Impumlo yakho isoloko ivalekile, kunzima ukuphefumla, awukwazi ukuvumba okanye ukungcamla nantoni na, uhlala ukhupha impumlo egobhozayo... Ngaba ubusoloko unengxaki yezi mpawu ixesha elide? Mhlawumbi unobangela woku yi-rhinosinusitis engapheliyo, oku kukuvuvukala kwexesha elide kwe-sinuses okuza neethumba ezincinci (ii-polyps zempumlo) ezikhula ngaphakathi kwempumlo yakho. Nangona abantu abaninzi benokulawula oku ngee -spray zempumlo kunye neepilisi, abanye abantu abaphili ngokupheleleyo nokuba bathatha ixesha elingakanani olu nyango. Namhlanje, siza kuthetha ngonyango olutsha olunokunceda abantu abanjalo, kwaye lusebenza ngendlela eyahlukileyo. Olu lunyango lwe-injection olubizwa ngokuba yi-Xolair.
Okokuqala, makhe sibone ukuba yintoni i-sinusitis ene-polyps yempumlo?
Ngamafutshane, imingxunya egcwele umoya ekhakhayini ejikeleze impumlo yethu ibizwa ngokuba zii-sinuses. I-rhinosinusitis engapheliyo kuxa ii-sinuses kunye nolwelo lwempumlo luvuvukala kwaye ludumba ixesha elide, luhlala ixesha elingaphezu kweenyanga ezi-3. Xa oku kuvutha kuqhubeka, ukukhula okuncinci, okuthambileyo ( ii-polyps ) ezibonakala njengeediliya ziqala ukukhula kwezinye iindawo zolwelo.
Uninzi lwexesha, ezi polyps azibangeli zimpawu. Kodwa ngamanye amaxesha, ziyakhula zize ziqale ukuvala iimpumlo kunye neempumlo. Kulapho ke iingxaki ziqala khona.
- Ukuxinana kwempumlo : Impumlo iziva ivalekile rhoqo.
- Impumlo evuzayo: Ukuphuma rhoqo kwe-mucus.
- Ukulahlekelwa yivumba nencasa : Awunakukwazi ukuvumba incasa yokutya okanye ivumba lentyatyambo.
- Intlungu yeSinus : Xa i-mucus ingakwazi ukuphuma kwimingxuma ye-sinus, inokuqokelelana, ibangele intlungu kunye noxinzelelo. Ngamanye amaxesha, ezi zinokosuleleka .
Eyona nto iphambili ekunyangeni le meko kukunciphisa ukudumba empumlweni nakwiisinuses. Emva koko iipolyps ziya kuncipha kwaye iimpawu ziya kuqala ukuncipha.
Isebenza njani i-Xolair vaccine?
Eli yeza libizwa ngokuba yiXolair liqulathe isithako esisebenzayo i-omalizumab. Isenzo salo sikhethekile kakhulu. Lijolise ngqo kwinxalenye yenkqubo yomzimba wethu yokuzikhusela.
Cinga ngemizimba yethu njengenqaba. Xa i-allergen ingena kule nqaba, "abalindi" bomzimba wethu baqalisa ukusebenza ngokukhawuleza baze baqale ukuyilwa. Omnye waba "balindi" yiproteni ebizwa ngokuba yi -Immunoglobulin E (IgE) . Kubantu abanale meko, lo mlindi, obizwa ngokuba yi-IgE, usebenza kakhulu. Usabela kakhulu nakwizinto ezincinci, nto leyo ebangela ukudumba okungeyomfuneko kunye nokuvuvukala ngaphakathi empumlweni.
Into eyenziwa yi-Xolair vaccine kukuthintela ukusebenza kweproteni ye-IgE esebenza kakhulu. Kufana nokuthomalalisa umlindi oxhalabileyo. Xa i-IgE iyeka ukusebenza, impendulo ye-allergy kunye nokudumba, ukubomvu, kunye ne-mucus ebangelayo kuyalawulwa. Oku kubangela ukuba ii-polyps zempumlo zinciphe kwaye iimpawu ziqale ukuphucuka.
Ngamafutshane, i-Xolair liyeza lanamhlanje elijolise kwimpendulo yomzimba ebangela iimpawu, endaweni yokuzicinezela.
Ngubani ofanelekileyo kolu nyango?
Asinguye wonke umntu onesi sifo onikwa i-Xolair ngaxeshanye. Unyango ludla ngokwenziwa inyathelo ngenyathelo.
| Amanyathelo onyango | Inkcazo |
|---|---|
| Inyathelo Lokuqala: IiCorticosteroids Zangaphakathi Kwempumlo | Abantu abaninzi banikwa ezi spray kuqala. Zinceda ekunciphiseni ukudumba empumlweni. Ukuba iimpawu azilawuleki emva kweenyanga ezimbalwa uzisebenzisa, dlulela kwinyathelo elilandelayo. |
| Inyathelo lesiBini: Iipilisi ze-steroid zexesha elifutshane (ii-Oral Corticosteroids) | Kwiimeko ezinzima zeempawu, ugqirha wakho unokukunika iipilisi ze-steroid zexesha elifutshane. |
| Ezinye iindlela: Utyando | Abanye abantu bade bafune utyando lokususa ii-polyps zeempumlo. |
| Ukuqwalasela unyango lweXolair | Ugqirha ucinga ngolu nyango lokugonya olubizwa ngokuba yiXolair njengolunye ukhetho olufanelekileyo kwabo basaphethwe ziimpawu ezinzima nangona sele kudlule unyango olukhankanyiweyo apha ngasentla. |
Ingaba eli yeza liyasebenza ngokwenene?
Ewe. Kuye kwenziwa iimvavanyo ezimbini ezinkulu zeklinikhi, i-POLYP 1 kunye ne-POLYP 2, ukuqinisekisa ukusebenza kakuhle kwale yeza. Bonke abathathi-nxaxheba kwezi zilingo yayingabantu ababesebenzisa i-nasal spray imihla ngemihla kodwa babesahlushwa ziimpawu.
Iziphumo zibonise ukuba abo bafumene ugonyo lweXolair babenenani eliphantsi kakhulu lee-polyps zeempumlo . Iimpawu zabo zokuxinana kweempumlo nazo zehle kakhulu.
Isetyenziswa njani iXolair? Kwaye iza kuphola ngokukhawuleza kangakanani?
I-Xolair yinaliti engamanzi. Ifakwa ngaphantsi kwesikhumba . Ihlala inikwa rhoqo kwiiveki ezi-2 ukuya kwezi-4 . Ukuba ufuna kangaphi kwaye ungakanani kuya kugqitywa ngugqirha wakho ngokusekelwe kubunzima bakho kunye namanqanaba e-IgE egazini.
- Iidosi zokuqala ezimbalwa: Uza kunikwa iidosi zokuqala ezimbalwa zale mithi phantsi kweliso likagqirha esibhedlele okanye eklinikhi. Oku kukujonga naziphi na iimpembelelo ze-allergy ezinokwenzeka kwabanye abantu.
- Emva koko ekhaya: Ukuba awunangxaki, ngemvume kagqirha wakho, ungaqeqeshwa ukuba uzinike olu gonyo ekhaya. Kukho isixhobo esilula ukusisebenzisa, esizalisiweyo kwangaphambili esibizwa ngokuba yi-"autoinjector" sale nto.
- Iziphumo: Uya kubona ukuphucuka okuthile kwiimpawu zakho kwinyanga yokuqala yokuqalisa unyango. Iimpawu zingaqhubeka ziphucuka kwiinyanga ezimbalwa ezizayo.
Eyona nto ibalulekileyo kukuba, ungaze uyeke ukusebenzisa la mayeza okanye naluphi na olunye unyango olunikiweyo ngaphandle kokuthetha nogqirha wakho, nokuba iimpawu zakho ziyaphucuka. Ukuba wenza njalo, iimpawu zakho zinokubuya.
Masifunde ngemiphumo emibi kunye nokhuseleko.
Njengazo zonke amayeza, kukho ithuba lokuba nemiphumo emibi. Nangona kunjalo, iziphumo ebezingalindelekanga ezibi kakhulu azifumaneki.
Okubaluleke kakhulu kukuba, abanye abantu baba ne-allergy enkulu (i-anaphylaxis) emva kokuthatha idosi yokuqala.Oku kunokubangela ubunzima ngequbuliso bokuphefumla, ukudumba, kunye nesiyezi. Le yimeko engxamisekileyo.
Yiyo loo nto uhlala ufumana idosi yakho yokuqala esibhedlele okanye ekliniki ngenxa yaloo ngozi. Emva koko, ukuba kukho ingxaki, kukho abasebenzi bezonyango abaqeqeshiweyo ukuyinyanga. Ngoko ke akufuneki ukhathazeke ngayo.
Ngaphandle koku, iziphumo ebezingalindelekanga ezincinci ezifana nokubomvu, ukurhawuzelela, kunye nentlungu zinokwenzeka kwindawo efakwe kuyo inaliti. Ukuba ufumana naziphi na iimpawu ezingaqhelekanga, yazisa ugqirha wakho ngoko nangoko.
Umyalezo Wokuya Ekhaya
- I-sinusitis engapheliyo ene-nasal polyps (CRSwNP) ayisiyongqele iqhelekileyo, kodwa yimeko yexesha elide.
- I-Xolair lunyango lwanamhlanje olujovayo olucingelwa abantu abangasabeliyo kunyango oluqhelekileyo (izitshizi zempumlo, iipilisi ze-steroid).
- Oku kuthintela ukusebenza kweproteni ebizwa ngokuba yi-IgE, ebandakanyeka kwiimpendulo zomzimba ze-allergy, kwaye kunciphisa ukudumba kwempumlo kunye nee-polyps.
- Olu lugonyo olunikwa phantsi kwesikhumba rhoqo emva kweeveki ezi-2-4. Umthamo wokuqala kufuneka unikwe phantsi kweliso likagqirha.
- Ukuba unale mpawu okanye ufuna ukufunda okungakumbi ngolu nyango, kubaluleke kakhulu ukuthetha nogqirha wakho.
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