Ngaba ungumntu ohlala efumana i-allergies? Ngaba uqala ukurhawuzelelwa emva komoya othuliweyo, ngaba unamaqhuqhuva emva kokutya ukutya, okanye umane ukrwempa umzimba wakho ngamanye amaxesha? Namhlanje sithetha ngesosha elincinci kodwa elibaluleke kakhulu elingasemva kwazo zonke ezi zinto. Usenokuba ulibonile igama elithi 'Basophils' kwenye yeengxelo zakho zegazi, oko kukuthi, 'kwi-Full Blood Count'. Ngoko ke, zithini ezi basophils ? Kutheni imizimba yethu izifuna? Masithethe ngale nto ngendlela elula neqondakala lula.
Yintoni kanye kanye i-basophil?
Ngamafutshane, ii-basophils luhlobo lweeseli ezimhlophe zegazi (`iWhite Blood Cell` - WBC) egazini lethu. Khawuthelekelele ukuba imizimba yethu ifana nelizwe. Iiseli ezimhlophe zegazi zingamandla okhuselo kweli lizwe. Kukho amandla ahlukeneyo kweli gunya. Ngoko ke, kukho iintlobo ezintlanu zeeseli ezimhlophe zegazi. Ii-Basophils zezona zincinci kwiintlobo ezintlanu, oko kuthetha ukuba zingamandla anqabileyo kakhulu.
Ngaphakathi kwezi seli ze-basophil kukho iigranules ezincinci. Ezi granules zizaliswe yikhemikhali ebaluleke kakhulu ebizwa ngokuba yi-histamine. Le histamine ibangela amehlo arhawuzelelwayo, abomvu, kunye nempumlo evuzayo oyifumanayo xa une-allergy. Ii-Basophils zikwanceda ekukhuseleni imizimba yethu kwiintsholongwane kwaye ziphilisa amanxeba .
Uhlobo kunye neempawu ze-basophils
Ezi mpawu ze-basophils zibaluleke kakhulu koogqirha ukuze baxilonge izifo ezithile. Makhe sijonge ulwazi oluthile malunga nale joni lincinci.
| Uphawu | Inkcazo |
|---|---|
| Ubungakanani | Ezi zincinci kakhulu, zimalunga ne-5-10 micrometers (µm) ngobukhulu. |
| Inkangeleko kunye nombala | Xa kufakwa idayi ekhethekileyo (ibala likaWright-Giemsa), iigranule ezizaliswe yi-histamine ngaphakathi kwezi seli zibonakala zimfusa omnyama. Ezi zinokubonwa lula nge-microscope. |
| Iziko leeseli (iNucleus) | Umbindi weseli udla ngokumila njengonobumba u-'S'. |
| Ubude bobomi kunye nokuzalwa | Ii-Basophil ziveliswa kumongo wethambo ngaphakathi emathanjeni ethu. Xa sele zenziwe apho, ziphila iiyure ezingama-60 kuphela emva kokungena egazini. |
| Iimpawu zomphezulu | Iiproteni ezithile ezikhethekileyo ezikumphezulu wezi seli (ezifana ne-`CD-123`, `CD-193`) zinceda oogqirha ukuba baxilonge izifo ezifana nomhlaza othile wegazi (`Leukemia`). |
Yeyiphi inkonzo enikezelwa zii-basophils emizimbeni yethu?
Umsebenzi ophambili we-basophils kukukhupha i-histamine ebesithethe ngayo ngaphambili. Kodwa ukongeza, ezi seli zincinci zisebenza kakuhle emizimbeni yethu.
- Ukukhuselwa kwi -Allergens : Xa izinto ezifana nothuli kunye ne-pollen zingena emzimbeni, ziyazilwa nazo.
- Ukulwa neentsholongwane: Ezi zisebenza ngexesha losulelo lweentsholongwane ezifana neepinworms .
- Ukuphiliswa kwamanxeba : Kunceda kwinkqubo yokuphiliswa kwamanxeba.
- Ukuthintela ukuqhekeka kwegazi: Ezi seli zikhupha ikhemikhali ebizwa ngokuba yi-heparin, enceda ekunyibilikiseni ukuqhekeka kwegazi okungafunekiyo.
Ulwalamano phakathi kwe-allergies kunye ne-basophils
Khawucinge ngengcongconi iluma isandla sakho. Emva kwexesha elithile, indawo iba bomvu, idumbe, kwaye irhawuzelele kakhulu, akunjalo? Yiloo nto eyenziwa yi-histamine, ekhutshwa kwi-basophils.
Into eyenziwa yi-histamine kukwandisa ukuhamba kwegazi kwindawo leyo. Oku ke kuzisa igazi elingakumbi kwindawo leyo, "kulihlambe", kunceda ekukhupheni i-allergen. Oku kudumba kunye nokuvuvukala ngokwenene yinxalenye yenkqubo yokuphiliswa.
Xa i-allergen ingena emzimbeni womntu one-allergy, inkqubo yomzimba yokuzikhusela yenza uhlobo lwe-antibody ebizwa ngokuba yi-Immunoglobulin E (IgE). Le IgE iyahamba ize inamathele kwi-allergen. Emva koko ii-basophils ziza zihlasele le IgE-allergen complex, zikhuphe yonke i-histamine ezinayo ngaphakathi. Kulapho ufumana khona iimpawu ze-allergy.
- Impumlo egobhozayo, ethimla
- Amehlo abomvu, arhawuzelelayo
- Umphimbo orhawuzelelayo
- Ukurhawuzelela kwesikhumba, ukurhawuzelela
- Ubunzima bokuphefumla kwizigulane ze-asthma
Ujonga njani inqanaba le-basophil egazini lakho?
Ukuba ugqirha wakho ukuyalela ukuba wenze uvavanyo lwe-`Complete Blood Count (CBC)`, okanye njengoko silubiza njalo, 'count yegazi epheleleyo,' inani le-basophil nalo liya kudweliswa kuloo ngxelo. Oku kungafakwa kwingxelo ngeendlela ezimbini.
1. Njengepesenti (%): Yeyiphi ipesenti yeeseli ezimhlophe zegazi ezizii-basophils? Ngokwesiqhelo eli lixabiso lincinci kakhulu, malunga ne-0.5% - 1%.
2. Inani elipheleleyo: Inani langempela lee-basophils kwi-milliliter yegazi.
Eyona nto ibalulekileyo kukuthelekisa amaxabiso akho nekholamu ethi 'Normal Range' okanye 'Reference Range' kwingxelo yakho yelebhu, njengoko la maxabiso aqhelekileyo anokwahluka kancinci ngokuxhomekeke kumatshini osetyenziswa kwilebhu nganye.
| Inqanaba | Intsingiselo |
|---|---|
| Ubalo oluQhelekileyo | Phakathi kwe-0.5% - 2% yeeseli ezimhlophe zegazi. Ixabiso elipheleleyo lidla ngokuba phakathi kwe-0.01 x 10⁹/L ukuya kwi-0.08 x 10⁹/L. |
| Inqanaba elonyukileyo (iBasophilia) | Amanqanaba e-basophil aphezulu kunesiqhelo. |
| Inqanaba eliphantsi (iBasopenia) | Amanqanaba e-Basophil ehla ngaphantsi kwesiqhelo. |
Ngaba ukwanda kwe-basophils (basophilia) kuyingozi?
Ukunyuka kwamanqanaba e-basophil kwaziwa ngokwezonyango ngokuba yi-"Basophilia." Kunokubakho izizathu ezahlukeneyo zoku.
- Ii-Allergies: Ii-Allergies kwizinto ezinje ngokutya, amayeza, uthuli, njl.
- Izifo: Ezinye izifo ezifana ne-chickenpox kunye ne-influenza.
- Iingxaki ze-thyroid: I-hormone ye-thyroid ephantsi (`Hypothyroidism`).
- Izifo zesikhumba: Iimeko zesikhumba ezifana ne-eczema ezifana ne-atopic dermatitis.
- Izifo zegazi: Iimeko ezifana ne-polycythemia vera.
- Ezinye iimeko zomhlaza: Umhlaza wegazi ofana ne-chronic myeloid leukemia (CML).
Musa ukothuka lolu luhlu. Uninzi lwexesha, inani eliphezulu le-basophil linokubangelwa yinto elula njenge-allergy eqhelekileyo. Kodwa kufuneka uyishiyele ugqirha wakho ukuba afumanise unobangela ochanekileyo. Uza kwenza olunye uvavanyo ukuba kuyimfuneko ukuqinisekisa unobangela.
Yintoni i-basopenia?
Ukwehla kwamanqanaba e-basophil kubizwa ngokuba yi-``Basopenia``. Oku kunqabile kancinci kune-``Basophilia``. Oku kunokubangelwa zizizathu ezahlukeneyo.
- Ezinye izifo.
- Ukuveliswa kakhulu kwehomoni ye-thyroid (`Hyperthyroidism`).
- Ukusabela okuqatha nokunganyamezelaniyo kwangoko (`Anaphylaxis`).
- Ezinye izifo zenkqubo yomzimba yokuzikhusela, umzekelo `Systemic Lupus Erythematosus (SLE)`.
Ukuncipha kwe-basophils kunokuba nefuthe kwinkqubo yokuphiliswa kwamanxeba emzimbeni wethu.
Ixesha lokufuna ingcebiso yezonyango ngokukhawuleza
Nangona i-allergy eqhelekileyo ingeyona ingozi, ngamanye amaxesha inkqubo yomzimba yokuzikhusela inokusabela ngokugqithisileyo. Oku kubizwa ngokuba yi-'Anaphylaxis'.
I-Anaphylaxis yimeko engxamisekileyo yezonyango esongela ubomi. Ukuba wena okanye omnye umntu ufumana naziphi na kwezi mpawu zilandelayo, yiya kwicandelo lezonyango elikufutshane (ETU) ngokukhawuleza.
- Ukudumba kwemilebe, ulwimi, okanye ubuso
- Ubunzima bokuphefumla
- Ubunzima bokuginya
- Ukurhawuzelela okanye ukubomvu kwesikhumba emzimbeni wonke
- Intlungu yesisu, ukuhlanza, okanye urhudo
- Ukuqina kwesifuba okanye isandi sokukhala kwekhwelo
- Ukuziva unesizungu okanye ubuthathaka
Ngamaxesha anje, kubaluleke kakhulu ukuba ungoyiki kwaye ufune unyango ngoko nangoko.
Umyalezo Wokuya Ekhaya
- IiBasophils luhlobo olubalulekileyo lweeseli ezimhlophe zegazi kwinkqubo yethu yomzimba yokulwa nee-allergies kunye nosulelo olubangelwa zizinambuzane.
- I-Histamine, ekhutshwa ngabo, yimbangela yeempawu ezininzi ze-allergies, ezinje ngokurhawuzelelwa nokudumba.
- Ukuba inqanaba lakho le-basophil kwingxelo yegazi lakho lingaphaya komlinganiselo oqhelekileyo, musa ukoyika uze uthethe nogqirha wakho. Ngokuqhelekileyo unobangela unokuba yinto elula.
- Ukuba ufumana iimpawu ze-allergy ezinzima ezifana nobunzima bokuphefumla kunye nokudumba kobuso, yingxamiseko leyo. Yiya kwiSebe lezeMpilo eziNgxamisekileyo lesibhedlele (ETU) ngokukhawuleza.
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