Ngaba unyangwa ngePolatuzumab Vedotin (Polivy)? Masithethe ngale nto ngokulula

Xa ugqirha wakho ekuxelela okanye umntu omthandayo ekuxelela ukuba une-lymphoma, kuyinto eqhelekileyo ukuba nomdla kwaye woyike kancinci malunga neendlela zonyango. Ingakumbi xa usiva ngeyeza elitsha, elikhethekileyo njengePolatuzumab Vedotin, kusenokwenzeka ukuba unemibuzo emininzi malunga nokuba yintoni, isebenza njani, kwaye ingaba kukho naziphi na iziphumo ebezingalindelekanga . Ngoko ke ungakhathazeki. Namhlanje, siza kuthetha nge-Polatuzumab Vedotin (edla ngokubizwa ngokuba yi-brand Polivy vaccine) ngamagama alula nacacileyo.

Yintoni iPolatuzumab Vedotin?

Ngamafutshane, olu lunyango oluthile olunikwa ukubulala iiseli zomhlaza. Silubiza ngokuba yiTargeted Therapy. Ngokungafaniyo nechemotherapy eqhelekileyo, eli yeza likrelekrele kakhulu. Lifana "ne-missile ekrelekrele." Eli yeza lenziwe ngamacandelo amabini: 1. I-antibody ye-monoclonal : Le yi-"navigator." Ihamba emzimbeni wonke, ifumane iiseli zomhlaza (ingakumbi uhlobo olubizwa ngokuba yi-'Diffuse Large B-cell Lymphoma`), kwaye izincamathele kwiproteni ethile kumphezulu wazo. 2. Iyeza le-chemotherapy: Le yibhombu "ekwi-missile." Emva kokuba i-antibody ye-monoclonal ifumene kwaye izincamathele kwiseli yomhlaza, eli yeza le-chemo liya ngqo kwiseli yomhlaza lize liyitshabalalise. Ngenxa yale ndlela, umonakalo kwiiseli eziphilileyo uncinci kune-chemotherapy eqhelekileyo. Yiyo loo nto ikhethekileyo ngale nto.

Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango

Ukuze ugqibe ekubeni olu nyango lukulungele na kwaye lukhuselekile, kubalulekile ukuba unyaniseke kwaye uxelele ugqirha wakho ngembali yakho yempilo. Qiniseka ukuba ubandakanya oku kulandelayo kwingxoxo yakho:

• Iintsholongwane ezikhoyo ngoku: Ukuba unentsholongwane efana ne -chickenpox , i-herpes, okanye nayiphi na enye imeko eyosulelayo.
• Isifo sesibindi : Ukuba unayo nayiphi na imeko enxulumene nesibindi.
• Iingxaki zegazi: Ukuba uvavanyo lwegazi lubonisa inani eliphantsi leeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, okanye iiplatelets.
• Ingxaki yemithambo-luvo: Ukuba unesithukuthezi, ukurhawuzelela, okanye ezinye iingxaki ezinxulumene nemithambo-luvo ezithweni zakho.
• Ii-Allergies : Ukuba une-allergy (i-allergy) kule yeza, naluphi na olunye unyango, ukutya, okanye idayi.
• Ukukhulelwa: Ukuba ukhulelwe, uzama ukukhulelwa, okanye ukrokrela ukuba ukhulelwe.
• Ukuncancisa : Ukuba ungumama oncancisa umntwana.

Linikwa njani eli yeza kwaye kuthekani ukuba idosi ayithathwanga?

Eli yeza linikwa njenge-infusion emthanjeni, njenge-saline. Linikwa esibhedlele okanye ekliniki, phantsi kweliso lengcali eqeqeshiweyo, njengogqirha okanye umongikazi. Ngoko ke akufuneki ulithathe uye nalo ekhaya okanye ulifake ngokwakho.

Ekubeni eli yeza linikwa phantsi kweliso labasebenzi bezonyango esibhedlele, amathuba okuba lisetyenziswe ngokugqithisileyo mancinci kakhulu. Ukuba ukrokrela oku, xelela ugqirha wakho okanye umongikazi wakho ngokukhawuleza.

Ukuba awukwazi ukuya esibhedlele ukuze ufumane unyango ngomhla omiselweyo, ungakhathazeki, fowunela ugqirha wakho ngokukhawuleza. Uza kukuxelela into omawuyenze emva koko.

Izinto ekufuneka uzazi ngexesha lonyango

Kubalulekile ukunikela ingqalelo engakumbi emzimbeni wakho ngeli xesha.

Ukuhlolwa rhoqo kwezonyango

Ngelixa usela eli yeza, ugqirha wakho uhlala eyalela uvavanyo lwegazi ukujonga inani leeseli zakho zegazi (iiseli ezibomvu, iiseli ezimhlophe, iiplatelets) kunye nokusebenza kwesibindi. Musa ukulibazisa olu vavanyo.

Ukhuseleko kwizifo

Eli yeza linokunciphisa kancinci amandla omzimba wakho okulwa nezifo (amandla okulwa nosulelo). Ngenxa yoko:

• Ziphephe iindawo ezinabantu abaninzi kangangoko unako.
• Zigcine kude nabantu abanezifo ezifana nomkhuhlane kunye nomkhuhlane .
• Ukuba ufumana iimpawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, okanye ukukhwehlela , musa ukuzinyanga kwaye utsalele ugqirha wakho umnxeba ngoko nangoko.

Ingozi yokopha

Eli yeza linokunciphisa inani leeplatelet ezinceda ekuqhekekeni kwegazi. Ngoko ke, ukuba ubona nayiphi na imivumbo engaqhelekanga, amabala amancinci abomvu phantsi kolusu, indle emnyama, okanye igazi kumchamo, xelela ugqirha wakho ngokukhawuleza.

Isilumkiso esibaluleke kakhulu: usulelo lobuchopho

Amaxesha amaninzi, abanye abaguli banokuba nosulelo olukhulu oluchaphazela ingqondo (Progressive Multifocal Leukoencephalopathy - PML). Le yimeko enzima kakhulu. Qaphela kakhulu ezi mpawu zilandelayo.

Funa uncedo lwezonyango ngokukhawuleza ukuba wena okanye umntu omkhathaleleyo ufumana naziphi na kwezi mpawu: * Ukutshintsha kombono * Ubunzima bokucinga, ukudideka * Ubunzima bokuthetha okanye ukuqonda oko kuthethwa ngabanye * Ubunzima bokuhamba, ukulahlekelwa kukulinganisela * Ubuthathaka kwelinye icala lomzimba

Ukukhulelwa kunye nokuchuma

Oku kubaluleke kakhulu.

• Abafazi: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa olu nyango kwaye kangangeenyanga ezi-3 emva kokuyeka unyango.
• Amadoda: Kuphephe ukuba nguyise womntwana ngelixa uthatha olu nyango kwaye emva kweenyanga ezi-5 emva kokuyeka unyango.
• Ukuncancisa: Kuphephe ukuncancisa ngexesha lonyango kwaye kangangeenyanga ezimbini emva kokuba uyekile.

Eli yeza linokulimaza kakhulu usana olungekazalwa. Linokuchaphazela nokuzala kwamadoda nabasetyhini. Ukuba uneenkxalabo malunga noku, thetha nogqirha wakho.

Zithini iziphumo ebezingalindelekanga ezinokubakho?

Njengalo naliphi na iyeza, eli yeza linokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Nazi iziphumo ebezingalindelekanga eziqhelekileyo.

Iziphumo ebezingalindelekanga zePolatuzumab Vedotin ekufuneka uzixele kugqirha wakho ngoko nangoko Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ukuba ziyaqhubeka okanye ziyakhathaza

Iimpendulo ze-allergy	Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kwemilebe/ulwimi/ubuso.
Iingxaki zemithambo-luvo	Intlungu, ukuba ndindisholo, okanye ukurhawuzelela ezandleni nasezinyaweni (i-Peripheral Neuropathy).
Iimpawu zosulelo	Umkhuhlane, ukubanda, umphimbo obuhlungu, ukukhwehlela, usulelo lomchamo.
Iimpawu zokulimala kwesibindi	Umchamo otyheli obumnyama, ukutyheli kwamehlo/ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, isicaphucaphu.
Iimpawu zokubala igazi eliphantsi	Ukuziva udiniwe ngaphezu kwesiqhelo, ubomvu, unengxaki yokuphefumla, okanye ukrwempa okanye ukopha igazi lula.
Ezinye iimpawu ezinzulu	Ukugabha, urhudo, isiyezi, ubunzima bokubona, ukuthetha, okanye ukuhamba.
Ukunciphisa ukutya	Ukuncipha komnqweno wokutya.
Intlungu yamalungu	Intlungu yamalungu.
Ukuhla ukusinda	Ukunciphisa umzimba ngaphandle komzamo.

Umyalezo Wokuya Ekhaya

• I-Polatuzumab Vedotin lunyango oluthile, olujoliswe ngqo kumhlaza we-lymphoma. Isebenza ngokujolisa ngqo kwiiseli zomhlaza.
• Ngaphambi kokuba uqale unyango, kubalulekile ukuba uxelele ugqirha wakho ngalo lonke ulwazi lwakho lwezempilo kunye namayeza owasebenzisayo.
• Ukuba kukho iimpawu ezinzulu ezifana nomkhuhlane, ukopha, ukungaziva, okanye ubunzima bokuthetha/ukuhamba ngexesha lonyango, funa ingcebiso kagqirha ngoko nangoko.
• Landela imiyalelo kagqirha wakho ngokungqongqo malunga nokukhulelwa nokuncancisa.
• Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo okanye izinto ezikuxhalabisayo. Awuwedwa kweli dabi.