Akucaci ukuba ubhubhane weCovid-19 ubutshintshe kangakanani ubomi bethu. Nangona sonke sigonyiwe kwaye sikhuselekile kancinci, le ntsholongwane ayizukuhlala kude . Iindidi ezintsha zayo ziyavela ngamanye amaxesha. Usenokukhumbula iAlpha, iBeta, kunye nohlobo lwe -Omicron olusandula ukuthethwa ngalo. Njengoko intsholongwane iqhubeka nokutshintsha ngale ndlela, imigonyo yangoku ngamanye amaxesha isenokungasebenzi kakuhle ekuthinteleni ukusasazeka kwezi ntsholongwane zintsha. Ngoko ke ukongeza koku, uphando lwenziwa kwihlabathi liphela ngezinye iindlela ezikhuselekileyo. Ngokukodwa, ngeendlela zokuthintela ukusasazeka kosulelo kwiindawo ezixineneyo ezifana nemidlalo emikhulu kunye neekonsathi zomculo. Olu lolunye uphando esiza kuthetha ngalo namhlanje. Olu luphando malunga ne-spray yempumlo ephuhliswayo yeCovid.
Yintoni le spray yempumlo yeCovid yovavanyo?
Nangona oku kusesekwinqanaba lophando, iNational Institute of Allergy and Infectious Diseases (NIAID) eMelika iqhuba olu phando. Ngamafutshane, eli liyeza elinokutshizwa empumlweni. Okwangoku, uvavanyo kwiimpuku lubonise iziphumo eziphumeleleyo kakhulu . Ngoko ke abaphandi bakholelwa ukuba linamandla okubonelela ngokhuseleko olufanayo ebantwini.
Ekubeni oku kusekutsha, akukho lwazi lungako malunga neenzuzo okanye iziphumo ebezingalindelekanga. Kodwa abaphandi bakholelwa ukuba ukusebenzisa isitshizi empumlweni emva kokuba umntu evezwe yintsholongwane kunokunceda ukuthintela usulelo. Bakwakholelwa ukuba ukuba isitshizi sisetyenziswa kungekudala emva kokuvezwa (kwiiyure ezili-12) , singasetyenziswa njengonyango lwakwangoko.
Kolu vavanyo, iimpuku zafakwa i-receptors zeeseli zabantu zaza zachanabeka kwi-Covid virus, oko kukuthi i-SARS-CoV-2 virus. Emva koko, zanikwa i-spray equlethe le molekyuli ikhethekileyo ebizwa ngokuba yi-N-0385. Kwafunyaniswa ukuba le molekyuli inokukhusela iimpuku kwintsholongwane. Ayipheleli nje apho, ifunyenwe isebenza kakuhle kungekuphela nje kwi-Covid virus yokuqala, kodwa nakwiindidi zayo ezahlukeneyo .
Yintoni umahluko phakathi konyango olukhoyo kunye nesi sitshizi sempumlo?
Njengoko kuvela iintlobo ezintsha zentsholongwane ye-COVID-19, ukusebenza kakuhle kwezinye iindlela zonyango ze-antibody ezikhoyo kuyehla. Enyanisweni, ezinye iindlela zonyango ze-antibody ezikhoyo azikwazi nokulawula uhlobo lwe-Omicron. Ukongeza, ezi ndlela zonyango ze-antibody zibiza kakhulu. Kunzima ukuzenza, ukuzithutha, nokuzigcina. Kwaye zinokunikwa ngugqirha kuphela. Ngenxa yezi zizathu, kunzima kumazwe anengeniso ephantsi ukufikelela kwezi ndlela zonyango.
Nangona kunjalo, esi sitshizi sitsha sempumlo sahlukile ngokupheleleyo. Jonga itheyibhile engezantsi ukuze usithelekise.
| Uphawu | Isifutho seempumlo | Unyango lwe-Antibody |
|---|---|---|
| Ixabiso kunye nemveliso | Ayibizi kakhulu kwaye ingaveliswa kusetyenziswa iintsholongwane eziqhelekileyo ezifana ne-E. coli. | Ibiza kakhulu. Kunzima ukuyivelisa, ukuyithutha, nokuyigcina. |
| Indawo yokugcina izinto | Ingagcinwa izinzile nokuba kubushushu obuphezulu. | Kufuneka igcinwe phantsi kweemeko ezikhethekileyo zokukhenkcisa. |
| Kusetyenziswa kwanjani | Ungayitshiza empumlweni yakho ngokwakho. Kulula kakhulu. | Ifanele inikwe kuphela ngemithambo yegazi (IV) ngugqirha. |
| Ngokuchasene neentlobo ngeentlobo | Uvavanyo lubonise ukuba iyasebenza kwiintlobo ezininzi ezintsha. | Impumelelo xa kuthelekiswa nezinye iintlobo ezintsha (umz. i-Omicron) iphantsi. |
Abaphandi banethemba lokuba kungekudala baza kuyenza le spray yempumlo ifumaneke nakwiikhemesti eziqhelekileyo.
Isebenza njani le spray yempumlo?
Ukuze siqonde oku, kufuneka siqale siqonde indlela intsholongwane yeCovid engena ngayo emizimbeni yethu. Khawuthelekelele ukuba intsholongwane yeCovid ifana nebhola encinci enezipikili ezininzi. Sibiza ezi zipikili ngokuba ziiproteni zespike . Iiseli zomzimba wethu zinee-receptors ezifanelana ngqo nezi zipikili, njengesitshixo esifanelana nesitshixo. Xa ezi proteni zespike kwintsholongwane zincamathela kwezi receptors kwiiseli zethu, intsholongwane ingena kwiiseli kwaye isenze sigule.
Unyango lwangoku lwee-antibody luyazithintela ezi protein ze-spike. Kodwa njengoko intsholongwane itshintsha kwaye kuvela iintlobo ezintsha, imo yezi protein ze-spike nayo iyatshintsha kancinci. Emva koko unyango lwakudala alukwazi ukuyibona kakuhle imo entsha.
Nangona kunjalo, esi sitshizi sitsha sempumlo sisebenza ngendlela eyahlukileyo. Asijolisi kwiproteni ye-spike yentsholongwane, kodwa sijolisa kwi-receptor kwiiseli zethu . Ngamanye amazwi, into eyenziwa sesi sitshizi kukuvala okwethutyana loo 'tshixi'. Emva koko, nokuba 'isitshixo' sentsholongwane sahluke kangakanani na, akukho sitshixo sokusifaka. Yiyo loo nto sikholelwa ukuba le ndlela ingaphumelela nakwiintlobo ezintsha.
Ingaba oku kuphumelele ngokwenene?
Kuvavanyo ukuza kuthi ga ngoku, oku kube yimpumelelo enkulu kwiimpuku. Xa iimpuku ezosulelwe yiCovid zanikwa esi sitshizi se-N-0385, ama-70% asinda , kwaye imiphunga yazo ayibonakali ngathi yonakele. Kolunye uvavanyo, xa iimpuku ezili-10 zanikwa olu nyango kangangeentsuku ezi-4, zonke ezili-10 zasinda. Nangona kunjalo, yinye kuphela kwiimpuku ezingama-20 ezanikwa isisombululo sesaline esiqhelekileyo endaweni yolu nyango eyasindayo.
Olu vavanyo lubonisa ukuba olu lunyango oluthembisayo kakhulu. Inyathelo elilandelayo kukuqalisa uvavanyo ebantwini. Nje ukuba imali efunekayo ifunyenwe, siya kukwazi ukwazi ukuba oku kukhuselekile kwaye kusebenza kangakanani ebantwini. Ke ngoko, kufuneka sikhumbule ukuba oku kusesekwinqanaba lophando. Kodwa kunamandla okuba sisixhobo esinamandla ekulweni neentsholongwane ezifana neCovid kwixesha elizayo.
Umyalezo Wokuya Ekhaya
- Uphando luyaqhubeka okwangoku malunga ne-spray yempumlo yokukhusela intsholongwane ye-COVID-19. Oku kusavavanywa.Isesekwinqanaba lophando kwaye ayikakhutshwa ukuze isetyenziswe luluntu.
- Uvavanyo olusebenzisa iimpuku luvelise iziphumo eziphumeleleyo kakhulu, kwaye lusebenze ekuthinteleni usulelo kwaye lukwasebenza njengonyango kwizigaba zokuqala zosulelo.
- Kulindeleke ukuba esi sitshizi sibe yindlela engabizi kakhulu, elula ukuyisebenzisa, kwaye kulula ukuyigcina endaweni yonyango lwee-antibody olubiza kakhulu nolunzima ukulusebenzisa okwangoku.
- Oku kusebenza ngokuvala okwethutyana ii-receptors kwiiseli zethu ezivumela intsholongwane ukuba ingene, endaweni yokujonga iindawo ezithile zentsholongwane. Oku kwenza ukuba ikwazi ukusebenza ngakumbi kwiintlobo ezintsha zentsholongwane.
- Kuphela emva kovavanyo lwabantu apho impumelelo yokwenene kunye nokhuseleko lwale nto lunokuqinisekiswa. Ke ngoko, nangona kukho ithemba ngekamva, kubaluleke kakhulu ukufumana amayeza okugonya akhoyo kunye nokulandela iingcebiso zempilo.
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