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Ake siqale sibone, iyini i-CPK?
I-CPK isifinyezo. Igama layo eliphelele yi- Creatine Phosphokinase . Lena yi-enzyme ekhona ngokwemvelo emaseli omzimba wethu. Kalula nje, i-enzyme uhlobo lweprotheni olusheshisa izinqubo ezahlukene zamakhemikhali emzimbeni wethu. Umsebenzi oyinhloko wale enzyme ye-CPK ukusiza amaseli ethu akhiqize amandla. Njengophethiloli wemoto, imisipha yethu idinga amandla ukuze isebenze. Le enzyme ye-CPK ibalulekile enkambisweni yokukhiqiza lawo mandla. Le enzyme ye-CPK itholakala ezindaweni ezahlukene emzimbeni wethu. Kuye ngokuthi ikuphi, ihlukaniswe ngezinhlobo ezintathu eziyinhloko.- I-CPK-1 (CPK-BB): Lokhu kutholakala kakhulu ebuchosheni nasemaphashini.
- I-CPK-2 (CPK-MB): Lokhu kutholakala kakhulu emisipheni yenhliziyo, okungukuthi, enhliziyweni yethu.
- I-CPK-3 (CPK-MM): Lena iyona eningi kakhulu. Itholakala emisipheni yamathambo emizimbeni yethu.
Ngakho-ke iyini i-CPK test?
Ukuhlolwa kwe-CPK kuyindlela elula kakhulu yokuhlola igazi. Kulinganisa inani eliphelele le-CPK egazini lakho. Kubizwa nangokuthi ukuhlolwa kwe-CK. Akudingi ukulungiselela okuningi. Kuhilela nje ukuthatha isampula encane yegazi emthanjeni osengalweni yakho. Ungase uzizwe ubuhlungu obuncane lapho kufakwa inaliti, kodwa lokho kuvamile. Ngezinye izikhathi, ikakhulukazi uma uyisiguli esisesibhedlela, ukuhlolwa kungaphindwa njalo ezinsukwini ezimbili kuya kwezintathu. Lokhu kungenxa yokuthi kwezinye ukulimala, kungathatha izinsuku ezimbili ukuthi amazinga e-CPK akhuphuke, ngakho udokotela wakho angase afune ukuqapha ukuthi amazinga akhuphuka futhi ehle kanjani. Uma umbiko ubonisa ukuthi izinga lakho eliphelele le-CPK liphezulu, udokotela wakho angayala ukuhlolwa kwe-CPK isoenzymes ngokulandelayo.Kungenzeka ukuthi ukuhlolwa okubizwa ngokuthi i-CPK-1, i-CPK-2, kanye ne-CPK-3, esikhulume ngakho ngaphambilini, kungasetshenziswa ukuthola ukuthi yiluphi uhlobo lwe-CPK-1, i-CPK-2, kanye ne-CPK-3 oluningi kakhulu egazini. Lokhu kungasiza ekunqumeni ukuthi umonakalo usebuchosheni, enhliziyweni, noma emisipheni.
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Check Availability →Kungani ucelwa ukuthi wenze ukuhlolwa kwe-CPK?
Njengoba amazinga e-CPK angasinika umbono wempilo yemisipha yethu, inhliziyo, kanye nobuchopho, udokotela wakho angancoma lokhu kuhlolwa uma unezimpawu ezihlobene nalezi zitho zomzimba. Isibonelo, uma unezimpawu zokuhlaselwa yinhliziyo , njengobuhlungu besifuba, ungase ucelwe ukuthi wenze ukuhlolwa kwe-CPK kanye nezinye izivivinyo. Ikakhulukazi njengoba izinga le-CPK-MB liphakeme, kungasiza ekuqinisekiseni ukuthi ngabe ukuhlaselwa yinhliziyo. Futhi, lokhu kuhlolwa kubaluleke kakhulu uma unezinkinga zemisipha . Udokotela wakho angacabangela lokhu kuhlolwa uma unezimpawu ezilandelayo:- Ubuhlungu bemisipha obuqhubekayo
- Ubuthakathaka bemisipha, ukudinwa
- Ukuqaqamba kwemisipha okuvamile
- Umchamo omnyama (njengamanzi etiye)
- Ukuba ndikindiki noma ukulahlekelwa umuzwa emzimbeni
- Ukulahlekelwa ibhalansi ngenkathi uhamba (izinkinga zokulinganisela)
Liyini inani elijwayelekile lezinga le-CPK?
Izinga elijwayelekile lamazinga e-CPK kumuntu omdala onempilo liphakathi kwama-microgram ayi-10 kuya kwangu-120 ngelitha (10 kuya ku-120 mcg/l).Kodwa nansi into okufanele uyikhumbule nakanjani . Lolu hlu olujwayelekile lungahluka kancane kusuka kwelinye ilabhorethri kuya kwelinye. Lokhu kungenxa yomehluko omncane emishinini nasezindleleni abazisebenzisayo. Ngakho-ke, kungcono ukuqhathanisa inani elisembikweni wakho 'ne-Reference Range' noma 'Normal Range' enikezwe yilelo labhorethri.Ngaphezu kwalokho, leli nani lingahluka kuye ngobulili bakho, uhlanga, nokuthi uvivinya umzimba ongakanani nokuthi unemisipha engakanani. Isibonelo, amadoda ngokuvamile anamazinga e-CPK aphezulu kancane kunabesifazane.
Kusho ukuthini ukuthi izinga le-CPK liphakeme?
Amazinga e-CPK aphezulu kunokuvamile angaba uphawu lwezinkinga ezahlukene zempilo. Kuye ngokuthi hlobo luni lwe-CPK oluphakanyisiwe, ungathola umbono oqondile wokuthi inkinga ikuphi.| Uhlobo lwe-CPK | Isitho/uhlelo oluhilelekile | Izimo ezingabangela ukuthi izinga likhuphuke |
|---|---|---|
| I-CPK-1 (BB) | Ubuchopho namaphaphu | Ukuquleka, ukufa uhlangothi, ukulimala kobuchopho, izimila zobuchopho, ukuphazamiseka kwamaphaphu, kanye nokushaqeka ngogesi. |
| I-CPK-2 (MB) | Inhliziyo | Ukuhlaselwa yinhliziyo, ukuhlinzwa kwenhliziyo okuvulekile, ukulimala kwenhliziyo ngengozi, i-myocarditis, ukushaqeka ngogesi. |
| I-CPK-3 (MM) | Imisipha yesistimu yamathambo | Ukuwohloka kwemisipha, ukulimala kokuphahlazeka, ukuvivinya umzimba ngokweqile, ukulimala kwemisipha ngenxa yokungasebenzi kahle isikhathi eside (i-rhabdomyolysis), kanye nemithi ethile. |
Ezinye izizathu
Amazinga e-CPK angakhushulwa ngezinye izizathu ezingahlobene ngqo nemisipha, inhliziyo, noma ubuchopho. Isibonelo:- Isifo se-thyroid (Hypothyroidism noma Hyperthyroidism )
- Ukwehluleka kwezinso
- Ezinye izimo ezithelelanayo
- Ezinye izifo zamahomoni (isib. Isifo sika-Addison, Isifo sika-Cushing)
- Izifo zamasosha omzimba (isib. isifo samathambo esibizwa nge-Rheumatoid arthritis, i-Lupus)
- Ukuzikhandla ngokweqile
- Umjovo
- Imithi ethile, ikakhulukazi imithi yokwehlisa i-cholesterol efana nama-statin, utshwala, kanye neminye imithi.
Ingabe kukhona izinto okufanele uzicabangele ngaphambi kokuhlolwa?
Akukho ukulungiselela okukhethekile okudingekayo ukuze kuhlolwe i-CPK, kodwa kubalulekile ukutshela udokotela wakho nganoma yimiphi imithi, amavithamini kanye notshwala owuthathayo .Ngoba eminye imithi nezinto zingathinta amazinga e-CPK. Isibonelo, uma usebenzisa okulandelayo, amazinga akho e-CPK angase abonakale ephakeme:- Utshwala
- Imithi yokwehlisa i-cholesterol (ama-statin)
- Ezinye izidakamizwa zokubulala izinzwa
- Ama-steroid
- Izidakamizwa ezifana ne-cocaine
Umlayezo Wokuya Nawe Ekhaya
- I-CPK iyi-enzyme ebalulekile emzimbeni wethu. Amazinga aphezulu ale enzyme egazini angaba uphawu lokulimala kwemisipha, inhliziyo, noma izicubu zobuchopho.
- Kodwa-ke, akuwona wonke amazinga e-CPK aphakanyisiwe, okusho ukuthi kukhona isifo esibi. Singakhuphuka futhi ngenxa yezizathu ezilula njengokuzivocavoca ngokweqile, imithi ethile, noma umjovo.
- Ngakho-ke, ungalokothi uzihlole noma uthuke ngokusekelwe embikweni we-CPK.
- Into ebaluleke kakhulu ukuthola umbiko wakho bese ukhuluma nodokotela wakho ngakho. Nguye kuphela ongakunikeza iseluleko esingcono kakhulu ngemva kokucabangela izimpawu zakho, indlela ophila ngayo, nazo zonke ezinye izici, futhi uma kudingeka, wenze ezinye izivivinyo.
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