Usenokuba unengxaki yokuxinezeleka kwengqondo okanye ukudakumba kule mihla. Ngeli xesha, ugqirha wakho usenokuba ukunike iyeza elibizwa ngokuba yiVilazodone (ekwaziwa ngegama lebhrendi elithi Viibryd). Eli likwaliyeza elisetyenziselwa ukunyanga ukudakumba. Kodwa linomahluko omncinci kwamanye amayeza. Ngoko ke namhlanje, masithethe ngezinto ezibalulekileyo ekufuneka uzazi ngale mithi yeVilazodone.
Zeziphi iimeko ezinyangwa yiVilazodone (Viibryd)?
Eli yeza, elibizwa ngokuba yiVilazodone, linikwa ikakhulu njengonyango lweMajor Depression Disorder (MDD) . Oku yinto esiyibiza ngokuba yi "depression".
Kwakhona, ngamanye amaxesha oogqirha banokukunika eli yeza kwezinye iimeko. Umzekelo:
- Iingxaki zokuxhalaba
- Ingxaki yoxinzelelo emva kwengozi (PTSD)
- Uxinzelelo lweBipolar
- Iintlungu ezingapheliyo
- Ubushushu obuvela xa umntu eyeka ukuya exesheni
Nangona iVilazodone ingavunywanga ngokusesikweni ukuba inyange ezi meko, ezinye izigulana ziye zafumana iziphumo ezilungileyo ngayo, ngoko oogqirha bayicebisa ukuba "ingasetyenziswanga," oko kuthetha ukuba ayivunywanga ngokusesikweni kwimeko leyo, ukuze kuzuze isigulana.
Eyona nto ibalulekileyo kukuba eli yeza livunyelwe abantu abadala kuphela . Alinikwa abantwana. Ngokwesiqhelo, oogqirha banika eli yeza kubantu abangakhange bafumane iziphumo eziphumelelayo besebenzisa elinye iyeza lokudakumba .
Eli yeza lisebenza njani emzimbeni?
Ukuze sikuqonde oku, kufuneka siqale sazi kancinci nge -serotonin engqondweni yethu. Ngamafutshane, i-serotonin yikhemikhali elawula izinto ezininzi engqondweni yethu, kuquka isimo sethu sengqondo, ulonwabo, kunye nokulala. Kukholelwa ukuba abantu abanesifo soxinzelelo banezinga eliphantsi le-serotonin.
Into eyenza iVilazodone yahluke kwezinye kukuba yonyusa amanqanaba e-serotonin ngeendlela ezimbini.
1. Ukusebenza njenge-SSRI:I-Vilazodone liyeza elikudidi lwamayeza abizwa ngokuba yi -Selective Serotonin Reuptake Inhibitors (SSRIs) . Emva kokuba i-serotonin ikhutshiwe, idla ngokufunxwa kwakhona kwiiseli zemithambo-luvo . Kodwa i-SSRI iyayithintela ekubeni ifunxwe kwakhona. Oku kuvumela i-serotonin ukuba ihlale engqondweni ixesha elide, nto leyo enceda ukuphucula imeko yethu yeemvakalelo.
2. Ukusebenza njenge-5-HT1A Partial Agonist: Eli yeza likwavuselela ii-receptors ezifumana imiyalezo ye-serotonin. Oku kwandisa ngakumbi umsebenzi we-serotonin.
Ngenxa yokuba inyusa amanqanaba e-serotonin engqondweni ngeendlela zombini , iVilazodone inokuba luncedo ngakumbi kwabanye abantu.
Isetyenziswa njani iVilazodone (Viibryd)?
Eli yeza liza ngendlela yepilisi. Eyona nto ibalulekileyo kukuba eli pilisi lifanele lisetyenziswe rhoqo xa kutyiwa. Lisele neglasi yamanzi emva kokutya.
Ugqirha wakho uhlala eqala nge-10mg (ii-milligram) ngosuku. Emva kweentsuku ezisi-7 zokuyisebenzisa, baya kuyinyusa idosi iye kwi-20mg ukuba kuyimfuneko. Abanye abantu banokufuna ukwandisa idosi iye kwi-40mg. Nangona kunjalo, kufuneka kubekho ubuncinane isithuba seentsuku ezisi-7 phakathi kwedosi nganye. Konke oku kuya kwenzeka ngokwemiyalelo kagqirha wakho.
Kuthatha ixesha elingakanani ukufumana iziphumo?
Lo ngumbuzo abantu abaninzi abawubuzayo. Emva kweveki okanye ezimbini uqalile ukusebenzisa amayeza, uya kuqaphela ukuba ukutya kwakho, ukulala, kunye namanqanaba akho amandla aya kuphucuka kancinci. Oku kuthetha ukuba amayeza aqala ukusebenza. Nangona kunjalo, kungathatha malunga neeveki ezi-6 ukuya kwezi-8 ukuba ukudakumba kuphele ngokupheleleyo kwaye umdla wakho emsebenzini ubuye. Ngoko ke nceda ube nomonde kwaye usebenzise amayeza.
Kubaluleke kakhulu: Eli yeza kufuneka lisetyenziswe ngononophelo, njengoko kufanele limiswe. Ungaze uyeke ukulithatha ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela iziphumo ebezingalindelekanga ezimbi (i-discontinuation syndrome) ezifana nesicaphucaphu, ukuhlanza, ixhala, intloko ebuhlungu, iimvakalelo zokurhawuzelela, kunye nokubila. Ukuba uyeka ukulithatha eli yeza, kufuneka unciphise umthamo kancinci kancinci. Ugqirha wakho uza kukuchazela indlela yokwenza oku.
Zithini iziphumo ebezingalindelekanga zale yeza?
Njengezinye izidambisi-ntlungu, iVilazodone inokubangela iziphumo ebezingalindelekanga. Ezinye ziqhelekile, kodwa ezinye zinokuba yingozi. Izinto ezifana nokucaphuka kunye nokuphazamiseka kwesisu ziya kuphela njengoko umzimba wakho uqhela amayeza. Kodwa kukho iimpawu ezithile ekufuneka uxelele ugqirha wakho ngazo.
| Uhlobo lwesiphumo esibi | Iimpawu ezinokwenzeka |
|---|---|
| Iziphumo Eziqhelekileyo Ezingalindelekanga | |
| Iingxaki zenkqubo yokugaya ukutya | Urhudo (ukudumba), isicaphucaphu, ukuhlanza. |
| Iingxaki zokulala | Ukungalali kakuhle okanye ukuphazamiseka kokulala. |
| Iziphumo Ezingaqhelekanga Eziqhelekileyo | |
| Iingxaki zesondo | Ukuncipha komnqweno wesondo, ubunzima bokufumana okanye ukugcina ukuma, ukucotha kokuphuma kwesisu. (Nangona kunjalo, eli yeza lineziphumo ebezingalindelekanga zesondo ezimbalwa kunezinye ii-SSRI.) |
| Ukuphambana/Ukungakhathali | Ukuba unesifo sengqondo esibizwa ngokuba yi-bipolar disorder, unokufumana iimpawu ezifana nokuziva unamandla aphezulu, ukuziphatha ngokungakhathali, kunye nokuphuma kweengcinga ngokukhawuleza. |
| Iziphumo Ezimbi Ezifuna Unyango Olukhawulezileyo | |
| Isifo seSerotonin | I-serotonin egqithisileyo emzimbeni. Iimpawu ziquka ukushukuma, ukubona izinto ezingekhoyo, ukubila kakhulu, ukubetha kwentliziyo ngokukhawuleza, ukuqina kwemisipha, ukungcangcazela, ukuhlanza, kunye norhudo. Le yimeko engxamisekileyo. |
| Iingcinga zokuzibulala | Iingcinga zokuzibulala okanye zokuzilimaza, ingakumbi xa uqala ukuthatha iyeza okanye xa idosi itshintshiwe. Ukuba unezi ngcinga, xelela ugqirha wakho okanye umntu osondeleyo kuwe ngokukhawuleza. |
| Ukuxhuzula | Umngcipheko uphezulu ukuba ukhe waxhuzula ngaphambili okanye unesifo sokuxhuzula. |
| Ukopha okungaqhelekanga | Umngcipheko uphezulu xa usetyenziswa kunye neepilisi zokudambisa iintlungu ezifana ne-aspirin, ii-NSAID (umz., i-Ibuprofen, i-Diclofenac), okanye ezinye izinto zokunciphisa igazi. |
| I-Glaucoma eValwayo yi-Angle | Iintlungu zamehlo, ukubona izinto ezifipheleyo, ukubona izangqa ezinemibala zijikeleze izibane. |
| Ukuncipha kwe-sodium egazini (i-Hyponatremia) | Intloko ebuhlungu, iingxaki zenkumbulo, ukudideka, ukungazinzi xa uhamba. Kwiimeko ezinzima, ukulahlekelwa zingqondo kunye nokuxhuzula kunokwenzeka. |
Izilumkiso ekufuneka uziqaphele xa usebenzisa iVilazodone (Viibryd)
Ngaphambi kokuba uqale eli yeza, qiniseka ukuba uxelela ugqirha wakho ngezi zinto.
- Amanye amayeza owasebenzisayo: Xelela ugqirha wakho malunga nawo nawaphi na amayeza, iivithamini, okanye amayeza esintu owasebenzisayo, ingakumbi i-aspirin, ii-NSAID (ezifana ne-ibuprofen), kunye nezinye izinto ezinciphisa igazi.
- Ukukhulelwa nokuncancisa: Qiniseka ukuba uxelela ugqirha wakho ukuba ukhulelwe, uceba ukukhulelwa, okanye uncancisa.
- Ezinye iimeko zempilo: Nceda usazise ukuba unesifo sengqondo esibizwa ngokuba yi-bipolar disorder, isifo sokuwa okanye isifo sokuxhuzula, isifo se-glaucoma, isifo sesibindi okanye sezintso.
- Ijusi yegrapefruit: Xelela ugqirha wakho ukuba usela ijusi yegrapefruit rhoqo, kuba oko kunokuchaphazela ukusebenza kakuhle kwale mayeza.
- Amayeza e-MAOI: Kungcono ungayisebenzisi iVilazodone ukuba uthatha enye i-antidepressant ebizwa ngokuba yi-Monoamine Oxidase Inhibitor (MAOI) okanye kutshanje uyekile ukuyisebenzisa. Oogqirha bacebisa ukuba ulinde ubuncinane iintsuku ezili-14 emva kokuyeka i-MAOI ngaphambi kokuba uqale eli yeza.
Umyalezo Wokuya Ekhaya
- I-Vilazodone (i-Viibryd) liyeza elinyanga isifo sokudakumba okukhulu (MDD) kwaye lonyusa amanqanaba e-serotonin engqondweni ngeendlela ezimbini.
- Eli yeza lifanele lisetyenziswe rhoqo xa kutyiwa .
- Kungathatha malunga neeveki ezi-6-8 ukuze uve iziphumo ezipheleleyo zeyeza, ngoko ke yiba nomonde kwaye uqhubeke ulisebenzisa.
- Musa ukuyeka ukuthatha amayeza ngequbuliso nangasiphi na isizathu ngaphandle kwengcebiso kagqirha wakho.
- Lumka ngemiphumo emibi efana ne-serotonin syndrome, iingcinga zokuzibulala, kunye nokuxhuzula. Ukuba ufumana naziphi na kwezi mpawu, bonana nogqirha ngokukhawuleza.
- Yazisa ugqirha wakho malunga nazo zonke ezinye iziyobisi ozisebenzisayo kunye nazo naziphi na ezinye iimeko zempilo onokuba nazo ngaphambi kokuba uqalise amayeza.
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