Funda ngeNeurosyphilis, ingxaki yesyphilis echaphazela ingqondo yakho kunye nenkqubo yemithambo-luvo!

Ngaba wakha wazibuza ukuba ezinye izifo zingaba yingozi kangakanani ukuba azinyangwa ngokufanelekileyo? Ngamanye amaxesha, kwanosulelo oludluliselwa ngesondo (STI) esingalunaki kakhulu, ukuba alunyangwa ngexesha, lunokubangela iimeko ezinzima ezinokuchaphazela ubomi bakho. Namhlanje siza kuthetha nge -neurosyphilis , ingxaki eyingozi enokwenzeka ukuba isifo esidluliselwa ngesondo esibizwa ngokuba yi-syphilis asinyangwa ngokufanelekileyo. Le yinto echaphazela ingqondo yethu kunye nomqolo, oko kukuthi, inkqubo yemithambo-luvo ephakathi.

Yintoni i-neurosyphilis? Inxulumene njani ne-syphilis?

Ngamafutshane, i-neurosyphilis yingxaki enkulu, enokuba yingozi kubomi ye-syphilis. Njengoko usazi, i-syphilis sisifo esidluliselwa ngokwabelana ngesondo. I-Syphilis ibangelwa yintsholongwane ebizwa ngokuba yiTreponema pallidum. Ngoko ke, i-neurosyphilis yenzeka xa le ntsholongwane ingena engqondweni yakho kunye/okanye kwi-spinal cord . Kodwa kubalulekile ukukhumbula ukuba ayinguye wonke umntu ofumana i-syphilis oza kuba ne-neurosyphilis. I-Neurosyphilis kunye ne-syphilis ziimeko ezimbini ezinxulumeneyo, kodwa zahlukile. I-Neurosyphilis ichaphazela ngokuthe ngqo inkqubo yakho ye-nervous system (CNS), eyingqondo yakho kunye ne-spinal cord. Ke ngoko, iimpawu ezibonakalayo zinxulumene nenkqubo ye-nervous system. Ekubeni i-syphilis sisifo esidluliselwa ngokwabelana ngesondo, iimpawu zayo zahlukile.

Okubaluleke kakhulu, ukuba ayinyangwa, i-neurosyphilis inokukhokelela ekukhubazekeni okungapheliyo, kwi-dementia , kwanasekufeni . Ke ngoko, kubalulekile ukufuna uncedo lwezonyango ngokukhawuleza nje ukuba ubona naziphi na iimpawu ze-syphilis okanye i-neurosyphilis.

Ziziphi iintlobo eziphambili ze-neurosyphilis?

Oogqirha bahlula i-neurosyphilis kwiintlobo ezintlanu eziphambili. Ezi zahlulwe zibe ngamaqela amabini: i-neurosyphilis yasekuqaleni kunye ne-neurosyphilis yasemva kwexesha .

I-Neurosyphilis yasekuqaleni

Ezi zezo zikolu didi:

• I-Asymptomatic Neurosyphilis (ANS): Le yimeko apho kungekho zimpawu zemithambo-luvo . Le meko inokwenzeka ngaphambi kokuba kuvele iimpawu ze-syphilis. Oogqirha bafumanisa oku ngokufumanisa ulwelo lwe-cerebrospinal (CSF)Kuphela xa kukho ubungqina bosulelo lwe-syphilis emva kovavanyo, kodwa isigulane asinazo iimpawu. Ukuba une-syphilis kwaye awunyangwa, le meko ye-'ANS' inokukhula kwiiveki ezimbalwa zokuqala ukuya kwiminyaka eliqela emva kosulelo .

• I-Meningeal Neurosyphilis: Kulapho iibhaktheriya ze-syphilis zisulela i-meninges yakho, ii-membranes ezintathu ezigubungela kwaye zikhusela ingqondo yakho kunye nomqolo. Cinga ngayo njengesigqubuthelo esikhuselayo esijikeleze ingqondo yakho esidumbayo . Kulapho ke iimpawu ezifana nentloko ebuhlungu , isicaphucaphu , kunye nokuhlanza ziqala ukubonakala. Ukuba i-syphilis ayinyangwa, inokukhula kwiinyanga ukuya kwiminyaka emva kosulelo.

• I-Meningovascular Neurosyphilis: Kule meko, iibhaktheriya ze-syphilis zibangela ukudumba kweendonga zemithambo yegazi (endarteritis) kwi-meninges. Oku kunokukhokelela ekuqhekekeni kwegazi (thrombosis), okuthintela imithambo yegazi kwaye kunciphise ukuhamba kwegazi ukuya kwizicubu zobuchopho. Oku kunokukhokelela kwiingxaki ezahlukeneyo, ezifana ne -stroke . Ukuba ayinyangwa, oku kunokuvela nakwiinyanga ukuya kwiminyaka emva kosulelo.

I-Neurosyphilis yasemva kwexesha

Ezi zezo zikolu didi:

• I-General Paresis: Oku kubangelwa kukutshatyalaliswa kancinci kancinci kwezicubu zobuchopho ngenxa yokudumba kwexesha elide kwe-meninges (meningoencephalitis). Oku kubangela iimpawu ezahlukeneyo zengqondo kunye neemeko. Iimpawu zokuqala ziquka ukutshintsha kweemvakalelo kunye notshintsho lobuntu . Ukuba i-syphilis ayinyangwa, inokwenzeka phakathi kweminyaka emi-3 ukuya kwengama-30 emva kosulelo lokuqala.

• I-Tabes Dorsalis: Olu lolona hlobo lubi kakhulu lwe-neurosyphilis. Lubandakanya ukutshatyalaliswa kwezicubu kwikholamu yangasemva kunye neengcambu zemithambo-luvo. Oku kunokubangela iimpawu ezininzi, kubandakanya ubunzima bokuhamba, iintlungu zemithambo-luvo, kunye nobunzima bokulawula ukuchama. Ukuba i-syphilis ayinyangwa, i-tabes dorsalis inokukhula phakathi kweminyaka emi-5 ukuya kwengama-50 emva kokosuleleka.

Ngubani onokuthi abe ne-neurosyphilis?

Nabani na osuleleke yi-syphilis unokuba ne-neurosyphilis, ingakumbi ukuba i-syphilis ayinyangwanga kangangeenyanga okanye iminyaka.Abantu ababelana ngesondo bengakhuselekanga basengozini enkulu yokufumana i-syphilis. I-Syphilis ixhaphake kakhulu kumadoda abelana ngesondo namadoda (MSM). Uphando lubonise ukuba abantu abane-HIV banokubonakalisa iimpawu ze-neurosyphilis ngokukhawuleza kunabantu abangenayo i-HIV. Isizathu esichanekileyo soku asaziwa, kodwa kucingelwa ukuba i-HIV inokwenza buthathaka inkqubo yomzimba yokuzikhusela.

Ixhaphake kangakanani le meko?

Kunzima kubaphandi ukutsho ukuba ixhaphake kangakanani na i-Neurosyphilis kuba ingxelo yeziganeko ayingqinelani. Kodwa kukho idatha yokuba ixhaphake kangakanani i-syphilis. Yenye yezona zifo zixhaphakileyo ngokwesondo. Uhlobo oluxhaphakileyo lwe-neurosyphilis yi-neurosyphilis engenazimpawu (ANS) . Ngenxa yokuqhubela phambili kwisayensi yezonyango ekuthinteleni, ekuxilongeni, nasekunyangeni i-syphilis, iintlobo ezinzima ezifana ne-general paresis kunye ne-tabes dorsalis ngoku azixhaphakanga kangako.

Zithini iimpawu zeNeurosyphilis?

Iimpawu ze-Neurosyphilis zichaphazela kakhulu inkqubo yakho yemithambo-luvo. Ezi zahlukile kwiimpawu ze-syphilis. Iimpawu ezichanekileyo ziyahluka ngokuxhomekeke kuhlobo lwe-neurosyphilis. Kwinqanaba lokuqala, elingenazimpawu, i-neurosyphilis ayinazo kwaphela iimpawu.

Iimpawu zeMeningeal Neurosyphilis:

• Intloko ebuhlungu
• Isicaphucaphu nokuhlanza
• Ukuqina kwentamo
• Uloyiko lokukhanya (photophobia)
• Ubunzima bokubona okanye ukuva
• Ukungasebenzi kakuhle kwemithambo-luvo yentloko

Iimpawu zeMeningovascular Neurosyphilis:

Ukongeza kwiimpawu ezifana ne-meningeal, oku kungabandakanya:

• I-Vertigo
• Istroke
• Ubuthathaka okanye ukuwohloka kwemisipha (`atrophy`), ingakumbi emilenzeni

Iimpawu zeParesis Jikelele:

Oogqirha bahlula ezi mpawu zibe ziindidi ezimbini: kwasekuqaleni nasemva kwexesha. Ezi zinokuvela kancinci kancinci okanye ngequbuliso. Iimpawu zokuqala:

• Utshintsho lweemvakalelo, njengokucaphuka
• Utshintsho kubuntu
• Utshintsho kwiindlela zokulala
• Ukulibala

Iimpawu kamva:

• Iimvakalelo zokungasebenzi kakuhle
• Ukulahleka kwenkumbulo
• Ukukhubazeka kokwenza izigqibo
• Ukudideka
• Iingcamango eziphosakeleyo
• Ukuxhuzula (ukuxhuzula)

Le meko inokubangela izifo zengqondo ezifana nezi:

• Uxinzelelo
• I-Delirium
• Ukuxakeka kakhulu kunye nokuphambana
Izifo zengqondo ezifana ne -schizophrenia (psychosis)

Iimpawu zeTabes Dorsalis:

• Ukulahlekelwa yibhalansi xa uhamba (ataxia)
• Intlungu yemithambo-luvo eqatha
• Ubunzima bokulawula umchamo
• Iimvakalelo ezingaqhelekanga ezifana nokutsha, ukungaziva mnandi (i-paresthesia)
• Utshintsho lombono
• Iingxaki zamehlo, ezifana nokungasebenzi kakuhle kwelensi (`i-Argyll Robertson pupils`) kunye ne-ocular palsies
• Ukulahlekelwa yibhalansi kunye nokusabela kwengqondo
• I-Neuropathic arthropathy / Ilungu leCharcot
• Ubunzima bokuhamba

Ngoko ke zithini iimpawu ze-syphilis?

Iimpawu zeSyphilis ziyahluka ngokuxhomekeke kwinqanaba losulelo. Kwinqanaba lokuqala: Kuvela isilonda esincinci, esingenantlungu (chancre) kwizitho zangasese. Kwinqanaba lesibini: Kuvela irhashalala epinki, enamaqhuqhuva, nerhabaxa eluswini. Ezi zihlala zifumaneka kwiintende zezandla kunye neenyawo. Zisenokuhamba neempawu ezifana nomkhuhlane:

• Ukudinwa
• Ifiva
• Umqala obuhkungu
• Intlungu yemisipha

Kubaluleke kakhulu ukufuna iingcebiso zonyango ngokukhawuleza nje ukuba uqaphela naziphi na ezi mpawu. Ukuba ufumanisa ukuba iqabane lakho lesondo line-syphilis, ngokuqinisekileyo kuya kufuneka uvavanyelwe usulelo oludluliselwa ngesondo (STI).

Yintoni ebangela i-neurosyphilis?

I-Neurosyphilis ibangelwa yintsholongwane ebizwa ngokuba yiTreponema pallidum . Ngokukodwa, le ntsholongwane ingena kwinkqubo yakho yemithambo-luvo (CNS) kwaye ibangela iimpawu ezinxulumene nenkqubo yemithambo-luvo. Le yintsholongwane efanayo ebangela i-syphilis. Le ntsholongwane inokungena emzimbeni wakho nge-anus yakho, i-vagina, i-penis, umlomo, okanye ngokuqhekeka kwesikhumba. I-Neurosyphilis inokwenzeka nakweyiphi na inqanaba le-syphilis. Uphando lubonisa ukuba uninzi lwabantu abane-syphilis banale ntsholongwane esulela inkqubo yabo yemithambo-luvo, rhoqo ngaphambi kokuba bavelise naziphi na iimpawu ze-syphilis. Nangona kunjalo, kwabanye abantu, olu sulelo lwenkqubo yemithambo-luvo lunokupheliswa ngokwalo ngaphandle kokubangela ukudumba okanye iimpawu zemithambo-luvo. Nangona kunjalo, i-syphilis ayinakunyangwa ngaphandle konyango lwe-antibiotic. Okukhona uhlala usosulelekile yi-syphilis ngaphandle konyango, kokukhona umngcipheko wakho wokuba ne-neurosyphilis eneempawu.

Ngaba i-neurosyphilis iyosulela?

I-Neurosyphilis ayisasazeki ngqo ukusuka komnye umntu ukuya komnye. Yingxaki ye-syphilis. Kodwa i-syphilis isasazekile. Isasazeka ngokunxibelelana ngesondo nomntu osulelekileyo. Isondo sangasese sangasese, sangasese somlomo, okanye somlomo esingakhuselekanga kwandisa umngcipheko wokuba ne-syphilis.

Indlela yokuxilonga ngokuchanekileyo esi sifo?

Oogqirha badla ngokuxilonga i-neurosyphilis ngokusekelwe kwiimpawu zakho kunye novavanyo lwe-cerebrospinal fluid (CSF).Ngokusekelwe kwiziphumo. `CSF` lulwelo olucacileyo olujikeleze umqolo wakho kunye nobuchopho. Ugqirha uza kukubuza ngeempawu zakho kunye nembali yezonyango. Uza kwenza uvavanyo lomzimba kunye novavanyo lwemithambo-luvo. Ukuba kukho i-syphilis okanye i-neurosyphilis erhanelwayo, kuya kufuneka uvavanyo olulandelayo:

• Uvavanyo lwegazi ukukhangela ubungqina bebhaktheriya ebangela i-syphilis.
• Uvavanyo olubizwa ngokuba yi-lumbar puncture (i-spinal tap) . Kolu vavanyo, ugqirha ufaka inaliti encinci kakhulu emqolo wakho ongezantsi aze athathe isampuli ye-CSF.
• Uhlalutyo lolwelo lwe-cerebrospinal luvavanyo oluhlola isampuli ye-CSF phantsi kwemakroskopu ukuze kubonwe ukuba kukho iintsholongwane kuyo.

IZiko loLawulo lweZifo lase-US (i-CDC) licebisa ukuba wonke umntu one-syphilis, nokuba akayazi imeko yakhe ye-HIV, kufuneka avavanyelwe i-HIV, nokuba sele efunyenwe engenayo i-HIV ngaphambili.

Indlela yokunyanga? (Unyango)

Eyona nto ibalulekileyo onokuyenza ukuze uyeke i-neurosyphilis kwaye uyithintele ukuba ingabi mbi kakhulu kukunyanga usulelo lwe-syphilis. Oogqirha basebenzisa amayeza okubulala iintsholongwane ukunyanga i-syphilis kunye nezinye izifo ezibangelwa yintsholongwane. Eyona antibiotic iqhelekileyo enikwayo yi -penicillin , nokuba inikwa njengenaliti ye-IV (efakwa ngaphakathi kwemithambo) okanye njengenaliti kwisihlunu. Enye i-antibiotic eqhelekileyo esetyenziselwa ukunyanga i-syphilis yi -ceftriaxone . Emva konyango, kuya kufuneka wenze uvavanyo lwegazi oluninzi ngamaxesha ahlukeneyo, njengakwiinyanga ezintathu nakwiinyanga ezintandathu, ukuqinisekisa ukuba usulelo luphelile ngokupheleleyo. Kuya kufuneka wenze i-lumbar puncture ukuze uvavanye i-CSF yakho rhoqo kwiinyanga ezintandathu ukuqinisekisa ukuba akukho sulelo kwinkqubo yemithambo-luvo ephakathi.

Ugqirha wakho uza kukuxelela okungakumbi ngezi mvavanyo zokulandelela. Musa ukoyika ukubuza imibuzo ngale nkqubo.

Ngaba umonakalo obangelwe yi-neurosyphilis ungabuyiselwa?

Unyango lwe-antibiotic lunokuthintela i-neurosyphilis ukuba ingabi mandundu. Nangona kunjalo, kusenokungenzeki ukuba kuguqulwe ngokupheleleyo umonakalo owenzekileyo kwinkqubo yemithambo-luvo. Abantu abane-neurosyphilis engenazimpawu okanye i-meningeal neurosyphilis badla ngokuchacha ukuba banyangwa ngokufanelekileyo. Nangona kunjalo, abantu abane-meningovascular neurosyphilis, i-general paresis, okanye i-tabes dorsalis banokufumana uphuculo oluthile kwiimpawu zabo emva konyango, kodwa basenokungachachi ngokupheleleyo.

Ungazikhusela njani kule meko? (Ukuthintela)

Eyona ndlela yokuthintela i-neurosyphilis kukuthintela ukuba i-syphilis ingakhuli.. Eyona ndlela isebenzayo yokuthintela i-syphilis kukuzikhwebula kwisondo. Ukuba ulala nomntu osebenza naye, unganciphisa umngcipheko wokuba ne-syphilis ngokusebenzisa iindlela ezikhuselekileyo ngalo lonke ixesha ulala nomntu. Kubalulekile ukusebenzisa ikhondom (yendoda okanye yebhinqa) ngokuchanekileyo ukunciphisa umngcipheko wosulelo. Kubalulekile nokufuna iingcebiso zonyango kunye nonyango ngokukhawuleza nje ukuba ubonakalise iimpawu ze-syphilis. Unyango lwasekuqaleni lunokuthintela i-neurosyphilis ekubeni ibe nzima ngakumbi.

Ithini i-prognosis ukuba unesifo se-neurosyphilis?

Imbonakalo ye-neurosyphilis ixhomekeke kuhlobo lwe-neurosyphilis onayo kunye nokuba ufumana unyango ngokukhawuleza kangakanani. Abantu abane-neurosyphilis engenazimpawu okanye i-meningeal neurosyphilis abafumana unyango olufanelekileyo badla ngokuchacha ngaphandle kweempawu okanye iingxaki ezingapheliyo ze-neurological. Abantu abane-meningovascular syphilis, i-general paresis, okanye i-tarsis dorsalis banamathuba amaninzi okuba neempawu okanye iingxaki ezingapheliyo ze-neurological. Nangona kunjalo, unyango lunokunceda ekunciphiseni iimpawu kunye nokuthintela i-neurosyphilis ukuba ibe mandundu. Ukuba i-syphilis ayinyangwa, i-tarsis dorsalis inokubulala.

Ngawaphi amaxesha afanelekileyo okubonana nogqirha?

Ukuba ugqirha ukuxilonga ukuba une-neurosyphilis, kuya kufuneka ugqibezele unyango olupheleleyo lwe-syphilis. Kuya kufuneka wenze iimvavanyo ezininzi zokulandelela ukuqinisekisa ukuba akukho zimpawu zebhaktheriya emzimbeni wakho. Kubaluleke kakhulu ukugcina la madinga. Ukuba uhlakulela iimpawu ze-neurological eziqhubekayo okanye iimeko ngenxa ye-neurosyphilis, kuya kufuneka ubone iqela lakho lezonyango rhoqo ukuze ufumane unyango lwezo meko zithile.

Ukuthetha nogqirha ngezifo ezidluliselwa ngesondo kunokuba yintloni. Nangona kunjalo, ukuba ukrokrela ukuba une-syphilis, kubaluleke kakhulu ukubona ugqirha ukuze ahlolwe kwaye anyangwe. Ukuba ayivavanywanga kwaye inyangwe kwangethuba, inokukhokelela kwiingxaki zempilo ezinde, ezifana ne-neurosyphilis. Thetha nogqirha wakho malunga nokuvavanywa rhoqo kwe-syphilis kunye nezinye izifo ezidluliselwa ngesondo (ii-STI). Oku kunokunciphisa umngcipheko weengxaki. Musa ukoyika ukubuza imibuzo. Bakho ukukunceda, ngaphandle kokugweba.

Umyalezo Wokuya Ekhaya

• I-Neurosyphilis yingxaki eyingozi ye-syphilis enganyangwanga. Ichaphazela ingqondo yakho kunye nomqolo.
• I-Syphilis sisifo esidluliselwa ngesondo esibangelwa yintsholongwane iTreponema pallidum .
• Kukho iintlobo ezahlukeneyo ze-neurosyphilis, ezinye zazo zinokwenzeka kwangethuba kwaye ezinye zingenzeka kamva. Iimpawu nazo ziyahluka ngokufanelekileyo.
• Ukuxilongwa kwangoko kunye nonyango lwe-syphilisI-Neurosyphilis inokuthintelwa.
• Iindlela zesondo ezikhuselekileyo kunye nokuhlolwa rhoqo ngugqirha kubaluleke kakhulu.
• Ukuba uneempawu ze-syphilis okanye i-neurosyphilis, ungabi nantloni kwaye funa ingcebiso kagqirha ngokukhawuleza. Unyango olukhawulezileyo lunokuthintela iingxaki ezinkulu.