Ngaba i-asthma yakho kunzima ukuyilawula? Masifunde ngesitofu se-Xolair sokukhusela i-asthma enesifo esibi se-allergy.

Uninzi lwabantu abane-asthma banokukwazi ukulawula iimpawu zabo nge-inhaler yemihla ngemihla. Kodwa kwabanye abantu, le inhaler yodwa ayanelanga. Ingaba kunjalo nakuwe? Xa une-asthma enzima, kwaye amayeza akho aqhelekileyo engancedi, kunokuba ngumthwalo wokwenene, akunjalo? Kodwa ungakhathazeki. Kutshanje, kuye kwaziswa amayeza amatsha okunyanga ezi meko zinzima ze-asthma. La ayizizo ii-inhaler, kodwa zii-injection. Elinye lamayeza anjalo yi-Xolair.

Isebenza njani iXolair? Okokuqala, masiqonde kancinci ngesifo sesifuba.

Isifo sombefu, ngokufutshane, sisifo esinganyangekiyo esichaphazela imiphunga yethu. Sibangela ukudumba kweendlela zethu zomoya, iityhubhu ezithwala umoya ngemiphunga yethu. Izihlunu ezizijikelezileyo nazo ziyaqina. Oku kudumba nokuxinana kwenza iindlela zomoya zibe buthathaka kakhulu. Ngamanye amaxesha, zinokuvaleka yi-mucus.

Abantu abane-asthma bafumana iimpawu ezifana nokukhohlela, ukuphefumla nzima, ubunzima bokuphefumla, kunye nokuqina kwesifuba. Oku sikubiza ngokuba "luhlaselo lwe-asthma." Kukho izizathu ezahlukeneyo, okanye "izinto ezibangela uhlaselo," ezinokubangela uhlaselo.

Eyona nto ibangela isifo sesifuba kwabanye abantu yi -allergies . Inkqubo yomzimba yaba bantu isabela ngokugqithisileyo kwizinto ezithile. Ezi zinto sizibiza ngokuba yi-allergens . Kwaba bantu, xa ezi allergens zingena emzimbeni, ukuhlaselwa sisifo sesifuba kunokwenzeka.

Injongo ephambili yokunyanga isifo sesifuba kukunciphisa oku kudumba nokuxinana kwemiphunga. Oku kwenza kube lula ukuphefumla kwaye kunciphisa inani lokuhlaselwa sisifo sesifuba.

Iyeza iXolair liqulethe isithako esisebenzayo i-omalizumab . Lisebenza ngokuthintela into ebizwa ngokuba yi- Immunoglobulin E (IgE) emzimbeni wethu. Xa i-allergen endikhankanyileyo ngaphambili ingena emzimbeni, umzimba wethu uvelisa inani elikhulu le-IgE. Xa le IgE ivaliwe emzimbeni womntu one-asthma ye-allergy, impendulo yomzimba kwi-allergens kunye nokudumba kwemiphunga kuyancitshiswa.

Ngaba kukho umntu onesifo se-asthma onokuthi asebenzise eli yeza?

Hayi. Uninzi lwabantu abane-asthma lunokulawula iimpawu zabo ngokuphefumla rhoqo. Ngamanye amaxesha, imeko ilawulwa kakuhle ngamayeza omlomo.

I-Xolair inikwa kuphela abantu abane -asthma enzima abangakwaziyo ukulawula iimpawu zabo nangona besebenzisa idosi ephezulu ecetyiswayo ye-inhaler yabo. Kwakhona, ukuze usebenzise eli yeza, kufuneka ukuba uvavanyiwe ngugqirha kwaye uqinisekisiwe ukuba une-allergy kwi-aeroallergen engapheliyo, efana ne-dander yezilwanyana okanye iincukuthu zothuli.

Ufumanise njani ukuba eli yeza lisebenza kangakanani?

Izifundo ezininzi zeklinikhi zenziwe ukufumanisa ukuba iXolair ikhuselekile kwaye iyasebenza na. Ezi zenziwe kubantu abadala nakubantwana.

Bonke abathathi-nxaxheba kolu phononongo babenengxaki yokuphefumla nangona besebenzise idosi ephezulu yee-inhaler. Kwakhona kwaqinisekiswa ukuba bane-allergies, ezifana neencukuthu zothuli.

Ngamafutshane, nantsi indlela olu phando olwenziwe ngayo:

• Elinye iqela lanikwa ugonyo lweXolair. Elinye iqela lanikwa ugonyo olungeyonyani, i -placebo . Kodwa akukho mntu wayesazi ukuba bafumana ntoni.
• Wonke umntu waxelelwa ukuba aqhubeke nokusebenzisa ii-inhaler zakhe eziqhelekileyo.
• Emva kweenyanga ezimbalwa, idosi ye -corticosteroid inhaler yomntu wonke yancitshiswa kancinci kancinci.
• Emva koko bajonga ukuba abo bathathe iXolair bakhululeke ngakumbi na kunabo bathathe i-placebo.

Zithini iingenelo zophando?

Iingenelo ezimbini eziphambili zazibonakala ngokucacileyo.

1. Ukwehla kokuhlaselwa yi-asthma enzima: Iqela le-Xolair lalinomlinganiselo ophantsi kakhulu wokuhlaselwa yi-asthma enzima kuneqela le-placebo. Oku kwagcinwa nangona idosi ye-inhaler inciphisiwe.

2. Ubuchule bokunciphisa idosi ye-inhaler: Malunga nama-75% abantu abathathe i-Xolair bakwazile ukunciphisa idosi ye-inhaler ye-corticosteroid yabo yemihla ngemihla ngesiqingatha, xa kuthelekiswa nama-50% kuphela abo bathathe i-placebo.

Isetyenziswa njani i-Xolair vaccine?

I-Xolair yinaliti efakwa ngaphantsi kwesikhumba . Inikwa rhoqo emva kweeveki ezi-2 ukuya kwezi-4. Ugqirha wakho uya kugqiba ukuba kufuneka uyifumane kangaphi inaliti, ngokusekwe kubudala bakho, ubunzima, kunye nenqanaba le-IgE egazini lakho. Inaliti inganikwa ethangeni, esiswini, okanye ngasemva kwengalo engentla.

Into ebalulekileyo kukuba iidosi zokuqala ezimbalwa zesitofu zisoloko zinikwa esibhedlele okanye eklinikhi. Oku kukujonga ukuba ngaba unayo nayiphi na i-allergy reactions. Emva koko, ukuba uhlangabezana neemfuno ezithile, ugqirha wakho angakuvumela ukuba uzitofe ekhaya.

Zimbini iindlela zokufumana eli yeza. Elinye lisixhobo esifana nepeni esibizwa ngokuba yi-autoinjector . Oku kukuvumela ukuba ufake isitofu ngokulula ngaphandle kokusebenzisa isirinji okanye inaliti. Elinye lisirinji eliza nenaliti njengesiqhelo. Ukuba une-allergy kwi-latex, ungalibali ukuxelela ugqirha wakho ngayo. Kuba ezinye iisirinji zinokuba ne-latex.

Kuthatha ixesha elingakanani ukufumana isiqabu koku?

Ukuba isitofu se-Xolair sikulungele, kuya kufuneka uqale uzive ngcono kwiiveki ezimbalwa . Ekuhambeni kwexesha, uya kuba nohlaselo lwe-asthma oluncinci. Usenokukwazi nokunciphisa umthamo we-corticosteroid inhaler yakho.

Ukuba awuziva tshintsho emva kweenyanga ezimbalwa, yazisa ugqirha wakho ngaloo nto.

Iziphumo ebezingalindelekanga kunye nendlela yokuzilawula?

Abantu abasebenzisa iXolair banokuba namathuba amancinci okufumana usulelo lokuphefumla (umphimbo obuhlungu, umkhuhlane). Eyona ndlela ilungileyo yokuthintela oku kukuhlamba izandla zakho rhoqo, uhlale ucocekile, kwaye uhlale kude nabantu abagulayo. Kwaye ufumane inaliti yakho yonyaka yomkhuhlane.

Kunqabile kakhulu, abanye abantu banokuba ne-allergy enzima, ebizwa ngokuba yi-anaphylaxis , emva kokuthatha idosi yokuqala. Le yimeko enzima kakhulu. Yiyo loo nto iidosi zakho zokuqala ezimbalwa zihlala zinikwa esibhedlele. Apho, abasebenzi bezonyango abaqeqeshiweyo baya kukujonga baze balungele ukukunyanga ngoko nangoko ukuba kukho naziphi na iingxaki.

Ayizizo ezi kuphela, kodwa nezinye iziphumo ebezingalindelekanga zinokubakho. Ukuba uneempawu ezikukhathazayo, thetha nogqirha wakho.

Ngaba kukho iingxaki ngamanye amayeza?

Akukho nxibelelwano lubalulekileyo phakathi kweXolair kunye namanye amayeza. Nangona kunjalo, kubalulekile ukuxelela ugqirha wakho malunga nawo onke amayeza (abhalwe ngugqirha okanye athengiswa ngaphandle kwemvume kagqirha), iivithamini, amayeza emifuno, kunye nezongezo ozithathayo.