Siyazi ukuba ukuhlala nesifo sikaParkinson kunokuba nzima ngamanye amaxesha. Akulula ukudlula usuku unezinto ezinje ngokungcangcazela nokuhamba kancinci. Ngoko ke oogqirha banika amayeza ahlukeneyo okulawula ezi mpawu. Namhlanje siza kuthetha ngelinye lamayeza akhethekileyo, iTolcapone. Eli asiloyeza elihlala linikwa lodwa. Linikwa ne-levodopa- carbidopa , eliliyeza eliphambili lesifo sikaParkinson . Ngamafutshane, lifana "nomncedisi" onceda iyeza eliphambili.
Yintoni iTolcapone?
Kulungile, masiyibeke ngokulula le nto. Isifo sikaParkinson senzeka xa imveliso yekhemikhali ebizwa ngokuba yidopamine engqondweni yethu incipha. Iyeza olinikwayo, elibizwa ngokuba yi-levodopa-carbidopa, lisebenza ngokungena engqondweni lize liyiguqule ibe yi-dopamine. Kodwa ngamanye amaxesha ukusebenza kweli yeza kunokuncipha kancinci kancinci.
Kulapho i-tolcapone ingena khona. I-Tolcapone liyeza elikudidi lwamayeza abizwa ngokuba yi-COMT inhibitors. Isebenza ngokuthintela umzimba ekuqhekezeni i-levodopa ngaphambi kokuba ifike engqondweni. Oku kuthetha ukuba ivumela uninzi lwamayeza akho aphambili ukuba afike engqondweni, nto leyo eyenza isebenze ngakumbi kwaye ihlale ixesha elide . Igama lophawu lwale chiza yiTasmar.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba uqale ukusebenzisa eli yeza, kubaluleke kakhulu ukwazisa ugqirha wakho ngemeko yakho yempilo epheleleyo. Eli yeza lisenokudibana nezinye iimeko zempilo. Ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelele ugqirha wakho.
| Imeko/inyani yempilo | Kutheni kufuneka uxelele ugqirha? |
|---|---|
| Isifo sesibindi | Eli yeza linokuchaphazela isibindi, ngoko ke kubalulekile ukwazi ukuba kukho ubuthathaka besibindi. |
| Isifo sezintso | Amayeza asuswa emzimbeni zizintso. Ngoko ke, ugqirha kufuneka azi ngokusebenza kwezintso. |
| Isigulo sengqondo | Ngamanye amaxesha la mayeza anokuchaphazela imeko yengqondo, ngoko ke kubalulekile ukukwazi oku kwangaphambili. |
| I-sleep apnea okanye i-narcolepsy | Eli yeza linokubangela ukuba abanye abantu balale ngequbuliso, ngoko ke kubalulekile ukuxela naziphi na iimeko ezinjalo. |
| Ukuba uzama ukukhulelwa, ukhulelwe, okanye ungumama oncancisayo | Qiniseka ukuba uyayikhankanya le nto, kuba kufuneka ulumke ngakumbi ekusebenziseni amayeza kwezi meko. |
| Ukunganyamezelani kwamanye amayeza, ukutya, okanye idayi | Xelela ugqirha wakho ngazo naziphi na izinto ezibangela ukuba ungabi namdla. |
Ulisebenzisa njani kanye kanye eli yeza?
Indlela yokusebenzisa eli yeza ilula kakhulu.
- Ginya ipilisi ngeglasi yamanzi.
- Thatha idosi emiselweyo ngexesha elimiselweyo, njengoko ugqirha emisele. Ungayithatha ngaphambi okanye emva kokutya.
- Ungaze uthathe okungaphezulu koko ugqirha akuxelele kona.
- Musa ukuyeka ukuthatha amayeza ngequbuliso ngaphandle kwengcebiso kagqirha. Ukwenza njalo kunokubangela impendulo ebuhlungu.
- Ukuba unika abantwana eli yeza, thetha nogqirha wabantwana ngalo.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Kodwa ukuba sele kuza kufuneka uthathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe amayeza amaninzi kunokuba ucinga, fowunela iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye yiya kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane. Phatha oku njengengxamiseko.
Khumbula, eli yeza limiselwe wena wedwa. Musa ukulinika omnye umntu, nokuba uneempawu ezifanayo nezakho.
Amanye amayeza anokusebenza kunye nale mayeza
Kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo, kuquka iivithamini kunye neemveliso zezityalo , kuba amanye amayeza anokuchaphazela i-tolcapone.
| Yintoni enokubangela iingxaki? | Inkcazo |
|---|---|
| Musa ukuzithatha ezi zinto kunye nantoni na. | |
| Amayeza ohlobo lwe-MAOI | Amayeza okudakumba afana noMarplan, uNardil, kunye noParnate. |
| Yazisa ugqirha wakho ukuba uzithatha ezi zinto kunye. | |
| Utywala | Utywala bunokutshintsha imiphumo yamayeza kwaye bunyuse ukozela. |
| Amayeza okulala okanye ukuxhalaba | Ukozela kunye nokuncipha kwengqwalasela kunokwanda. |
| I-Apomorphine, i-dobutamine, i-dopamine, i-epinephrine, i-isoproterenol, i-norepinephrine | La ngamayeza anikwa izifo ezifana nesifo sentliziyo kunye noxinzelelo lwegazi oluphezulu. |
| I-Warfarin | Iyeza elinikwa ukuthintela ukuqhekeka kwegazi. |
| Okunye | I-Desipramine, i-linezolid, i-methyldopa, kunye neyeza zokudambisa iintlungu ezibangelwa ziziyobisi. |
Zeziphi izinto ekufuneka uzilumkele xa usebenzisa amayeza?
Kubaluleke kakhulu ukuqaphela utshintsho emzimbeni wakho ngelixa usebenzisa eli yeza.
- Ukudinwa kunye nokulinganisela : WenaUsenokuziva unesiyezi okanye unesizungu. Ngoko ke , musa ukuqhuba okanye ukusebenzisa oomatshini ude wazi ukuba eli yeza likuchaphazela njani. Lumka xa usukuma kwindawo ohleli kuyo, ingakumbi ukuba sele ukhulile.
- Ukuqala kokulala ngequbuliso: Oku kubi ngakumbi. Abanye abantu banokulala ngequbuliso bengakhange bozele, ngelixa bethetha, besitya, okanye beqhuba imoto. Ukuba oku kwenzeka, xelela ugqirha wakho ngoko nangoko.
- Iminqweno engalawulekiyo: Abanye abantu banokuba neminqweno engalawulekiyo yokungcakaza, ukulala nomntu, ukuchitha imali ngokungeyomfuneko, okanye ukutya kakhulu ngelixa besebenzisa la mayeza. Oku akumele kube neentloni ngako, kwaye kunokuba yimpembelelo embi yeyeza. Ukuba ufumana nayiphi na kwezi, xelela ugqirha wakho ngoko nangoko.
- Ukhathalelo lolusu: Ngelixa usela eli yeza, soloko ujonga ulusu lwakho ukuba alunatshintsho kwiimoles zakho ezikhoyo okanye iimoles ezintsha. Ukuba ubona naluphi na utshintsho, xelela ugqirha wakho .
- Umlomo owomileyo : Ukuba umlomo wakho womile, ukuhlafuna itshungama engenaswekile, ukufunxa iilekese ezingenaswekile, kunye nokusela amanzi amaninzi kunokunceda.
Zeziphi iziphumo ebezingalindelekanga endinokuzifumana?
Njengalo naliphi na iyeza, i-tolcapone inokuba nemiphumo emibi. Eminye iyingozi, eminye ixhaphakile.
| Iimpawu zomonakalo wesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, isicaphucaphu, ukungabi namdla wokutya. |
| Iimpawu zomonakalo wemisipha | Umchamo omnyama, ubunzima bokuchama, ubuthathaka obungaqhelekanga, iintlungu zemisipha. |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ezinye iimpawu ezinzulu | Urhudo olukhulu, ukubona izinto ezingekhoyo, ukozela ngequbuliso, ukulahlekelwa zingqondo nokuwa, ukungcangcazela okungalawulekiyo kwamalungu afana neengalo, imilenze, ubuso nentamo. |
| Urhudo | Isiyezi |
| Intloko ebuhlungu | Ukulahlekelwa ngumdla wokutya |
| Isicaphucaphu | Ingxaki yokulala |
Uligcina phi iyeza?
- Gcina kude nokufikelela kwabantwana .
- Gcina kubushushu begumbi (phakathi kwama-20-25 degrees Celsius).
- Gcina isiciko sebhotile sivaliwe kakuhle.
- Lahla naliphi na iyeza elishiyekileyo emva komhla wokuphelelwa.
Umyalezo Wokuya Ekhaya
- I-Tolcapone sisiyobisi esincedisayo esongeza ukusebenza kakuhle kweyeza lakho eliphambili leParkinson.
- Ngaphambi kokuba uqale eli yeza, xelela ugqirha wakho ngazo zonke iimeko zempilo onazo kunye nawo onke amayeza owasebenzisayo.
- Musa ukuyeka ukuthatha amayeza ngequbuliso ngaphandle kwengcebiso kagqirha.
- Lumka xa ufikelwa bubuthongo ngequbuliso, umnqweno ongalawulekiyo, kunye neempawu zokonakala kwesibindi. Ukuba ubona nayiphi na kwezi, xelela ugqirha wakho ngoko nangoko.
- Ukuba ukrokrela ukuba usela kakhulu, yiya kwiZiko loLwazi lweePoisons leSizwe okanye kwiSebe leeNgxamiseko lesibhedlele esikufutshane (ETU).
- Thetha ngokukhululekileyo nogqirha wakho ngayo nayiphi na imibuzo okanye izinto ezikuxhalabisayo.
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