Xa umntu kusapho lwethu eqala ukulahlekelwa yinkumbulo yakhe njengoko ekhula, sonke sicinga ngayo njenge -Alzheimer's . Yinyani le, i-Alzheimer's yenye yezona zifo zixhaphakileyo ze-dementia. Kodwa ubusazi na, kukho enye imeko ebizwa ngokuba yiLewy Body Dementia , okanye i-LBD . Oku kukwachaphazela nabantu abangaphezu kweminyaka engama-50 ubudala. Ngoko ke namhlanje, masithethe ngokuba yintoni i-LBD.
Ngamafutshane, yintoni iLewy Body Dementia (LBD)?
Khawuthelekelele ukuba iiseli ezikwingqondo yethu zinxibelelana ngeekhemikhali . Imizimba yeLewy yiiproteni ezingaqhelekanga eziqokelelana kwiingqondo zethu. Xa ziqokelelana, ziphazamisa ukusebenza okuqhelekileyo kwengqondo. Ngokukodwa, zinokuphazamisa izinto ezininzi, kubandakanya inkumbulo yethu, intshukumo, amandla okucinga, imo yeemvakalelo kunye nokuziphatha.
Le meko ye-LBD inokwenzeka ngeendlela ezimbini eziphambili:
1. I-Dementia enemizimba kaLewy: Oku kuqala ngeengxaki zomzimba, ezinje ngobunzima bokuhamba nokuhamba. Emva konyaka, iingxaki zokukhumbula nokucinga ezifana nesifo sika-Alzheimer ziyavela. Kunokubakho nemibono engabonakaliyo.
2. Isifo sikaParkinson's dementia: Kule meko, iingxaki zokunyakaza (iimpawu zikaParkinson) ziqala ukubonakala. Iingxaki zenkumbulo kunye nokucinga ziqala ukubonakala kamva kakhulu kwesi sifo.
Into ebalulekileyo kukuba okwangoku akukho nyango lwe-LBD. Nangona kunjalo, kukho iindlela zokulawula iimpawu kunye nokubonelela ngoncedo lwexeshana.
Yintoni umahluko phakathi kwe-LBD, i-Alzheimer's, kunye ne-Parkinson's?
Nangona ezi zifo zintathu zinokubonakala zifana, kukho umahluko ocacileyo phakathi kwazo. Ukuqaphela la mahluko kubalulekile kunyango.
| Ukuthelekisa isifo | Umahluko ophambili phakathi kwee-LBD |
|---|---|
| Isifo sika-Alzheimer | Ngokungafaniyo ne-Alzheimer's, i-LBD ayilahli inkumbulo yexesha elifutshane ekuqaleni. Kwi-LBD, izakhono zokuqwalasela kunye nokucinga ziyatshintshatshintsha ngokukhawuleza (ezinokwahluka imihla ngemihla, iyure neyure). Ukungaboni kakuhle kuqhelekile kwizigaba zokuqala ze-LBD, kodwa kwi-Alzheimer's, kwenzeka emva kwexesha kwesi sifo. |
| Isifo sikaParkinson | Kwisifo sikaParkinson, iingxaki zenkumbulo (i-dementia) zenzeka kuphela emva kokuba isifo sifikelele kwinqanaba eliphezulu kakhulu, okanye ngamanye amaxesha asifiki kwaphela. Nangona kunjalo, kwi-LBD , iingxaki zenkumbulo ziqala ngexesha elinye nobunzima bokushukuma okanye kungekudala emva koko . |
| Ukuziphatha ebuthongweni | Uphawu olukhethekileyo lwe-LBD yi -REM sleep behavior disorder . Oku kulapho udlala khona amaphupha akho ngelixa ulele (umz., ukuba ulwa emaphupheni akho, ushukumisa amalungu akho, okanye uwe ebhedini). Olu luphawu lokuqala lwe-LBD. |
Izizathu kunye nezinto ezibangela umngcipheko we-LBD
Ezi protein clumps, ezibizwa ngokuba yiLewy bodies, zenziwe ngohlobo lweprotein olubizwa ngokuba yi-alpha-synuclein. Xa ziqokelelana engqondweni, ziphazamisana nokuveliswa kweekhemikhali ezimbini ezibalulekileyo engqondweni yethu.
- I-Acetylcholine: Oku kuchaphazela inkumbulo yethu nokufunda kwethu.
- I-Dopamine : Oku kulawula intshukumo yethu, imeko yethu, kunye nokulala kwethu.
Izazinzulu azikayazi kakuhle ukuba kutheni le mizimba kaLewy iqokelelana engqondweni, okanye kutheni abanye abantu kuphela abaphuhlisa i-LBD.
Ingaba esi sisifo esizuzwe njengelifa? I-LBD ayithathwa njengesifo esizuzwe njengelifa. Nangona kunjalo, ukuba umntu kusapho lwakho une-LBD, usenokuba nethuba elincinci lokuba nayo.
Izinto eziphambili ezibangela umngcipheko:
- Ukwaluphala (ingakumbi abantu abaneminyaka engaphezu kwama-50 ubudala)
- Ukuba nezinye iimeko zonyango, ezifana nesifo sikaParkinson
- Ukuba nembali yosapho ene-LBD
- Amadoda anamathuba amaninzi okufumana usulelo
Zithini iimpawu ze-LBD?
Ayingabo bonke abaguli abaneempawu ezifanayo. Ezinye iimpawu zinokuba zincinci, ngelixa ezinye zinokuba nzima. Nazi ezinye zeempawu eziqhelekileyo.
| Uhlobo oluneempawu | Imizekelo |
|---|---|
| Imiphumo kubuchule bokucinga | Ubunzima bokwenza izigqibo, ukungakwazi ukugweba umgama, ukuncipha kwengqwalasela, ukuncipha kwenkumbulo, ukudideka ngendawo okanye ixesha, ubunzima bokusebenza ngamanani. |
| Imiphumo ekuhambeni | Ukurhuqa iinyawo xa uhamba, ukuqina, izandla ezingcangcazelayo, ukulahlekelwa kukulinganisela nokuwa, ukugoba phambili, ukubhala ngesandla okuncinci, ubunzima bokuginya. |
| Imiphumo ekulaleni | Ingxaki yokuziphatha kokulala kweREM, ukozela kakhulu emini, ukungalali kakuhle, kunye nesifo semilenze engaphumliyo. |
| Impembelelo kwimo yengqondo | Uxinzelelo, ixhala, ukungazinzi, ukubona okanye ukuva izinto ezingekhoyo, uloyiko olungaqhelekanga (umz., ukucinga ukuba kukho umntu oza kundenzakalisa). |
| Ezinye iimpawu | Ukudinwa nokuquleka, utshintsho kuxinzelelo lwegazi, ukuqhina, ukungakwazi ukulawula umchamo, kunye nokuncipha kwevumba. |
Ukulila okanye ukuhleka okungalawulekiyo
Abanye abantu abane-LBD banokukhala okanye bahleke ngequbuliso ngaphandle kwesizathu esicacileyo. Oku kwaziwa ngokwezonyango njenge-'pseudobulbar affect (PBA).' Oku akusiyo imvakalelo yabo yokwenyani, kodwa yinto eyenzeka ngokungalawulekiyo ngenxa yesifo.
Uxilongo kunye nonyango
Akukho vavanyo lunye olunokuxilonga i-LBD. Ngenxa yokuba iimpawu zifana nezinye izifo, kunokuba nzima koogqirha ukuxilonga, ingakumbi kwizigaba zokuqala. Ke ngoko, ugqirha uya kwenza iimvavanyo ezininzi ukuqinisekisa ukuba akukho ezinye iimeko .
- Uvavanyo lwenkqubo yomzimba neyemithambo-luvo
- Uvavanyo lwegazi (ukujonga amanqanaba eevithamini okanye amahomoni)
- Iiskeni zobuchopho (i-CT scan, i-MRI scan)
- Uvavanyo olulinganisa inkumbulo kunye nobuchule bokucinga
- Uvavanyo lokulala
Ukuba sithetha ngonyango,
Okwangoku akukho nyango okanye unyango lwe-LBD, kodwa kukho amayeza kunye nonyango olunokunceda ukulawula iimpawu nokwenza ubomi bube lula.
Isilumkiso: Amanye amayeza okubulala iingqondo asetyenziselwa ukunyanga isifo se-Alzheimer anokuba yingozi kubantu abane-LBD. Angenza iimpawu zibe zimbi ngakumbi. Ngoko ke, qiniseka ukuba uthetha nogqirha wakho ngaphambi kokuba usebenzise naliphi na iyeza.
Ukongeza kumayeza, unyango olufana nonyango lomzimba, unyango lomsebenzi, kunye neengcebiso lunokubonelela ngesiqabu esikhulu kumguli nakubanakekeli bakhe.
Ukuhlala ne-LBD
I-LBD ngumceli mngeni kwisigulana nakwintsapho yaso, kodwa ngocwangciso olufanelekileyo kunye nenkxaso, uhambo lunokwenziwa lube lula.
- Qinisekisa ukhuseleko: Susa imiqobo kwiindawo zokuhamba ekhaya. Faka ii-bars zokubamba kwigumbi lokuhlambela.
- Fumana inkxaso: Thetha nosapho kunye nabahlobo ngale nto. Fumana uncedo lobuchwephesha ukuba kuyimfuneko.
- Cwangcisa kwangaphambili: Yenza izigqibo zonyango nezemali kwangaphambili, ngokweminqweno yesigulana.
- Yonwaba: Yenza isigulana sibandakanyeke kwizinto esizithandayo nesizithandayo.
Ubomi obuqhelekileyo bomntu one-LBD bumalunga neminyaka eyi-7-8 ukususela ekuqaleni kweempawu. Nangona kunjalo, oku kunokwahluka kakhulu kumntu nomntu. Abanye abantu baphila ukuya kuthi ga kwiminyaka engama-20.
Umyalezo Wokuya Ekhaya
- I-Dementia ayisoloko ibizwa ngokuba sisifo sika-Alzheimer. I-Lewy body dementia (LBD) nayo yimeko eqhelekileyo.
- Ukongeza kwiingxaki zenkumbulo, utshintsho kwintshukumo, ebuthongweni, nakwindlela yokuziphatha lunokubonwa kwi-LBD kwizigaba zokuqala.
- Ingxaki yokuziphatha kokulala kwe-REM kunye nokubona izinto ezingekhoyo kunokuba ziimpawu eziphambili ze-LBD.
- Nangona kungekho nyango lupheleleyo lwesi sifo, umgangatho wobomi besigulana unokuphuculwa ngokulawula iimpawu.
- Ukuba umntu osondeleyo kuwe uhlangabezana nezi mpawu, kubaluleke kakhulu ukubona ugqirha ofanelekileyo ngokukhawuleza kwaye ufumane ingcebiso.
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