usebenzise i-fluorouracil kunye namayeza alandelayo :

• Iivayirasi eziphilayo : Ngenxa yokuba amasosha omzimba wakho anokuba buthathaka xa usela eli yeza, ukufumana izivayirasi eziphilayo kunokubangela usulelo.

Kwakhona, kukho amanye amayeza anokusebenzisana ne -fluorouracil . Umzekelo:

• Amayeza athintela okanye anyanga ukujiya kwegazi (umz. i-warfarin, i-enoxaparin, i-dalteparin).

Olu luhlu aluphelelanga. Ngoko ke, xelela ugqirha wakho ngazo zonke iziyobisi ozisebenzisayo, icuba olitshayayo, utywala obuselayo, kunye neziyobisi ezingekho mthethweni ozisebenzisayo . Ezinye izinto zinokuchaphazela amayeza akho.

Zeziphi izinto ekufuneka uzilumkele xa usebenzisa amayeza?

Ufanele ukhathalele umzimba wakho kakuhle ngelixa usebenzisa unyango lwe-fluorouracil .

• Bona ugqirha wakho rhoqo uze ujonge imeko yakho .
• Eli yeza linokukwenza uzive ungakhululekanga kwaye ubuhlungu ngaphezu kwesiqhelo . Oku kuqhelekile. Oku kungenxa yokuba amayeza e-chemotherapy anokuchaphazela kungekuphela nje iiseli zomhlaza, kodwa neeseli ezisempilweni. Nangona kunjalo, qhubeka nonyango olunikiweyo de ugqirha wakho akuxelele ukuba uyeke .
• Ukuba ufumana naziphi na iziphumo ebezingalindelekanga, xelela ugqirha wakho . Ngamanye amaxesha amanye amayeza anokumiselwa ukulawula iziphumo ebezingalindelekanga. Landela imiyalelo yokusebenzisa amayeza njengoko kuyalelwe.
• Ukuba unomkhuhlane, ukubanda, umphimbo obuhlungu, okanye ezinye iimpawu zomkhuhlane , xelela ugqirha wakho okanye umboneleli wezempilo ngokukhawuleza . Musa ukuthatha naluphi na unyango olufuna ukulisebenzisa. Olu nyango lunokunciphisa amandla omzimba wakho okulwa nokugula. Ngoko ke, zama ukuhlala kude nabantu abagulayo kangangoko unako.
• Eli yeza linokukwandisa umngcipheko wakho wokopha okanye ukukrweleka . Xelela ugqirha wakho ukuba ubona ukopha okungaqhelekanga (umz. ukopha empumlweni, ukopha kweentsini, igazi elisendle lakho).
• Lumka kakhulu xa uhlamba amazinyo, ufaka i-floss, kwaye usebenzisa i-toothpick . Oku kunokubangela ukuba iintsini zakho zenzakale, zosuleleke, okanye zophe igazi. Ukuba uza kufumana naluphi na unyango lwamazinyo, xelela ugqirha wakho wamazinyo ukuba usela eli yeza.
• Musa ukuthatha amayeza okudambisa iintlungu anjenge -aspirin, i-paracetamol, i-ibuprofen, i-naproxen, kunye ne-ketoprofen ngaphandle kwengcebiso kagqirha wakho. La mayeza angayithomalalisa iimpawu ezifana nomkhuhlane.
• Musa ukukhulelwa ngelixa usela eli yeza . Ukuba umfazi okhulelweyo ufumana eli yeza, linokubangela ingozi enkulu kusana olungekazalwa. Ukuba uzama ukukhulelwa okanye ucinga ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko. Buza ugqirha wakho okanye ikhemisti ngolwazi oluthe kratya. Musa ukuncancisa ibele ngelixa usela eli yeza .
• Amadoda nawo kufuneka azi ngale nto . Ukuba uzama ukuba nomntwana, xelela ugqirha wakho ngayo, kuba eli yeza linokunciphisa inani lamadlozi.
• Unesifo sorhudo (intlungu yesisu).Ukuba unesifo sohudo, musa ukusithatha wedwa ekhemesti. Ukuba isifo sohudo sihlala iintsuku ezingaphezu kwezimbini, sinzima kakhulu, okanye sinamanzi, xelela ugqirha wakho.
• Eli yeza linokwenza ulusu lwakho lube buthathaka kakhulu ekukhanyeni kwelanga . Ngoko ke, nciphisa ukuvezwa kwakho elangeni kangangoko unako. Ukuba uphuma phandle, nxiba impahla egquma umzimba wakho kakuhle, nxiba iiglasi zelanga, kwaye usebenzise i-sunscreen. Musa ukusebenzisa izibane zelanga okanye iibhedi/ii-booths zelanga.

Zeziphi iziphumo ebezingalindelekanga ekufuneka ndimxelele ugqirha ngazo ngoko nangoko?

Njengazo zonke amayeza, i-fluorouracil inokubangela iziphumo ebezingalindelekanga. Ezinye azibi kakhulu, kodwa kufuneka uxelele ugqirha wakho ukuba ufumana naziphi na kwezi ziphumo ebezingalindelekanga . Ezi ziquka:

• Iimpendulo ze-allergy : ukurhawuzelela kwesikhumba, ukurhawuzelela, ukurhawuzelela, ukudumba kobuso, imilebe, okanye ulwimi.
• Ukwehla kwenani legazi : Eli yeza linokubangela ukwehla kwenani leeseli ezimhlophe zegazi (iiseli ezilwa nezifo), iiseli ezibomvu zegazi (iiseli ezithwala ioksijini), kunye neeplatelets (iiseli ezinceda ukujiya kwegazi). Oku kunokunyusa umngcipheko wakho wosulelo kunye nokopha .
• Iimpawu zosulelo : umkhuhlane okanye ukubanda, ukukhohlela, umphimbo obuhlungu, iintlungu okanye ubunzima bokuchama.
• Iimpawu zeeplatelets ezisezantsi okanye ukopha : ukukrweleka kwiindawo emzimbeni, amachaphaza amancinci abomvu eluswini (njengokuhlatywa yipini), umnyama, indle ethambileyo, igazi kumchamo.
• Iimpawu zeeseli ezibomvu zegazi ezisezantsi : ukuziva udiniwe ngendlela engaqhelekanga, ukuziva utyhafile xa umi, ukuziva unesizungu.
• Ubunzima bokuphefumla .
• Utshintsho embonweni (umz. ukubona okufipheleyo).
• Iintlungu zesifuba .
• Izilonda zomlomo (ngaphakathi emlonyeni, emilebeni).
• Isicaphucaphu nokuhlanza (okuqhelekileyo okanye okuqatha).
• Intlungu, ukudumba, kunye nokubomvu kwindawo efakwe kuyo inaliti .
• Intlungu, ukuba ndindisholo, okanye ukuziva uxinezelekile ezandleni okanye ezinyaweni .
• Ububomvu, ukudumba, okanye ubuhlungu bezandla okanye iintende zeenyawo (ekwabizwa ngokuba yi-'Hand-Foot Syndrome').
• Intlungu yesisu (eqatha).
• Ukopha okungaqhelekanga .

Ukuba ufumana naziphi na kwezi mpawu, musa ukuchitha ixesha kwaye yazisa ugqirha wakho okanye isibhedlele apho unyangwa khona ngoko nangoko .

Zeziphi iziphumo ebezingalindelekanga ezidla ngokungabalulekanga ngokwaneleyo ukuba zingaxelelwa ugqirha , kodwa ekufuneka zixelwe ukuba ziyaqhubeka okanye ziyakhathaza?

Kukho iziphumo ebezingalindelekanga, azibi nkulu kangako, kodwa ukuba ziyaqhubeka okanye ziyakukhathaza, kungcono uxelele ugqirha wakho.

• Utshintsho kwiminwe okanye ezinzwaneni (umz., ukutshintsha kombala, ukwaphuka lula).
• Urhudo (alubi kakhulu, luyaphela emva kweentsuku ezimbalwa).
• Ulusu olomileyo okanye olurhawuzelelayo .
• Ukulahlekelwa ziinwele . Oku kwenzeka kubantu abaninzi, kodwa iinwele ziyakhula kwakhona emva kokuba unyango luphelile.
• Intloko ebuhlungu .
• Ukutya akunancasa .
• Amehlo anovelwano elangeni .
• Ukuphazamiseka kancinci kwesisu, njengokungagaywa kakuhle kokutya .
• Iinyembezi ezingaqhelekanga ziphuma emehlweni .

Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona enye into engaqhelekanga, thetha nogqirha wakho ngayo.

Uligcina phi eli yeza?

Eli asiloyeza onokuligcina ekhaya. I-Fluorouracil (5-FU) inikwa esibhedlele okanye ekliniki, ngoko ke akufuneki ukhathazeke ngokuyigcina.

Okokugqibela, khumbula (Umyalezo Wokuya Ekhaya)

Eli nqaku lishwankathelo nje leyeza lokulwa nomhlaza i-fluorouracil (5-FU). Siyathemba ukuba oku kuya kukunika umbono malunga neli yeza. Nangona kunjalo, alithathi indawo yokuthetha nogqirha wakho, usokhemesti, okanye omnye umboneleli wezempilo .

Ukuba unemibuzo malunga nale mithi, indlela esebenza ngayo, iziphumo ebezingalindelekanga, okanye nantoni na enye, ungathandabuzi ukubuza iqela lakho lezonyango . Balapha ukukunceda.

Unyango lomhlaza lunokuba luhambo olunzima. Kodwa ngolwazi olufanelekileyo, ulwalathiso oluvela kugqirha wakho, kunye nenkxaso evela kusapho lwakho, ungajongana nalo mceli mngeni. Khumbula, awuwedwa .

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I- Fluorouracil, i-5-FU, umhlaza, i-chemotherapy, amayeza omhlaza, iziphumo ebezingalindelekanga, unyango lomhlaza